CA2371782A1 - Imaging of tissue using polarized light - Google Patents
Imaging of tissue using polarized light Download PDFInfo
- Publication number
- CA2371782A1 CA2371782A1 CA002371782A CA2371782A CA2371782A1 CA 2371782 A1 CA2371782 A1 CA 2371782A1 CA 002371782 A CA002371782 A CA 002371782A CA 2371782 A CA2371782 A CA 2371782A CA 2371782 A1 CA2371782 A1 CA 2371782A1
- Authority
- CA
- Canada
- Prior art keywords
- light
- tissue
- backscattered
- fiber
- illumination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
- G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
- G02B23/2407—Optical details
- G02B23/2461—Illumination
- G02B23/2469—Illumination using optical fibres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00064—Constructional details of the endoscope body
- A61B1/00071—Insertion part of the endoscope body
- A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
- A61B1/00096—Optical elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00064—Constructional details of the endoscope body
- A61B1/00071—Insertion part of the endoscope body
- A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
- A61B1/00097—Sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00163—Optical arrangements
- A61B1/00172—Optical arrangements with means for scanning
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00163—Optical arrangements
- A61B1/00186—Optical arrangements with imaging filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
- G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
- G02B23/2407—Optical details
- G02B23/2423—Optical details of the distal end
- G02B23/243—Objectives for endoscopes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N2021/4704—Angular selective
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N2021/4792—Polarisation of scatter light
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Astronomy & Astrophysics (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Endoscopes (AREA)
- Eye Examination Apparatus (AREA)
- Instruments For Viewing The Inside Of Hollow Bodies (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11722199P | 1999-01-25 | 1999-01-25 | |
| US60/117,221 | 1999-01-25 | ||
| PCT/US2000/001764 WO2000043750A2 (en) | 1999-01-25 | 2000-01-25 | Imaging of tissue using polarized light |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2371782A1 true CA2371782A1 (en) | 2000-07-27 |
Family
ID=22371613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002371782A Abandoned CA2371782A1 (en) | 1999-01-25 | 2000-01-25 | Imaging of tissue using polarized light |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1153280A2 (enExample) |
| JP (1) | JP2002535645A (enExample) |
| KR (1) | KR20010110346A (enExample) |
| CN (1) | CN1341209A (enExample) |
| AU (1) | AU2628200A (enExample) |
| CA (1) | CA2371782A1 (enExample) |
| HK (1) | HK1041727A1 (enExample) |
| NZ (1) | NZ513118A (enExample) |
| WO (1) | WO2000043750A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001294997A1 (en) * | 2000-08-14 | 2002-03-13 | Oralscan Laboratories, Inc. | Detection of epithelial dysplasia |
| IL157158A0 (en) * | 2001-03-02 | 2004-02-08 | Spectrx Inc | System and method for determining tissue characteristics |
| US7404929B2 (en) | 2002-01-18 | 2008-07-29 | Newton Laboratories, Inc. | Spectroscopic diagnostic methods and system based on scattering of polarized light |
| EP1472517A1 (en) | 2002-01-18 | 2004-11-03 | Newton Laboratories, Inc. | Spectroscopic diagnostic methods and system |
| AU2002337504A1 (en) * | 2002-06-08 | 2003-12-22 | Kwon Soo Ha | Method for protein chip analysis by using surface plasmon resonance spectroscopic imaging technology |
| CN102866116B (zh) * | 2003-06-04 | 2015-08-19 | 广东永士达医疗科技有限公司 | 利用光的传播模式测量物质中的光学不均匀性和其他属性 |
| JP4535697B2 (ja) * | 2003-07-23 | 2010-09-01 | オリンパス株式会社 | 生体組織の光散乱観測内視鏡装置 |
| JP4700001B2 (ja) * | 2003-09-19 | 2011-06-15 | ザ ジェネラル ホスピタル コーポレイション | 蛍光偏極撮像方法 |
| CN100443041C (zh) * | 2004-05-26 | 2008-12-17 | 吴冈 | 具有测量功能的内窥镜系统及其测量方法 |
| US20070167835A1 (en) * | 2005-07-25 | 2007-07-19 | Massachusetts Institute Of Technology | Tri modal spectroscopic imaging |
| CN101326428B (zh) * | 2005-10-11 | 2011-05-18 | 杜克大学 | 用于内窥镜的角度分辨低相干干涉测量的系统和方法 |
| CN101616627B (zh) * | 2007-02-20 | 2011-08-03 | 皇家飞利浦电子股份有限公司 | 用于评估样本中的光学深度的光学设备 |
| CN101641043B (zh) * | 2007-03-12 | 2012-01-11 | 皇家飞利浦电子股份有限公司 | 用于复合上皮早期癌症的诊断和分期的系统 |
| CN100506150C (zh) * | 2007-04-28 | 2009-07-01 | 马剑文 | 活体组织光学检测装置及其工作方法 |
| DE202008009859U1 (de) * | 2007-12-21 | 2009-03-05 | Berthold Technologies Gmbh & Co. Kg | Vorrichtung zur wahlweisen Messung von insbesondere Lumineszenz- und/oder Fluoreszenzstrahlung |
| JP4575474B2 (ja) * | 2008-06-11 | 2010-11-04 | 国立大学法人東京工業大学 | 生体組織識別装置および方法 |
| KR101109968B1 (ko) | 2008-07-23 | 2012-02-17 | 올림푸스 메디칼 시스템즈 가부시키가이샤 | 피검체 관측 장치 및 피검체 관측 방법 |
| JP2010025867A (ja) * | 2008-07-23 | 2010-02-04 | Olympus Medical Systems Corp | 被検体観測装置及び被検体観測方法 |
| JP5191831B2 (ja) * | 2008-07-23 | 2013-05-08 | オリンパスメディカルシステムズ株式会社 | 被検体観測装置及び被検体観測装置の作動方法 |
| EP2373979A1 (en) * | 2008-12-02 | 2011-10-12 | Koninklijke Philips Electronics N.V. | Sensor device for detecting target particles by frustrated total internal reflection |
| JP5532479B2 (ja) * | 2010-03-31 | 2014-06-25 | 住友化学株式会社 | 金型検査方法、防眩製品ヘイズ予測方法および防眩製品反射像鮮明度予測方法 |
| JPWO2012057150A1 (ja) | 2010-10-29 | 2014-05-12 | オリンパス株式会社 | 光学測定装置およびプローブ |
| WO2013011778A1 (ja) * | 2011-07-15 | 2013-01-24 | オリンパスメディカルシステムズ株式会社 | プローブ |
| JP6028015B2 (ja) * | 2012-03-07 | 2016-11-16 | オリンパス株式会社 | 測定プローブ |
| CN104159500B (zh) * | 2012-03-08 | 2018-08-07 | 皇家飞利浦有限公司 | 用于确定组织的特性的装置 |
| JP6398093B2 (ja) | 2012-04-13 | 2018-10-03 | ベイカー ハート アンド ダイアベーツ インスティテュート | アテローム斑の検出 |
| WO2013175879A1 (ja) * | 2012-05-25 | 2013-11-28 | オリンパスメディカルシステムズ株式会社 | 測定プローブ |
| EP2896350A4 (en) * | 2012-09-13 | 2016-06-15 | Olympus Corp | MEASURING PROBE AND BIOLOGICAL OPTICAL MEASURING SYSTEM |
| DE102012221527A1 (de) * | 2012-11-26 | 2014-06-12 | Heine Optotechnik Gmbh & Co Kg | Optisches Diagnoseinstrument |
| EP2989441B1 (en) * | 2013-04-21 | 2019-01-02 | Mobileodt Ltd | A polarized light imaging apparatus and associated method for separating light from a surface of a sample and its deeper layers |
| CN104280350B (zh) * | 2013-07-03 | 2018-06-01 | 庞小峰 | 一种特殊锐化的癌症早期诊断和治疗效果检查的装置 |
| KR101503272B1 (ko) | 2013-07-26 | 2015-03-18 | 연세대학교 원주산학협력단 | 관절염 진단을 위한 다중 모드 광 영상장치 |
| CN106725250A (zh) * | 2017-01-09 | 2017-05-31 | 清华大学深圳研究生院 | 一种头端调制的内窥偏振成像系统及测量方法 |
| KR102881023B1 (ko) | 2017-08-31 | 2025-11-04 | 메탈렌츠 인코포레이티드 | 투과성 메타표면 렌즈 통합 |
| CN118707744A (zh) | 2018-07-02 | 2024-09-27 | 梅特兰兹股份有限公司 | 用于激光散斑减少的超表面 |
| US11978752B2 (en) | 2019-07-26 | 2024-05-07 | Metalenz, Inc. | Aperture-metasurface and hybrid refractive-metasurface imaging systems |
| CN113075097A (zh) * | 2021-03-22 | 2021-07-06 | 厦门理工学院 | 一种基于散射光偏振检测的粒径测量方法、装置及设备 |
| EP4500265A2 (en) | 2022-03-31 | 2025-02-05 | Metalenz, Inc. | Polarization sorting metasurface microlens array device |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61129554A (ja) * | 1984-11-28 | 1986-06-17 | Nippon Paint Co Ltd | 散乱光測定装置 |
| GB8701521D0 (en) * | 1987-01-23 | 1993-12-01 | British Aerospace | Multi-parameter imaging polarimeter |
| US4953978A (en) * | 1989-03-03 | 1990-09-04 | Coulter Electronics Of New England, Inc. | Particle size analysis utilizing polarization intensity differential scattering |
| WO1992014812A1 (en) * | 1991-02-22 | 1992-09-03 | Coulter Corporation | Method and apparatus for screening microscopic cells utilizing polarized light scatter techniques |
| JPH0611439A (ja) * | 1992-06-29 | 1994-01-21 | Olympus Optical Co Ltd | 生体組織の酸素代謝測定装置 |
| US5672875A (en) * | 1992-07-15 | 1997-09-30 | Optix Lp | Methods of minimizing scattering and improving tissue sampling in non-invasive testing and imaging |
| US5421339A (en) * | 1993-05-12 | 1995-06-06 | Board Of Regents, The University Of Texas System | Diagnosis of dysplasia using laser induced fluoroescence |
| JP3451515B2 (ja) * | 1995-04-06 | 2003-09-29 | オムロン株式会社 | 光学式センサ装置 |
| US5788639A (en) * | 1995-07-13 | 1998-08-04 | Lucid Technologies, Inc. | Confocal imaging through thick dermal tissue |
| US5719399A (en) * | 1995-12-18 | 1998-02-17 | The Research Foundation Of City College Of New York | Imaging and characterization of tissue based upon the preservation of polarized light transmitted therethrough |
| JPH09297099A (ja) * | 1996-05-07 | 1997-11-18 | Hitachi Ltd | カラー近接場光学顕微鏡 |
| JPH10246697A (ja) * | 1997-03-03 | 1998-09-14 | Nikon Corp | 光学的検査方法及び光学的検査装置 |
-
2000
- 2000-01-25 CA CA002371782A patent/CA2371782A1/en not_active Abandoned
- 2000-01-25 CN CN00804259A patent/CN1341209A/zh active Pending
- 2000-01-25 KR KR1020017009360A patent/KR20010110346A/ko not_active Ceased
- 2000-01-25 EP EP00904542A patent/EP1153280A2/en not_active Withdrawn
- 2000-01-25 WO PCT/US2000/001764 patent/WO2000043750A2/en not_active Ceased
- 2000-01-25 JP JP2000595125A patent/JP2002535645A/ja active Pending
- 2000-01-25 NZ NZ513118A patent/NZ513118A/xx unknown
- 2000-01-25 AU AU26282/00A patent/AU2628200A/en not_active Abandoned
- 2000-01-25 HK HK02103359.7A patent/HK1041727A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ513118A (en) | 2004-02-27 |
| EP1153280A2 (en) | 2001-11-14 |
| WO2000043750A9 (en) | 2001-08-30 |
| JP2002535645A (ja) | 2002-10-22 |
| WO2000043750A2 (en) | 2000-07-27 |
| AU2628200A (en) | 2000-08-07 |
| KR20010110346A (ko) | 2001-12-13 |
| WO2000043750A3 (en) | 2000-11-23 |
| CN1341209A (zh) | 2002-03-20 |
| HK1041727A1 (zh) | 2002-07-19 |
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