KR101842309B1 - 활성물질을 투여하기 위한 경피용 치료학적 시스템 - Google Patents

활성물질을 투여하기 위한 경피용 치료학적 시스템 Download PDF

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Publication number
KR101842309B1
KR101842309B1 KR1020137016047A KR20137016047A KR101842309B1 KR 101842309 B1 KR101842309 B1 KR 101842309B1 KR 1020137016047 A KR1020137016047 A KR 1020137016047A KR 20137016047 A KR20137016047 A KR 20137016047A KR 101842309 B1 KR101842309 B1 KR 101842309B1
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layer
therapeutic system
transdermal therapeutic
active material
polymer
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Korean (ko)
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KR20130129988A (ko
Inventor
브리타 랑거
비요른 스츄라드
하이케 프린츠
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루예 파마 아게
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020137016047A 2010-12-14 2011-12-14 활성물질을 투여하기 위한 경피용 치료학적 시스템 Active KR101842309B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10194968.3 2010-12-14
EP10194968.3A EP2468274B1 (de) 2010-12-14 2010-12-14 Transdermales therapeutisches System zur Verabreichung eines Wirkstoffs
PCT/EP2011/072812 WO2012080365A1 (de) 2010-12-14 2011-12-14 Transdermales therapeutisches system zur verabreichung eines wirkstoffs

Publications (2)

Publication Number Publication Date
KR20130129988A KR20130129988A (ko) 2013-11-29
KR101842309B1 true KR101842309B1 (ko) 2018-03-26

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KR1020137016047A Active KR101842309B1 (ko) 2010-12-14 2011-12-14 활성물질을 투여하기 위한 경피용 치료학적 시스템

Country Status (25)

Country Link
US (2) US10660863B2 (https=)
EP (2) EP2468274B1 (https=)
JP (1) JP6043296B2 (https=)
KR (1) KR101842309B1 (https=)
CN (3) CN113244199A (https=)
AU (2) AU2011343363B2 (https=)
BR (1) BR112013014616B1 (https=)
CA (2) CA2817461C (https=)
CY (2) CY1116638T1 (https=)
DK (2) DK2468274T3 (https=)
EA (1) EA026520B1 (https=)
ES (2) ES2545094T3 (https=)
HK (1) HK1243336A1 (https=)
HR (2) HRP20201880T1 (https=)
HU (2) HUE027916T2 (https=)
LT (1) LT2651410T (https=)
MX (1) MX345344B (https=)
MY (1) MY183873A (https=)
PL (2) PL2468274T3 (https=)
PT (2) PT2468274E (https=)
RS (2) RS54173B1 (https=)
SI (2) SI2468274T1 (https=)
SM (2) SMT202000638T1 (https=)
WO (1) WO2012080365A1 (https=)
ZA (1) ZA201303965B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200025883A (ko) 2018-08-31 2020-03-10 에스케이케미칼 주식회사 장기 투여용 리바스티그민 패취
KR20200025888A (ko) 2018-08-31 2020-03-10 에스케이케미칼 주식회사 장기 투여용 리바스티그민 패취

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DE102012000369A1 (de) * 2012-01-11 2013-07-11 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System mit Cholinesterase-Hemmer
DE102012016317A1 (de) 2012-08-14 2014-02-20 Jenabatteries GmbH Redox-Flow-Zelle zur Speicherung elektrischer Energie
US20150196515A1 (en) * 2012-08-15 2015-07-16 Dow Coming Corporation Multi-Layer Drug Delivery System
WO2014111790A2 (en) * 2013-01-15 2014-07-24 Zydus Technologies Limited Stable transdermal pharmaceutical drug delivery system comprising rivastigmine
US20240082065A1 (en) * 2016-07-08 2024-03-14 Moteah Williams Waterproof and transparent wound barrier and method of manufacturing same
JP6864968B2 (ja) 2016-08-22 2021-04-28 救急薬品工業株式会社 貼付剤
US12290501B2 (en) * 2017-07-19 2025-05-06 Teikoku Seiyaku Co., Ltd. Rivastigmine-containing transdermal absorption preparation
DE102018120506A1 (de) * 2017-10-20 2019-04-25 Amw Gmbh Stabilisiertes transdermales Darreichungssystem
DE102017127433A1 (de) * 2017-11-21 2019-05-23 Lts Lohmann Therapie-Systeme Ag TTS auf Basis von klebenden Weichmacher-Polymer-Matrices
JP2021517572A (ja) * 2018-03-13 2021-07-26 エルテーエス ローマン テラピー−ジステーメ アーゲー シリコーンアクリルハイブリッドポリマーを含む経皮治療システム
JP7170285B2 (ja) * 2018-05-17 2022-11-14 パナソニックＩｐマネジメント株式会社 生体貼付け用選択透過膜、経皮吸収キットおよび美容方法
ES2923891T3 (es) 2018-08-08 2022-10-03 Danapak Flexibles As Películas y láminas mejoradas para usarse en el envase de compuestos reactivos
CN114007595A (zh) * 2019-07-09 2022-02-01 罗曼治疗系统股份公司 包括包含丙烯酸类聚合物的含活性剂层和包含硅酮凝胶粘合剂的皮肤接触层的透皮治疗系统
CN113616625B (zh) * 2021-08-26 2023-05-30 大连科翔科技开发有限公司 一种卡巴拉汀的长效透皮贴剂
DE102021128912A1 (de) * 2021-11-05 2023-05-11 Lts Lohmann Therapie-Systeme Ag. Okklusives pflaster mit flexibler backing

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AU3247193A (en) * 1992-08-25 1994-03-15 Cygnus Therapeutic Systems Printed transdermal drug delivery device
JPH0912448A (ja) * 1995-04-28 1997-01-14 Read Chem Kk 薬物放出制御型経皮吸収製剤
GB9800526D0 (en) * 1998-01-12 1998-03-11 Ciba Geigy Ag Organic compounds
US6348210B1 (en) * 1998-11-13 2002-02-19 Alza Corporation Methods for transdermal drug administration
DE19918106A1 (de) * 1999-04-22 2000-10-26 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern
DE10033853A1 (de) 2000-07-12 2002-01-31 Hexal Ag Transdermales therapeutisches System mit hochdispersem Siliziumdioxid
DE10103860B4 (de) * 2001-01-30 2004-12-23 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System für die Verabreichung carboxylgruppenhaltiger, nichtsteroidaler Antiphlogistika, sowie Verfahren zu seiner Herstellung
DE10141650C1 (de) * 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
DE10141652B4 (de) 2001-08-24 2011-04-07 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung
US8252320B2 (en) 2004-10-21 2012-08-28 Durect Corporation Transdermal delivery system for sufentanil
US8246977B2 (en) * 2004-10-21 2012-08-21 Durect Corporation Transdermal delivery systems
TWI389709B (zh) * 2005-12-01 2013-03-21 Novartis Ag 經皮治療系統
WO2007076862A1 (en) * 2005-12-30 2007-07-12 Coloplast A/S A layered adhesive construct having a mouldable layer as skin contact surface
CN101304735A (zh) * 2006-01-12 2008-11-12 Lts勒曼治疗系统股份公司 用于挥发性和/或热不稳定的物质的经皮治疗体系
BRPI0621655A2 (pt) 2006-05-08 2011-12-20 Teikoku Seiyaku Kk preparação para a absorção percutánea de uma droga antidemência básica
US9248104B2 (en) 2006-08-17 2016-02-02 Core Tech Solutions, Inc. Transdermal methods and systems for treating Alzheimer's disease
DE102006054731B4 (de) * 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie
US20100292660A1 (en) 2007-07-10 2010-11-18 Agis Kydonieus Dermal delivery device with ultrasonic weld
JP5546013B2 (ja) * 2008-02-27 2014-07-09 久光製薬株式会社 貼付剤及び包装体
US20090291127A1 (en) * 2008-05-21 2009-11-26 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
JP2010126450A (ja) * 2008-11-25 2010-06-10 Lintec Corp 経皮吸収貼付剤
ES2670227T3 (es) * 2009-12-22 2018-05-29 Luye Pharma Ag Sistema terapéutico transdérmico para la administración de rivastigmina o sus derivados

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200025883A (ko) 2018-08-31 2020-03-10 에스케이케미칼 주식회사 장기 투여용 리바스티그민 패취
KR20200025888A (ko) 2018-08-31 2020-03-10 에스케이케미칼 주식회사 장기 투여용 리바스티그민 패취
US12318360B2 (en) 2018-08-31 2025-06-03 Sk Chemicals Co., Ltd. Rivastigmine patch for long-term administration

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MX2013005581A (es) 2013-08-26
RS61155B1 (sr) 2020-12-31
US20200289426A1 (en) 2020-09-17
ZA201303965B (en) 2014-09-25
EA026520B1 (ru) 2017-04-28
CA2817461A1 (en) 2012-06-21
SMT202000638T1 (it) 2021-01-05
SI2468274T1 (sl) 2015-10-30
BR112013014616B1 (pt) 2021-12-21
HRP20201880T1 (hr) 2021-02-05
CA3065240A1 (en) 2012-06-21
AU2011343363A1 (en) 2013-06-20
RS54173B1 (sr) 2015-12-31
PL2651410T3 (pl) 2021-03-08
JP2014503523A (ja) 2014-02-13
CY1116638T1 (el) 2017-03-15
EP2651410A1 (de) 2013-10-23
EP2651410B1 (de) 2020-10-14
PT2468274E (pt) 2015-09-21
HUE052137T2 (hu) 2021-04-28
EP2468274B1 (de) 2015-07-01
MX345344B (es) 2017-01-26
PT2651410T (pt) 2020-12-15
DK2651410T3 (da) 2020-11-02
JP6043296B2 (ja) 2016-12-14
CA3065240C (en) 2022-02-15
AU2017213569A1 (en) 2017-08-31
EP2468274A1 (de) 2012-06-27
ES2545094T3 (es) 2015-09-08
DK2468274T3 (en) 2015-08-31
BR112013014616A2 (pt) 2016-09-20
HRP20150881T1 (hr) 2015-09-25
US10660863B2 (en) 2020-05-26
MY183873A (en) 2021-03-17
CY1123712T1 (el) 2022-03-24
HK1243336A1 (zh) 2018-07-13
SMT201500184B (it) 2015-09-07
ES2836483T3 (es) 2021-06-25
WO2012080365A1 (de) 2012-06-21
KR20130129988A (ko) 2013-11-29
PL2468274T3 (pl) 2015-11-30
SI2651410T1 (sl) 2021-01-29
HUE027916T2 (en) 2016-11-28
LT2651410T (lt) 2020-12-28
AU2017213569B2 (en) 2019-04-11
US20140323996A1 (en) 2014-10-30
EA201300704A1 (ru) 2014-01-30
CN103269698B (zh) 2017-07-14
AU2011343363B2 (en) 2017-06-08
CN107412202A (zh) 2017-12-01
CA2817461C (en) 2020-02-25
CN113244199A (zh) 2021-08-13
CN103269698A (zh) 2013-08-28

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