KR102669966B1 - 브루톤 티로신 키나제 억제제로서 작용하는 폴리플루오로화 화합물 - Google Patents
브루톤 티로신 키나제 억제제로서 작용하는 폴리플루오로화 화합물 Download PDFInfo
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- KR102669966B1 KR102669966B1 KR1020237032203A KR20237032203A KR102669966B1 KR 102669966 B1 KR102669966 B1 KR 102669966B1 KR 1020237032203 A KR1020237032203 A KR 1020237032203A KR 20237032203 A KR20237032203 A KR 20237032203A KR 102669966 B1 KR102669966 B1 KR 102669966B1
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- C07C303/38—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reaction of ammonia or amines with sulfonic acids, or with esters, anhydrides, or halides thereof
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410175783.7A CN105017256A (zh) | 2014-04-29 | 2014-04-29 | 多氟化合物作为布鲁顿酪氨酸激酶抑制剂 |
| CN201410175783.7 | 2014-04-29 | ||
| PCT/CN2015/000290 WO2015165279A1 (zh) | 2014-04-29 | 2015-04-27 | 多氟化合物作为布鲁顿酪氨酸激酶抑制剂 |
| KR1020167028059A KR20160144378A (ko) | 2014-04-29 | 2015-04-27 | 브루톤 티로신 키나제 억제제로서 작용하는 폴리플루오로화 화합물 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167028059A Division KR20160144378A (ko) | 2014-04-29 | 2015-04-27 | 브루톤 티로신 키나제 억제제로서 작용하는 폴리플루오로화 화합물 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20230137499A KR20230137499A (ko) | 2023-10-04 |
| KR102669966B1 true KR102669966B1 (ko) | 2024-05-27 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020237032203A Active KR102669966B1 (ko) | 2014-04-29 | 2015-04-27 | 브루톤 티로신 키나제 억제제로서 작용하는 폴리플루오로화 화합물 |
| KR1020167028059A Ceased KR20160144378A (ko) | 2014-04-29 | 2015-04-27 | 브루톤 티로신 키나제 억제제로서 작용하는 폴리플루오로화 화합물 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167028059A Ceased KR20160144378A (ko) | 2014-04-29 | 2015-04-27 | 브루톤 티로신 키나제 억제제로서 작용하는 폴리플루오로화 화합물 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US9532990B2 (enExample) |
| EP (1) | EP3138842B1 (enExample) |
| JP (2) | JP6670756B2 (enExample) |
| KR (2) | KR102669966B1 (enExample) |
| CN (3) | CN105017256A (enExample) |
| AU (1) | AU2015252654C1 (enExample) |
| BR (1) | BR112016025132A2 (enExample) |
| CA (1) | CA2947338C (enExample) |
| EA (2) | EA037227B1 (enExample) |
| ES (1) | ES2857251T3 (enExample) |
| IL (1) | IL248546B (enExample) |
| MX (2) | MX387487B (enExample) |
| WO (1) | WO2015165279A1 (enExample) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101974254B1 (ko) | 2013-07-18 | 2019-04-30 | 다이호야쿠힌고교 가부시키가이샤 | Fgfr 저해제의 간헐 투여용 항종양제 |
| US10124003B2 (en) | 2013-07-18 | 2018-11-13 | Taiho Pharmaceutical Co., Ltd. | Therapeutic agent for FGFR inhibitor-resistant cancer |
| CN105017256A (zh) * | 2014-04-29 | 2015-11-04 | 浙江导明医药科技有限公司 | 多氟化合物作为布鲁顿酪氨酸激酶抑制剂 |
| US10196397B2 (en) * | 2014-11-19 | 2019-02-05 | Sun Pharmaceutical Industries Limited | Process for the preparation of ibrutinib |
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