KR102042296B1 - 신규한 비시클릭 티아졸 화합물 - Google Patents

신규한 비시클릭 티아졸 화합물 Download PDF

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Publication number
KR102042296B1
KR102042296B1 KR1020147032428A KR20147032428A KR102042296B1 KR 102042296 B1 KR102042296 B1 KR 102042296B1 KR 1020147032428 A KR1020147032428 A KR 1020147032428A KR 20147032428 A KR20147032428 A KR 20147032428A KR 102042296 B1 KR102042296 B1 KR 102042296B1
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KR
South Korea
Prior art keywords
substituted
unsubstituted
groups
group
thiazole
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Expired - Fee Related
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KR1020147032428A
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English (en)
Korean (ko)
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KR20150014931A (ko
Inventor
마사아키 사와
히데키 모리야마
데스시 야마다
미키 시타시게
유스케 가와세
유코 우노
Original Assignee
카나 바이오사이언스, 인코포레이션
고쿠리츠켕큐카이하츠호진 고쿠리츠간켕큐센타
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Application filed by 카나 바이오사이언스, 인코포레이션, 고쿠리츠켕큐카이하츠호진 고쿠리츠간켕큐센타 filed Critical 카나 바이오사이언스, 인코포레이션
Publication of KR20150014931A publication Critical patent/KR20150014931A/ko
Application granted granted Critical
Publication of KR102042296B1 publication Critical patent/KR102042296B1/ko
Expired - Fee Related legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
KR1020147032428A 2012-05-24 2013-05-22 신규한 비시클릭 티아졸 화합물 Expired - Fee Related KR102042296B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/479,396 US20130317218A1 (en) 2012-05-24 2012-05-24 Novel bicyclic thiazole compounds
US13/479,396 2012-05-24
PCT/JP2013/064960 WO2013176293A1 (en) 2012-05-24 2013-05-22 Novel bicyclic thiazole compounds

Publications (2)

Publication Number Publication Date
KR20150014931A KR20150014931A (ko) 2015-02-09
KR102042296B1 true KR102042296B1 (ko) 2019-11-07

Family

ID=48628877

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147032428A Expired - Fee Related KR102042296B1 (ko) 2012-05-24 2013-05-22 신규한 비시클릭 티아졸 화합물

Country Status (6)

Country Link
US (2) US20130317218A1 (https=)
EP (1) EP2855470B1 (https=)
JP (1) JP6095195B2 (https=)
KR (1) KR102042296B1 (https=)
CN (1) CN104321321B (https=)
WO (1) WO2013176293A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130317218A1 (en) 2012-05-24 2013-11-28 Masaaki Sawa Novel bicyclic thiazole compounds
WO2016202935A1 (en) * 2015-06-19 2016-12-22 Bayer Pharma Aktiengesellschaft Glucose transport inhibitors
JP6881309B2 (ja) * 2015-10-14 2021-06-02 日産化学株式会社 液晶配向剤、液晶配向膜、及び液晶表示素子
WO2024111626A1 (ja) * 2022-11-25 2024-05-30 カルナバイオサイエンス株式会社 新規チアゾール誘導体

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100137386A1 (en) 2008-12-01 2010-06-03 Tesshi Yamada Tnik inhibitor and the use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4038661B2 (ja) * 2002-05-21 2008-01-30 株式会社大塚製薬工場 ホスホン酸ジエステル誘導体
US8323943B2 (en) * 2008-02-21 2012-12-04 National Cancer Center Screening method for anticancer drug
US20130317218A1 (en) 2012-05-24 2013-11-28 Masaaki Sawa Novel bicyclic thiazole compounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100137386A1 (en) 2008-12-01 2010-06-03 Tesshi Yamada Tnik inhibitor and the use

Also Published As

Publication number Publication date
CN104321321A (zh) 2015-01-28
WO2013176293A1 (en) 2013-11-28
US20150133656A1 (en) 2015-05-14
EP2855470B1 (en) 2018-10-17
US9102637B2 (en) 2015-08-11
CN104321321B (zh) 2017-07-07
JP6095195B2 (ja) 2017-03-15
JP2015517453A (ja) 2015-06-22
EP2855470A1 (en) 2015-04-08
US20130317218A1 (en) 2013-11-28
KR20150014931A (ko) 2015-02-09

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