KR102200892B1 - 펠루비프로펜의 신규 염, 이의 제조방법 및 이를 포함하는 약학적 조성물 - Google Patents
펠루비프로펜의 신규 염, 이의 제조방법 및 이를 포함하는 약학적 조성물 Download PDFInfo
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- KR102200892B1 KR102200892B1 KR1020190055671A KR20190055671A KR102200892B1 KR 102200892 B1 KR102200892 B1 KR 102200892B1 KR 1020190055671 A KR1020190055671 A KR 1020190055671A KR 20190055671 A KR20190055671 A KR 20190055671A KR 102200892 B1 KR102200892 B1 KR 102200892B1
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- Prior art keywords
- felubiprofen
- tromethamine
- present
- tromethamine salt
- pelubiprofen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/86—Unsaturated compounds containing keto groups containing six-membered aromatic rings and other rings
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/80—Unsaturated compounds containing keto groups containing rings other than six-membered aromatic rings
- C07C59/82—Unsaturated compounds containing keto groups containing rings other than six-membered aromatic rings the keto group being part of a ring
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
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- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020190055671A KR102200892B1 (ko) | 2019-05-13 | 2019-05-13 | 펠루비프로펜의 신규 염, 이의 제조방법 및 이를 포함하는 약학적 조성물 |
CN202080030464.0A CN113891873B (zh) | 2019-05-13 | 2020-05-12 | 新型培比洛芬盐、其制备方法及包含其的药物组合物 |
PCT/KR2020/006219 WO2020231146A1 (fr) | 2019-05-13 | 2020-05-12 | Nouveau sel de pélubiprofène, son procédé de préparation et composition pharmaceutique le comprenant |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020190055671A KR102200892B1 (ko) | 2019-05-13 | 2019-05-13 | 펠루비프로펜의 신규 염, 이의 제조방법 및 이를 포함하는 약학적 조성물 |
Publications (2)
Publication Number | Publication Date |
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KR20200131382A KR20200131382A (ko) | 2020-11-24 |
KR102200892B1 true KR102200892B1 (ko) | 2021-01-12 |
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KR1020190055671A KR102200892B1 (ko) | 2019-05-13 | 2019-05-13 | 펠루비프로펜의 신규 염, 이의 제조방법 및 이를 포함하는 약학적 조성물 |
Country Status (3)
Country | Link |
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KR (1) | KR102200892B1 (fr) |
CN (1) | CN113891873B (fr) |
WO (1) | WO2020231146A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102372908B1 (ko) | 2021-09-27 | 2022-03-10 | 유니셀랩 주식회사 | 새로운 펠루비프로펜/만델산 공결정 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023080299A1 (fr) * | 2021-11-08 | 2023-05-11 | 일동제약(주) | Nouveau sel d'un dérivé de l'acide phénylpropionique, son procédé de production et composition pharmaceutique le contenant |
WO2023182869A1 (fr) * | 2022-03-25 | 2023-09-28 | Ildong Pharmaceutical Co., Ltd. | Nouveau sel de composé agoniste du récepteur glp-1, son procédé de préparation et composition pharmaceutique le comprenant |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS6038323A (ja) * | 1983-08-10 | 1985-02-27 | Sankyo Co Ltd | 眼科用消炎剤 |
WO2001037838A1 (fr) * | 1999-11-24 | 2001-05-31 | Wakamoto Pharmaceutical Co., Ltd. | Preparation aqueuse ophtalmique |
ES2343168T3 (es) * | 2001-05-31 | 2010-07-26 | Hisamitsu Pharmaceutical Co., Inc. | Parches de absorcion por via percutanea. |
EP2098500A1 (fr) * | 2008-03-07 | 2009-09-09 | Laboratorios Del. Dr. Esteve, S.A. | Sels de Ménantine et co-inhibiteur et leur forme cristalline pour le traitement de la douleur |
KR100922519B1 (ko) | 2008-11-12 | 2009-10-20 | 대원제약주식회사 | 펠루비프로펜을 함유하는 용출률 및 안정성이 개선된 경구투여용 약제학적 제제 |
CN102093234B (zh) * | 2009-11-26 | 2014-06-18 | 福州乾正药业有限公司 | 一种二元酯酸的氨丁三醇盐化合物及其制备方法和药物应用 |
CN102743341B (zh) * | 2012-07-28 | 2014-02-26 | 西安德天药业股份有限公司 | 右旋酮洛芬氨丁三醇缓释微粒及其制备方法和缓释制剂 |
HU231045B1 (en) * | 2015-12-01 | 2020-01-28 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Zrt | Novel process for the preparation of carboprost tromethamine |
JP1637767S (fr) | 2018-12-03 | 2019-07-29 |
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2019
- 2019-05-13 KR KR1020190055671A patent/KR102200892B1/ko active IP Right Grant
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2020
- 2020-05-12 CN CN202080030464.0A patent/CN113891873B/zh active Active
- 2020-05-12 WO PCT/KR2020/006219 patent/WO2020231146A1/fr active Application Filing
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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KR102372908B1 (ko) | 2021-09-27 | 2022-03-10 | 유니셀랩 주식회사 | 새로운 펠루비프로펜/만델산 공결정 |
Also Published As
Publication number | Publication date |
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KR20200131382A (ko) | 2020-11-24 |
CN113891873A (zh) | 2022-01-04 |
WO2020231146A1 (fr) | 2020-11-19 |
CN113891873B (zh) | 2024-03-15 |
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