KR102667385B1 - Ppar 효능제, 화합물, 제약 조성물, 및 그의 사용 방법 - Google Patents
Ppar 효능제, 화합물, 제약 조성물, 및 그의 사용 방법 Download PDFInfo
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- KR102667385B1 KR102667385B1 KR1020187012860A KR20187012860A KR102667385B1 KR 102667385 B1 KR102667385 B1 KR 102667385B1 KR 1020187012860 A KR1020187012860 A KR 1020187012860A KR 20187012860 A KR20187012860 A KR 20187012860A KR 102667385 B1 KR102667385 B1 KR 102667385B1
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- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
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- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
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| EP3770146B1 (en) * | 2015-10-07 | 2024-07-24 | Astellas Engineered Small Molecules US, Incorporated | Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof |
| CN109071459B (zh) | 2016-04-13 | 2022-08-16 | 米托布里奇公司 | Ppar激动剂、化合物、药物组合物以及它们的使用方法 |
| MA46459B1 (fr) * | 2016-10-05 | 2021-03-31 | Mitobridge Inc | Méthode de traitement de lésions rénales aiguës |
| KR20190057129A (ko) * | 2016-10-05 | 2019-05-27 | 미토브리지, 인크. | Ppar 작용제 화합물의 결정형 및 염 형태 |
| WO2021046081A1 (en) * | 2019-09-05 | 2021-03-11 | Rush University Medical Center | Methods and compositions for treatment of demyelinating disorders |
| US11634387B2 (en) | 2019-09-26 | 2023-04-25 | Abionyx Pharma Sa | Compounds useful for treating liver diseases |
| WO2022189856A1 (en) | 2021-03-08 | 2022-09-15 | Abionyx Pharma Sa | Compounds useful for treating liver diseases |
| CA3221429A1 (en) | 2021-06-02 | 2022-12-08 | Astellas Pharma Inc. | Methods of use of ppar agonist compounds and pharmaceutical compositions thereof |
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| EP4230196A1 (en) | 2022-02-21 | 2023-08-23 | Som Innovation Biotech, S.A. | Compounds for use in the treatment of dystrophinopathies |
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| WO2014165827A1 (en) | 2013-04-05 | 2014-10-09 | Salk Institute For Biological Studies | Ppar agonists |
| WO2016057658A1 (en) | 2014-10-08 | 2016-04-14 | Mitobridge, Inc. | Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof |
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| KR20060080214A (ko) | 2003-09-26 | 2006-07-07 | 니뽄 다바코 산교 가부시키가이샤 | 잔여 리포프로테인 생산 저해 방법 |
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| MX2007009343A (es) | 2005-02-15 | 2007-09-21 | Hoffmann La Roche | Derivados de amida como activadores de receptor activado por proliferador de peroxisomas. |
| JP2009507846A (ja) * | 2005-09-07 | 2009-02-26 | プレキシコン，インコーポレーテッド | Ｐｐａｒ活性化合物 |
| US7723369B2 (en) | 2006-01-30 | 2010-05-25 | Transtech Pharma, Inc. | Substituted imidazole derivatives, compositions, and methods of use as PTPase inhibitors |
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| DE102006023336A1 (de) | 2006-05-18 | 2007-11-22 | Merck Patent Gmbh | 1,5-Diphenyl-pyrazole II |
| CN101085772A (zh) * | 2006-06-07 | 2007-12-12 | 上海艾力斯医药科技有限公司 | 一类具有PPARγ激动剂活性的化合物及其应用 |
| EP2128138A1 (en) | 2007-01-29 | 2009-12-02 | Takeda Pharmaceutical Company Limited | Pyrazole compound |
| US20100063041A1 (en) | 2007-03-07 | 2010-03-11 | Ho-Sang Moon | Novel phenylpropionic acid derivatives as peroxisome proliferator-activated gamma receptor modulators, method of the same, and pharmaceutical composition comprising the same |
| JP2008285452A (ja) | 2007-05-21 | 2008-11-27 | Ono Pharmaceut Co Ltd | ＰＰＡＲα／γデュアルアゴニストおよび糖尿病治療薬を組み合わせてなる医薬 |
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| WO2014033088A1 (en) | 2012-08-28 | 2014-03-06 | Koc Universitesi | Bone plate |
| WO2015035171A1 (en) | 2013-09-09 | 2015-03-12 | High Point Pharmaceuticals, Llc | Use of a ppar-delta agonist for treating muscle atrophy |
| WO2016057322A1 (en) | 2014-10-08 | 2016-04-14 | Salk Institute For Biological Studies | Ppar agonists and methods of use thereof |
| EP3770146B1 (en) | 2015-10-07 | 2024-07-24 | Astellas Engineered Small Molecules US, Incorporated | Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof |
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| WO2014165827A1 (en) | 2013-04-05 | 2014-10-09 | Salk Institute For Biological Studies | Ppar agonists |
| WO2016057658A1 (en) | 2014-10-08 | 2016-04-14 | Mitobridge, Inc. | Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof |
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| Publication | Publication Date | Title |
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| KR102667385B1 (ko) | Ppar 효능제, 화합물, 제약 조성물, 및 그의 사용 방법 | |
| EA039833B1 (ru) | Агонисты ppar, соединения, фармацевтические композиции и способы их применения |
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