IL98569A0 - Pharmaceutical compositions containing tgf-b and antagonists thereof for modulating blood pressure - Google Patents

Pharmaceutical compositions containing tgf-b and antagonists thereof for modulating blood pressure

Info

Publication number
IL98569A0
IL98569A0 IL98569A IL9856991A IL98569A0 IL 98569 A0 IL98569 A0 IL 98569A0 IL 98569 A IL98569 A IL 98569A IL 9856991 A IL9856991 A IL 9856991A IL 98569 A0 IL98569 A0 IL 98569A0
Authority
IL
Israel
Prior art keywords
antagonists
pharmaceutical compositions
blood pressure
compositions containing
containing tgf
Prior art date
Application number
IL98569A
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of IL98569A0 publication Critical patent/IL98569A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL98569A 1990-06-20 1991-06-20 Pharmaceutical compositions containing tgf-b and antagonists thereof for modulating blood pressure IL98569A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54122190A 1990-06-20 1990-06-20

Publications (1)

Publication Number Publication Date
IL98569A0 true IL98569A0 (en) 1992-07-15

Family

ID=24158683

Family Applications (1)

Application Number Title Priority Date Filing Date
IL98569A IL98569A0 (en) 1990-06-20 1991-06-20 Pharmaceutical compositions containing tgf-b and antagonists thereof for modulating blood pressure

Country Status (4)

Country Link
IL (1) IL98569A0 (en)
TW (1) TW205005B (en)
WO (1) WO1991019513A1 (en)
ZA (1) ZA914750B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571714A (en) 1988-12-22 1996-11-05 Celtrix Pharmaceuticals, Inc. Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use
US5280109A (en) * 1992-01-27 1994-01-18 Ludwig Institute For Cancer Research Isolated, large latent complexes of TGF-β2 and TGF-β3, and new binding protein for latent form TGF-β1, TGF-β2 and TGF-β3 LTBP-2
JPH08504763A (en) * 1992-10-29 1996-05-21 セルトリックス ファーマシューティカルズ，インコーポレイテッド Use of TGF-β receptor fragment as a therapeutic agent
EP0684828A4 (en) * 1993-02-19 1996-08-07 Celtrix Pharma EXPANSION OF STEM CELLS IN LONG TERM BONE MARROW CULTURES BY NEUTRALIZATION OF TGF--g(b).
EP0828849B1 (en) * 1995-06-02 2006-10-25 Gilead Sciences, Inc. High-affinity oligonucleotide ligands to pdgf
DE19613691A1 (en) 1996-04-05 1997-10-09 Boehringer Ingelheim Int Medicines for the treatment of tumor diseases
AU2001272100A1 (en) * 2000-03-09 2001-09-17 Genzyme Corporation Use of tgf-beta antagonists to treat or to prevent loss of renal function
US9974759B2 (en) 2013-05-31 2018-05-22 Indiana University Research And Technology Corporation Beta 2 adrenoceptor antagonists for treating orthostatic hypotension
AU2014308751B2 (en) 2013-08-22 2020-03-05 Acceleron Pharma, Inc. TGF-beta receptor type II variants and uses thereof
EP3331550B1 (en) 2015-08-04 2022-11-02 Acceleron Pharma Inc. Composition for treating myeloproliferative disorders
BR112019023071A2 (en) 2017-05-04 2020-06-09 Acceleron Pharma Inc type ii tgf-beta receptor fusion proteins and use thereof

Also Published As

Publication number Publication date
TW205005B (en) 1993-05-01
ZA914750B (en) 1992-03-25
WO1991019513A1 (en) 1991-12-26

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