KR20010012374A - 지속 효과를 갖는 서방성 겔 - Google Patents

지속 효과를 갖는 서방성 겔 Download PDF

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Publication number
KR20010012374A
KR20010012374A KR1019997010326A KR19997010326A KR20010012374A KR 20010012374 A KR20010012374 A KR 20010012374A KR 1019997010326 A KR1019997010326 A KR 1019997010326A KR 19997010326 A KR19997010326 A KR 19997010326A KR 20010012374 A KR20010012374 A KR 20010012374A
Authority
KR
South Korea
Prior art keywords
composition
biologically active
protein
alginate
active agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1019997010326A
Other languages
English (en)
Korean (ko)
Inventor
골든버그메릴시머
빅맨앨리스씨
구지안화
Original Assignee
스티븐 엠. 오드레
암젠 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 스티븐 엠. 오드레, 암젠 인코포레이티드 filed Critical 스티븐 엠. 오드레
Publication of KR20010012374A publication Critical patent/KR20010012374A/ko
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
KR1019997010326A 1997-05-16 1998-05-18 지속 효과를 갖는 서방성 겔 Ceased KR20010012374A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85797397A 1997-05-16 1997-05-16
US?08/857,973? 1997-05-16
US91290297A 1997-08-15 1997-08-15
US?08/912,902? 1997-08-15

Publications (1)

Publication Number Publication Date
KR20010012374A true KR20010012374A (ko) 2001-02-15

Family

ID=27127437

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019997010326A Ceased KR20010012374A (ko) 1997-05-16 1998-05-18 지속 효과를 갖는 서방성 겔

Country Status (18)

Country Link
EP (1) EP0981374B1 (https=)
JP (1) JP2001525826A (https=)
KR (1) KR20010012374A (https=)
AU (1) AU7491898A (https=)
BG (1) BG64860B1 (https=)
BR (1) BR9809117A (https=)
CA (1) CA2289196C (https=)
CZ (1) CZ299180B6 (https=)
DE (1) DE69838750T2 (https=)
EA (1) EA199901013A1 (https=)
ES (1) ES2294814T3 (https=)
HU (1) HUP0003393A3 (https=)
IL (1) IL132814A0 (https=)
NO (1) NO995591D0 (https=)
PL (1) PL199565B1 (https=)
SK (1) SK286437B6 (https=)
WO (1) WO1998051348A2 (https=)
YU (1) YU58599A (https=)

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* Cited by examiner, † Cited by third party
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AU2003200609B2 (en) * 1998-05-18 2006-02-23 Amgen Inc. Biodegradable sustained-release alginate gels
US6432449B1 (en) * 1998-05-18 2002-08-13 Amgen Inc. Biodegradable sustained-release alginate gels
JP2000256216A (ja) * 1999-03-04 2000-09-19 Meiji Milk Prod Co Ltd ゲル組成物
US7651703B2 (en) 1999-10-15 2010-01-26 Genentech, Inc. Injection vehicle for polymer-based formulations
US7582311B1 (en) 1999-10-15 2009-09-01 Genentech, Inc. Injection vehicle for polymer-based formulations
EP1233751A1 (en) * 1999-11-29 2002-08-28 ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, Inc. Sustained percutaneous delivery of a biologically active substance
FR2823119B1 (fr) * 2001-04-05 2004-02-20 Seppic Sa Adjuvant d'immunite contenant un cation metallique complexe et vaccin le contenant
CN1703198A (zh) * 2002-10-25 2005-11-30 辉瑞产品公司 呈混悬剂形式的芳基杂环活性物质的贮库制剂
CA2621365C (en) * 2005-05-23 2012-09-04 Natural Alternatives International Compositions and methods for the sustained release of beta-alanine
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
JP5107585B2 (ja) * 2007-01-29 2012-12-26 株式会社 メドレックス 低温充填ゼリー組成物とその製造方法
EP1985286A1 (en) * 2007-04-24 2008-10-29 Biocompatibles UK Limited Microspheres for treatment of brain tumours
JP5996544B2 (ja) 2010-10-15 2016-09-21 クリアサイド・バイオメディカル・インコーポレーテッドＣｌｅａｒｓｉｄｅ Ｂｉｏｍｅｄｉｃａｌ Ｉｎｃｏｒｐｏｒａｔｅｄ 眼球アクセス用装置
MX373894B (es) 2012-11-08 2020-07-09 Clearside Biomedical Inc Métodos y dispositivos para el tratamiento de trastornos oculares en sujetos humanos.
BR112015027762A2 (pt) 2013-05-03 2017-08-29 Clearside Biomedical Inc Aparelho e métodos para injeção ocular
US10010447B2 (en) 2013-12-18 2018-07-03 Novartis Ag Systems and methods for subretinal delivery of therapeutic agents
EP3157598A4 (en) 2014-06-20 2018-05-16 Clearside Biomedical, Inc. Variable diameter cannula and methods for controlling insertion depth for medicament delivery
US10390901B2 (en) 2016-02-10 2019-08-27 Clearside Biomedical, Inc. Ocular injection kit, packaging, and methods of use
EP3452165A1 (en) 2016-05-02 2019-03-13 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
IL305537B2 (en) 2016-08-12 2025-02-01 Clearside Biomedical Inc Devices and methods for adjusting the insertion depth of a needle for administering a drug
US12090294B2 (en) 2017-05-02 2024-09-17 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
CN112367841B (zh) * 2018-06-04 2023-06-09 斯博姆维透公司 用于制备水凝胶的功能化试剂盒
US20210369875A1 (en) * 2018-11-06 2021-12-02 National Cancer Center Alginic acid-based injectable hydrogel system
WO2021067076A1 (en) * 2019-10-01 2021-04-08 Brillian Pharma Inc. Methods for treating or preventing obesity and body weight management
WO2021193981A1 (ja) * 2020-03-26 2021-09-30 国立大学法人大阪大学 三次元（３ｄ）組織培養用のサポーティングバス
CN114533653B (zh) * 2020-11-26 2023-12-22 上海凯茂生物医药有限公司 一种人促红素杂合Fc融合蛋白相变型制剂及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5416979B2 (https=) * 1972-01-08 1979-06-26
US4241099A (en) * 1979-02-26 1980-12-23 Tiemstra Peter J Pectin formulations, products and methods having delayed-action acidulants
US4690682A (en) * 1983-04-15 1987-09-01 Damon Biotech, Inc. Sustained release
US4789516A (en) * 1983-04-15 1988-12-06 Damon Biotech, Inc Production of sustained released system
US4744933A (en) * 1984-02-15 1988-05-17 Massachusetts Institute Of Technology Process for encapsulation and encapsulated active material system
CA1215922A (en) * 1984-05-25 1986-12-30 Connaught Laboratories Limited Microencapsulation of living tissue and cells
JPS645460A (en) * 1987-06-29 1989-01-10 Sanei Kagaku Kogyo Kk Production of delaying gelatinous material
JPH0794583B2 (ja) * 1989-12-15 1995-10-11 株式会社大塚製薬工場 高含水高分子ゲル
IT1245383B (it) * 1991-03-28 1994-09-20 Eniricerche Spa Composizione acquosa gelificabile avente tempo di gelificazione ritardato
US5711968A (en) * 1994-07-25 1998-01-27 Alkermes Controlled Therapeutics, Inc. Composition and method for the controlled release of metal cation-stabilized interferon
KR960006730B1 (ko) * 1993-02-11 1996-05-23 재단법인한국화학연구소 에멀젼 네트웍(emulsion network)을 이용한 약물의 피부 전달체계
GB9708773D0 (en) * 1997-04-30 1997-06-25 Reckitt & Colmann Prod Ltd Organic compositions

Also Published As

Publication number Publication date
NO995591L (no) 1999-11-15
CA2289196C (en) 2007-08-07
JP2001525826A (ja) 2001-12-11
CZ396399A3 (cs) 2000-04-12
DE69838750D1 (de) 2008-01-03
IL132814A0 (en) 2001-03-19
HUP0003393A3 (en) 2001-03-28
BR9809117A (pt) 2000-08-01
WO1998051348A3 (en) 1999-02-18
EA199901013A1 (ru) 2000-06-26
BG103914A (en) 2000-07-31
DE69838750T2 (de) 2008-10-30
YU58599A (sh) 2000-12-28
ES2294814T3 (es) 2008-04-01
BG64860B1 (bg) 2006-07-31
SK286437B6 (sk) 2008-10-07
NO995591D0 (no) 1999-11-15
SK154399A3 (en) 2000-07-11
HUP0003393A2 (hu) 2001-02-28
EP0981374B1 (en) 2007-11-21
PL199565B1 (pl) 2008-10-31
PL336887A1 (en) 2000-07-17
EP0981374A2 (en) 2000-03-01
AU7491898A (en) 1998-12-08
CZ299180B6 (cs) 2008-05-14
WO1998051348A2 (en) 1998-11-19
CA2289196A1 (en) 1998-11-19

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 19991108

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20030519

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20050228

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20050930

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20050228

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I