MX2020011100A - Compuestos, composiciones farmaceuticas y metodos de uso de agonistas de ppar. - Google Patents

Compuestos, composiciones farmaceuticas y metodos de uso de agonistas de ppar.

Info

Publication number
MX2020011100A
MX2020011100A MX2020011100A MX2020011100A MX2020011100A MX 2020011100 A MX2020011100 A MX 2020011100A MX 2020011100 A MX2020011100 A MX 2020011100A MX 2020011100 A MX2020011100 A MX 2020011100A MX 2020011100 A MX2020011100 A MX 2020011100A
Authority
MX
Mexico
Prior art keywords
compounds
methods
pharmaceutical compositions
ppar agonists
diseases
Prior art date
Application number
MX2020011100A
Other languages
English (en)
Inventor
Bharat Lagu
Masanori Miura
Arthur Kluge
Taisuke Takahashi
Sunil Kumar Panigrahi
Ronald M Evans
Susanta Samajdar
Michael Downes
Michael Patane
Ramesh Senaiar
Original Assignee
Mitobridge Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57200096&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2020011100(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mitobridge Inc filed Critical Mitobridge Inc
Publication of MX2020011100A publication Critical patent/MX2020011100A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings

Abstract

Compuestos y composiciones de utilidad para aumentar la actividad de PPARd. Los compuestos y las composiciones provistos en la presente son útiles para el tratamiento de enfermedades relacionadas con PPARd (por ejemplo, enfermedades musculares, enfermedades vasculares, enfermedades desmielinizantes y enfermedades metabólicas).
MX2020011100A 2015-10-07 2016-10-05 Compuestos, composiciones farmaceuticas y metodos de uso de agonistas de ppar. MX2020011100A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562238629P 2015-10-07 2015-10-07
US201562243263P 2015-10-19 2015-10-19
US201662352348P 2016-06-20 2016-06-20
PCT/US2016/055521 WO2017062468A1 (en) 2015-10-07 2016-10-05 Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof

Publications (1)

Publication Number Publication Date
MX2020011100A true MX2020011100A (es) 2022-05-23

Family

ID=57200096

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020011099A MX2020011099A (es) 2015-10-07 2016-10-05 Compuestos, composiciones farmaceuticas y metodos de uso de agonistas de ppar.
MX2020011100A MX2020011100A (es) 2015-10-07 2016-10-05 Compuestos, composiciones farmaceuticas y metodos de uso de agonistas de ppar.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2020011099A MX2020011099A (es) 2015-10-07 2016-10-05 Compuestos, composiciones farmaceuticas y metodos de uso de agonistas de ppar.

Country Status (26)

Country Link
US (5) US10399958B2 (es)
EP (3) EP3770146A1 (es)
JP (2) JP6657413B2 (es)
KR (2) KR20210126150A (es)
CN (3) CN113024467A (es)
AU (3) AU2016333963C1 (es)
BR (1) BR112018006866B1 (es)
CA (1) CA3000431A1 (es)
CO (1) CO2018004473A2 (es)
DK (1) DK3359528T3 (es)
EA (1) EA037371B1 (es)
ES (2) ES2906379T3 (es)
HK (1) HK1257907A1 (es)
HU (1) HUE058154T2 (es)
IL (3) IL258225B (es)
JO (3) JO3738B1 (es)
MA (2) MA52648A (es)
MX (2) MX2020011099A (es)
PH (1) PH12018500762A1 (es)
PL (1) PL3359528T3 (es)
PT (1) PT3359528T (es)
SG (1) SG10201906400SA (es)
TW (3) TWI730408B (es)
UA (1) UA122237C2 (es)
WO (1) WO2017062468A1 (es)
ZA (4) ZA201802029B (es)

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DK3359528T3 (en) 2015-10-07 2022-03-07 Mitobridge Inc Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof
KR102430906B1 (ko) 2016-04-13 2022-08-10 미토브리지, 인크. Ppar 효능제, 화합물, 제약 조성물, 및 그의 사용 방법
US20210283116A1 (en) * 2016-10-05 2021-09-16 Mitobridge, Inc. Methods of treating acute kidney injury
PL3523283T3 (pl) * 2016-10-05 2021-12-13 Mitobridge, Inc. Postacie krystaliczne i postacie soli związków stanowiących agonistów ppar
US20220331267A1 (en) * 2019-09-05 2022-10-20 Rush University Medical Center Methods and compositions for treatment of demyelinating disorders
US11634387B2 (en) 2019-09-26 2023-04-25 Abionyx Pharma Sa Compounds useful for treating liver diseases
WO2022189856A1 (en) 2021-03-08 2022-09-15 Abionyx Pharma Sa Compounds useful for treating liver diseases
CA3221429A1 (en) 2021-06-02 2022-12-08 Astellas Pharma Inc. Methods of use of ppar agonist compounds and pharmaceutical compositions thereof
WO2023147309A1 (en) 2022-01-25 2023-08-03 Reneo Pharmaceuticals, Inc. Use of ppar-delta agonists in the treatment of disease
EP4230196A1 (en) 2022-02-21 2023-08-23 Som Innovation Biotech, S.A. Compounds for use in the treatment of dystrophinopathies

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Also Published As

Publication number Publication date
IL258225A (en) 2018-05-31
EP3359528B1 (en) 2022-01-12
US10906885B2 (en) 2021-02-02
IL275392B (en) 2022-05-01
JOP20200231A1 (ar) 2022-10-30
US20230373948A1 (en) 2023-11-23
IL258225B (en) 2021-08-31
UA122237C2 (uk) 2020-10-12
DK3359528T3 (en) 2022-03-07
JP6657413B2 (ja) 2020-03-04
TW201943705A (zh) 2019-11-16
EP3359528A1 (en) 2018-08-15
TWI742479B (zh) 2021-10-11
TWI730006B (zh) 2021-06-11
ES2949852T3 (es) 2023-10-03
US10399958B2 (en) 2019-09-03
AU2019283837A1 (en) 2020-01-16
PL3359528T3 (pl) 2022-05-30
CN113024467A (zh) 2021-06-25
US20190337920A1 (en) 2019-11-07
MA52098A (fr) 2021-01-27
EA037371B1 (ru) 2021-03-19
JOP20200230A1 (ar) 2022-10-30
SG10201906400SA (en) 2019-08-27
TWI730408B (zh) 2021-06-11
EA201890776A1 (ru) 2018-09-28
US10479775B1 (en) 2019-11-19
JP6866514B2 (ja) 2021-04-28
AU2016333963A1 (en) 2018-04-12
AU2016333963C1 (en) 2021-05-27
CN113004205A (zh) 2021-06-22
CO2018004473A2 (es) 2018-09-20
MA52648A (fr) 2021-10-13
BR112018006866A2 (pt) 2018-10-16
WO2017062468A1 (en) 2017-04-13
KR20180095797A (ko) 2018-08-28
HK1257907A1 (zh) 2019-11-01
EP3795566B1 (en) 2023-04-19
ZA202003663B (en) 2022-08-31
PH12018500762A1 (en) 2018-10-29
TW202012375A (zh) 2020-04-01
TW201722919A (zh) 2017-07-01
US11578052B2 (en) 2023-02-14
US20200157074A1 (en) 2020-05-21
MX2020011099A (es) 2022-05-23
ZA201802029B (en) 2022-01-26
JP2018534355A (ja) 2018-11-22
US20190084958A1 (en) 2019-03-21
CA3000431A1 (en) 2017-04-13
IL275387B (en) 2021-08-31
JP2020075939A (ja) 2020-05-21
AU2020281069B2 (en) 2022-10-27
US20210253549A1 (en) 2021-08-19
IL275392A (en) 2020-07-30
CN108349904B (zh) 2021-08-31
ES2906379T3 (es) 2022-04-18
AU2016333963B2 (en) 2021-01-07
ZA202003662B (en) 2022-08-31
EP3795566A1 (en) 2021-03-24
AU2020281069A1 (en) 2021-01-07
BR112018006866B1 (pt) 2023-11-21
ZA202003664B (en) 2022-08-31
WO2017062468A8 (en) 2017-05-11
JO3738B1 (ar) 2021-01-31
EP3770146A1 (en) 2021-01-27
AU2019283837B2 (en) 2020-12-24
CN108349904A (zh) 2018-07-31
KR20210126150A (ko) 2021-10-19
PT3359528T (pt) 2022-04-07
IL275387A (en) 2020-07-30
HUE058154T2 (hu) 2022-07-28

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