KR101891144B1 - Lfa-1 저해제 제형 - Google Patents

Lfa-1 저해제 제형 Download PDF

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Publication number
KR101891144B1
KR101891144B1 KR1020157019352A KR20157019352A KR101891144B1 KR 101891144 B1 KR101891144 B1 KR 101891144B1 KR 1020157019352 A KR1020157019352 A KR 1020157019352A KR 20157019352 A KR20157019352 A KR 20157019352A KR 101891144 B1 KR101891144 B1 KR 101891144B1
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composition
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Korean (ko)
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KR20150100763A (ko
Inventor
메리 뉴먼
윌리엄 훈케
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에스에이알코드 바이오사이언스 인코포레이티드
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50979140&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR101891144(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 에스에이알코드 바이오사이언스 인코포레이티드 filed Critical 에스에이알코드 바이오사이언스 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020157019352A 2012-12-19 2013-12-18 Lfa-1 저해제 제형 Active KR101891144B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261739609P 2012-12-19 2012-12-19
US61/739,609 2012-12-19
US201361758147P 2013-01-29 2013-01-29
US61/758,147 2013-01-29
PCT/US2013/076041 WO2014100135A1 (en) 2012-12-19 2013-12-18 Lfa-1 inhibitor formulations

Publications (2)

Publication Number Publication Date
KR20150100763A KR20150100763A (ko) 2015-09-02
KR101891144B1 true KR101891144B1 (ko) 2018-08-23

Family

ID=50979140

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157019352A Active KR101891144B1 (ko) 2012-12-19 2013-12-18 Lfa-1 저해제 제형

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US (2) US11058677B2 (enExample)
EP (2) EP3827823A1 (enExample)
JP (1) JP6373867B2 (enExample)
KR (1) KR101891144B1 (enExample)
CN (1) CN104955453B (enExample)
AU (1) AU2013361579B2 (enExample)
BR (1) BR112015014367B1 (enExample)
CA (1) CA2894170C (enExample)
DK (1) DK2934510T3 (enExample)
EA (2) EA201791321A1 (enExample)
ES (1) ES2846724T3 (enExample)
HU (1) HUE052299T2 (enExample)
IL (1) IL239490B (enExample)
MX (2) MX391620B (enExample)
NZ (1) NZ708821A (enExample)
PL (1) PL2934510T3 (enExample)
PT (1) PT2934510T (enExample)
SI (1) SI2934510T1 (enExample)
WO (1) WO2014100135A1 (enExample)
ZA (2) ZA201504404B (enExample)

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CN106995439B (zh) * 2016-01-26 2019-09-20 镇江圣安医药有限公司 氘取代3-(甲磺酰基)-l-苯丙氨酸衍生物及其药物组合物、药物制剂和用途
WO2019171260A1 (en) * 2018-03-09 2019-09-12 Mankind Pharma Ltd. Pharmaceutical composition of lifitegrast
JP7700045B2 (ja) * 2019-04-18 2025-06-30 アズーラ オフサルミックス エルティーディー． 眼障害を処置するための化合物および方法
EP3842032A1 (en) 2019-12-24 2021-06-30 Warszawskie Zaklady Farmaceutyczne Polfa S.A. A pharmaceutical formulation
CN116635032A (zh) * 2020-10-21 2023-08-22 阿祖拉眼科有限公司 用于治疗眼部病症的化合物和方法
CN116211796A (zh) * 2022-12-30 2023-06-06 新领先(重庆)医药科技有限公司 一种立他司特滴眼液及其制备方法
KR20240109779A (ko) * 2023-01-05 2024-07-12 주식회사 종근당 리피테그라스트와 토코페롤을 함유하는 건성안 예방 또는 치료용 약제학적 조성물
KR20250033790A (ko) 2023-09-01 2025-03-10 주식회사 와이에스생명과학 리피테그라스트 함유 점안 조성물
WO2025093739A1 (en) 2023-11-02 2025-05-08 Novaliq Gmbh Semifluorinated alkane compositions comprising lifitegrast
US20250161294A1 (en) * 2023-11-17 2025-05-22 Bausch + Lomb Ireland Limited Compositions and methods for treatment of ocular disorders
CN117771174B (zh) * 2023-12-29 2025-07-29 鲁南贝特制药有限公司 一种立他司特滴眼液及其制备方法

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WO1993023010A1 (en) 1992-05-13 1993-11-25 Sandoz Ltd. Ophthalmic compositions containing a cyclosporin
US20060073172A1 (en) 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure
US20090298869A1 (en) * 2008-04-15 2009-12-03 John Burnier Crystalline pharmaceutical and methods of preparation and use thereof
WO2012100109A2 (en) * 2011-01-20 2012-07-26 Advanced Vision Research, Inc. Therapeutic eye drop comprising doxycycline and a stabilizer

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US5429819A (en) * 1992-10-14 1995-07-04 Matsushita Electric Industrial Co., Ltd. Antiviral composition
IT1277707B1 (it) * 1995-12-22 1997-11-11 Chemedica Sa Formulazione oftalmica a base di ialuronato di sodio per uso nella chirurgia oculare
JP4138910B2 (ja) * 1997-07-02 2008-08-27 帝國製薬株式会社 経皮吸収性が良好で且つ皮膚刺激性の少ない塩酸アゼラスチン含有経皮製剤
RU2149611C1 (ru) * 1998-04-06 2000-05-27 Московская медицинская академия им. И.М. Сеченова Капли для лечения воспалительных заболеваний глаз (варианты)
DE19954516A1 (de) * 1999-11-12 2001-05-17 Boehringer Ingelheim Int Epinastin-haltige Lösungen
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KR20110001103A (ko) 2009-06-29 2011-01-06 에스케이케미칼주식회사 보관 안정성이 향상된 톨테로딘 함유 경피 투여 조성물
PH12012501098A1 (en) * 2009-11-23 2014-10-14 Allergan Inc 7-[3,5-dihydroxy-2- (3-hydroxy-5-phenyl-pent-1-enyl)- cyclopentyl]-n-ethyl-hept-5-enamide (bimatoprost) in crystalline form ii, methods for preparation, and methods for use thereof
BR112013021048A2 (pt) * 2011-02-18 2016-10-18 M S Appasmy Associates composição oftálmica para permitir dilatação de pupilas
CN103764150A (zh) * 2011-06-29 2014-04-30 阿勒根公司 阿卡他定在治疗荨麻疹中的用途
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WO1993023010A1 (en) 1992-05-13 1993-11-25 Sandoz Ltd. Ophthalmic compositions containing a cyclosporin
US20060073172A1 (en) 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure
US20090298869A1 (en) * 2008-04-15 2009-12-03 John Burnier Crystalline pharmaceutical and methods of preparation and use thereof
WO2012100109A2 (en) * 2011-01-20 2012-07-26 Advanced Vision Research, Inc. Therapeutic eye drop comprising doxycycline and a stabilizer

Also Published As

Publication number Publication date
AU2013361579B2 (en) 2018-05-24
IL239490B (en) 2018-12-31
BR112015014367A2 (pt) 2017-07-11
JP2016503058A (ja) 2016-02-01
NZ708821A (en) 2020-03-27
MX2019012375A (es) 2020-01-20
EA201591180A1 (ru) 2015-12-30
CA2894170C (en) 2021-08-10
KR20150100763A (ko) 2015-09-02
ZA201504404B (en) 2020-01-29
MX391620B (es) 2025-03-19
PT2934510T (pt) 2021-01-13
ZA201608069B (en) 2017-11-29
US20150320737A1 (en) 2015-11-12
DK2934510T3 (da) 2021-01-25
HK1214536A1 (zh) 2016-07-29
HUE052299T2 (hu) 2021-04-28
SI2934510T1 (sl) 2021-02-26
MX368876B (es) 2019-10-21
CA2894170A1 (en) 2014-06-26
JP6373867B2 (ja) 2018-08-15
CN104955453B (zh) 2018-09-18
IL239490A0 (en) 2015-08-31
EP2934510A1 (en) 2015-10-28
US20220000859A1 (en) 2022-01-06
MX2015007540A (es) 2016-04-13
ES2846724T3 (es) 2021-07-29
CN104955453A (zh) 2015-09-30
EA201791321A1 (ru) 2018-04-30
EP3827823A1 (en) 2021-06-02
EP2934510A4 (en) 2016-08-17
HK1214963A1 (en) 2016-08-12
AU2013361579A1 (en) 2015-06-18
EP2934510B1 (en) 2020-10-28
US11058677B2 (en) 2021-07-13
PL2934510T3 (pl) 2021-07-05
EA028008B1 (ru) 2017-09-29
BR112015014367B1 (pt) 2022-11-22
WO2014100135A1 (en) 2014-06-26

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