KR101839665B1 - 심혈관 질병의 치료를 위한 경구 제제 - Google Patents

심혈관 질병의 치료를 위한 경구 제제 Download PDF

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Publication number
KR101839665B1
KR101839665B1 KR1020157033956A KR20157033956A KR101839665B1 KR 101839665 B1 KR101839665 B1 KR 101839665B1 KR 1020157033956 A KR1020157033956 A KR 1020157033956A KR 20157033956 A KR20157033956 A KR 20157033956A KR 101839665 B1 KR101839665 B1 KR 101839665B1
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KR
South Korea
Prior art keywords
acetylsalicylic acid
tablet
pharmaceutical formulation
formulation according
coating
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1020157033956A
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English (en)
Korean (ko)
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KR20160014622A (ko
Inventor
파블로 마르틴 산츠
하비에르 우르바노 후르타도
Original Assignee
페레르 인터내쇼날 에스.에이.
푼다시온 센트로 나시오날 드 인베스티가시오네스 카르디오바스쿨라레스 카를로스 Ⅲ
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48569993&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR101839665(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 페레르 인터내쇼날 에스.에이., 푼다시온 센트로 나시오날 드 인베스티가시오네스 카르디오바스쿨라레스 카를로스 Ⅲ filed Critical 페레르 인터내쇼날 에스.에이.
Publication of KR20160014622A publication Critical patent/KR20160014622A/ko
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Publication of KR101839665B1 publication Critical patent/KR101839665B1/ko
Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020157033956A 2013-06-06 2014-06-05 심혈관 질병의 치료를 위한 경구 제제 Expired - Fee Related KR101839665B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13170909.9A EP2810644A1 (en) 2013-06-06 2013-06-06 Oral formulation for the treatment of cardiovascular diseases
EP13170909.9 2013-06-06
PCT/EP2014/061735 WO2014195421A1 (en) 2013-06-06 2014-06-05 Oral formulation for the treatment of cardiovascular diseases

Publications (2)

Publication Number Publication Date
KR20160014622A KR20160014622A (ko) 2016-02-11
KR101839665B1 true KR101839665B1 (ko) 2018-03-16

Family

ID=48569993

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157033956A Expired - Fee Related KR101839665B1 (ko) 2013-06-06 2014-06-05 심혈관 질병의 치료를 위한 경구 제제

Country Status (42)

Country Link
US (1) US10617699B2 (https=)
EP (3) EP2810644A1 (https=)
JP (1) JP6151854B2 (https=)
KR (1) KR101839665B1 (https=)
CN (2) CN104224804A (https=)
AP (1) AP2015008882A0 (https=)
AR (1) AR096350A1 (https=)
AU (1) AU2014276883B2 (https=)
BR (1) BR112015030350B1 (https=)
CA (1) CA2912350C (https=)
CL (1) CL2015003561A1 (https=)
CR (1) CR20150635A (https=)
CU (1) CU24326B1 (https=)
CY (1) CY1118766T1 (https=)
DK (1) DK2986281T3 (https=)
DO (1) DOP2015000296A (https=)
EA (1) EA028969B1 (https=)
EC (1) ECSP15050273A (https=)
ES (1) ES2620078T3 (https=)
GE (1) GEP201706743B (https=)
HK (1) HK1204562A1 (https=)
HU (1) HUE033458T2 (https=)
IL (1) IL242569B (https=)
MA (1) MA38699B1 (https=)
MD (1) MD4475C1 (https=)
MX (1) MX347801B (https=)
MY (1) MY181272A (https=)
NI (1) NI201500171A (https=)
NZ (1) NZ714707A (https=)
PE (1) PE20160051A1 (https=)
PH (1) PH12015502706B1 (https=)
PL (1) PL2986281T3 (https=)
PT (1) PT2986281T (https=)
RS (1) RS55786B1 (https=)
SA (1) SA515370243B1 (https=)
SG (1) SG11201509353QA (https=)
SI (1) SI2986281T1 (https=)
TN (1) TN2015000501A1 (https=)
TW (1) TWI630928B (https=)
UA (1) UA113806C2 (https=)
WO (1) WO2014195421A1 (https=)
ZA (1) ZA201508452B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
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CN107530292B (zh) * 2015-04-16 2022-11-01 诺华股份有限公司 瑞博西尼片剂
CN111135149B (zh) * 2018-11-04 2021-05-11 张家港市中医医院 一种瑞舒伐他汀钙片及其制备方法
CN110693929A (zh) * 2019-09-09 2020-01-17 安徽中医药大学 复方药物组份在治疗脑梗死恢复期中的应用
PL4299063T3 (pl) * 2022-06-30 2024-06-10 Ferrer Internacional, S.A. Kapsułki doustne zawierające tabletki atorwastatyny wykazujące odpowiedni profil rozpuszczania i biodostępność
MX2024011227A (es) 2024-09-12 2026-04-01 Laboratorios Silanes S A De C V Composicion farmaceutica que comprende rosuvastatina y acido acetilsalicilico, proceso de preparacion y usos de la misma

Citations (1)

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WO1999047123A1 (en) * 1998-03-18 1999-09-23 Bristol-Myers Squibb Company Pharmaceutical composition containing a statin and aspirin

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MY119161A (en) 1994-04-18 2005-04-30 Novartis Ag Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities
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WO1999047123A1 (en) * 1998-03-18 1999-09-23 Bristol-Myers Squibb Company Pharmaceutical composition containing a statin and aspirin

Also Published As

Publication number Publication date
AU2014276883B2 (en) 2017-04-20
ES2620078T3 (es) 2017-06-27
AU2014276883A1 (en) 2015-11-26
CR20150635A (es) 2016-06-10
CU20150173A7 (es) 2016-06-29
JP2016520135A (ja) 2016-07-11
PH12015502706A1 (en) 2016-03-14
AP2015008882A0 (en) 2015-11-30
WO2014195421A1 (en) 2014-12-11
RS55786B1 (sr) 2017-07-31
AR096350A1 (es) 2015-12-23
MD4475B1 (ro) 2017-04-30
CU24326B1 (es) 2018-03-13
TN2015000501A1 (en) 2017-04-06
HK1204562A1 (en) 2015-11-27
CA2912350A1 (en) 2014-12-11
GEP201706743B (en) 2017-09-25
CA2912350C (en) 2017-04-04
MX2015015753A (es) 2016-08-03
DK2986281T3 (en) 2017-04-03
MX347801B (es) 2017-05-15
DOP2015000296A (es) 2016-12-30
SA515370243B1 (ar) 2016-09-19
EP2810644A1 (en) 2014-12-10
US10617699B2 (en) 2020-04-14
PH12015502706B1 (en) 2016-03-14
KR20160014622A (ko) 2016-02-11
SG11201509353QA (en) 2015-12-30
ZA201508452B (en) 2017-02-22
MD4475C1 (ro) 2017-11-30
PT2986281T (pt) 2017-03-29
CL2015003561A1 (es) 2016-06-10
CN104224804A (zh) 2014-12-24
MA38699B1 (fr) 2017-09-29
HUE033458T2 (en) 2017-12-28
BR112015030350B1 (pt) 2022-11-29
EP2986281B1 (en) 2016-12-21
PE20160051A1 (es) 2016-01-25
TWI630928B (zh) 2018-08-01
EA201600012A1 (ru) 2016-07-29
NI201500171A (es) 2019-05-07
BR112015030350A2 (pt) 2017-07-25
PL2986281T3 (pl) 2017-06-30
JP6151854B2 (ja) 2017-06-21
SI2986281T1 (sl) 2017-07-31
TW201536357A (zh) 2015-10-01
CN113143888A (zh) 2021-07-23
NZ714707A (en) 2019-04-26
EP3175849A1 (en) 2017-06-07
CY1118766T1 (el) 2017-07-12
IL242569B (en) 2018-12-31
EA028969B1 (ru) 2018-01-31
ECSP15050273A (es) 2017-07-31
UA113806C2 (xx) 2017-03-10
MA38699A1 (fr) 2017-01-31
MY181272A (en) 2020-12-21
EP2986281A1 (en) 2016-02-24
MD20160001A2 (ro) 2016-05-31
US20160106763A1 (en) 2016-04-21

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