KR20020026469A - 엽산 생합성을 위한 코리네박테리움 글루타미쿰으로부터의유전자, 및 미생물에 의한 엽산 생산에 있어서 그들의 용도 - Google Patents

엽산 생합성을 위한 코리네박테리움 글루타미쿰으로부터의유전자, 및 미생물에 의한 엽산 생산에 있어서 그들의 용도 Download PDF

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Publication number
KR20020026469A
KR20020026469A KR1020017016565A KR20017016565A KR20020026469A KR 20020026469 A KR20020026469 A KR 20020026469A KR 1020017016565 A KR1020017016565 A KR 1020017016565A KR 20017016565 A KR20017016565 A KR 20017016565A KR 20020026469 A KR20020026469 A KR 20020026469A
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South Korea
Prior art keywords
polypeptide
folic acid
seq
amino acids
deletion
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KR1020017016565A
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English (en)
Korean (ko)
Inventor
마티아스 맥
카린 헤르브스테르
Original Assignee
악사론 바이오사이언스 아게
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Application filed by 악사론 바이오사이언스 아게 filed Critical 악사론 바이오사이언스 아게
Publication of KR20020026469A publication Critical patent/KR20020026469A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1235—Diphosphotransferases (2.7.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020017016565A 1999-06-25 2000-06-23 엽산 생합성을 위한 코리네박테리움 글루타미쿰으로부터의유전자, 및 미생물에 의한 엽산 생산에 있어서 그들의 용도 KR20020026469A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19929363.5 1999-06-25
DE19929363A DE19929363A1 (de) 1999-06-25 1999-06-25 Gene aus Corynebacterium glutamicum für die Folsäurebiosynthese und ihr Einsatz zur mikrobiellen Herstellung von Folsäure
PCT/EP2000/005864 WO2001000845A1 (fr) 1999-06-25 2000-06-23 Genes de corynebacterium glutamicum pour la biosynthese de l'acide folique et leur utilisation pour la production microbienne d'acide folique

Publications (1)

Publication Number Publication Date
KR20020026469A true KR20020026469A (ko) 2002-04-10

Family

ID=7912677

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020017016565A KR20020026469A (ko) 1999-06-25 2000-06-23 엽산 생합성을 위한 코리네박테리움 글루타미쿰으로부터의유전자, 및 미생물에 의한 엽산 생산에 있어서 그들의 용도

Country Status (8)

Country Link
EP (1) EP1194565A1 (fr)
KR (1) KR20020026469A (fr)
CN (1) CN1371418A (fr)
AU (1) AU5978200A (fr)
CA (1) CA2377458A1 (fr)
DE (1) DE19929363A1 (fr)
WO (1) WO2001000845A1 (fr)
ZA (1) ZA200200582B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1298854C (zh) 1999-07-02 2007-02-07 味之素株式会社 编码蔗糖pts酶ⅱ的dna
US6942996B2 (en) 2000-08-02 2005-09-13 Degussa Ag Isolated polynucleotide from Corynebacterium encoding a homocysteine methyltransferase
US6958228B2 (en) 2000-08-02 2005-10-25 Degussa Ag Nucleotide sequence which code for the metH gene
DE10039043A1 (de) 2000-08-10 2002-02-21 Degussa Neue für das luxR-Gen kodierende Nukleotidsequenzen
DE10039044A1 (de) 2000-08-10 2002-02-21 Degussa Neue für das IysR1-Gen kodierende Nukleotidsequenzen
DE10039049A1 (de) 2000-08-10 2002-02-21 Degussa Neue für das IysR3-Gen kodierende Nukleotidsequenzen
AU2001291658A1 (en) 2000-08-26 2002-03-13 Degussa A.G. Nucleotide sequences which code for the ccpa2 gene
US6815196B2 (en) 2000-09-02 2004-11-09 Degussa Ag Nucleotide sequences encoding o-succinylhomoserine sulfhydrylase
US6812016B2 (en) 2000-09-02 2004-11-02 Degussa Ag Nucleotide sequences which code for the metY gene
WO2002020792A1 (fr) 2000-09-09 2002-03-14 Degussa Ag Sequences nucleotidiques codant le gene dep33
US6759224B2 (en) 2000-09-09 2004-07-06 Degussa Ag Nucleotide sequences which code for the sahH gene
DE10045496A1 (de) 2000-09-14 2002-03-28 Degussa Neue für das ptsi-Gen kodierende Nukleotidsequenzen
DE10055869A1 (de) 2000-11-10 2002-05-29 Degussa Neue für das nadA-Gen kodierende Nukleotidsequenzen
DE10055870A1 (de) 2000-11-10 2002-05-29 Degussa Neue für das nadC-Gen kodierende Nukleotidsequenzen
EP1262541A1 (fr) * 2001-05-28 2002-12-04 Stichting Top-Instituut Voedselwetenschappen Production de l'acide folique biodisponible
US7468262B2 (en) 2003-05-16 2008-12-23 Ajinomoto Co., Inc. Polynucleotides encoding useful polypeptides in corynebacterium glutamicum ssp. lactofermentum
CN1952114B (zh) * 2005-10-20 2010-04-14 浙江爱迪亚营养科技开发有限公司 一种谷氨酸棒杆菌及其应用于制备烟酰胺的方法
CN109810991B (zh) * 2019-03-02 2021-11-12 昆明理工大学 二氢蝶酸合酶基因folP的用途
CN111235169A (zh) * 2020-02-03 2020-06-05 昆明理工大学 一种GTP环化水解酶I基因folE及应用
CN112852844A (zh) * 2021-03-05 2021-05-28 昆明理工大学 羟甲基二氢蝶呤焦磷酸激酶基因folK的用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968788A (en) * 1995-08-28 1999-10-19 Toray Industries, Inc. Method for producing folic acid

Also Published As

Publication number Publication date
DE19929363A1 (de) 2000-12-28
CN1371418A (zh) 2002-09-25
WO2001000845A1 (fr) 2001-01-04
CA2377458A1 (fr) 2001-01-04
EP1194565A1 (fr) 2002-04-10
AU5978200A (en) 2001-01-31
ZA200200582B (en) 2003-03-26

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