JP2002535645A - 偏光を使用する組織の画像形成 - Google Patents

偏光を使用する組織の画像形成

Info

Publication number
JP2002535645A
JP2002535645A JP2000595125A JP2000595125A JP2002535645A JP 2002535645 A JP2002535645 A JP 2002535645A JP 2000595125 A JP2000595125 A JP 2000595125A JP 2000595125 A JP2000595125 A JP 2000595125A JP 2002535645 A JP2002535645 A JP 2002535645A
Authority
JP
Japan
Prior art keywords
light
tissue
backscattered
fiber
illumination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000595125A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002535645A5 (enExample
Inventor
フルガム，ステイーブン・エフ
Original Assignee
ニユートン・ラボラトリーズ・インコーポレーテツド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ニユートン・ラボラトリーズ・インコーポレーテツド filed Critical ニユートン・ラボラトリーズ・インコーポレーテツド
Publication of JP2002535645A publication Critical patent/JP2002535645A/ja
Publication of JP2002535645A5 publication Critical patent/JP2002535645A5/ja
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
    • G02B23/2407—Optical details
    • G02B23/2461—Illumination
    • G02B23/2469—Illumination using optical fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064—Constructional details of the endoscope body
    • A61B1/00071—Insertion part of the endoscope body
    • A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
    • A61B1/00096—Optical elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064—Constructional details of the endoscope body
    • A61B1/00071—Insertion part of the endoscope body
    • A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
    • A61B1/00097—Sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00172—Optical arrangements with means for scanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00186—Optical arrangements with imaging filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
    • G02B23/2407—Optical details
    • G02B23/2423—Optical details of the distal end
    • G02B23/243—Objectives for endoscopes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/4704—Angular selective
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/4792—Polarisation of scatter light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Astronomy & Astrophysics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Endoscopes (AREA)
  • Eye Examination Apparatus (AREA)
  • Instruments For Viewing The Inside Of Hollow Bodies (AREA)
JP2000595125A 1999-01-25 2000-01-25 偏光を使用する組織の画像形成 Pending JP2002535645A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11722199P 1999-01-25 1999-01-25
US60/117,221 1999-01-25
PCT/US2000/001764 WO2000043750A2 (en) 1999-01-25 2000-01-25 Imaging of tissue using polarized light

Publications (2)

Publication Number Publication Date
JP2002535645A true JP2002535645A (ja) 2002-10-22
JP2002535645A5 JP2002535645A5 (enExample) 2007-03-29

Family

ID=22371613

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000595125A Pending JP2002535645A (ja) 1999-01-25 2000-01-25 偏光を使用する組織の画像形成

Country Status (9)

Country Link
EP (1) EP1153280A2 (enExample)
JP (1) JP2002535645A (enExample)
KR (1) KR20010110346A (enExample)
CN (1) CN1341209A (enExample)
AU (1) AU2628200A (enExample)
CA (1) CA2371782A1 (enExample)
HK (1) HK1041727A1 (enExample)
NZ (1) NZ513118A (enExample)
WO (1) WO2000043750A2 (enExample)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005040175A (ja) * 2003-07-23 2005-02-17 Olympus Corp 生体組織の光散乱観測内視鏡装置及び観測方法
JP2007511243A (ja) * 2003-09-19 2007-05-10 ザ・ジェネラル・ホスピタル・コーポレイション 蛍光偏極撮像装置及び方法
JP2009300131A (ja) * 2008-06-11 2009-12-24 Tokyo Institute Of Technology 生体組織識別装置および方法
JP2010025867A (ja) * 2008-07-23 2010-02-04 Olympus Medical Systems Corp 被検体観測装置及び被検体観測方法
JP2010022717A (ja) * 2008-07-23 2010-02-04 Olympus Medical Systems Corp 被検体観測装置及び被検体観測方法
JP2010519520A (ja) * 2007-02-20 2010-06-03 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ サンプル中の光学的な深さを評価する光学装置
JP2011214976A (ja) * 2010-03-31 2011-10-27 Sumitomo Chemical Co Ltd 金型検査装置、金型検査方法、防眩製品ヘイズ予測方法および防眩製品反射像鮮明度予測方法
WO2012057150A1 (ja) * 2010-10-29 2012-05-03 オリンパス株式会社 光学測定装置およびプローブ
WO2013011778A1 (ja) * 2011-07-15 2013-01-24 オリンパスメディカルシステムズ株式会社 プローブ
WO2013133339A1 (ja) * 2012-03-07 2013-09-12 オリンパス株式会社 測定プローブ
WO2013175879A1 (ja) * 2012-05-25 2013-11-28 オリンパスメディカルシステムズ株式会社 測定プローブ
WO2014042156A1 (ja) * 2012-09-13 2014-03-20 オリンパス株式会社 測定プローブおよび生体光学測定システム
KR101503272B1 (ko) 2013-07-26 2015-03-18 연세대학교 원주산학협력단 관절염 진단을 위한 다중 모드 광 영상장치
JP2015514446A (ja) * 2012-03-08 2015-05-21 コーニンクレッカ フィリップス エヌ ヴェ 組織の特性を決定するための器具
US9345385B2 (en) 2008-07-23 2016-05-24 Olympus Corporation Subject observation apparatus and subject observation method

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001294997A1 (en) * 2000-08-14 2002-03-13 Oralscan Laboratories, Inc. Detection of epithelial dysplasia
IL157158A0 (en) * 2001-03-02 2004-02-08 Spectrx Inc System and method for determining tissue characteristics
US7404929B2 (en) 2002-01-18 2008-07-29 Newton Laboratories, Inc. Spectroscopic diagnostic methods and system based on scattering of polarized light
EP1472517A1 (en) 2002-01-18 2004-11-03 Newton Laboratories, Inc. Spectroscopic diagnostic methods and system
AU2002337504A1 (en) * 2002-06-08 2003-12-22 Kwon Soo Ha Method for protein chip analysis by using surface plasmon resonance spectroscopic imaging technology
CN102866116B (zh) * 2003-06-04 2015-08-19 广东永士达医疗科技有限公司 利用光的传播模式测量物质中的光学不均匀性和其他属性
CN100443041C (zh) * 2004-05-26 2008-12-17 吴冈 具有测量功能的内窥镜系统及其测量方法
US20070167835A1 (en) * 2005-07-25 2007-07-19 Massachusetts Institute Of Technology Tri modal spectroscopic imaging
CN101326428B (zh) * 2005-10-11 2011-05-18 杜克大学 用于内窥镜的角度分辨低相干干涉测量的系统和方法
CN101641043B (zh) * 2007-03-12 2012-01-11 皇家飞利浦电子股份有限公司 用于复合上皮早期癌症的诊断和分期的系统
CN100506150C (zh) * 2007-04-28 2009-07-01 马剑文 活体组织光学检测装置及其工作方法
DE202008009859U1 (de) * 2007-12-21 2009-03-05 Berthold Technologies Gmbh & Co. Kg Vorrichtung zur wahlweisen Messung von insbesondere Lumineszenz- und/oder Fluoreszenzstrahlung
EP2373979A1 (en) * 2008-12-02 2011-10-12 Koninklijke Philips Electronics N.V. Sensor device for detecting target particles by frustrated total internal reflection
JP6398093B2 (ja) 2012-04-13 2018-10-03 ベイカー ハート アンド ダイアベーツ インスティテュート アテローム斑の検出
DE102012221527A1 (de) * 2012-11-26 2014-06-12 Heine Optotechnik Gmbh & Co Kg Optisches Diagnoseinstrument
EP2989441B1 (en) * 2013-04-21 2019-01-02 Mobileodt Ltd A polarized light imaging apparatus and associated method for separating light from a surface of a sample and its deeper layers
CN104280350B (zh) * 2013-07-03 2018-06-01 庞小峰 一种特殊锐化的癌症早期诊断和治疗效果检查的装置
CN106725250A (zh) * 2017-01-09 2017-05-31 清华大学深圳研究生院 一种头端调制的内窥偏振成像系统及测量方法
KR102881023B1 (ko) 2017-08-31 2025-11-04 메탈렌츠 인코포레이티드 투과성 메타표면 렌즈 통합
CN118707744A (zh) 2018-07-02 2024-09-27 梅特兰兹股份有限公司 用于激光散斑减少的超表面
US11978752B2 (en) 2019-07-26 2024-05-07 Metalenz, Inc. Aperture-metasurface and hybrid refractive-metasurface imaging systems
CN113075097A (zh) * 2021-03-22 2021-07-06 厦门理工学院 一种基于散射光偏振检测的粒径测量方法、装置及设备
EP4500265A2 (en) 2022-03-31 2025-02-05 Metalenz, Inc. Polarization sorting metasurface microlens array device

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61129554A (ja) * 1984-11-28 1986-06-17 Nippon Paint Co Ltd 散乱光測定装置
JPH03505131A (ja) * 1989-03-03 1991-11-07 コウルター　エレクトロニクス　オブ　ニュー　イングランド，インコーポレイテッド 偏光強度差分散乱を使用する粒子寸法分析
JPH0611439A (ja) * 1992-06-29 1994-01-21 Olympus Optical Co Ltd 生体組織の酸素代謝測定装置
JPH06505099A (ja) * 1991-02-22 1994-06-09 クールター　コーポレイション 偏光光散乱手法を用いて微視的細胞をスクリーニングする方法および装置
JPH09196845A (ja) * 1995-04-06 1997-07-31 Omron Corp 光学式センサ装置
JPH09297099A (ja) * 1996-05-07 1997-11-18 Hitachi Ltd カラー近接場光学顕微鏡
JPH10246697A (ja) * 1997-03-03 1998-09-14 Nikon Corp 光学的検査方法及び光学的検査装置
US5847394A (en) * 1995-12-18 1998-12-08 Research Foundation Of City College Of New York Imaging of objects based upon the polarization or depolarization of light
JPH11506202A (ja) * 1995-06-07 1999-06-02 オプティクス エルピー 非侵入的検査及びイメージングにおける散乱を最小化し且つ組織サンプリングを改善する方法
JP2002509467A (ja) * 1996-05-20 2002-03-26 ルーサド テクノロジーズ インコーポレーテッド 厚い皮膚組織を通す共焦点画像化

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8701521D0 (en) * 1987-01-23 1993-12-01 British Aerospace Multi-parameter imaging polarimeter
US5421339A (en) * 1993-05-12 1995-06-06 Board Of Regents, The University Of Texas System Diagnosis of dysplasia using laser induced fluoroescence

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61129554A (ja) * 1984-11-28 1986-06-17 Nippon Paint Co Ltd 散乱光測定装置
JPH03505131A (ja) * 1989-03-03 1991-11-07 コウルター　エレクトロニクス　オブ　ニュー　イングランド，インコーポレイテッド 偏光強度差分散乱を使用する粒子寸法分析
JPH06505099A (ja) * 1991-02-22 1994-06-09 クールター　コーポレイション 偏光光散乱手法を用いて微視的細胞をスクリーニングする方法および装置
JPH0611439A (ja) * 1992-06-29 1994-01-21 Olympus Optical Co Ltd 生体組織の酸素代謝測定装置
JPH09196845A (ja) * 1995-04-06 1997-07-31 Omron Corp 光学式センサ装置
JPH11506202A (ja) * 1995-06-07 1999-06-02 オプティクス エルピー 非侵入的検査及びイメージングにおける散乱を最小化し且つ組織サンプリングを改善する方法
US5847394A (en) * 1995-12-18 1998-12-08 Research Foundation Of City College Of New York Imaging of objects based upon the polarization or depolarization of light
JPH09297099A (ja) * 1996-05-07 1997-11-18 Hitachi Ltd カラー近接場光学顕微鏡
JP2002509467A (ja) * 1996-05-20 2002-03-26 ルーサド テクノロジーズ インコーポレーテッド 厚い皮膚組織を通す共焦点画像化
JPH10246697A (ja) * 1997-03-03 1998-09-14 Nikon Corp 光学的検査方法及び光学的検査装置

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005040175A (ja) * 2003-07-23 2005-02-17 Olympus Corp 生体組織の光散乱観測内視鏡装置及び観測方法
JP2007511243A (ja) * 2003-09-19 2007-05-10 ザ・ジェネラル・ホスピタル・コーポレイション 蛍光偏極撮像装置及び方法
JP2010519520A (ja) * 2007-02-20 2010-06-03 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ サンプル中の光学的な深さを評価する光学装置
JP2009300131A (ja) * 2008-06-11 2009-12-24 Tokyo Institute Of Technology 生体組織識別装置および方法
JP2010025867A (ja) * 2008-07-23 2010-02-04 Olympus Medical Systems Corp 被検体観測装置及び被検体観測方法
JP2010022717A (ja) * 2008-07-23 2010-02-04 Olympus Medical Systems Corp 被検体観測装置及び被検体観測方法
US9345385B2 (en) 2008-07-23 2016-05-24 Olympus Corporation Subject observation apparatus and subject observation method
JP2011214976A (ja) * 2010-03-31 2011-10-27 Sumitomo Chemical Co Ltd 金型検査装置、金型検査方法、防眩製品ヘイズ予測方法および防眩製品反射像鮮明度予測方法
JPWO2012057150A1 (ja) * 2010-10-29 2014-05-12 オリンパス株式会社 光学測定装置およびプローブ
US8830460B2 (en) 2010-10-29 2014-09-09 Olympus Corporation Optical measurement apparatus and probe
WO2012057150A1 (ja) * 2010-10-29 2012-05-03 オリンパス株式会社 光学測定装置およびプローブ
JP2016073687A (ja) * 2010-10-29 2016-05-12 オリンパス株式会社 光学測定装置およびプローブ
WO2013011778A1 (ja) * 2011-07-15 2013-01-24 オリンパスメディカルシステムズ株式会社 プローブ
US9107583B2 (en) 2011-07-15 2015-08-18 Olympus Medical Systems Corp. Optical measurement probe
WO2013133339A1 (ja) * 2012-03-07 2013-09-12 オリンパス株式会社 測定プローブ
JPWO2013133339A1 (ja) * 2012-03-07 2015-07-30 オリンパス株式会社 測定プローブ
US9883802B2 (en) 2012-03-07 2018-02-06 Olympus Corporation Measurement probe
JP2015514446A (ja) * 2012-03-08 2015-05-21 コーニンクレッカ フィリップス エヌ ヴェ 組織の特性を決定するための器具
US11331038B2 (en) 2012-03-08 2022-05-17 Koninklijke Philips N.V. Apparatus for determining a property of a tissue
WO2013175879A1 (ja) * 2012-05-25 2013-11-28 オリンパスメディカルシステムズ株式会社 測定プローブ
WO2014042156A1 (ja) * 2012-09-13 2014-03-20 オリンパス株式会社 測定プローブおよび生体光学測定システム
JPWO2014042156A1 (ja) * 2012-09-13 2016-08-18 オリンパス株式会社 測定プローブおよび生体光学測定システム
US10149619B2 (en) 2012-09-13 2018-12-11 Olympus Corporation Measurement probe and biological optical measurement system
KR101503272B1 (ko) 2013-07-26 2015-03-18 연세대학교 원주산학협력단 관절염 진단을 위한 다중 모드 광 영상장치

Also Published As

Publication number Publication date
NZ513118A (en) 2004-02-27
EP1153280A2 (en) 2001-11-14
WO2000043750A9 (en) 2001-08-30
CA2371782A1 (en) 2000-07-27
WO2000043750A2 (en) 2000-07-27
AU2628200A (en) 2000-08-07
KR20010110346A (ko) 2001-12-13
WO2000043750A3 (en) 2000-11-23
CN1341209A (zh) 2002-03-20
HK1041727A1 (zh) 2002-07-19

Similar Documents

Publication Publication Date Title
JP2002535645A (ja) 偏光を使用する組織の画像形成
US6404497B1 (en) Polarized light scattering spectroscopy of tissue
CN100413460C (zh) 组织病灶的表征和绘图的方法和系统
EP1021126B1 (en) Method for measuring tissue morphology
JPH11510254A (ja) 光学的微細プローベ及び材料のスペクトル分析方法
US20090326359A1 (en) Method of in vivo detection and/or diagnosis of cancer using fluorescence based dna image cytometry
US7428048B1 (en) Imaging elastic scattering spectroscopy
WO2007014213A2 (en) Tri modal spectroscopic imaging
AU2004205093A1 (en) Polarized light scattering spectroscopy of tissue
AU2004222851A1 (en) Imaging of tissue using polarized light
CN116570223A (zh) 一种与取样器镜联合使用的高光谱内窥系统
AU781659B2 (en) Method for measuring tissue morphology
HK1056108B (en) Method and system for characterization and mapping of tissue lesions

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070124

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070124

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20091113

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20100129

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100302

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20100727