KR102736980B1 - 면역 신호전달 초래 및/또는 창자 장벽 기능에 영향 및/또는 대사 상태를 조절하기 위한 폴리펩티드의 용도 - Google Patents

면역 신호전달 초래 및/또는 창자 장벽 기능에 영향 및/또는 대사 상태를 조절하기 위한 폴리펩티드의 용도 Download PDF

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KR102736980B1
KR102736980B1 KR1020177035003A KR20177035003A KR102736980B1 KR 102736980 B1 KR102736980 B1 KR 102736980B1 KR 1020177035003 A KR1020177035003 A KR 1020177035003A KR 20177035003 A KR20177035003 A KR 20177035003A KR 102736980 B1 KR102736980 B1 KR 102736980B1
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polypeptide
acid sequence
nucleic acid
cholesterol
amino acid
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KR20180011130A (ko
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클라라 벨저
보스 빌럼 마인데르트 데
패트리스 다니엘 카니
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바게닝겐 유니버시테이트
위니베르시트카솔리끄드루뱅
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020177035003A 2015-05-06 2016-05-04 면역 신호전달 초래 및/또는 창자 장벽 기능에 영향 및/또는 대사 상태를 조절하기 위한 폴리펩티드의 용도 Active KR102736980B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15166598.1 2015-05-06
EP15166598 2015-05-06
PCT/EP2016/060033 WO2016177797A1 (en) 2015-05-06 2016-05-04 Use of a polypeptide for effecting immune signalling and/or affecting intestinal barrier function and/or modulating metabolic status

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KR20180011130A KR20180011130A (ko) 2018-01-31
KR102736980B1 true KR102736980B1 (ko) 2024-12-02

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US (2) US10738089B2 (https=)
EP (1) EP3292135B1 (https=)
JP (1) JP6894382B2 (https=)
KR (1) KR102736980B1 (https=)
CN (1) CN107980043B (https=)
AU (2) AU2016257315A1 (https=)
DK (1) DK3292135T3 (https=)
EA (1) EA201700507A1 (https=)
ES (1) ES2934138T3 (https=)
HK (1) HK1252412A1 (https=)
IL (1) IL255405B (https=)
MX (1) MX390092B (https=)
PL (1) PL3292135T3 (https=)
WO (1) WO2016177797A1 (https=)

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KR102197180B1 (ko) * 2018-10-11 2020-12-31 주식회사 고바이오랩 아커만시아 뮤시니필라 균주 및 이를 포함하는 식욕 억제 및 대사성 질환 예방, 개선, 완화 및 치료용 조성물
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CN111690044B (zh) * 2020-05-06 2022-03-01 中南大学湘雅二医院 Amuc1100蛋白的用途
CN115996943A (zh) * 2020-07-01 2023-04-21 瓦赫宁根大学 用于影响免疫信号传导和/或影响肠屏障功能和/或调节代谢状态的Amuc-1100多肽变体
WO2022098051A1 (ko) * 2020-11-05 2022-05-12 한국생명공학연구원 항염 및 조직 재생작용을 갖는 신규 펩타이드
CN113413466B (zh) * 2020-12-15 2022-08-19 和度生物医药(上海)有限公司 用于治疗癌症的amuc_1100和免疫检查点调节剂的组合疗法
CN115364198A (zh) * 2022-08-23 2022-11-22 广州康泽医疗科技有限公司 膜蛋白Amuc_1100在促进前脂肪细胞脂解和棕色化中的应用
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Publication number Publication date
US11466057B2 (en) 2022-10-11
WO2016177797A1 (en) 2016-11-10
HK1252412A1 (zh) 2019-05-24
EP3292135B1 (en) 2022-09-21
IL255405B (en) 2022-01-01
MX390092B (es) 2025-03-11
NZ737765A (en) 2024-08-30
IL255405A0 (en) 2017-12-31
KR20180011130A (ko) 2018-01-31
PL3292135T3 (pl) 2023-01-02
EP3292135A1 (en) 2018-03-14
AU2016257315A1 (en) 2017-11-23
JP6894382B2 (ja) 2021-06-30
AU2020267210A1 (en) 2020-12-17
AU2020267210B2 (en) 2023-10-12
US20210147489A1 (en) 2021-05-20
JP2018515502A (ja) 2018-06-14
CN107980043A (zh) 2018-05-01
CA2984985A1 (en) 2016-11-10
US10738089B2 (en) 2020-08-11
MX2017014111A (es) 2018-02-26
BR112017023751A2 (pt) 2018-07-31
DK3292135T3 (da) 2022-10-31
EA201700507A1 (ru) 2018-05-31
US20180265554A1 (en) 2018-09-20
ES2934138T3 (es) 2023-02-17
CN107980043B (zh) 2021-09-24

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