KR102140958B1 - Method for manufacturing functional shampoo having antimicrobial effect containing peppermint, cinnamon, oregano, ginger Extract - Google Patents

Abstract

The present invention relates to a method for preparing a functional shampoo having an antibacterial effect by containing peppermint, cinnamon, oregano, and ginger extracts, and more specifically, by extracting and using natural ingredients, antibacterial activity without causing inflammation to the scalp even after prolonged use. Not only has excellent effect, but also has anti-oxidant effect by polyphenol, promotes scalp health, prevents aging of scalp, and contains improved mint, cinnamon, oregano, and ginger extracts to maintain stable foaming and emulsifying properties without discoloration. It relates to a method for manufacturing a functional shampoo having an effect.

Description

Method for manufacturing functional shampoo having antimicrobial effect containing peppermint, cinnamon, oregano, ginger extract}

The present invention relates to a method for preparing a functional shampoo having an antibacterial effect by containing peppermint, cinnamon, oregano, and ginger extracts, and more specifically, by extracting and using natural ingredients, antibacterial activity without causing inflammation to the scalp even after prolonged use. Not only has excellent effect, but also has anti-oxidant effect by polyphenol, promotes scalp health, prevents aging of scalp, and contains improved mint, cinnamon, oregano, and ginger extracts to maintain stable foaming and emulsifying properties without discoloration. It relates to a method for manufacturing a functional shampoo having an effect.

Hair protects the head from external stimuli such as direct sunlight and physical friction, and is involved in maintaining the temperature of the body, and plays a role in showing individual characteristics in the modern age when personality is important.

In modern people, the important clue that determines the overall impression of a person in interpersonal relationships is the face, and the role of hair is a very important aesthetic factor.

Normally, the main component of hair is made of protein, and wastes, sweat, and dust floating in the air adhere to the hair.

As these waste products are entangled and oxidized with sebum from the scalp, they smell and generate bacteria, so the hair is cleaned to remove these waste products, and various functional shampoos are currently released in this regard.

Shampoos vary depending on the type, but mainly anionic, amphoteric and nonionic surfactants usually account for 40 to 50% of the total ingredients.

Surfactants often cause skin irritation by removing excess lipids on the skin when used heavily. They melt the cuticle, a protein that wraps the hair, to remove hair gloss, and possibly destroy the stratum corneum, causing inflammation to the scalp.

Therefore, due to frequent use of chemicals and incorrect lifestyle, physiological functions of the scalp are damaged and may cause scalp seborrheic dermatitis and seborrheic alopecia.

On the other hand, dandruff is a phenomenon in which keratinocytes in the scalp are severely formed in the shape of a rice bran without inflammation such as redness or swelling.

It is commonly referred to as dandruff, which falls into a large lump with abnormally increased exfoliation of the stratum corneum, which is controversial in disease classification, but is known as the most common and mild form of seborrheic dermatitis. There are also severe cases.

Republic of Korea Patent Registration No. 10-1216538 (2012.12.21.)'Shampoo composition containing a nano-aqueous solution of polyurushiol, its manufacturing method and use for preventing anti-dandruff bacteria and hair loss', Applicant: Korea National Co., Ltd. Republic of Korea Patent Registration No. 10-1342556 (Dec. 11, 2013)'Conditioning shampoo composition with enhanced antibacterial properties containing mud extract', Applicant: Chungwoon University Industry-Academic Cooperation Foundation Republic of Korea Patent Registration No. 10-1514524 (2015.04.16.)'Cleaning agent using an antimicrobial composition having an inhibitory function against the growth of antibiotic-resistant strains using cypress extract', Applicant: (Re) Jeonnam Biological Industry Promotion Agency Republic of Korea Patent Publication No. 10-2018-0054240 (2018.05.24.)'Method of manufacturing a hypoallergenic shampoo having a function of preventing hair loss and softening the scalp using a scrubber and natural antibacterial agent', Applicant: Madongi Corporation

The present invention was created to solve the above-mentioned problems in the prior art as described above, and extracts and uses natural ingredients, so that it does not cause inflammation on the scalp even after long-term use, but also has excellent antibacterial activity and polyphenols. It has an antioxidant effect by promoting scalp health, preventing aging of the scalp, and improving the ability to maintain stable foaming and emulsifying properties without discoloration. It contains improved peppermint, cinnamon, oregano, and ginger extracts to produce a functional shampoo with an antibacterial effect. Its main purpose is to provide.

The present invention is a means for achieving the above object, 10% by weight of purified water, 20% by weight of ammonium lauryl sulfate, 20% by weight of sodium lauroyl sacosinate, and 5% by weight of disodium laureth sulfosuccinate Wow, 10% by weight of cocamidopropyl betaine, 2% by weight of glycol distearate, 4% by weight of stearimonium chloride, 0.05% by weight of quaternium-60, and 0.05% by weight of ethylenediamineteraacetic acid Wow, in the method of producing a functional shampoo having an antibacterial effect using a composition consisting of 5% by weight of propylene glycol, 5% by weight of glycerin and the remaining composite solution;
A complex solution preparation step of mixing each extract extracted from peppermint, oregano, ginger, and cinnamon in a weight ratio of 1:1:1:1 to make a complex solution;
Ammonium lauryl sulfate, sodium lauroyl sacosinate, disodium laureth sulfosuccinate, cocamidopropyl betaine, glycol distearate, steartrimonium chloride, and quaternium-60 in purified water And, ethylene diamine teraacetic acid, propylene glycol and glycerin are first blended, and then heated to 70° C. to uniformly dissolve the shampoo basic component composition step;
It includes; adding the composite solution while stopping heating of the basic component solution of the shampoo and then cooling to room temperature while stirring at a low speed of 10-20 rpm to make a shampoo;
In the step of preparing the composite solution, 5.5 parts by weight of hydroxytyrosol, 8.0 parts by weight of isoquinoline alkaloid, and 12 parts by weight of emulsified Kenaf fermented water are added, based on 100 parts by weight of the composite solution,
The Kenaf fermented emulsified water contains an aqueous solution consisting of 3% by weight of clay, 2% by weight of Kenaf leaves, 2% by weight of Kenaf charcoal, and the rest of the water in a jar. Course 1; 2% by weight of Kenaf fermented leaf stems fermented to Natillus (Bacillus Subtilis natto), 6% by weight of Kenaf marinated sugar, 5% by weight of yogurt, 2.5% by weight of dry yeast, and the rest of the aqueous solution of the above ground water 25- A second process of fermenting for 6 days in the dark condition of 30°C; It is characterized by being prepared through a third process of mixing Kenaf fermentation broth and caustic soda made through the second process in a weight ratio of 2.5:1 and aging in dark conditions at room temperature for 30 days to make natural Kenaf fermented emulsified water; It provides a method of manufacturing a shampoo using a functional shampoo composition having an antimicrobial effect containing peppermint, cinnamon, oregano, and ginger extract.

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According to the present invention, by using natural ingredients extracted and used for a long time, not only does not cause inflammation on the scalp, it has excellent antibacterial activity, and also has an antioxidant effect by polyphenols to promote scalp health and prevent scalp aging, It is possible to obtain an effect of improving so as to maintain stable foamability and emulsification property without discoloration.

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Hereinafter, a preferred embodiment according to the present invention will be described in more detail.

The composition for preparing a functional shampoo having an antibacterial effect by containing mint, cinnamon, oregano and ginger extract according to the present invention is 10% by weight of purified water, 20% by weight of ammonium lauryl sulfate, and 20% by weight of sodium lauroyl sacosinate. %, 5% by weight of disodium laureth sulfosuccinate, 10% by weight of cocamidopropyl betaine, 2% by weight of glycol distearate, 4% by weight of stearimonium chloride, and quaternium- 60 0.05% by weight, ethylenediamine teraacetic acid 0.05% by weight, propylene glycol 5% by weight, glycerin 5% by weight and the remaining composite solution.

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At this time, the ammonium lauryl sulfate (Ammonium lauryl sulfate) is added to enhance the surface active function to enhance the cleaning power.

And, the sodium lauroyl sarcosinate is added to enhance the conditioning of the hair.

In addition, the disodium laureth sulfosuccinate (Disodium Laureth Sulfosuccinate) is added to enhance the hydrophilicity to promote foaming, thereby increasing the cleaning power.

In addition, the cocamidopropyl betain is added to prevent the generation of static electricity and to enhance the water-soluble thickening function.

In addition, the glycol distearate (Giycol Distearate) is added to maintain the softening of the composition.

Furthermore, the steartrimonium chloride is added to maintain the condition of the hair and enhance the moisturizing property while preventing charging.

And, the quaternium-60 (Quarternium-60) is added to help prevent hair damage and keep it shiny.

In addition, the ethylene diamine terachoacetic acid (Disodium Ethylenediamine-tetraacetate) is added to prevent discoloration and to suppress rancidity.

In addition, since the propylene glycol (Propylene Glycol) has a small molecular weight and excellent skin penetration of the scalp, it is added to function as a carrier during cell penetration of the moisturizing component.

In addition, the glycerin is added to enhance the moisturizing power by hydrophilicity.

Furthermore, the complex solution is freeze-dried with a mixture of peppermint extract, oregano extract, ginger extract and cinnamon extract in a weight ratio of 1:1:1:1, and then the mixture and butylene glycol are mixed in a weight ratio of 3:7. It is made by mixing.

At this time, peppermint is a perennial plant belonging to the family Lamiaceae, which has the effect of blasting, antipyretic, detoxifying, and has a therapeutic effect on fever, headache, sore throat, abdominal swelling, toothache, and skin ulcer. (Lee Seung-eun et al., 2005, Lee et al., 2005).

In addition, oregano is a herb plant belonging to the genus Lamiaceae, which has a unique scented herb, the stem is square, and the leaves are mostly whole leaves, with beautiful flowers and scents as shrubs or herbs, which are cultivated for ornamental purposes, and are widely used as a raw material for spices. It contains a lot of phenolic compounds, especially rosmarinic acid, and has been reported to have anti-inflammatory, antioxidant, antibacterial, antifungal and antiviral properties (Choi Moo-young, Lim Tae-jin. 2008. Oregano extract has antibacterial effects on food poisoning bacteria. Society, 21: 352-356).

And, ginger refers to the non-dried rhizome of the ginger family (Zingiberaceae), and has been used for a long time all over the world due to its unique aroma and spiciness, and is a spice that is used in food and beverage in Korea. In oriental medicine, it is effective for indigestion, vomiting, diarrhea, and its pharmacological effects are known to be effective in antioxidant, anti-tumor, anti-inflammatory, hypoglycemic, insulin secretion, hyperlipidemia prevention and arthritis, and ginger is a phenolic compound such as gingerol. And flavonoids, terpenoids, and other compounds have been reported to exhibit various physiological activities (Bae Jong-seop, Taehoon Kim, 2011. Pancreatic lipase inhibition and antioxidant activity of ginger extract. Korean Society of Food Preservation and Distribution. 18: 390- 396).

In addition, the cinnamon tree (Cinnamoum cassia) is an evergreen tree that is about 7 to 8 m long and is cultivated in the mountains. The shape is a semi-tubular, semi-normal or tubular bark that is rolled into the Han Chinese. Is diverse. The outer surface of these cinnamon trees is dark reddish brown and the inner surface is flat, but it is also reddish brown and easy to break. And, the cinnamon tree has a peculiar scent, the taste is slightly sweet at first, it is very sweet, and later it becomes mucous and salty, and its medicinal properties are dry stomach, headache, cold, warm stomach, whole blood veins, main heart pain, and used for fragrances and spices. Is known.

And, the reason for dissolving the mixture in butylene glycol to make it a solution is usually used as a solvent in the manufacture of cosmetics in the case of butylene glycol, but in the present invention, it is not a solvent but has a moisturizing power due to its own wettability, so that penetration of the extract during skin deposition is prevented. It is utilized as an easy carrier, and above all, it is intended to reduce the antibacterial activity and sticky properties of the composition, thereby enhancing the characteristics of the extract and reducing irritation to the skin.

Therefore, it is not used as a solvent as in the manufacturing method described later, and thus is added last.

Thus, in the present invention, the extract extracted from natural plants or trees is used to increase the antibacterial activity while promoting the scalp health by preventing the aging of the scalp by preventing the aging of the scalp, and stable foamability and emulsification without discoloration. Provided is an improved shampoo composition for maintenance, a method for manufacturing the same, and a shampoo prepared by the method.

In addition, in the present invention, the composite solution is further added by adding 5.5 parts by weight of hydroxytyrosol, 8.0 parts by weight of isoquinoline alkaloid, and 12 parts by weight of emulsified Kenaf fermented water based on 100 parts by weight of the complex solution. can do.

At this time, the hydroxytyrosol will contribute to soothe the inflammation of the scalp, and the isoquinoline alkaloid is an extract extracted from Bitter Melon, Cinnamon Root, Barberry Root, and fungi as well as Salmonella. It is a natural antibacterial agent for a widely known fungus.

In addition, the Kenaf fermented emulsified water is added to further enhance antiviral, anti-inflammatory and antioxidant functions, and is prepared through the following process.

That is, the Kenaf fermented emulsified water contained an aqueous solution consisting of 3% by weight of clay, 2% by weight of Kenaf leaves, 2% by weight of Kenaf charcoal, and the rest of the water in a jar, and allowed to stand for 30 days. A first process of obtaining; 25% by weight of 2% by weight of Kenaf fermented leaf stems fermented in Natillus (Bacillus Subtilis natto), 6% by weight of Kenaf marinated sugar, 5% by weight of yogurt, 2.5% by weight of dry yeast, and the rest of the Jijangsu A second process of fermenting for 6 days in the dark condition of 30°C; It is prepared through the third process of mixing the Kenaf fermentation broth and caustic soda made through the second process in a weight ratio of 2.5:1 to make natural Kenaf fermented emulsified water by aging in dark conditions at room temperature for 30 days.

Here, Kenaf (Hibiscus cannabinus L.) is a hemp (洋麻) cultivated in India, Bangladesh, Thailand, etc. for the purpose of obtaining ordinary fibers. In the present invention, nitrogen and phosphorus are absorbed to improve or purify water quality. , It is used to strengthen the anti-inflammatory and UV protection of caustic soda by toxic absorption and removal.

In other words, the leaves of Kenaf contain four times the amount of calcium in milk, a large amount of protein, vitamins and iron, and a large amount of antioxidants that inhibit the action of free radicals, which has anti-inflammatory and antiviral functions. It is reported.

However, in the present invention, rather than simply adding it, it has a distinctive feature in that it is used by fermentation or charcoal treatment to enhance the characteristic expression. In particular, when carbonized, bulking occurs, and the refining capacity is significantly increased.

In addition, the clay is a kind of kaolinite having a honeycomb structured surface containing silica, alumina, iron, calcium, magnesium, potassium, sodium, titanium, etc., and has high decontamination and detoxification functions due to its high purifying and decomposing power due to the photoelectric effect. , It is added to take advantage of the anti-aging properties due to the cell activation, anti-inflammatory properties by actively physiological action of the cells.

In addition, natto bacteria for fermenting the Kenaf leaf stem is used to enhance the production of Kenaf glycase. This is to promote fermentation, and in the process, the above-mentioned ingredients contained in the leaves and stems of canaps are naturally extracted.

In addition, the Kenaf pickles and yogurt are added to promote fermentation, so that Hyogo bacteria or lactic acid bacteria are rapidly activated, and the dry yeast is an yeast for fermentation as dried yeast, and the reason for dark fermentation is ultraviolet light. This is to increase fermentation efficiency while suppressing harmful factors by blocking low temperature fermentation while suppressing photofermentation by blocking.

In this way, when the Kenaf fermentation broth and caustic soda are mixed in an appropriate ratio and aged in a dark condition at room temperature for a titration period, such as 30 days, natural Kenaf fermented emulsified water from which the toxicity of caustic soda is removed can be obtained. . At this time, at least the Kenaf fermentation broth should be added at least twice as much as caustic soda to detoxify and remove the toxicity of caustic soda.

On the other hand, the method of manufacturing a shampoo using a functional shampoo composition having an antibacterial effect by containing mint, cinnamon, oregano, and ginger extract according to the present invention is as follows.

First, a composite solution manufacturing step is performed.

In the complex solution preparation step, each extract extracted from peppermint, oregano, ginger, and cinnamon is mixed in a weight ratio of 1:1:1:1, and then an additive mixture and butylene glycol are added and mixed in a volume ratio of 3:7. Course 1; A second process in which the mixture mixed in the first process is left at room temperature for 3 days, filtered, concentrated under reduced pressure and freeze-dried; It consists of a third process of mixing and dissolving the lyophilized mixed powder with butylene glycol in a 3:7 weight ratio to make a solution.

At this time, the reason for making the extract mixture in powder form is to enable quantitative mixing to maximize efficacy, and to exclude the risk of deterioration and change due to chemical reaction when formulated in solution, using butylene glycol The reason is as described above.

Subsequently, a basic component composition step of shampoo is performed.

The basic component composition steps of the shampoo include ammonium lauryl sulfate, sodium lauroyl sacosinate, disodium laureth sulfosuccinate, cocamidopropyl betaine, glycol distearate, and stearate in the purified water described above. It is a step of uniformly dissolving atrimonium chloride, quaternium-60, ethylenediamine teraacetic acid, propylene glycol and glycerin first, followed by heating to 70°C.

As described above, before adding the composite solution, the basic components of the shampoo should be heated and dissolved so that the composite solution is added without further heating in the state of maintaining the solution.

This is to prevent this because the butylene glycol must be heated to a temperature higher than 80°C because it boils when it exceeds 80℃, and the reason for not adding it from the beginning may also change during the heating process. .

Subsequently, a step of adding a complex solution is performed, and after stopping the heating of the basic component solution of the shampoo, after adding the complex solution, the mixture is cooled to room temperature with slow stirring at a rate of 10-20 rpm to make the shampoo according to the present invention. .

Hereinafter, the antibacterial, stability, and allergic activities of the shampoo according to the present invention were tested.

First, in order to confirm the antimicrobial effect, three strains that cause inflammation among skin fungi ( Staphylococcus epidermidis, Staphylococcus aureus, Propionibacterium acnes ), and two types of bacteria causing folliculitis and dandruff ( Pityrosporum ovale, Malassezia furfur ), Candida albiacans , Trichophyton mentagrophytes) were cultured for antibacterial experiments.

The antibacterial activity was conducted by analyzing the antibacterial activity of the shampoo by paper disc.

To this end, the concentration of each test bacteria was adjusted to an optical density (OD) value of 0.4 (10 ⁶ CFU/ml) at 650 nm, and then used to make a culture plate for inoculation of bacteria. After placing the sterilized 8 mm paper disc, 40 μL of the shampoo solution containing the extract was absorbed, followed by incubation at an appropriate temperature for 12 to 24 hours, and then the diameter of the clear zone around the disc was measured. The degree of clear zone (mm) was calculated according to the following equation.

clear zone(mm)= diameter of clear zone-diameter of paper disc

Bacteria Inhibition zone diameter(mm) S. epidermidis 8 S. aureus 10 P. acnes 11 P. ovale 10 M. furfur 10 C. albiacans 8 T.mentagrophytes 12

As shown in Table 1, it was confirmed that there is an antibacterial effect on all bacteria.

In addition, in order to confirm the stability of the shampoo, stability according to temperature, pH change, discoloration, and odor were confirmed.

First, other stability checks were performed as follows.

The shampoo according to the present invention at different temperatures (25° C., 40° C. and 60° C.) for 12 weeks was compared and checked for segregation and precipitation change in the normal shampoo.

As a result of comparison, it showed high stability without any change for 12 weeks.

In addition, the pH change was observed for 1 week, 2 weeks, 4 weeks, 8 weeks, and 12 weeks while the shampoo was stored at 25°C and compared with the existing shampoo.

As a result of the observation, the pH of the shampoo according to the present invention was 5.5 to 5.77, and there was almost no change in pH, and the conventional shampoo as a control was found to be pH 5.7 to 6.0.

In addition, as a result of observing the color and odor of the shampoo while processing under harsh experimental conditions (25℃, 40℃ and 60℃) to confirm discoloration and odor, there was no change in color and no specific odor in all shampoos. No phenomena such as segregation or aggregation were observed.

Therefore, it was confirmed that the shampoo according to the present invention has stability.

In addition, to confirm the antioxidant activity of the shampoo according to the present invention, ABTS (2,2'-azinobis-(3-ethyl-benzothiazoline-6-sulphonic acid) radical scavenging activity measurement, polyphenol content measurement, total flavonoid content measurement Did.

As a result of the measurement, the scavenging activity of 96.21% of ABTS radical scavenging activity was confirmed, and the polyphenol content was 180.56±1.13 μg/mL and the total flavonoid content was 75.21±0.87 μg/mL, which was confirmed to have an antioxidant effect.

In addition, the effect of β-Hexosaminidase secretion on the shampoo sample was confirmed to confirm allergic activity.

This is a method suitable for confirming the anti-allergic effect of measuring the amount of granules such as histamine and prostaglandin, which are secreted from the cell to the outside in response to mast cells by antigen and antibody (Hong et al. , 2014).

In the present invention, the anti-allergic efficacy of the sample shampoo was confirmed by measuring the amount of β-hexosaminidase secreted to the outside of the cell.

At this time, the concentration was treated with 5, 10, 20, 50, 100 μg/mL, which is a concentration that does not affect the cells according to the cell viability measurement results, and for each concentration as a result of verification based on cells activated by antigens and antibodies The inhibition rates were 151.18%, 135.25%, 129.21%, 119.14%, and 110.27%.

Thereby, it was confirmed that there is also anti-allergic property.

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Claims (4)

delete 10% by weight of purified water, 20% by weight of ammonium lauryl sulfate, 20% by weight of sodium lauroyl sacosinate, 5% by weight of disodium laureth sulfosuccinate, 10% by weight of cocamidopropyl betaine, and writing 2% by weight of Lycoly distearate, 4% by weight of stearimonium chloride, 0.05% by weight of quaternium-60, 0.05% by weight of ethylenediamine teraacetic acid, 5% by weight of propylene glycol, and 5% by weight of glycerin And in the method for producing a functional shampoo having an antibacterial effect using the composition consisting of the remaining composite solution;
A complex solution preparation step of mixing each extract extracted from peppermint, oregano, ginger, and cinnamon in a weight ratio of 1:1:1:1 to make a complex solution;
Ammonium lauryl sulfate, sodium lauroyl sacosinate, disodium laureth sulfosuccinate, cocamidopropyl betaine, glycol distearate, steartrimonium chloride, and quaternium-60 in purified water And, ethylene diamine teraacetic acid, propylene glycol and glycerin are first blended, and then heated to 70° C. to uniformly dissolve the shampoo basic component composition step;
It includes; adding the composite solution while stopping heating of the basic component solution of the shampoo and then cooling to room temperature while stirring at a low speed of 10-20 rpm to make a shampoo;
In the step of preparing the composite solution, 5.5 parts by weight of hydroxytyrosol, 8.0 parts by weight of isoquinoline alkaloid, and 12 parts by weight of emulsified Kenaf fermented water are added, based on 100 parts by weight of the composite solution,
The Kenaf fermented emulsified water contains an aqueous solution consisting of 3% by weight of clay, 2% by weight of Kenaf leaves, 2% by weight of Kenaf charcoal, and the rest of the water in a jar, and left for 30 days. Course 1; 2% by weight of Kenaf fermented leaf stems fermented to Natillus (Bacillus Subtilis natto), 6% by weight of Kenaf marinated sugar, 5% by weight of yogurt, 2.5% by weight of dry yeast, and the rest of the aqueous solution of the above ground water 25- A second process of fermenting for 6 days in the dark condition of 30°C; It is characterized by being manufactured through a third process of mixing Kenaf fermentation broth and caustic soda made through the second process in a weight ratio of 2.5:1 and aging in dark conditions at room temperature for 30 days to make natural Kenaf fermented emulsified water; A method of manufacturing shampoo using a functional shampoo composition having antibacterial effect by containing peppermint, cinnamon, oregano, and ginger extract.
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