KR102622784B1 - 항-돌연변이 kras t 세포 수용체 - Google Patents

항-돌연변이 kras t 세포 수용체 Download PDF

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KR102622784B1
KR102622784B1 KR1020177017289A KR20177017289A KR102622784B1 KR 102622784 B1 KR102622784 B1 KR 102622784B1 KR 1020177017289 A KR1020177017289 A KR 1020177017289A KR 20177017289 A KR20177017289 A KR 20177017289A KR 102622784 B1 KR102622784 B1 KR 102622784B1
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KR20170099905A (ko
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키옹 제이 왕
지야 유
제임스 씨 양
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더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
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    • A61K40/00—Cellular immunotherapy
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32—T-cell receptors [TCR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
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    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4244—Enzymes
    • A61K40/4253—GTPases, e.g. Ras or Rho
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C12Y306/00—Hydrolases acting on acid anhydrides (3.6)
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/54—Pancreas
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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KR1020177017289A 2014-11-26 2015-11-24 항-돌연변이 kras t 세포 수용체 Active KR102622784B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462084654P 2014-11-26 2014-11-26
US62/084,654 2014-11-26
US201562171321P 2015-06-05 2015-06-05
US62/171,321 2015-06-05
PCT/US2015/062269 WO2016085904A1 (en) 2014-11-26 2015-11-24 Anti-mutated kras t cell receptors

Publications (2)

Publication Number Publication Date
KR20170099905A KR20170099905A (ko) 2017-09-01
KR102622784B1 true KR102622784B1 (ko) 2024-01-09

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US (3) US11207394B2 (https=)
EP (3) EP3223850B1 (https=)
JP (2) JP6863893B2 (https=)
KR (1) KR102622784B1 (https=)
CN (3) CN118994363A (https=)
AU (3) AU2015353720B2 (https=)
ES (2) ES2965689T3 (https=)
HU (1) HUE065689T2 (https=)
IL (1) IL252258B (https=)
MX (1) MX384919B (https=)
PL (1) PL3223850T3 (https=)
PT (1) PT3223850T (https=)
SA (1) SA517381608B1 (https=)
SG (2) SG11201704155UA (https=)
SI (1) SI3223850T1 (https=)
WO (1) WO2016085904A1 (https=)

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