KR100534483B1 - Composition for improving state of scalp and hair comprising Panax ginseng C.A Meyer, Swertia japonica Makino, Cnidium Officinale Makino, Paeonia suffruticosa Andrews and Belamcanda chinensis De Candolle - Google Patents

Abstract

The present invention relates to a composition for improving the scalp and hair.

The composition of the present invention contains red ginseng, medicinal herbs, celestial organs, bark skin and panchae.

The composition of the present invention, hair loss prevention effect, hair growth effect, hair growth effect, wool effect, sebum overproduction effect, antibacterial effect against dandruff, anti-itch effect, moisturizing effect of scalp and hair, improving the flexibility of hair or preventing cracking It is excellent in effect and does not cause side effects even after long-term use.

Therefore, the composition of the present invention can be usefully used in various fields such as pharmaceuticals, quasi-drugs or cosmetics for improving the scalp and hair.

Description

Composition for improving state of scalp and hair comprising Panax ginseng C.A Meyer, Swertia japonica Makino, Cnidium Officinale Makino, Paeonia suffruticosa Andrews and Belamcanda chinensis De Candolle}

The present invention relates to a composition for improving the scalp and hair.

The human hair is about 100,000 to 150,000 pieces, each hair has a different cycle and grow and drop out through the growth phase, the degenerative phase, the resting phase. In normal people, this cycle is usually repeated over three to six years, resulting in an average of 60 to 100 hairs per day. On the other hand, in alopecia patients, hair loss in the growth phase during hair growth and dropping cycles decreases, and hair loss in the degenerative and resting phases increases, causing abnormal hair loss.

The causes of hair loss include poor blood circulation, excessive male hormone action, excessive sebum secretion, scalp hypofunction caused by dandruff and other bacteria, genetic factors, aging, and stress.

These factors work in combination to reduce hair loss, hair growth to make young hair grow better, hair loss to thicken and thicken hair without strength, sebum overproduction, dandruff growth, itching, scalp and It causes various symptoms of scalp and hair, such as drying hair, hair softness and cracking.

Recently, due to the increase in stress caused by changes in diet, social environment, etc., the number of people suffering from the above symptoms of scalp and hair is increasing, and the age is also decreasing, and the hair loss population of women is also increasing.

Accordingly, research has been conducted on compositions capable of preventing abnormal symptoms of various scalp and hair, including hair loss, and improving the condition of the scalp and hair.

Compositions that can improve the condition of the scalp and hair include hair loss prevention effect, hair growth effect, hair growth effect, wool effect, sebum overproduction effect, antibacterial effect against dandruff, anti itch, moisturizing effect of scalp and hair, hair It should be able to show good flexibility and preventing cracking effect.

In addition, the composition for the scalp and hair is often used over a long period of time due to the nature of use, and should not exhibit side effects such as irritating the scalp.

However, the scalp and hair related products that have been developed in the past are mostly effective only on one of the above symptoms, and thus are insufficient to improve the scalp and hair condition as a whole.

In addition, the existing scalp and hair-related products are often the main ingredient that shows the effect of the chemicals often cause side effects on the scalp.

Accordingly, the present inventors developed a composition containing natural products such as red ginseng, medicinal herbs, celestial organs, neck skin and pandan in optimal proportions, thereby showing excellent improvement effect on both the scalp and hair abnormal symptoms and scalp that does not cause side effects even in long-term use. And the invention of the hair composition was completed.

In the present invention, contains red ginseng, sugar, cheongung, neck skin and pandemic, hair loss prevention effect, hair growth effect, hair growth effect, wool effect, sebum overproduction inhibitory effect, antibacterial effect against dandruff, itching prevention effect, scalp and hair The present invention provides a moisturizing effect, improved flexibility of the hair, or an effect of preventing cracking, and a composition for improving the scalp and hair that does not cause side effects even when used for a long time.

The present invention provides a composition for improving the scalp and hair.

The composition of the present invention contains red ginseng, medicinal herbs, celestial organs, bark skin and panchae.

The composition of the present invention is preferably composed of 0.003 to 0.3 parts by weight of red ginseng, 0.004 to 0.4 parts by weight of sugar, 0.085 to 8.5 parts by weight of celery, 0.004 to 0.4 parts by weight of bark skin, and 0.004 to 0.4 parts by weight of lichens.

The composition of the present invention, hair loss prevention effect, hair growth effect, hair growth effect, wool effect, sebum overproduction effect, antibacterial effect against dandruff, anti-itch effect, moisturizing effect of scalp and hair, improving the flexibility of hair or preventing cracking The effect is excellent.

Hereinafter, each component contained in the composition of the present invention will be described in detail.

Red ginseng ( Panax ginseng CA Meyer) contained in the composition of the present invention contains glycosides, essential oils, oils, amino acids, alkaloids, carbohydrates, vitamins, resins, trace elements and the like in the root portion. Glycoside components of red ginseng include glycoside mixtures such as panakuilon, panaksik, panaxol, ginsenin, or panaxadiol-2-glucoside, and the like, and panaxadiol-3-glucoside such as panaxone and panaxin. Also exists.

The pharmaceutical composition ( Swertia japonica Makino, Gentianaceae) contained in the composition of the present invention contains a crystalline glycoside, swertiamarin, swersid, genthiopicroside, amarogentine, and aromaswerin, which have a bitter taste in the outpost. do. Swertiamarines are hydrolyzed to erytaurine and glucose. In addition, the drug contains oleanolic acid (about 2%), gentinsine, gentianin (0.75%), and xanthone derivatives, norwethrianin, swertianin, methylsweatinine, belidipoline, and methylbelidipoline. .

Cnidium Officinale Makino, which contains the composition of the present invention, contains 1 to 2% of essential oils in the rhizome, including kinidilide, liger tilide, neokinidlide, butyl peralide, sedonic acid, and secunolide. It contains.

Paeonia suffruticosa Andrews contained in the composition of the present invention contains the phenolic glycosides of pheonol, pheonolide, peoniflorin , benzoic acid, pheonol and the like in the root bark and neck .

Belamcanda chinensis De Candolle (Iridaceae) contained in the composition of the present invention contains the isoflavonoid glycoside belamcandine, iridine 1.5%, and toridine in the rhizome.

Hereinafter, a method for preparing the composition of the present invention will be described.

Each component of the composition of the present invention is prepared by a conventional extraction or drying method, for example, hot water extraction or organic solvent extraction, each component itself is dried to prepare a dry state, or the dried product is ground to powder form Be prepared.

Method of extracting each component of the composition of the present invention with an alcohol is as follows.

Red ginseng selects high quality raw materials, puts them in the extraction tank, and extracts them warmly three times using 70% or more ethanol. Filtration was carried out using an extraction solvent and concentrated under reduced pressure. The concentrate was sterilized to obtain a red ginseng extract.

The sugar is filtered by adding pure ethanol, injecting cold air, adding purified water to the filtrate, leaving it to stir, and filtering to remove the precipitate. After the filtrate was compressed to obtain a residue under reduced pressure, 70% ethanol solution was added and stirred to dissolve, and then further filtered if necessary to obtain a sugar extract.

The Cheongung should be washed with purified water to remove foreign substances from the surface of the raw material, followed by primary warming extraction by adding 85% ethanol to the extraction tank. 80% ethanol is added to the residue of the first extraction to carry out the second warm extraction. The primary and secondary extracts are mixed, cooled, filtered and concentrated under reduced pressure at 45 ° C until the water content is 40% or less. 5% low fructose is added to the concentrate to adjust the sugar content to 65 BRIX or more to obtain a cheonung extract.

Bark bark is obtained by adding 50% ethanol solution to the root, storing for several days at room temperature, and then stirring to separate the filtrate. The insoluble material filtered out by the filter is removed, left alone, and ethanol is removed from the filtrate in a vacuum to obtain a solid. 1,3-butylene glycol and purified water are added to the solid to dissolve to obtain a bark extract.

Pan-chae is added to the roots with a 1: 1 mixture of 1,3-butylene glycol and anhydrous ethanol, followed by extraction for several days and filtered. Purified water is added to the filtrate, followed by extraction for several days and filtered. After being left in the freezer overnight, it is left indoors for a week and filtered to obtain panchae extract.

After obtaining the extracts of each component as described above, 1 to 5 parts by weight of red ginseng, 2 to 6 parts by weight of sugar, 80 to 90 parts by weight of cheongung, 2 to 6 parts by weight of bark skin, and 2 to 6 parts by weight of lichens Prepare the composition.

The composition of the present invention further contains not only red ginseng, sugar, cheongung, bark skin and panchae but also other active ingredients having the same or similar functions, or by further containing other active ingredients having different functions from the above ingredients, It may be prepared as a cosmetic composition for scalp and hair improvement or a pharmaceutical composition for scalp and hair improvement.

In this case, the cosmetic composition or the pharmaceutical composition of the present invention contains a mixture of red ginseng, medicinal herbs, celestial organs, bark skin and panchae in 0.10 to 10.00 parts by weight.

Ingredients that may be additionally contained in the cosmetic composition or pharmaceutical composition of the present invention can be used as long as they can be directly applied to the scalp and the local surface of the hair to promote the improvement effect of the scalp and hair, specifically tyrosinase Activators, penetration enhancers, blood flow promoters, follicle inactivators or 5-reductase inhibitors, scalp nutrients, and itching inhibitors.

In particular, the tyrosinase activity promoter may be an extract of green tea, green tea extract, or the like.

Penetration accelerator and blood flow promoting agent may be specifically iris extract, Angelica extract, witch hazel extract, Myeongmyeoncho extract, Cheongung extract, chamomile extract and the like.

The blanket deactivator may be specifically clove extract, turmeric extract, sancho extract, and the like.

5-reductase inhibitors may specifically be fennel extract, licorice extract, marigold extract, aloe extract, red ginseng extract, cheongung extract, turmeric extract, Angelica extract.

Scalp nutrients specifically include one or more vitamins or vitamin precursors consisting of iron, calcium, manganese, essential amino acids, pyridoxine hydrochloride, biotin, vitamin B1, vitamin B2, vitamin B6, vitamin D and folic acid, menthol die-panthenol, polyquater Other than nium-7, tricetylmonium chloride, dimethicone / isolaures-6, cetyltrimethylammonium chloride, cetearyl alcohol, keratin, amino acid, cyclopentasiloxane / dimethicone, dimethicone / isolaures-6 And various minerals.

The anti-itch agent may be specifically a extract of extract, red ginseng extract, panchae extract, golden extract, peppermint and mixtures thereof and the like.

The cosmetic composition for the scalp and hair of the present invention may add a base component that can be blended into general scalp and hair external preparations as needed. Specific examples include dissolution aids, surfactants, moisturizers, thickeners, pH adjusters, preservatives, antioxidants, metal ion sequestrants, fungicides, anti-inflammatory agents, antimicrobial agents, solvents, colorants, or flavoring agents.

Dissolution aids may specifically be isopropyl myristate, polyethylene glycol, medium chain fatty acid triglycerides, hydrocarbons, glycols, and the like.

Anionic surfactants among the surfactants are specifically ammonium laurylsulfosuccinate, ammonium lauryl sulfate, sodium cocoyl isionate, sodium lauryl isceionate, sodium lauryl sulfate, triethanolamine lauryl sulfate, sodium la Uryl ether sulfate (1 to 3 ethylene oxides), and the like.

Among the surfactants, nonionic surfactants may specifically be polyoxyethylene alkyl ethers, polyoxyethylene fatty acid esters, polyoxyethylene, cured castor oil derivatives, fatty acid diethanolamides, glyceryl stearate, and the like.

The cationic surfactant in the surfactant may specifically be a tertiary aliphatic amine salt, alkyltrimethylammonium chloride, dialkyldimethylammonium chloride, or the like.

Among the surfactants, the amphoteric surfactant may be specifically betaine, amidebetaine type, sulfobetaine type, steartrimonium chloride, or the like.

Moisturizing agent may be specifically glycerin, propylene glycol, 1,3-butylene glycol, dipropylene glycol, sorbitol and the like.

The thickener may specifically be a water-soluble high molecular compound such as methyl cellulose, hydroxyethyl cellulose, carrageenan, carboxymethyl cellulose, hydroxymethyl cellulose and the like.

The pH adjusting agent may specifically be citric acid, sodium hydroxide, triethanolamine, sodium citrate, phosphoric acid, sodium phosphate, lactic acid and the like.

Preservatives may specifically be benzoic acid, paraoxybenzoic acid esters, mixtures of methylchloroisothiazolinone, phenoxyethanol, DMH hydantoin and the like.

Antioxidants may specifically be dibutylhydroxytoluene, ascorbic acid and the like.

Specifically, the metal ion blocking agent may be ethylenediaminetetraacetate acetate, ethylenediaminetetraacetate tetrasodium acetate, or the like.

Fungicides may specifically be chlorhexidine gluconate, quaternary ammonium salts, pyroxtonolamines, zinc pyrithione suspensions, iodopropynyl butylcarbamate, salicylic acid and the like.

The anti-inflammatory component may specifically be monoammonium glycyrrhinate, dipotassium glycyrizine, stearyl glycyrizinate, chamomile, alpha bisabolol, allantoin and mixtures thereof.

The antimicrobial component is specifically phenoxyethanol, chlorhexidine, chlorhexidine gluconate, pyroxtonolamine, ketoconazole, arnica extract, iodopropynylbutylcarbamate, benzalkonium chloride, benzenetonium chloride, benzoic acid and salts thereof, benzyl alcohol, lavender, Rosemary, salicylic acid, triclocarban, zinc pyrithione suspensions and mixtures thereof and the like.

The solvent may be specifically ethanol, purified water, Tween 20, cyclomethicone, mineral oil, dimethicone, and the like.

Colorants and flavoring agents can use the bases used in general scalp and hair preparations.

The cosmetic composition for the scalp and hair of the present invention can be prepared in any formulation that can be applied to the scalp and hair conventionally, for example, shampoo, hair treatment, hair tonic, hair pack, mixed type of shampoo and rinse. .

It is preferable to use the scalp and hair cosmetic composition of the present invention by a method of transdermal administration such as directly applying or spraying to the scalp or hair.

Meanwhile, the pharmaceutical composition for scalp and hair of the present invention may be prepared by further containing a pharmaceutically acceptable and physiologically acceptable adjuvant, and the adjuvant may include a solvent, a disintegrant, a sweetener, a binder, a coating agent, an expanding agent, Solubilizers such as lubricants, lubricants, or flavoring agents can be used.

The pharmaceutical composition for scalp and hair of the present invention may be formulated to include one or more additional pharmaceutically acceptable carriers, in addition to the active ingredients described above for administration.

Pharmaceutically acceptable carriers may be used in combination with saline, sterile water, Ringer's solution, buffered saline, dextrose solution, maltodextrin solution, glycerol, ethanol and one or more of these components, as necessary, including antioxidants, buffers, Other conventional additives such as bacteriostatic agents can be added.

In addition, the pharmaceutical compositions for scalp and hair of the present invention may be formulated into injectable formulations, pills, capsules, granules or tablets, such as aqueous solutions, suspensions, emulsions, etc. by additionally adding diluents, dispersants, surfactants, binders and lubricants. have. Furthermore, it may be preferably formulated according to each disease or component by a suitable method in the art or using a method disclosed in Remington's Pharmaceutical Science (Recent Edition), Mack Publishing Company, Easton PA.

The pharmaceutical composition for scalp and hair of the present invention is intravenous, intraarterial, intraperitoneal, intramuscular, intraarterial, intraperitoneal, sternum, transdermal, nasal, inhaled, topical, rectal, oral, ocular Administration can be in conventional manner via the intradermal or intradermal route.

The amount of the composition of the present invention can be appropriately adjusted according to the individual differences, the dosage form, the form of age, the extent of the lesion, etc., preferably used in the range of about 200 to 1000 mg per day.

The components contained in the composition of the present invention are components that have been clinically applied for a long time and demonstrated human stability, and do not cause side effects even when used for a long time.

The composition of the present invention can be usefully used as a cosmetic, pharmaceutical, or quasi-drug for improving the scalp and hair condition.

Hereinafter, preferred examples are provided to aid in understanding the present invention. However, the following examples are merely provided to more easily understand the present invention, and the contents of the present invention are not limited by the examples.

EXAMPLES Hair loss prevention, hair growth, wool, hair growth promoting effect and sebum overproduction inhibition effect by the composition of the present invention

1) Preparation of the composition of the present invention

Using the composition of the present invention, a shampoo was prepared as follows.

To prepare the composition of the present invention, red ginseng, sugar, cheongung, bark skin and panchaebu extract were prepared.

Red ginseng was selected by selecting a good raw material and added to the extraction tank, and extracted by repeating three times for 10 to 12 hours at 60 ~ 80 ℃ using more than 70% ethanol. The amount of the extraction solvent was 5-6 times the input amount, and the filtrate was obtained using a 100 micrometer filter, and it concentrated under reduced pressure at the conditions of 500-600 mmHg at 60 degreeC. The concentrate was sterilized at 80 ° C. for 2 hours, and quantitatively filled in a sterilized container to obtain a red ginseng extract.

The sugar was filtered by adding 1 kg to 15 L of pure ethanol and injecting cold air. 9 liters of purified water was added to the filtrate, and the mixture was left to stir. Then, the precipitate was filtered to remove the precipitate. After the filtrate was compressed under reduced pressure to obtain a residue, 70% ethanol solution was added, stirred to dissolve, and further filtered to obtain a saccharide extract.

The cheongung was washed with purified water to remove foreign substances from the surface of the raw material, and then extracted with warm water at 80 ℃ for 4 hours by adding 6% of 85% ethanol in the extraction tank. Four times of 80% ethanol was added to the first extraction residue, followed by warm extraction at 80 ° C for 4 hours to carry out the second extraction. The primary and secondary extracts were mixed, cooled, filtered and concentrated under reduced pressure for 4 hours until the water content was 40% or less at 45 ° C. 5% low fructose was added to the concentrate, and the sugar content was adjusted to 65 BRIX or more to obtain a cheonung extract.

Bark bark was obtained by adding 150 L of 50% ethanol solution to the root of 10 kg, storing at room temperature for 5-7 days, and stirring to separate the filtrate. The insoluble material filtered out by the filter was removed, left to stand, and ethanol was removed from the filtrate in a vacuum to obtain a solid. 50 kg of 1,3-butylene glycol and 49 kg of purified water were added to and dissolved in 1 kg of the solid, thereby obtaining the extract of neck peel.

The pan-chae was added to 4 kg of a 1: 1 mixture of 1,3-butylene glycol and anhydrous ethanol in 1 kg of the root, and then extracted and filtered for 3 days. 6 kg of purified water was added to the filtrate, followed by extraction for 3 days and filtered. After being left in the freezer overnight, it was left indoors for 1 week and filtered.

After obtaining the extracts of each component as described above, it was mixed with 3 parts by weight of red ginseng extract, 4 parts by weight of sugar extract, 85 parts by weight of cheongung extract, 4 parts by weight of bark skin extract, 4 parts by weight of panchae extract.

A shampoo composition was prepared by adding a mixture of red ginseng, medicinal herbs, cheonggung, neck skin and panchae extract, prepared in the above manner, and the other ingredients listed in Table 1.

At this time, a comparative example containing only the other ingredients in the same ratio was also prepared, without containing a mixture of red ginseng, medicinal herbs, cheonggung, bark skin and panchae extract.

Order of addition Purpose of raw material Raw material name amount Production Example Comparative example One solvent Purified water 20.75 24.96 2 Metal Ion Blocker Sodium ethylenediaminetetraacetate 0.10 0.10 3 Scalp Nutritional Supplements Diel-Pantenol 0.20 0.20 4 Moisturizer Propylene glycol 0.50 0.50 5 Thickener Polyquaternium-10 0.35 0.35 6 Surfactants Ammonium Laureth-3 Sulfate 45.00 45.00 7 Surfactants Ammonium Lauryl Sulfate 15.00 15.00 8 Surfactants Kokamido Profile 4.00 4.00 9 Scalp Nutritional Supplements Polyquaternium-7 0.30 0.30 10 pH regulator Sodium phosphate 0.20 0.05 11 Surfactants Glycol distearate 2.00 2.00 12 Surfactants Cocamide MEI 1.80 1.80 13 Surfactants Potassium cocoyl glutamate 2.00 2.00 14 Thickener Sodium chloride 0.80 0.80 15 Scalp Nutritional Supplements Tricetylmonium chloride 0.50 0.50 16 disinfectant Salicylic acid 0.10 0.10 17 disinfectant Urethral propynylbutyl carbamate 0.10 0.10 18 Scalp Nutritional Supplements Dimethicone / isolauresu-6 3.20 3.20 19 antiseptic DMH Hidantoin 0.10 0.10 20 Natural extracts Red Ginseng, Sugar, Cheongung, Peel Skin and Panchae 1.00 ㆍ 21 coloring agent Pigment 0.30 0.30 22 Flavor Spices 1.00 1.00

Shampoo of the present invention by mixing the raw materials other than the flavor and purified water of each raw material and then completely dissolved by heating to 80 ℃ stirring while stirring, adding the flavor, pigment and purified water at 40 ℃ while cooling and ending the cooling at 30 ℃ The composition was prepared.

2) hair loss prevention, hair growth, wool, hair growth promoting effect and sebum overproduction inhibition effect by the composition of the present invention

Hair loss prevention, hair growth, wool, hair growth promoting effect and sebum overproduction inhibition effect by the composition of the present invention was confirmed as follows.

The experiments were conducted on people with signs of hair loss, problems with hair growth, wool, hair growth, and excessive sebum production, which were divided into four groups according to the degree of symptoms (Table 2).

division Hair condition First group   Hair loss is more than 50% under visual evaluation, and 12 adult males in their 20s to 50s have excessive sebum production. 2nd group   Hair loss is more than 50% under visual evaluation, and 10 adult males in their 20s to 50s have excessive sebum production. Third group   Hair loss is not hair loss, but when the naked eye is a lot of hair, many fall out, sebum overproduction 10 adult men in their 20s to 50s Fourth group   20 males and 30 females from 18 to 50 years old who have healthy hair but usually lose their hair during visual evaluation.

For each group, each shampoo composition prepared in Preparation Example was used. The number of times of use was about once every 7 days, and the evaluation was conducted by surveying the effect of using each composition for an average of 4 months. The evaluation scores were summarized as 8 to 10 points when the symptoms were significantly improved, 5 to 7 points when the symptoms were improved, and 0 to 4 points when the symptoms were not changed or worsened, and the results are shown in Table 3. .

division Group using the composition of the present invention Comparative Example The group using the composition First group 2nd group Third group Fourth group First group 2nd group Third group Fourth group Hair loss prevention effect 7.8 points 8.3 points 9.7 points 8.6 points 6.4 points 7.1 points 7.9 points 7.4 points Hair growth effect 2.8 points 3.9 points 3.6 points - 2.4 points 3.5 points 3.4 points - Hair growth effect 5.4 points 6.1 points 5.6 points - 4.7 points 5.2 points 5.0 points - Wool effect 5.8 points 5.7 points 5.7 points - 4.6 points 4.9 points 4.9 points - Sebum overproduction inhibitory effect 8.4 points 8.4 points 9.0 points - 7.0 points 7.0 points 7.6 points -

As shown in Table 3, the group using the composition of the present invention was superior to the group using the comparative composition in all items such as hair loss prevention, hair growth, wool, hair growth promoting effect and sebum overproduction inhibitory effect.

Particularly in the condition of hair loss, the daily dropout rate of hair was reduced to 90-40% level.

No unusual skin irritation was found due to side effects while using the composition of the present invention.

Therefore, it can be seen that the composition of the present invention exhibits hair loss prevention, hair growth, wool, hair growth promoting effect, and sebum overproduction inhibition effect without any side effects.

Example 2 Antimicrobial and Itching Prevention Effects of the Compositions of the Present Invention against Dandruff

The antimicrobial and anti-itch effects of the composition of the present invention prepared in Example 1 against dandruff were confirmed as follows.

Experiments were performed on people with dandruff on the scalp and itching, and they were divided into four groups by symptom (Table 4).

division Hair condition First group Hair loss is more than 50% in visual evaluation and 15 adult men in their 20s to 60s with oily dandruff 2nd group Hair loss is more than 10% in visual evaluation and 15 adult men in their 20s to 60s with dry dandruff Third group 15 men and 20 women in their teens to 50s with oily dandruff with seborrheic dermatitis on their scalp. Fourth group 20 men and 20 women in their teens to 60s with healthy hair but other dandruff bacteria

For each group, each shampoo composition prepared in Preparation Example was used. The number of times of use was about once every 7 days, and the evaluation was conducted by surveying the effect of using each composition for an average of 4 months. The evaluation scores were summarized as 8 to 10 points when symptoms were significantly improved, 5 to 7 points when symptoms were improved, and 0 to 4 points when symptoms were not changed or worsened, and the results are shown in Table 5. .

division Group using the composition of the present invention Comparative Example The group using the composition First group 2nd group Third group Fourth group First group 2nd group Third group Fourth group Antibacterial Effect on Dandruff 9.3 points 8.8 points 3.5 points 5.5 points 7.8 points 8.0 points 3.0 points 4.7 points Anti-itch effect 7.0 points 7.2 points 6.1 points 6.9 points 6.1 points 6.1 points 5.2 points 5.4 points

As shown in Table 5, the group using the composition of the present invention was superior to the antibacterial and anti-itch effect against dandruff compared to the group using the composition of the comparative example.

No unusual skin irritation was found due to side effects while using the composition of the present invention.

Therefore, it can be seen that the composition of the present invention exhibits an antibacterial and anti-itch effect against dandruff without any side effects.

Example 3 Moisturizing of the scalp and hair by the composition of the present invention, improving the flexibility of the hair and preventing cracking

Moisturizing of the scalp and hair by the composition of the present invention prepared in Example 1, improved hair flexibility and the prevention of cracking was confirmed as follows.

The experiment was performed on people with dandruff on the scalp and itching, which was divided into four groups by symptom (Table 6).

division Hair condition First group 10 males in their 20s to 60s who have cracked hair, stiffness, slackness and inflexibility (more than 30% in visual evaluation) 2nd group Hair split, stiff, sloppy, and inflexible (more than 30% in visual evaluation). 5 males and 11 females in their 20s and 60s. Third group 5 men and 15 women in their 20s and 60s who are stiff, sloppy, and inflexible (more than 20% in visual evaluation) Fourth group In the visual evaluation, 15 healthy men and 20 women in their 60s, healthy hair

For each group, each shampoo composition prepared in Preparation Example was used. The number of times of use was about once every 7 days, and the evaluation was conducted by surveying the effect of using each composition for an average of 4 months. The evaluation scores were summarized as 8 to 10 points when the symptoms were significantly improved, 5 to 7 points when the symptoms were improved, and 0 to 4 points when the symptoms were not changed or worsened, and the results are shown in Table 7. .

division Group using the composition of the present invention Comparative Example The group using the composition First group 2nd group Third group Fourth group First group 2nd group Third group Fourth group Moisturizing effect 7.9 points 7.5 points 7.0 points 7.2 points 6.5 points 5.8 points 5.8 points 6.4 points Softening effect 8.7 points 8.4 points 8.8 points 8.1 points 7.0 points 6.8 points 7.2 points 7.1 points Split prevention effect 8.0 points 6.7 points 6.8 points 7.1 points 6.8 points 5.4 points 5.5 points 6.2 points

As shown in Table 7, the group using the composition of the present invention was found to be superior to the moisturizing scalp and hair, improving the flexibility of the hair and preventing cracking compared to the group using the composition of the comparative example.

In particular, the recovery effect of hair damaged by frequent perm or dry was also very good.

No unusual skin irritation was found due to side effects while using the composition of the present invention.

Therefore, it can be seen that the composition of the present invention exhibits the effect of moisturizing the scalp and hair, improving the flexibility of the hair, and preventing the splitting without any side effects.

The composition of the present invention, compared to the existing scalp and hair composition, hair loss prevention effect, hair growth effect, hair growth effect, wool effect, sebum overproduction effect, antibacterial effect against dandruff, anti-itch effect, moisturizing effect of scalp and hair, It is excellent in improving the flexibility of hair or preventing cracking.

In addition, the composition of the present invention does not cause side effects even after long-term use.

Therefore, the composition of the present invention can be usefully used in various fields such as pharmaceuticals, quasi-drugs or cosmetics for improving the scalp and hair.

Claims (5)

Cosmetic composition for improving the scalp containing red ginseng, sugar, cheongung, neck skin and panchae. The cosmetic composition for improving the scalp according to claim 1, which contains 0.003 to 0.3 parts by weight of red ginseng, 0.004 to 0.4 parts by weight of sugar, 0.085 to 8.5 parts by weight of bowels, 0.004 to 0.4 parts by weight of bark skin, and 0.004 to 0.4 parts by weight of pancreas. The cosmetic composition for improving the scalp according to claim 1 or 2, wherein the cosmetic composition exhibits at least one effect selected from a sebum overproduction inhibitory effect, an antibacterial effect against dandruff, and an anti-itch effect. delete delete