KR102824235B1 - 골수증식성 장애를 치료하기 위한 방법 - Google Patents
골수증식성 장애를 치료하기 위한 방법 Download PDFInfo
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- KR102824235B1 KR102824235B1 KR1020187006105A KR20187006105A KR102824235B1 KR 102824235 B1 KR102824235 B1 KR 102824235B1 KR 1020187006105 A KR1020187006105 A KR 1020187006105A KR 20187006105 A KR20187006105 A KR 20187006105A KR 102824235 B1 KR102824235 B1 KR 102824235B1
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- myelofibrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- A—HUMAN NECESSITIES
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- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Nutrition Science (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Ophthalmology & Optometry (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020257020329A KR20250093593A (ko) | 2015-08-04 | 2016-08-04 | 골수증식성 장애를 치료하기 위한 방법 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562201058P | 2015-08-04 | 2015-08-04 | |
| US62/201,058 | 2015-08-04 | ||
| US201562263603P | 2015-12-04 | 2015-12-04 | |
| US62/263,603 | 2015-12-04 | ||
| PCT/US2016/045631 WO2017024171A1 (en) | 2015-08-04 | 2016-08-04 | Methods for treating myeloproliferative disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020257020329A Division KR20250093593A (ko) | 2015-08-04 | 2016-08-04 | 골수증식성 장애를 치료하기 위한 방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20180035884A KR20180035884A (ko) | 2018-04-06 |
| KR102824235B1 true KR102824235B1 (ko) | 2025-06-25 |
Family
ID=57943723
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020257020329A Pending KR20250093593A (ko) | 2015-08-04 | 2016-08-04 | 골수증식성 장애를 치료하기 위한 방법 |
| KR1020187006105A Active KR102824235B1 (ko) | 2015-08-04 | 2016-08-04 | 골수증식성 장애를 치료하기 위한 방법 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020257020329A Pending KR20250093593A (ko) | 2015-08-04 | 2016-08-04 | 골수증식성 장애를 치료하기 위한 방법 |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US9884900B2 (enExample) |
| EP (2) | EP3331550B1 (enExample) |
| JP (3) | JP7320350B2 (enExample) |
| KR (2) | KR20250093593A (enExample) |
| CN (2) | CN116327952A (enExample) |
| AU (2) | AU2016301380B2 (enExample) |
| CA (1) | CA2994413A1 (enExample) |
| HK (1) | HK1256638A1 (enExample) |
| WO (1) | WO2017024171A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8216997B2 (en) | 2008-08-14 | 2012-07-10 | Acceleron Pharma, Inc. | Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators |
| MX366336B (es) | 2012-11-02 | 2019-07-05 | Celgene Corp | Antagonistas de activina - actrii y usos para el tratar trastornos oseos y otros. |
| HK1225740A1 (zh) | 2013-08-22 | 2017-09-15 | Acceleron Pharma Inc. | TGF-β受体II型变体及其用途 |
| CN120919282A (zh) | 2013-11-21 | 2025-11-11 | 布里格姆及妇女医院股份有限公司 | 用于治疗肺高压的组合物和方法 |
| FI3227675T3 (fi) | 2014-12-03 | 2023-05-25 | Celgene Corp | Aktiviini-actrii-antagonisteja ja niiden käyttöjä myelodysplastisen oireyhtymän hoitamiseksi |
| MA41119A (fr) | 2014-12-03 | 2017-10-10 | Acceleron Pharma Inc | Méthodes de traitement de syndromes myélodysplasiques et d'anémie sidéroblastique |
| CN116327952A (zh) | 2015-08-04 | 2023-06-27 | 阿塞勒隆制药公司 | 用于治疗骨髓增生性病症的方法 |
| MX2019001043A (es) | 2016-07-27 | 2019-09-26 | Acceleron Pharma Inc | Metodos y composiciones para el tratamiento de la mielofibrosis. |
| EP3628049B1 (en) | 2017-05-04 | 2023-05-10 | Acceleron Pharma Inc. | Tgf-beta receptor type ii fusion proteins and uses thereof |
| CA3061791A1 (en) * | 2017-05-12 | 2019-10-29 | Jiangsu Hengrui Medicine Co., Ltd. | Fusion protein containing tgf-.beta. receptor and medicinal uses thereof |
| HUE068733T2 (hu) * | 2017-06-14 | 2025-01-28 | Celgene Corp | Eljárások mieloproliferatív neoplazma-asszociált mielofibrózis anémia kezelésére |
| AU2019231791B2 (en) | 2018-03-09 | 2022-08-11 | Agenus Inc. | Anti-CD73 antibodies and methods of use thereof |
| US20210113524A1 (en) * | 2018-05-31 | 2021-04-22 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Methods of treating myeloproliferative disorders |
| WO2020068755A1 (en) * | 2018-09-25 | 2020-04-02 | Impact Biomedicines, Inc. | Methods of treating myeloproliferative disorders |
| WO2021021528A1 (en) * | 2019-07-26 | 2021-02-04 | Board Of Trustees Of Michigan State University | Methods of preventing or treating fatty degeneration of skeletal muscle |
| KR20220088699A (ko) | 2019-09-27 | 2022-06-28 | 디스크 메디슨, 인크. | 골수섬유증 및 관련 상태의 치료 방법 |
| US20220347182A1 (en) * | 2019-10-02 | 2022-11-03 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for the treatment of osteoarthritis |
| US20240226235A1 (en) * | 2019-11-05 | 2024-07-11 | Acceleron Pharma Inc. | Treatments for systemic sclerosis |
| US12441707B2 (en) | 2019-12-30 | 2025-10-14 | Tyra Biosciences, Inc. | Indazole compounds |
| JP2023528223A (ja) | 2020-05-13 | 2023-07-04 | ディスク・メディシン・インコーポレイテッド | 骨髄線維症を処置するための抗ヘモジュベリン(hjv)抗体 |
| CN116635036B (zh) * | 2020-12-18 | 2025-06-17 | 努瓦米德股份有限公司 | 烟酰胺单核苷酸衍生物及其在治疗和预防红细胞病症中的用途 |
| KR102794148B1 (ko) * | 2021-08-18 | 2025-04-11 | 주식회사 삼양홀딩스 | 룩소리티닙의 경구용 정제 조성물 및 이의 제조 방법 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015027082A1 (en) * | 2013-08-22 | 2015-02-26 | Acceleron Pharma, Inc. | Tgf-beta receptor type ii variants and uses thereof |
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| US20220332778A1 (en) | 2022-10-20 |
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