JP2002535645A - 偏光を使用する組織の画像形成 - Google Patents

偏光を使用する組織の画像形成

Info

Publication number
JP2002535645A
JP2002535645A JP2000595125A JP2000595125A JP2002535645A JP 2002535645 A JP2002535645 A JP 2002535645A JP 2000595125 A JP2000595125 A JP 2000595125A JP 2000595125 A JP2000595125 A JP 2000595125A JP 2002535645 A JP2002535645 A JP 2002535645A
Authority
JP
Japan
Prior art keywords
light
tissue
backscattered
fiber
illumination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000595125A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002535645A5 (enExample
Inventor
フルガム，ステイーブン・エフ
Original Assignee
ニユートン・ラボラトリーズ・インコーポレーテツド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ニユートン・ラボラトリーズ・インコーポレーテツド filed Critical ニユートン・ラボラトリーズ・インコーポレーテツド
Publication of JP2002535645A publication Critical patent/JP2002535645A/ja
Publication of JP2002535645A5 publication Critical patent/JP2002535645A5/ja
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
    • G02B23/2407—Optical details
    • G02B23/2461—Illumination
    • G02B23/2469—Illumination using optical fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064—Constructional details of the endoscope body
    • A61B1/00071—Insertion part of the endoscope body
    • A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
    • A61B1/00096—Optical elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064—Constructional details of the endoscope body
    • A61B1/00071—Insertion part of the endoscope body
    • A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
    • A61B1/00097—Sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00172—Optical arrangements with means for scanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00186—Optical arrangements with imaging filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
    • G02B23/2407—Optical details
    • G02B23/2423—Optical details of the distal end
    • G02B23/243—Objectives for endoscopes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/4704—Angular selective
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/4792—Polarisation of scatter light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Astronomy & Astrophysics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Instruments For Viewing The Inside Of Hollow Bodies (AREA)
  • Endoscopes (AREA)
  • Eye Examination Apparatus (AREA)
JP2000595125A 1999-01-25 2000-01-25 偏光を使用する組織の画像形成 Pending JP2002535645A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11722199P 1999-01-25 1999-01-25
US60/117,221 1999-01-25
PCT/US2000/001764 WO2000043750A2 (en) 1999-01-25 2000-01-25 Imaging of tissue using polarized light

Publications (2)

Publication Number Publication Date
JP2002535645A true JP2002535645A (ja) 2002-10-22
JP2002535645A5 JP2002535645A5 (enExample) 2007-03-29

Family

ID=22371613

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000595125A Pending JP2002535645A (ja) 1999-01-25 2000-01-25 偏光を使用する組織の画像形成

Country Status (9)

Country Link
EP (1) EP1153280A2 (enExample)
JP (1) JP2002535645A (enExample)
KR (1) KR20010110346A (enExample)
CN (1) CN1341209A (enExample)
AU (1) AU2628200A (enExample)
CA (1) CA2371782A1 (enExample)
HK (1) HK1041727A1 (enExample)
NZ (1) NZ513118A (enExample)
WO (1) WO2000043750A2 (enExample)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005040175A (ja) * 2003-07-23 2005-02-17 Olympus Corp 生体組織の光散乱観測内視鏡装置及び観測方法
JP2007511243A (ja) * 2003-09-19 2007-05-10 ザ・ジェネラル・ホスピタル・コーポレイション 蛍光偏極撮像装置及び方法
JP2009300131A (ja) * 2008-06-11 2009-12-24 Tokyo Institute Of Technology 生体組織識別装置および方法
JP2010022717A (ja) * 2008-07-23 2010-02-04 Olympus Medical Systems Corp 被検体観測装置及び被検体観測方法
JP2010025867A (ja) * 2008-07-23 2010-02-04 Olympus Medical Systems Corp 被検体観測装置及び被検体観測方法
JP2010519520A (ja) * 2007-02-20 2010-06-03 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ サンプル中の光学的な深さを評価する光学装置
JP2011214976A (ja) * 2010-03-31 2011-10-27 Sumitomo Chemical Co Ltd 金型検査装置、金型検査方法、防眩製品ヘイズ予測方法および防眩製品反射像鮮明度予測方法
WO2012057150A1 (ja) * 2010-10-29 2012-05-03 オリンパス株式会社 光学測定装置およびプローブ
WO2013011778A1 (ja) * 2011-07-15 2013-01-24 オリンパスメディカルシステムズ株式会社 プローブ
WO2013133339A1 (ja) * 2012-03-07 2013-09-12 オリンパス株式会社 測定プローブ
WO2013175879A1 (ja) * 2012-05-25 2013-11-28 オリンパスメディカルシステムズ株式会社 測定プローブ
WO2014042156A1 (ja) * 2012-09-13 2014-03-20 オリンパス株式会社 測定プローブおよび生体光学測定システム
KR101503272B1 (ko) 2013-07-26 2015-03-18 연세대학교 원주산학협력단 관절염 진단을 위한 다중 모드 광 영상장치
JP2015514446A (ja) * 2012-03-08 2015-05-21 コーニンクレッカ フィリップス エヌ ヴェ 組織の特性を決定するための器具
US9345385B2 (en) 2008-07-23 2016-05-24 Olympus Corporation Subject observation apparatus and subject observation method

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WO2002071026A2 (en) * 2001-03-02 2002-09-12 Spectrx, Inc. System and method for determining tissue characteristics
AU2001294997A1 (en) * 2000-08-14 2002-03-13 Oralscan Laboratories, Inc. Detection of epithelial dysplasia
JP2005515473A (ja) * 2002-01-18 2005-05-26 ニユートン・ラボラトリーズ・インコーポレーテツド 分光診断方法とシステム
US7333189B2 (en) 2002-01-18 2008-02-19 Pentax Corporation Spectroscopic diagnostic methods and system
WO2003104775A1 (en) * 2002-06-08 2003-12-18 Korea Basic Science Institute Method for protein chip analysis by using surface plasmon resonance spectroscopic imaging technology
EP1639331B1 (en) * 2003-06-04 2016-08-24 Samsung Electronics Co., Ltd. Measurements of optical inhomogeneity and other properties in substances using propagation modes of light
CN100443041C (zh) * 2004-05-26 2008-12-17 吴冈 具有测量功能的内窥镜系统及其测量方法
US20070167835A1 (en) * 2005-07-25 2007-07-19 Massachusetts Institute Of Technology Tri modal spectroscopic imaging
US7595889B2 (en) * 2005-10-11 2009-09-29 Duke University Systems and methods for endoscopic angle-resolved low coherence interferometry
WO2008110968A1 (en) * 2007-03-12 2008-09-18 Koninklijke Philips Electronics N.V. A system, computer-readable medium, method, and use for combined epithelial early cancer diagnosis and staging
CN100506150C (zh) * 2007-04-28 2009-07-01 马剑文 活体组织光学检测装置及其工作方法
DE202008009859U1 (de) * 2007-12-21 2009-03-05 Berthold Technologies Gmbh & Co. Kg Vorrichtung zur wahlweisen Messung von insbesondere Lumineszenz- und/oder Fluoreszenzstrahlung
CN102227625A (zh) * 2008-12-02 2011-10-26 皇家飞利浦电子股份有限公司 用于通过受抑全内反射来探测目标颗粒的传感器装置
EP2836128B1 (en) 2012-04-13 2023-03-15 Baker Heart and Diabetes Institute Atherosclerotic plaque detection
DE102012221527A1 (de) * 2012-11-26 2014-06-12 Heine Optotechnik Gmbh & Co Kg Optisches Diagnoseinstrument
CN105814434A (zh) 2013-04-21 2016-07-27 莫拜尔欧西特有限公司 用于将来自样本表面的光和来自其更深漫射层的光分离的偏振光成像装置及其方法
CN104280350B (zh) * 2013-07-03 2018-06-01 庞小峰 一种特殊锐化的癌症早期诊断和治疗效果检查的装置
CN106725250A (zh) * 2017-01-09 2017-05-31 清华大学深圳研究生院 一种头端调制的内窥偏振成像系统及测量方法
JP7461294B2 (ja) * 2017-08-31 2024-04-03 メタレンズ，インコーポレイテッド 透過型メタサーフェスレンズ統合
US12140778B2 (en) 2018-07-02 2024-11-12 Metalenz, Inc. Metasurfaces for laser speckle reduction
US11978752B2 (en) 2019-07-26 2024-05-07 Metalenz, Inc. Aperture-metasurface and hybrid refractive-metasurface imaging systems
AU2021321456B2 (en) 2020-08-04 2022-06-30 Baker Heart and Diabetes Institute Guidewire sensing apparatus
EP4275080A4 (en) 2021-01-06 2024-11-13 Metalenz, Inc. SELF-ALIGNED NANOPILLAR COATINGS AND METHODS OF PREPARATION
CN113075097A (zh) * 2021-03-22 2021-07-06 厦门理工学院 一种基于散射光偏振检测的粒径测量方法、装置及设备
CN118591827A (zh) 2021-12-17 2024-09-03 梅特兰兹股份有限公司 通过照明和成像的抗欺骗面部识别
EP4500265A2 (en) 2022-03-31 2025-02-05 Metalenz, Inc. Polarization sorting metasurface microlens array device
US12699207B2 (en) 2022-10-05 2026-08-04 Metalenz, Inc. Shared-aperture camera system and calibration method

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JPS61129554A (ja) * 1984-11-28 1986-06-17 Nippon Paint Co Ltd 散乱光測定装置
JPH03505131A (ja) * 1989-03-03 1991-11-07 コウルター　エレクトロニクス　オブ　ニュー　イングランド，インコーポレイテッド 偏光強度差分散乱を使用する粒子寸法分析
JPH0611439A (ja) * 1992-06-29 1994-01-21 Olympus Optical Co Ltd 生体組織の酸素代謝測定装置
JPH06505099A (ja) * 1991-02-22 1994-06-09 クールター　コーポレイション 偏光光散乱手法を用いて微視的細胞をスクリーニングする方法および装置
JPH09196845A (ja) * 1995-04-06 1997-07-31 Omron Corp 光学式センサ装置
JPH09297099A (ja) * 1996-05-07 1997-11-18 Hitachi Ltd カラー近接場光学顕微鏡
JPH10246697A (ja) * 1997-03-03 1998-09-14 Nikon Corp 光学的検査方法及び光学的検査装置
US5847394A (en) * 1995-12-18 1998-12-08 Research Foundation Of City College Of New York Imaging of objects based upon the polarization or depolarization of light
JPH11506202A (ja) * 1995-06-07 1999-06-02 オプティクス エルピー 非侵入的検査及びイメージングにおける散乱を最小化し且つ組織サンプリングを改善する方法
JP2002509467A (ja) * 1996-05-20 2002-03-26 ルーサド テクノロジーズ インコーポレーテッド 厚い皮膚組織を通す共焦点画像化

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US5421339A (en) * 1993-05-12 1995-06-06 Board Of Regents, The University Of Texas System Diagnosis of dysplasia using laser induced fluoroescence

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61129554A (ja) * 1984-11-28 1986-06-17 Nippon Paint Co Ltd 散乱光測定装置
JPH03505131A (ja) * 1989-03-03 1991-11-07 コウルター　エレクトロニクス　オブ　ニュー　イングランド，インコーポレイテッド 偏光強度差分散乱を使用する粒子寸法分析
JPH06505099A (ja) * 1991-02-22 1994-06-09 クールター　コーポレイション 偏光光散乱手法を用いて微視的細胞をスクリーニングする方法および装置
JPH0611439A (ja) * 1992-06-29 1994-01-21 Olympus Optical Co Ltd 生体組織の酸素代謝測定装置
JPH09196845A (ja) * 1995-04-06 1997-07-31 Omron Corp 光学式センサ装置
JPH11506202A (ja) * 1995-06-07 1999-06-02 オプティクス エルピー 非侵入的検査及びイメージングにおける散乱を最小化し且つ組織サンプリングを改善する方法
US5847394A (en) * 1995-12-18 1998-12-08 Research Foundation Of City College Of New York Imaging of objects based upon the polarization or depolarization of light
JPH09297099A (ja) * 1996-05-07 1997-11-18 Hitachi Ltd カラー近接場光学顕微鏡
JP2002509467A (ja) * 1996-05-20 2002-03-26 ルーサド テクノロジーズ インコーポレーテッド 厚い皮膚組織を通す共焦点画像化
JPH10246697A (ja) * 1997-03-03 1998-09-14 Nikon Corp 光学的検査方法及び光学的検査装置

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005040175A (ja) * 2003-07-23 2005-02-17 Olympus Corp 生体組織の光散乱観測内視鏡装置及び観測方法
JP2007511243A (ja) * 2003-09-19 2007-05-10 ザ・ジェネラル・ホスピタル・コーポレイション 蛍光偏極撮像装置及び方法
JP2010519520A (ja) * 2007-02-20 2010-06-03 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ サンプル中の光学的な深さを評価する光学装置
JP2009300131A (ja) * 2008-06-11 2009-12-24 Tokyo Institute Of Technology 生体組織識別装置および方法
JP2010022717A (ja) * 2008-07-23 2010-02-04 Olympus Medical Systems Corp 被検体観測装置及び被検体観測方法
JP2010025867A (ja) * 2008-07-23 2010-02-04 Olympus Medical Systems Corp 被検体観測装置及び被検体観測方法
US9345385B2 (en) 2008-07-23 2016-05-24 Olympus Corporation Subject observation apparatus and subject observation method
JP2011214976A (ja) * 2010-03-31 2011-10-27 Sumitomo Chemical Co Ltd 金型検査装置、金型検査方法、防眩製品ヘイズ予測方法および防眩製品反射像鮮明度予測方法
JPWO2012057150A1 (ja) * 2010-10-29 2014-05-12 オリンパス株式会社 光学測定装置およびプローブ
US8830460B2 (en) 2010-10-29 2014-09-09 Olympus Corporation Optical measurement apparatus and probe
WO2012057150A1 (ja) * 2010-10-29 2012-05-03 オリンパス株式会社 光学測定装置およびプローブ
JP2016073687A (ja) * 2010-10-29 2016-05-12 オリンパス株式会社 光学測定装置およびプローブ
WO2013011778A1 (ja) * 2011-07-15 2013-01-24 オリンパスメディカルシステムズ株式会社 プローブ
US9107583B2 (en) 2011-07-15 2015-08-18 Olympus Medical Systems Corp. Optical measurement probe
WO2013133339A1 (ja) * 2012-03-07 2013-09-12 オリンパス株式会社 測定プローブ
JPWO2013133339A1 (ja) * 2012-03-07 2015-07-30 オリンパス株式会社 測定プローブ
US9883802B2 (en) 2012-03-07 2018-02-06 Olympus Corporation Measurement probe
JP2015514446A (ja) * 2012-03-08 2015-05-21 コーニンクレッカ フィリップス エヌ ヴェ 組織の特性を決定するための器具
US11331038B2 (en) 2012-03-08 2022-05-17 Koninklijke Philips N.V. Apparatus for determining a property of a tissue
WO2013175879A1 (ja) * 2012-05-25 2013-11-28 オリンパスメディカルシステムズ株式会社 測定プローブ
WO2014042156A1 (ja) * 2012-09-13 2014-03-20 オリンパス株式会社 測定プローブおよび生体光学測定システム
JPWO2014042156A1 (ja) * 2012-09-13 2016-08-18 オリンパス株式会社 測定プローブおよび生体光学測定システム
US10149619B2 (en) 2012-09-13 2018-12-11 Olympus Corporation Measurement probe and biological optical measurement system
KR101503272B1 (ko) 2013-07-26 2015-03-18 연세대학교 원주산학협력단 관절염 진단을 위한 다중 모드 광 영상장치

Also Published As

Publication number Publication date
WO2000043750A9 (en) 2001-08-30
HK1041727A1 (zh) 2002-07-19
CN1341209A (zh) 2002-03-20
WO2000043750A2 (en) 2000-07-27
WO2000043750A3 (en) 2000-11-23
EP1153280A2 (en) 2001-11-14
KR20010110346A (ko) 2001-12-13
AU2628200A (en) 2000-08-07
CA2371782A1 (en) 2000-07-27
NZ513118A (en) 2004-02-27

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