KR102114487B1 - 산형(酸型) 카르복시 메틸 셀룰로오스 및 결정 셀룰로오스를 포함하는 붕해성 입자 조성물 및 그 조성물을 포함하는 구강내 붕해 정제 - Google Patents

산형(酸型) 카르복시 메틸 셀룰로오스 및 결정 셀룰로오스를 포함하는 붕해성 입자 조성물 및 그 조성물을 포함하는 구강내 붕해 정제 Download PDF

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KR102114487B1
KR102114487B1 KR1020157009913A KR20157009913A KR102114487B1 KR 102114487 B1 KR102114487 B1 KR 102114487B1 KR 1020157009913 A KR1020157009913 A KR 1020157009913A KR 20157009913 A KR20157009913 A KR 20157009913A KR 102114487 B1 KR102114487 B1 KR 102114487B1
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particle composition
disintegrating
crystalline cellulose
carboxy methyl
composition
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KR20150056636A (ko
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타카히로 히라무라
기요시 이쿠라
새 이시카와
토모히토 오카바야시
나오히로 하시카와
테추로 모리타
키미코 이케다
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주식회사 다이셀
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Chemistry (AREA)
KR1020157009913A 2012-09-20 2013-09-13 산형(酸型) 카르복시 메틸 셀룰로오스 및 결정 셀룰로오스를 포함하는 붕해성 입자 조성물 및 그 조성물을 포함하는 구강내 붕해 정제 Active KR102114487B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012206897 2012-09-20
JPJP-P-2012-206897 2012-09-20
PCT/JP2013/074823 WO2014046035A1 (ja) 2012-09-20 2013-09-13 酸型カルボキシメチルセルロース及び結晶セルロースを含む崩壊性粒子組成物及び該組成物を含む口腔内崩壊錠剤

Publications (2)

Publication Number Publication Date
KR20150056636A KR20150056636A (ko) 2015-05-26
KR102114487B1 true KR102114487B1 (ko) 2020-05-22

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KR1020157009913A Active KR102114487B1 (ko) 2012-09-20 2013-09-13 산형(酸型) 카르복시 메틸 셀룰로오스 및 결정 셀룰로오스를 포함하는 붕해성 입자 조성물 및 그 조성물을 포함하는 구강내 붕해 정제

Country Status (8)

Country Link
US (1) US10292934B2 (https=)
EP (1) EP2898899B1 (https=)
JP (1) JP6230539B2 (https=)
KR (1) KR102114487B1 (https=)
CN (1) CN104010663B (https=)
IN (1) IN2015DN02907A (https=)
TW (1) TWI639446B (https=)
WO (1) WO2014046035A1 (https=)

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JP5996633B2 (ja) 2012-03-29 2016-09-21 株式会社ダイセル 酸型カルボキシメチルセルロースを含む崩壊性粒子組成物の製造方法、並びに、該組成物及び該組成物を含む口腔内崩壊錠剤
JP6479658B2 (ja) * 2013-07-06 2019-03-06 株式会社ダイセル 超速崩壊錠剤及びその製造方法
CN105555316B (zh) 2013-09-27 2020-07-07 株式会社大赛璐 通过二阶段的湿式制粒工序制备的崩解性颗粒组合物及含有该组合物的口腔内崩解片剂
CN105555262A (zh) * 2013-09-27 2016-05-04 株式会社大赛璐 含有崩解性颗粒组合物的口腔内崩解片剂
JP2017226600A (ja) * 2014-10-16 2017-12-28 株式会社ダイセル 超速崩壊錠剤
CN106999600B (zh) 2014-11-24 2020-11-20 株式会社大赛璐 包含粉碎乳糖或制粒乳糖的崩解性颗粒组合物
CN106999437A (zh) * 2014-12-25 2017-08-01 株式会社大赛璐 超速崩解片剂及其制备方法
TWI695722B (zh) * 2015-06-29 2020-06-11 日商大賽璐股份有限公司 固態製劑之外層用組成物及含有該外層用組成物之易服用性固態製劑
ES2607715B1 (es) 2015-10-01 2018-01-17 Solutex Na, Lcc Proceso para la preparación y estabilización de emulsiones con omega-3 mediante redes cristalinas isométricas de derivados de celulosa
JP6697874B2 (ja) * 2015-12-25 2020-05-27 日本製紙パピリア株式会社 成形材料及び成形品
KR20180102114A (ko) * 2016-01-18 2018-09-14 주식회사 다이셀 구강 내 유지형 붕해성 고형 제제, 그 제조방법, 및 상기 제조방법에 이용하는 분체 조성물
JP2019156723A (ja) * 2018-03-07 2019-09-19 大原薬品工業株式会社 圧縮成形性に優れた賦形剤を用いる、浸透膨潤型口腔内崩壊錠
JP7036856B2 (ja) * 2019-03-28 2022-03-15 日本ケミファ株式会社 口腔内崩壊錠
EP4056638A4 (en) * 2019-11-07 2022-11-30 Asahi Kasei Kabushiki Kaisha COMPOSITION OF CELLULOSE, TABLET AND ORODISPERSIBLE TABLET
WO2021099531A1 (en) 2019-11-22 2021-05-27 Biohorm, S.L. Zonisamide orodispersible tablets

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WO2009102038A1 (ja) * 2008-02-13 2009-08-20 Dainippon Sumitomo Pharma Co., Ltd. 口腔内崩壊錠

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JPH10182436A (ja) 1996-10-31 1998-07-07 Takeda Chem Ind Ltd 固形医薬製剤
JP2000273039A (ja) * 1999-01-20 2000-10-03 Taisho Pharmaceut Co Ltd 口腔内崩壊性組成物
JP2000290172A (ja) * 1999-04-09 2000-10-17 Earth Chem Corp Ltd 発泡タブレット
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JP4284017B2 (ja) * 2000-10-06 2009-06-24 武田薬品工業株式会社 固形製剤
JP4551627B2 (ja) 2003-02-28 2010-09-29 東和薬品株式会社 口腔内崩壊錠剤の製造方法
WO2007018192A1 (ja) 2005-08-10 2007-02-15 Shionogi & Co., Ltd. 口腔内崩壊錠剤
JP5123517B2 (ja) 2005-11-14 2013-01-23 帝人ファーマ株式会社 アンブロキソール口腔内速崩性錠剤
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KR20160083132A (ko) 2007-06-06 2016-07-11 바스프 에스이 급속 붕해 정제의 제조를 위한 제약 제제
WO2011019043A1 (ja) * 2009-08-11 2011-02-17 大日本住友製薬株式会社 ２種以上の粒子を含有する口腔内速崩壊錠
JP5674666B2 (ja) 2009-08-11 2015-02-25 富士化学工業株式会社 崩壊性粒子組成物及び口腔内速崩壊錠
US20110150989A1 (en) 2009-12-22 2011-06-23 Mallinkckrodt Inc. Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans
JP6073543B2 (ja) 2010-07-08 2017-02-01 沢井製薬株式会社 ロラタジン含有口腔内崩壊錠の製造方法
JP6245677B2 (ja) * 2012-01-20 2017-12-13 ニプロ株式会社 口腔内崩壊錠
JP5996633B2 (ja) 2012-03-29 2016-09-21 株式会社ダイセル 酸型カルボキシメチルセルロースを含む崩壊性粒子組成物の製造方法、並びに、該組成物及び該組成物を含む口腔内崩壊錠剤

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WO2009102038A1 (ja) * 2008-02-13 2009-08-20 Dainippon Sumitomo Pharma Co., Ltd. 口腔内崩壊錠

Also Published As

Publication number Publication date
TWI639446B (zh) 2018-11-01
CN104010663B (zh) 2021-02-19
TW201417843A (zh) 2014-05-16
KR20150056636A (ko) 2015-05-26
JPWO2014046035A1 (ja) 2016-08-18
WO2014046035A1 (ja) 2014-03-27
EP2898899B1 (en) 2019-09-11
EP2898899A4 (en) 2016-03-16
JP6230539B2 (ja) 2017-11-15
IN2015DN02907A (https=) 2015-09-11
EP2898899A1 (en) 2015-07-29
US20150238424A1 (en) 2015-08-27
CN104010663A (zh) 2014-08-27
US10292934B2 (en) 2019-05-21

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