KR101773506B1 - Ｍｕｃ1 항체 - Google Patents
Ｍｕｃ1 항체 Download PDFInfo
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- KR101773506B1 KR101773506B1 KR1020127005121A KR20127005121A KR101773506B1 KR 101773506 B1 KR101773506 B1 KR 101773506B1 KR 1020127005121 A KR1020127005121 A KR 1020127005121A KR 20127005121 A KR20127005121 A KR 20127005121A KR 101773506 B1 KR101773506 B1 KR 101773506B1
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- C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
- C07K16/3092—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated mucins
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- C07K2317/00—Immunoglobulins specific features
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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| EP09009942.5 | 2009-07-31 | ||
| PCT/EP2010/004663 WO2011012309A1 (en) | 2009-07-31 | 2010-07-30 | Muc1 antibodies |
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| KR20120051724A KR20120051724A (ko) | 2012-05-22 |
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| PT2073842E (pt) | 2006-09-10 | 2015-04-07 | Glycotope Gmbh | Utilização de células humanas provenientes de uma leucemia mielóide para expressão de anticorpos |
| EP1920782A1 (en) * | 2006-11-10 | 2008-05-14 | Glycotope Gmbh | Carboyhdrate specific cellular immunity inducing microorganisms and fractions thereof |
| EP2281844A1 (en) | 2009-07-31 | 2011-02-09 | Glycotope GmbH | MUC 1 antibodies |
| US8518405B2 (en) | 2009-10-08 | 2013-08-27 | The University Of North Carolina At Charlotte | Tumor specific antibodies and uses therefor |
| JP6334166B2 (ja) | 2010-08-10 | 2018-05-30 | グリコトープ ゲーエムベーハー | Ｆａｂグリコシル化抗体 |
| US9845362B2 (en) | 2010-10-08 | 2017-12-19 | The University Of North Carolina At Charlotte | Compositions comprising chimeric antigen receptors, T cells comprising the same, and methods of using the same |
| WO2013026887A1 (en) | 2011-08-22 | 2013-02-28 | Glycotope Gmbh | Microorganisms carrying a tumor antigen |
| CN103848890B (zh) * | 2012-11-30 | 2015-09-09 | 北京市结核病胸部肿瘤研究所 | Muc1自身抗体识别的抗原多肽 |
| EP2963126B1 (en) * | 2013-03-01 | 2019-04-03 | Saitama Medical University | Method for evaluating side-effect onset risk in anticancer drug treatment, including detecting muc4 gene polymorphism |
| US10208125B2 (en) * | 2013-07-15 | 2019-02-19 | University of Pittsburgh—of the Commonwealth System of Higher Education | Anti-mucin 1 binding agents and uses thereof |
| EP3127919A4 (en) * | 2014-02-06 | 2017-08-16 | Medicinal Chemistry Pharmaceuticals Co., Ltd. | Antibody against mucin 4 (muc 4) glycopeptide and use therefor |
| CA2947404C (en) * | 2014-04-28 | 2023-05-16 | Medicinal Chemistry Pharmaceuticals, Co., Ltd. | Anti-muc1 antibody or antigen-binding fragment thereof and uses thereof |
| WO2016026143A1 (en) * | 2014-08-22 | 2016-02-25 | Huiru Wang | Saccharide-based biomarkers and therapeutics |
| US11554181B2 (en) | 2014-09-05 | 2023-01-17 | The University Of North Carolina At Charlotte | Tumor specific antibody conjugates and uses therefor |
| WO2016130726A1 (en) * | 2015-02-10 | 2016-08-18 | Minerva Biotechnologies Corporation | Humanized anti-muc1* antibodies |
| WO2017139975A1 (en) | 2016-02-19 | 2017-08-24 | Huiru Wang | Antibodies against n-acetylglucosamine and n-acetyl-galactosamine |
| EP3543337B1 (en) | 2016-11-18 | 2022-04-20 | Astellas Pharma Inc. | Novel anti-human muc1 antibody fab fragment |
| EP3570881A4 (en) * | 2017-01-18 | 2020-08-19 | Nanocruise Pharmaceutical Ltd. | MONOCLONAL AND HUMANIZED ANTIBODIES DIRECTED AGAINST CANCER GLYCOPEPTIDE |
| EP3574015A1 (en) * | 2017-01-27 | 2019-12-04 | Glycotope GmbH | Anti-cancer treatments with an anti-muc1 antibody and an erbb inhibitor |
| JP2020511959A (ja) | 2017-03-29 | 2020-04-23 | グリコトープ ゲーエムベーハー | ヒト化抗ｃｄ４０抗体 |
| CA3057758A1 (en) * | 2017-03-29 | 2018-10-04 | Glycotope Gmbh | Pd-l1 and ta-muc1 antibodies |
| CA3055438A1 (en) * | 2017-03-29 | 2018-10-04 | Glycotope Gmbh | Multispecific antibody constructs binding to muc1 and cd3 |
| TWI795415B (zh) | 2017-07-07 | 2023-03-11 | 日商安斯泰來製藥股份有限公司 | 新穎的抗人類ＣＥＡＣＡＭ５抗體Ｆａｂ片段 |
| CN117003875A (zh) | 2017-09-29 | 2023-11-07 | 第一三共株式会社 | 抗体或其功能性片段、多核苷酸、表达载体、宿主细胞、糖链重构抗体、药物组合物、应用 |
| US11161911B2 (en) | 2017-10-23 | 2021-11-02 | Go Therapeutics, Inc. | Anti-glyco-MUC1 antibodies and their uses |
| EP3700936A4 (en) * | 2017-10-24 | 2021-05-26 | Go Therapeutics, Inc. | ANTI-GLYCO-MUC1 ANTIBODIES AND THEIR USES |
| CN111819203A (zh) * | 2018-03-01 | 2020-10-23 | 葛莱高托普有限公司 | 包含抗muc1抗体和il-15的融合蛋白构建体 |
| WO2019221269A1 (ja) * | 2018-05-17 | 2019-11-21 | アステラス製薬株式会社 | 抗ヒトＭＵＣ１抗体Ｆａｂフラグメント、ペプチドリンカー及び／又は配位子を含む複合体 |
| SG11202010496WA (en) | 2018-05-18 | 2020-12-30 | Daiichi Sankyo Co Ltd | Anti-muc1 antibody-drug conjugate |
| CN108982854B (zh) * | 2018-06-19 | 2021-07-27 | 哈尔滨医科大学 | 蛋白质muc13在制备诊断肝内胆管癌的试剂中的应用 |
| EP3814384A4 (en) * | 2018-06-29 | 2022-03-23 | Go Therapeutics, Inc. | ANTI-GLYC0-MUC1 ANTIBODIES AND THEIR USES |
| CN112839683B (zh) | 2018-10-10 | 2023-11-14 | 安斯泰来制药株式会社 | 含有标记部-抗人抗体Fab片段复合物的药物组合物 |
| TWI856078B (zh) | 2019-03-25 | 2024-09-21 | 日商第一三共股份有限公司 | 抗體–吡咯并苯二氮呯衍生物結合物、其製造方法及其用途 |
| CA3139180A1 (en) | 2019-03-27 | 2020-10-01 | Daiichi Sankyo Company, Limited | Combination of antibody-pyrrolobenzodiazepine derivative conjugate and parp inhibitor |
| CN118475617A (zh) * | 2021-12-21 | 2024-08-09 | 美勒斯公司 | 针对与癌症相关的muc1的结合域 |
| WO2023240135A2 (en) | 2022-06-07 | 2023-12-14 | Actinium Pharmaceuticals, Inc. | Bifunctional chelators and conjugates |
| TW202506190A (zh) | 2023-04-05 | 2025-02-16 | 日商第一三共股份有限公司 | 利用抗ｍｕｃ１抗體－藥物結合物投予的藥劑低敏感性癌之治療方法 |
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| US20060292643A1 (en) | 2003-01-23 | 2006-12-28 | Steffen Goletz | Recognition molecules for the treatment and detection of tumours |
| WO2008028686A2 (en) | 2006-09-10 | 2008-03-13 | Glycotope Gmbh | Use of human cells of myeloid leukaemia origin for expression of antibodies |
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| US5683674A (en) | 1987-01-07 | 1997-11-04 | Imperial Cancer Research Technology Ltd. | Antibody against human mucin core protein and method of preparing and using same |
| DE69329643T2 (de) | 1992-04-13 | 2001-03-01 | Dana-Farber Cancer Institute, Inc. | Gegen karzinom-assoziierte antigene gerichtete antikörper |
| US5804187A (en) | 1992-11-16 | 1998-09-08 | Cancer Research Fund Of Contra Costa | Modified antibodies with human milk fat globule specificity |
| US5739277A (en) | 1995-04-14 | 1998-04-14 | Genentech Inc. | Altered polypeptides with increased half-life |
| US6465220B1 (en) | 1998-12-21 | 2002-10-15 | Glycozym Aps | Glycosylation using GalNac-T4 transferase |
| US7147850B2 (en) | 1999-08-18 | 2006-12-12 | Altarex Medical Corp. | Therapeutic binding agents against MUC-1 antigen and methods for their use |
| ATE290879T1 (de) | 1999-08-18 | 2005-04-15 | Altarex Medical Corp | Therapeutische antikörper gegen das muc-1 antigen und verfahren zu deren verwendung |
| GB0029360D0 (en) | 2000-12-01 | 2001-01-17 | Univ Nottingham | Humanised antibodies and uses thereof |
| PT1529060E (pt) | 2002-07-22 | 2014-11-28 | Glycotope Gmbh | Processo para a produção de uma mucina imuno-estimuladora (muc1) |
| SI1530628T1 (sl) | 2002-08-16 | 2011-02-28 | Glycotope Gmbh | Postopek za proizvodnjo s temperaturo induciranih lizatov tumorskih celic za uporabo kot imunogenske spojine |
| PT1654353E (pt) | 2003-08-18 | 2013-08-23 | Glycotope Gmbh | Linhas de células tumorais nm f9 (dsm acc2606) e nm d4 (dsm acc2605), suas utilizações |
| JP4913604B2 (ja) | 2004-02-13 | 2012-04-11 | グリコトープ ゲーエムベーハー | 高活性糖タンパク質−製造条件、及びその効率的製造方法 |
| EP2281844A1 (en) | 2009-07-31 | 2011-02-09 | Glycotope GmbH | MUC 1 antibodies |
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| US20060292643A1 (en) | 2003-01-23 | 2006-12-28 | Steffen Goletz | Recognition molecules for the treatment and detection of tumours |
| WO2008028686A2 (en) | 2006-09-10 | 2008-03-13 | Glycotope Gmbh | Use of human cells of myeloid leukaemia origin for expression of antibodies |
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| AU2010278302B2 (en) | 2014-12-18 |
| JP5922018B2 (ja) | 2016-05-24 |
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| CU20120019A7 (es) | 2012-06-21 |
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