KR20010110346A - 편광을 사용하여 조직을 이미지화시키는 방법 - Google Patents

편광을 사용하여 조직을 이미지화시키는 방법 Download PDF

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Publication number
KR20010110346A
KR20010110346A KR1020017009360A KR20017009360A KR20010110346A KR 20010110346 A KR20010110346 A KR 20010110346A KR 1020017009360 A KR1020017009360 A KR 1020017009360A KR 20017009360 A KR20017009360 A KR 20017009360A KR 20010110346 A KR20010110346 A KR 20010110346A
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KR
South Korea
Prior art keywords
light
tissue
fiber
polarization
backscattered
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Ceased
Application number
KR1020017009360A
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English (en)
Korean (ko)
Inventor
스티븐 에프. 풀검
Original Assignee
추후제출
뉴턴 래보러토리스, 인코포레이티드
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Publication of KR20010110346A publication Critical patent/KR20010110346A/ko
Ceased legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
    • G02B23/2407Optical details
    • G02B23/2461Illumination
    • G02B23/2469Illumination using optical fibres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064Constructional details of the endoscope body
    • A61B1/00071Insertion part of the endoscope body
    • A61B1/0008Insertion part of the endoscope body characterised by distal tip features
    • A61B1/00096Optical elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064Constructional details of the endoscope body
    • A61B1/00071Insertion part of the endoscope body
    • A61B1/0008Insertion part of the endoscope body characterised by distal tip features
    • A61B1/00097Sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • A61B1/00172Optical arrangements with means for scanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • A61B1/00186Optical arrangements with imaging filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
    • G02B23/2407Optical details
    • G02B23/2423Optical details of the distal end
    • G02B23/243Objectives for endoscopes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N2021/4704Angular selective
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N2021/4792Polarisation of scatter light
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/49Scattering, i.e. diffuse reflection within a body or fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Astronomy & Astrophysics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Instruments For Viewing The Inside Of Hollow Bodies (AREA)
  • Endoscopes (AREA)
  • Eye Examination Apparatus (AREA)
KR1020017009360A 1999-01-25 2000-01-25 편광을 사용하여 조직을 이미지화시키는 방법 Ceased KR20010110346A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11722199P 1999-01-25 1999-01-25
US60/117,221 1999-01-25
PCT/US2000/001764 WO2000043750A2 (en) 1999-01-25 2000-01-25 Imaging of tissue using polarized light

Publications (1)

Publication Number Publication Date
KR20010110346A true KR20010110346A (ko) 2001-12-13

Family

ID=22371613

Family Applications (1)

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KR1020017009360A Ceased KR20010110346A (ko) 1999-01-25 2000-01-25 편광을 사용하여 조직을 이미지화시키는 방법

Country Status (9)

Country Link
EP (1) EP1153280A2 (enExample)
JP (1) JP2002535645A (enExample)
KR (1) KR20010110346A (enExample)
CN (1) CN1341209A (enExample)
AU (1) AU2628200A (enExample)
CA (1) CA2371782A1 (enExample)
HK (1) HK1041727A1 (enExample)
NZ (1) NZ513118A (enExample)
WO (1) WO2000043750A2 (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002018658A1 (en) * 2000-08-14 2002-03-07 Oralscan Laboratories, Inc. Detection of epithelial dysplasia
AU2002240572A1 (en) * 2001-03-02 2002-09-19 Anant Agrawal System and method for determining tissue characteristics
JP2005515472A (ja) * 2002-01-18 2005-05-26 ニユートン・ラボラトリーズ・インコーポレーテツド 分光診断方法とシステム
EP1466163A2 (en) * 2002-01-18 2004-10-13 Newton Laboratories, Inc. Spectroscopic diagnostic methods and system
AU2002337504A1 (en) * 2002-06-08 2003-12-22 Kwon Soo Ha Method for protein chip analysis by using surface plasmon resonance spectroscopic imaging technology
CN102866116B (zh) * 2003-06-04 2015-08-19 广东永士达医疗科技有限公司 利用光的传播模式测量物质中的光学不均匀性和其他属性
JP4535697B2 (ja) * 2003-07-23 2010-09-01 オリンパス株式会社 生体組織の光散乱観測内視鏡装置
US7289205B2 (en) * 2003-09-19 2007-10-30 The General Hospital Corporation Fluorescence polarization imaging devices and methods
CN100443041C (zh) * 2004-05-26 2008-12-17 吴冈 具有测量功能的内窥镜系统及其测量方法
US20070167835A1 (en) * 2005-07-25 2007-07-19 Massachusetts Institute Of Technology Tri modal spectroscopic imaging
JP2009511909A (ja) * 2005-10-11 2009-03-19 デユーク・ユニバーシテイ 内視鏡による角度分解低コヒーレンス干渉法のためのシステムおよび方法
JP4796652B2 (ja) * 2007-02-20 2011-10-19 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ サンプル中の光学的な深さを評価する光学装置
CN101641043B (zh) * 2007-03-12 2012-01-11 皇家飞利浦电子股份有限公司 用于复合上皮早期癌症的诊断和分期的系统
CN100506150C (zh) * 2007-04-28 2009-07-01 马剑文 活体组织光学检测装置及其工作方法
DE202008009859U1 (de) * 2007-12-21 2009-03-05 Berthold Technologies Gmbh & Co. Kg Vorrichtung zur wahlweisen Messung von insbesondere Lumineszenz- und/oder Fluoreszenzstrahlung
JP4575474B2 (ja) * 2008-06-11 2010-11-04 国立大学法人東京工業大学 生体組織識別装置および方法
JP5191831B2 (ja) * 2008-07-23 2013-05-08 オリンパスメディカルシステムズ株式会社 被検体観測装置及び被検体観測装置の作動方法
KR101109968B1 (ko) 2008-07-23 2012-02-17 올림푸스 메디칼 시스템즈 가부시키가이샤 피검체 관측 장치 및 피검체 관측 방법
JP2010025867A (ja) * 2008-07-23 2010-02-04 Olympus Medical Systems Corp 被検体観測装置及び被検体観測方法
EP2373979A1 (en) * 2008-12-02 2011-10-12 Koninklijke Philips Electronics N.V. Sensor device for detecting target particles by frustrated total internal reflection
JP5532479B2 (ja) * 2010-03-31 2014-06-25 住友化学株式会社 金型検査方法、防眩製品ヘイズ予測方法および防眩製品反射像鮮明度予測方法
WO2012057150A1 (ja) * 2010-10-29 2012-05-03 オリンパス株式会社 光学測定装置およびプローブ
WO2013011778A1 (ja) * 2011-07-15 2013-01-24 オリンパスメディカルシステムズ株式会社 プローブ
WO2013133339A1 (ja) * 2012-03-07 2013-09-12 オリンパス株式会社 測定プローブ
RU2014140612A (ru) * 2012-03-08 2016-04-27 Конинклейке Филипс Н.В. Устройство определения свойства ткани
WO2013152395A1 (en) 2012-04-13 2013-10-17 Baker Idi Heart & Diabetes Institute Holdings Limited Atherosclerotic plaque detection
CN104219988A (zh) * 2012-05-25 2014-12-17 奥林巴斯医疗株式会社 测量探头
EP2896350A4 (en) * 2012-09-13 2016-06-15 Olympus Corp MEASURING PROBE AND BIOLOGICAL OPTICAL MEASURING SYSTEM
DE102012221527A1 (de) * 2012-11-26 2014-06-12 Heine Optotechnik Gmbh & Co Kg Optisches Diagnoseinstrument
US9921148B2 (en) * 2013-04-21 2018-03-20 Mobileodt Ltd. Polarized light imaging apparatus and methods thereof for separating light from a surface of a sample its deeper diffuse layers
CN104280350B (zh) * 2013-07-03 2018-06-01 庞小峰 一种特殊锐化的癌症早期诊断和治疗效果检查的装置
KR101503272B1 (ko) 2013-07-26 2015-03-18 연세대학교 원주산학협력단 관절염 진단을 위한 다중 모드 광 영상장치
CN106725250A (zh) * 2017-01-09 2017-05-31 清华大学深圳研究生院 一种头端调制的内窥偏振成像系统及测量方法
KR102881023B1 (ko) * 2017-08-31 2025-11-04 메탈렌츠 인코포레이티드 투과성 메타표면 렌즈 통합
EP3799626A4 (en) 2018-07-02 2022-03-30 Metalenz, Inc. Metasurfaces for laser speckle reduction
CN120255032A (zh) 2019-07-26 2025-07-04 梅特兰兹股份有限公司 孔隙-超表面和混合折射-超表面成像系统
CN113075097A (zh) * 2021-03-22 2021-07-06 厦门理工学院 一种基于散射光偏振检测的粒径测量方法、装置及设备
WO2024205646A2 (en) 2022-03-31 2024-10-03 Metalenz, Inc. Polarization sorting metasurface microlens array device

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61129554A (ja) * 1984-11-28 1986-06-17 Nippon Paint Co Ltd 散乱光測定装置
GB8701521D0 (en) * 1987-01-23 1993-12-01 British Aerospace Multi-parameter imaging polarimeter
US4953978A (en) * 1989-03-03 1990-09-04 Coulter Electronics Of New England, Inc. Particle size analysis utilizing polarization intensity differential scattering
ATE160170T1 (de) * 1991-02-22 1997-11-15 Coulter Corp Verfahren und vorrichtung zum reihensichten mikroskopischer zellen unter verwendung von techniken zur streuung polarisierten lichts
JPH0611439A (ja) * 1992-06-29 1994-01-21 Olympus Optical Co Ltd 生体組織の酸素代謝測定装置
US5672875A (en) * 1992-07-15 1997-09-30 Optix Lp Methods of minimizing scattering and improving tissue sampling in non-invasive testing and imaging
US5421339A (en) * 1993-05-12 1995-06-06 Board Of Regents, The University Of Texas System Diagnosis of dysplasia using laser induced fluoroescence
JP3451515B2 (ja) * 1995-04-06 2003-09-29 オムロン株式会社 光学式センサ装置
US5788639A (en) * 1995-07-13 1998-08-04 Lucid Technologies, Inc. Confocal imaging through thick dermal tissue
US5719399A (en) * 1995-12-18 1998-02-17 The Research Foundation Of City College Of New York Imaging and characterization of tissue based upon the preservation of polarized light transmitted therethrough
JPH09297099A (ja) * 1996-05-07 1997-11-18 Hitachi Ltd カラー近接場光学顕微鏡
JPH10246697A (ja) * 1997-03-03 1998-09-14 Nikon Corp 光学的検査方法及び光学的検査装置

Also Published As

Publication number Publication date
HK1041727A1 (zh) 2002-07-19
JP2002535645A (ja) 2002-10-22
NZ513118A (en) 2004-02-27
CA2371782A1 (en) 2000-07-27
WO2000043750A2 (en) 2000-07-27
AU2628200A (en) 2000-08-07
WO2000043750A3 (en) 2000-11-23
EP1153280A2 (en) 2001-11-14
WO2000043750A9 (en) 2001-08-30
CN1341209A (zh) 2002-03-20

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