KR101941514B1 - 개선된 반감기를 가지는 변형된 항체 - Google Patents
개선된 반감기를 가지는 변형된 항체 Download PDFInfo
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- KR101941514B1 KR101941514B1 KR1020137019148A KR20137019148A KR101941514B1 KR 101941514 B1 KR101941514 B1 KR 101941514B1 KR 1020137019148 A KR1020137019148 A KR 1020137019148A KR 20137019148 A KR20137019148 A KR 20137019148A KR 101941514 B1 KR101941514 B1 KR 101941514B1
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| WO2022108148A1 (ko) * | 2020-11-18 | 2022-05-27 | 주식회사 녹십자 | 자가 항체에 대한 회피율 또는 활성이 증가된 adamts13 변이체 |
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| BR112013016235B1 (pt) * | 2010-12-22 | 2020-03-31 | Cephalon Australia Pty Ltd | Anticorpo isolado, uso de um anticorpo, ácido nucleico, célula transformada e composição farmacêutica |
| KR102096224B1 (ko) | 2011-10-28 | 2020-04-03 | 테바 파마슈티컬즈 오스트레일리아 피티와이 엘티디 | 폴리펩티드 구축물 및 이의 용도 |
| EP3722320A3 (en) | 2012-10-25 | 2020-12-30 | Bioverativ USA Inc. | Anti-complement c1s antibodies and uses thereof |
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| CA2894245C (en) * | 2012-12-17 | 2022-03-22 | Trillium Therapeutics Inc. | Treatment of cd47+ disease cells with sirp alpha-fc fusions |
| ITTO20130012A1 (it) * | 2013-01-09 | 2014-07-10 | Metheresis Translational Res S A | Nuovi frammenti anticorpali, relative composizioni ed usi |
| KR20210094669A (ko) | 2013-04-29 | 2021-07-29 | 에프. 호프만-라 로슈 아게 | 인간 fcrn-결합 변형된 항체 및 사용 방법 |
| US11117975B2 (en) | 2013-04-29 | 2021-09-14 | Teva Pharmaceuticals Australia Pty Ltd | Anti-CD38 antibodies and fusions to attenuated interferon alpha-2B |
| EP2992013B1 (en) | 2013-04-29 | 2019-12-04 | Teva Pharmaceuticals Australia Pty Ltd | Anti-cd38 antibodies and fusions to attenuated interferon alpha-2b |
| US20160068613A1 (en) | 2013-04-29 | 2016-03-10 | Hoffmann-La Roche Inc. | Fc-receptor binding modified asymmetric antibodies and methods of use |
| KR101895634B1 (ko) * | 2013-05-31 | 2018-09-05 | 한미약품 주식회사 | 변이된 힌지 영역을 포함하는 IgG4 Fc 단편 |
| BR112015032763A2 (pt) | 2013-07-05 | 2017-11-07 | H Lee Moffitt Cancer Ct & Res | cd33 solúvel para tratar síndromes mielodisplásicas (mds) |
| RS63571B9 (sr) * | 2013-09-13 | 2023-02-28 | Beigene Switzerland Gmbh | Anti-pd1 antitela i njihova primena kao terapeutska i dijagnostička sredstva |
| MX380658B (es) | 2014-01-15 | 2025-03-11 | Hoffmann La Roche | Variantes de region fc con union mejorada de la proteina a. |
| UA119352C2 (uk) | 2014-05-01 | 2019-06-10 | Тева Фармасьютикалз Острейліа Пті Лтд | Комбінація леналідоміду або помалідоміду і конструкції анти-cd38 антитіло-атенуйований інтерферон альфа-2b та спосіб лікування суб'єкта, який має cd38-експресуючу пухлину |
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| JO3537B1 (ar) | 2014-07-10 | 2020-07-05 | Bioarctic Neuroscience Ab | أجسام مضادة لييفية أولية لاميلويد بيتا الببتيد ab المحسنة |
| US10059763B2 (en) | 2014-09-03 | 2018-08-28 | Boehringer Ingelheim International Gmbh | Compound targeting IL-23A and TNF-alpha and uses thereof |
| UA125637C2 (uk) | 2014-10-29 | 2022-05-11 | Тева Фармасьютікалз Острейліа Пті Лтд | ЗЛИТИЙ ПОЛІПЕПТИД ІНТЕРФЕРОНУ <font face="Symbol">a2</font>b |
| US20160130324A1 (en) * | 2014-10-31 | 2016-05-12 | Shire Human Genetic Therapies, Inc. | C1 Inhibitor Fusion Proteins and Uses Thereof |
| NZ732073A (en) | 2014-12-08 | 2019-04-26 | 1Globe Biomedical Co Ltd | Soluble universal adcc-enhancing synthetic fusion gene and peptide technology and its use thereof |
| PL3303386T3 (pl) | 2015-06-05 | 2025-03-03 | Genentech, Inc. | Przeciwciała anty-tau i sposoby zastosowania |
| US11820807B2 (en) * | 2015-06-12 | 2023-11-21 | Ubi Pharma Inc | Immunoglobulin fusion proteins and uses thereof |
| KR102721401B1 (ko) * | 2015-06-12 | 2024-11-04 | 유비아이 파마 인크. | 이뮤노글로불린 융합 단백질 및 그의 용도 |
| US20160362473A1 (en) * | 2015-06-12 | 2016-12-15 | Ubi Pharma Inc | Immunoglobulin fusion proteins and uses thereof |
| BR112018001255A2 (pt) * | 2015-07-23 | 2018-09-11 | Boehringer Ingelheim International Gmbh | composto direcionado à il-23a e fator de ativação de células b (baff) e seus usos |
| EP3222672A1 (de) * | 2016-03-23 | 2017-09-27 | LANXESS Deutschland GmbH | Metallazopigmente |
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| KR102473898B1 (ko) | 2017-05-26 | 2022-12-07 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | 생물제약 조성물 및 관련 방법 |
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| KR20250021517A (ko) * | 2020-11-18 | 2025-02-13 | 주식회사 녹십자 | 자가 항체에 대한 회피율 또는 활성이 증가된 adamts13 변이체 |
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| PT2654790T (pt) | 2019-05-16 |
| EP2654790A1 (en) | 2013-10-30 |
| CA2824279A1 (en) | 2012-06-28 |
| ES2720136T3 (es) | 2019-07-18 |
| WO2012083370A1 (en) | 2012-06-28 |
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| EP2654790B1 (en) | 2019-02-06 |
| MX2013007392A (es) | 2013-11-01 |
| BR112013016235A2 (pt) | 2016-11-22 |
| EP2654790A4 (en) | 2014-05-28 |
| US20130281677A1 (en) | 2013-10-24 |
| EA201390923A1 (ru) | 2013-12-30 |
| AU2011349049B2 (en) | 2016-08-11 |
| JP6334669B2 (ja) | 2018-05-30 |
| KR20140003494A (ko) | 2014-01-09 |
| ZA201305123B (en) | 2014-09-25 |
| IL227081B (en) | 2018-04-30 |
| BR112013016235B1 (pt) | 2020-03-31 |
| JP2014503209A (ja) | 2014-02-13 |
| US9505826B2 (en) | 2016-11-29 |
| AU2011349049A1 (en) | 2013-05-02 |
| CN103429261A (zh) | 2013-12-04 |
| JP6147670B2 (ja) | 2017-06-14 |
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