MX2016012262A - Cenicriviroc para el tratamiento de fibrosis. - Google Patents
Cenicriviroc para el tratamiento de fibrosis.Info
- Publication number
- MX2016012262A MX2016012262A MX2016012262A MX2016012262A MX2016012262A MX 2016012262 A MX2016012262 A MX 2016012262A MX 2016012262 A MX2016012262 A MX 2016012262A MX 2016012262 A MX2016012262 A MX 2016012262A MX 2016012262 A MX2016012262 A MX 2016012262A
- Authority
- MX
- Mexico
- Prior art keywords
- cenicriviroc
- fibrosis
- treatment
- peritonitis
- solvate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7052—Fibrosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Nutrition Science (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Inorganic Chemistry (AREA)
- Physiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
Abstract
La presente descripción se relaciona con composiciones farmacéuticas que contienen cenicriviroc, métodos para la preparación de estas y su uso en el tratamiento de la inflamación y trastornos y enfermedades de tejido conjuntivo, especialmente la fibrosis.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461968829P | 2014-03-21 | 2014-03-21 | |
US201462024713P | 2014-07-15 | 2014-07-15 | |
US201562114304P | 2015-02-10 | 2015-02-10 | |
PCT/US2015/021828 WO2015143367A2 (en) | 2014-03-21 | 2015-03-20 | Cenicriviroc for the treatment of fibrosis |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016012262A true MX2016012262A (es) | 2017-01-06 |
Family
ID=54145485
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016012262A MX2016012262A (es) | 2014-03-21 | 2015-03-20 | Cenicriviroc para el tratamiento de fibrosis. |
Country Status (16)
Country | Link |
---|---|
US (3) | US20170239262A1 (es) |
EP (2) | EP3119401A4 (es) |
JP (1) | JP6556825B2 (es) |
KR (1) | KR20160132489A (es) |
CN (1) | CN106488769A (es) |
AU (2) | AU2015230986A1 (es) |
BR (1) | BR112016021682A2 (es) |
CA (1) | CA2941411A1 (es) |
CL (1) | CL2016002372A1 (es) |
HK (1) | HK1232147A1 (es) |
IL (1) | IL247515A0 (es) |
MA (1) | MA39748A (es) |
MX (1) | MX2016012262A (es) |
RU (2) | RU2724339C2 (es) |
SG (2) | SG10201808104RA (es) |
WO (1) | WO2015143367A2 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2459172C (en) | 2001-08-08 | 2011-07-05 | Takeda Chemical Industries, Ltd. | Bicyclic compound, production and use thereof |
US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
US10174289B2 (en) | 2014-05-28 | 2019-01-08 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
WO2016040860A1 (en) * | 2014-09-12 | 2016-03-17 | Tobira Therapeutics, Inc. | Cenicriviroc combination therapy for the treatment of fibrosis |
WO2016061464A1 (en) | 2014-10-17 | 2016-04-21 | Children's Hospital Center, D/B/A Cincinnati Children's Hospital Medical Center | In vivo model of human small intetine using pluripotent stem cells and methods of making and using same |
JP6716568B2 (ja) | 2014-12-23 | 2020-07-01 | トビラ セラピューティクス, インコーポレイテッド | セニクリビロックの製造方法及び関連類似体 |
WO2017048322A1 (en) * | 2015-09-16 | 2017-03-23 | Tobira Therapeutics, Inc. | Cenicriviroc combination therapy for the treatment of fibrosis |
EP3391057B1 (en) * | 2015-12-16 | 2020-04-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Diagnostic markers of immunosenescence and methods for determining the susceptibility to nosocomial infections |
FR3050112B1 (fr) | 2016-04-15 | 2020-09-04 | Soc Civ Immobiliere Gecinq | Utilisation de l'acide fenofibrique dans le traitement des maladies hepatiques |
US11066650B2 (en) | 2016-05-05 | 2021-07-20 | Children's Hospital Medical Center | Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same |
US10407411B2 (en) | 2016-06-21 | 2019-09-10 | Tobira Therapeutics, Inc. | Purified cenicriviroc and purified intermediates for making cenicriviroc |
CN106248947A (zh) * | 2016-07-21 | 2016-12-21 | 中国人民解放军军事医学科学院基础医学研究所 | 一种哺乳动物高原脑水肿生物标志物及其应用 |
RU2019109019A (ru) | 2016-08-31 | 2020-10-01 | Тобира Терапьютикс, Инк. | Твердые формы ценикривирок мезилата и способы изготовления твердых форм ценикривирок мезилата |
KR102546194B1 (ko) | 2016-11-04 | 2023-06-21 | 칠드런즈 호스피탈 메디칼 센터 | 간 유사 장기 조성물 및 이를 제조 및 사용하는 방법 |
AU2017373767B2 (en) | 2016-12-05 | 2021-09-16 | Children's Hospital Medical Center | Colonic organoids and methods of making and using same |
MX2019009909A (es) * | 2017-02-24 | 2019-10-14 | Genfit | Composiciones farmaceuticas para terapia de combinacion. |
KR20200116912A (ko) * | 2018-02-02 | 2020-10-13 | 쓰촨 케룬-바이오테크 바이오파마수티컬 컴퍼니 리미티드 | 카르복실산기를 포함하는 질소-함유 벤조헤테로시클 화합물, 이의 제조 방법 및 이의 용도 |
GB201804922D0 (en) * | 2018-03-27 | 2018-05-09 | Ucl Business Plc | Traatment |
WO2021133811A1 (en) * | 2019-12-26 | 2021-07-01 | Teva Pharmaceuticals International Gmbh | Solid state forms of cenicriviroc and process for preparation thereof |
EP4192495A1 (en) * | 2020-08-07 | 2023-06-14 | Bristol-Myers Squibb Company | Fgf21 combined with ccr2/5 antagonists for the treatment of fibrosis |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2276706T3 (es) * | 1999-12-08 | 2007-07-01 | Teijin Limited | Antagonistas del receptor ccr5 de aminas ciclicas. |
CA2459172C (en) | 2001-08-08 | 2011-07-05 | Takeda Chemical Industries, Ltd. | Bicyclic compound, production and use thereof |
CH696628A5 (de) * | 2002-02-26 | 2007-08-31 | Eprova Ag | Verwendung von Folaten zur Herstellung einer Zubereitung geeignet zur Vorbeugung und Behandlung von Entzündungen und entzündungsassoziierter Krankheiten, im Speziellen zur Beeinflussung der |
JPWO2006059716A1 (ja) | 2004-12-03 | 2008-06-05 | 武田薬品工業株式会社 | 固形製剤 |
CA2608709A1 (en) * | 2005-05-31 | 2006-12-07 | Novartis Ag | Treatment of liver diseases in which iron plays a role in pathogenesis |
US7683176B2 (en) * | 2006-07-14 | 2010-03-23 | Chemocentryx, Inc. | Triazolyl pyridyl benzenesulfonamides |
US20080194575A1 (en) * | 2006-10-04 | 2008-08-14 | Naiara Beraza | Treatment for non-alcoholic-steatohepatitis |
WO2008060783A2 (en) * | 2006-10-05 | 2008-05-22 | Centocor Ortho Biotech Inc. | Ccr2 antagonists for treatment of fibrosis |
RU2337365C1 (ru) * | 2006-12-12 | 2008-10-27 | Государственное образовательное учреждение высшего профессионального образования Новосибирский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию (ГОУ ВПО НГМУ Росздрава) | Способ дифференциальной диагностики алкогольного и неалкогольного стеатогепатита |
RU2435593C2 (ru) * | 2009-07-21 | 2011-12-10 | Лев Давидович Раснецов | Фармацевтическая композиция для лечения сахарного диабета 2 типа и лекарственное средство на его основе |
CA2911212A1 (en) * | 2013-05-15 | 2014-11-20 | Tobira Therapeutics, Inc. | Cenicriviroc compositions and methods of making and using the same |
-
2015
- 2015-03-20 CN CN201580021915.3A patent/CN106488769A/zh active Pending
- 2015-03-20 JP JP2017501137A patent/JP6556825B2/ja not_active Expired - Fee Related
- 2015-03-20 EP EP15765327.0A patent/EP3119401A4/en not_active Withdrawn
- 2015-03-20 KR KR1020167028892A patent/KR20160132489A/ko not_active Application Discontinuation
- 2015-03-20 EP EP21158407.3A patent/EP3922246A1/en not_active Withdrawn
- 2015-03-20 US US15/127,720 patent/US20170239262A1/en not_active Abandoned
- 2015-03-20 MA MA039748A patent/MA39748A/fr unknown
- 2015-03-20 SG SG10201808104RA patent/SG10201808104RA/en unknown
- 2015-03-20 SG SG11201607859SA patent/SG11201607859SA/en unknown
- 2015-03-20 BR BR112016021682-2A patent/BR112016021682A2/pt not_active Application Discontinuation
- 2015-03-20 CA CA2941411A patent/CA2941411A1/en not_active Abandoned
- 2015-03-20 RU RU2016141281A patent/RU2724339C2/ru active
- 2015-03-20 WO PCT/US2015/021828 patent/WO2015143367A2/en active Application Filing
- 2015-03-20 MX MX2016012262A patent/MX2016012262A/es unknown
- 2015-03-20 AU AU2015230986A patent/AU2015230986A1/en not_active Abandoned
- 2015-03-20 RU RU2020119611A patent/RU2020119611A/ru unknown
-
2016
- 2016-08-28 IL IL247515A patent/IL247515A0/en unknown
- 2016-09-21 CL CL2016002372A patent/CL2016002372A1/es unknown
-
2017
- 2017-06-14 HK HK17105882.1A patent/HK1232147A1/zh unknown
-
2018
- 2018-10-01 US US16/148,749 patent/US20190099429A1/en not_active Abandoned
-
2020
- 2020-04-30 US US16/863,711 patent/US20200368247A1/en not_active Abandoned
- 2020-06-11 AU AU2020203867A patent/AU2020203867A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
RU2016141281A3 (es) | 2018-10-26 |
JP2017509704A (ja) | 2017-04-06 |
RU2020119611A (ru) | 2020-06-29 |
AU2015230986A1 (en) | 2016-10-13 |
CA2941411A1 (en) | 2015-09-24 |
EP3119401A2 (en) | 2017-01-25 |
IL247515A0 (en) | 2016-11-30 |
CN106488769A (zh) | 2017-03-08 |
SG11201607859SA (en) | 2016-10-28 |
BR112016021682A2 (pt) | 2018-06-26 |
WO2015143367A2 (en) | 2015-09-24 |
AU2020203867A1 (en) | 2020-07-02 |
SG10201808104RA (en) | 2018-10-30 |
US20170239262A1 (en) | 2017-08-24 |
CL2016002372A1 (es) | 2017-02-10 |
EP3119401A4 (en) | 2017-12-13 |
KR20160132489A (ko) | 2016-11-18 |
US20190099429A1 (en) | 2019-04-04 |
HK1232147A1 (zh) | 2018-01-05 |
EP3922246A1 (en) | 2021-12-15 |
RU2724339C2 (ru) | 2020-06-23 |
US20200368247A1 (en) | 2020-11-26 |
RU2016141281A (ru) | 2018-04-23 |
JP6556825B2 (ja) | 2019-08-07 |
MA39748A (fr) | 2021-04-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2016012262A (es) | Cenicriviroc para el tratamiento de fibrosis. | |
MX2021009673A (es) | Moduladores de ror-gamma. | |
IL256085B (en) | A substituted derivative of cholanoic acid, a pharmaceutical composition comprising it and the substituted derivative for use in treatment | |
PH12017500583A1 (en) | Dihydropyrrolopyridine inhibitors of ror-gamma | |
PH12016501457B1 (en) | Dihydropyrrolopyridine inhibitors of ror-gamma | |
CA2956871C (en) | Compounds active towards bromodomains | |
IL255509B (en) | Compounds as modulators of ccr2, pharmaceutical preparations containing them and their use in the treatment of diseases | |
EP3515420C0 (en) | PHARMACEUTICAL COMPOSITIONS FOR USE IN BLEPHARITIS THERAPY | |
MX2016012574A (es) | Compuestos heteroarilo sustituidos y metodos de uso. | |
EP3153170A4 (en) | Methods and uses of quinoline derivatives in the treatment of soft tissue sarcomas and pharmaceutical compositions for treatment of same | |
WO2015171558A3 (en) | BENZENESULFONAMIDO AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORγ AND THE TREATEMENT OF DISEASE | |
EP3328864A4 (en) | COMPOUNDS AND THERAPEUTIC COMPOSITIONS FOR THE TREATMENT OF SOCIAL DISORDERS AND ADDICTION-RELATED DISORDERS | |
PH12016501371A1 (en) | Pharmaceutical compositions comprising 15-hepe and methods of treating asthma and lung disorders using same | |
PH12016502233A1 (en) | (s)-pirlindole or its pharmaceutically acceptable salts for use in medicine | |
MX2017010277A (es) | Cenicriviroc para el tratamiento de la fibrosis. | |
PH12016502236A1 (en) | (r)-pirlindole and its pharmaceutically acceptable salts for use in medicine | |
EP3291818A4 (en) | Compositions and methods for delivering therapeutic agents into the colon | |
IL280389A (en) | Bile acid receptor modulators conjugated to G.1 protein and methods of using them | |
EP3456711A4 (en) | CASPASE INHIBITOR AND PHARMACEUTICAL COMPOSITION, USE AND THERAPEUTIC METHOD THEREFOR | |
EP3119387A4 (en) | Compositions for the treatment of dermatological diseases and disorders | |
IL256919A (en) | Pharmaceutical compositions useful for the treatment of tissue damage | |
EP3475442A4 (en) | 12 (S) -HYDROXYEICOSATRIENOIC ACID COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | |
EP3340985A4 (en) | PHARMACEUTICAL COMPOSITIONS AND METHOD FOR THE TREATMENT OF HYPOXIC-INFLAMMATORY DISEASES | |
WO2016083315A8 (en) | Use of ox1r antagonists for the treatment of inflammatory bowel diseases | |
EP3434271A4 (en) | USE OF A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF A GAUZE SYTHEM IN POIKILODERMIA |