KR101918188B1 - 동결건조를 위한 벤다무스틴 약학 조성물 - Google Patents
동결건조를 위한 벤다무스틴 약학 조성물 Download PDFInfo
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- KR101918188B1 KR101918188B1 KR1020177022494A KR20177022494A KR101918188B1 KR 101918188 B1 KR101918188 B1 KR 101918188B1 KR 1020177022494 A KR1020177022494 A KR 1020177022494A KR 20177022494 A KR20177022494 A KR 20177022494A KR 101918188 B1 KR101918188 B1 KR 101918188B1
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- vendamustine
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- lyophilized
- freeze
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Classifications
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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| PCT/US2006/001308 WO2006076620A2 (en) | 2005-01-14 | 2006-01-13 | Bendamustine pharmaceutical compositions for lyophilisation |
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| KR1020167021645A Ceased KR20160098530A (ko) | 2005-01-14 | 2006-01-13 | 동결건조를 위한 벤다무스틴 약학 조성물 |
| KR1020187014177A Ceased KR20180056804A (ko) | 2005-01-14 | 2006-01-13 | 동결건조를 위한 벤다무스틴 약학 조성물 |
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| US8436190B2 (en) | 2005-01-14 | 2013-05-07 | Cephalon, Inc. | Bendamustine pharmaceutical compositions |
| SG10201403526YA (en) | 2005-07-25 | 2014-10-30 | Emergent Product Dev Seattle | B-cell reduction using cd37-specific and cd20-specific binding molecules |
| US20090082416A1 (en) * | 2007-09-25 | 2009-03-26 | Protia, Llc | Deuterium-enriched bendamustine |
| JP5406197B2 (ja) * | 2007-10-09 | 2014-02-05 | ユーエス ワールドメッズ リミテッド ライアビリティ カンパニー | ダントロレン治療剤の送達を改善するための、共溶媒組成物および方法 |
| AR072777A1 (es) * | 2008-03-26 | 2010-09-22 | Cephalon Inc | Formas solidas de clorhidrato de bendamustina |
| ES2368700T3 (es) * | 2008-04-11 | 2011-11-21 | Emergent Product Development Seattle, Llc | Agente inmunoterapéutico para cd37 y combinación con un agente quimioterapéutico bifuncional del mismo. |
| EP2889029A1 (en) * | 2008-09-25 | 2015-07-01 | Cephalon, Inc. | Liquid formulations of bendamustine |
| WO2010056733A1 (en) * | 2008-11-13 | 2010-05-20 | Indiana University Research And Technology Corporation | Combined use of bendamustine, doxorubicin and bortezomib for the treatment of multiple myeloma |
| UA107186C2 (xx) * | 2008-12-03 | 2014-12-10 | Тверді форми дозування бендамустину | |
| NZ592970A (en) * | 2008-12-03 | 2013-05-31 | Astellas Deutschland Gmbh | Oral dosage forms of bendamustine |
| US8076366B2 (en) * | 2009-01-15 | 2011-12-13 | Cephalon, Inc. | Forms of bendamustine free base |
| SI2389375T1 (sl) | 2009-01-23 | 2015-11-30 | Euro-Celtique S.A. | Derivati hidroksamske kisline |
| CA2753641C (en) | 2009-02-25 | 2014-09-16 | Supratek Pharma, Inc. | Bendamustine cyclopolysaccharide compositions |
| EP2424506A1 (en) * | 2009-04-28 | 2012-03-07 | Cephalon, Inc. | Oral formulations of bendamustine |
| WO2010144675A1 (en) | 2009-06-10 | 2010-12-16 | Plus Chemicals Sa | Polymorphs of bendamustine hcl and processes for preparation thereof |
| US8389558B2 (en) * | 2009-07-20 | 2013-03-05 | Supratek Pharma Inc. | Bendamustine amphiphilic anionic compositions |
| US20110015245A1 (en) * | 2009-07-20 | 2011-01-20 | Valery Alakhov | Bendamustine amphiphilic cationic compositions |
| HUE054836T2 (hu) * | 2010-01-28 | 2021-10-28 | Eagle Pharmaceuticals Inc | Bendamusztin kiszerelései |
| WO2011103150A2 (en) * | 2010-02-18 | 2011-08-25 | Cephalon, Inc. | Lyophilized preparations of bendamustine |
| JO3659B1 (ar) * | 2010-06-02 | 2020-08-27 | Astellas Deutschland Gmbh | أشكال جرعات بينداموستين عن طريق الفم وإستخداماته العلاجية |
| JP6209446B2 (ja) * | 2010-06-02 | 2017-10-04 | アステラス ドイチュランド ゲゼルシャフト ミット ベシュレンクテル ハフツング | ベンダムスチンの経口投与形 |
| CN103052407A (zh) * | 2010-07-13 | 2013-04-17 | 赛福伦公司 | 苯达莫司汀的改进灭菌方法 |
| US8383663B2 (en) | 2010-07-19 | 2013-02-26 | Supratek Pharma Inc. | Bendamustine anionic-catioinic cyclopolysaccharide compositions |
| WO2012103226A2 (en) * | 2011-01-25 | 2012-08-02 | Dr. Reddy's Laboratories Ltd. | Bendamustine formulations |
| WO2012109429A2 (en) * | 2011-02-09 | 2012-08-16 | Glaxosmithkline Llc | Lyophilized formulations |
| US20120237492A1 (en) | 2011-02-18 | 2012-09-20 | Kythera Biopharmaceuticals, Inc. | Treatment of submental fat |
| KR101892788B1 (ko) * | 2011-09-13 | 2018-08-28 | 파마싸이클릭스 엘엘씨 | 벤다무스틴과 조합된 히스톤 디아세틸라제 억제제의 제제 및 그의 용도 |
| EP2760842B1 (en) | 2011-09-26 | 2016-11-16 | Fresenius Kabi Oncology Ltd | An improved process for the preparation of bendamustine hydrochloride |
| WO2013102920A1 (en) | 2011-11-18 | 2013-07-11 | Astron Research Limited | Stable lyophilized formulation of bendamustine |
| US20130210878A1 (en) * | 2012-01-24 | 2013-08-15 | Innopharma, Inc. | Bendamustine compositions and methods therefore |
| AR092790A1 (es) * | 2012-02-01 | 2015-05-06 | Euro Celtique Sa | Derivados bencimidazolicos del acido hidroxamico |
| US9872873B2 (en) | 2012-02-06 | 2018-01-23 | Fresenius Kabi Oncology Limited | Process for preparing stable pharmaceutical compositions of compounds susceptible to hydrolysis |
| JP2015506989A (ja) * | 2012-02-14 | 2015-03-05 | イーグル・ファーマシューティカルズ・インコーポレーテッド | ベンダムスチン製剤 |
| HRP20240056T1 (hr) | 2012-03-20 | 2024-03-29 | Eagle Pharmaceuticals, Inc. | Formulacije bendamustina |
| JP6224064B2 (ja) | 2012-03-20 | 2017-11-01 | イーグル・ファーマシューティカルズ・インコーポレーテッド | 低減された投与容量を必要とする患者におけるベンダムスチン応答性症状の治療方法 |
| WO2013148919A1 (en) | 2012-03-30 | 2013-10-03 | The Regents Of The University Of Colorado, A Body Corporate | Treatment of multiple myeloma |
| US20230241218A1 (en) * | 2012-07-10 | 2023-08-03 | Eagle Pharmaceuticals, Inc. | Formulations of bendamustine |
| US9801859B2 (en) * | 2012-09-18 | 2017-10-31 | Innopharma Licensing, Llc | Bendamustine formulations |
| EP2917183A1 (en) * | 2012-11-12 | 2015-09-16 | Ignyta, Inc. | Bendamustine derivatives and methods of using same |
| PL2732811T3 (pl) | 2012-11-19 | 2016-05-31 | Oncotec Pharma Produktion Gmbh | Proces otrzymywania kompozycji liofilizowanej |
| CN103860482B (zh) * | 2012-12-12 | 2016-08-24 | 海口市制药厂有限公司 | 一种盐酸苯达莫司汀冻干粉针剂的制备方法、其产品及用途 |
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| WO2014170769A2 (en) * | 2013-04-15 | 2014-10-23 | Shilpa Medicare Limited | Bendamustine lyophilized pharmaceutical compositions |
| ITMI20131013A1 (it) * | 2013-06-19 | 2014-12-20 | Chemi Spa | Formulazioni liofilizzate di bendamustina cloridrato |
| JP2016153374A (ja) * | 2013-06-25 | 2016-08-25 | シンバイオ製薬株式会社 | 炎症性疾患を治療又は予防するための医薬組成物 |
| CN103351347A (zh) * | 2013-07-29 | 2013-10-16 | 东南大学 | 盐酸苯达莫司汀杂质dce的制备方法 |
| CN109953954A (zh) * | 2013-08-27 | 2019-07-02 | V·沃道里斯 | 苯达莫司汀医药组合物 |
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