KR101746040B1 - 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제 - Google Patents

개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제 Download PDF

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KR101746040B1
KR101746040B1 KR1020157021992A KR20157021992A KR101746040B1 KR 101746040 B1 KR101746040 B1 KR 101746040B1 KR 1020157021992 A KR1020157021992 A KR 1020157021992A KR 20157021992 A KR20157021992 A KR 20157021992A KR 101746040 B1 KR101746040 B1 KR 101746040B1
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KR20150105471A (ko
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매튜 루드
나 트린
안드레아스 셔머
제이콥 가노
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알이지 라이프 사이언시스, 엘엘씨
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0108—Long-chain acyl-[acyl-carrier-protein] reductase (1.2.1.80)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fats And Perfumes (AREA)
KR1020157021992A 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제 Active KR101746040B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361753273P 2013-01-16 2013-01-16
US61/753,273 2013-01-16
PCT/US2014/011859 WO2014113571A2 (en) 2013-01-16 2014-01-16 Acyl-acp reductase with improved properties

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KR1020177015121A Division KR102082247B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제

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KR20150105471A KR20150105471A (ko) 2015-09-16
KR101746040B1 true KR101746040B1 (ko) 2017-06-13

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KR1020157021992A Active KR101746040B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제
KR1020177015121A Expired - Fee Related KR102082247B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제
KR1020207004969A Expired - Fee Related KR102265148B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제
KR1020217017654A Ceased KR20210072147A (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제

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KR1020207004969A Expired - Fee Related KR102265148B1 (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제
KR1020217017654A Ceased KR20210072147A (ko) 2013-01-16 2014-01-16 개선된 특성들을 갖는 아실-ａｃｐ 레덕타아제

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US (6) US9683219B2 (enExample)
EP (3) EP2946009B1 (enExample)
JP (5) JP6063585B2 (enExample)
KR (4) KR101746040B1 (enExample)
CN (3) CN110387352A (enExample)
AU (3) AU2014207522B2 (enExample)
BR (1) BR112015017005A2 (enExample)
CA (2) CA3143642A1 (enExample)
CO (1) CO7461134A2 (enExample)
ES (2) ES2675224T3 (enExample)
MX (2) MX356997B (enExample)
MY (1) MY167434A (enExample)
WO (1) WO2014113571A2 (enExample)

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US9447438B2 (en) 2013-03-15 2016-09-20 Cargill, Incorporated Acetyl-coA carboxylases
WO2015010103A2 (en) 2013-07-19 2015-01-22 Opx Biotechnologies, Inc. Microorganisms and methods for the production of fatty acids and fatty acid derived products
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
CN106574238B (zh) * 2014-07-18 2021-09-21 基因组股份公司 微生物的脂肪二醇产生
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
CN110494566A (zh) 2017-02-02 2019-11-22 嘉吉公司 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞
KR102677413B1 (ko) 2017-04-03 2024-06-24 게노마티카 인코포레이티드 중쇄 지방산 유도체의 생산을 위해 개선된 활성을 갖는 티오에스테라제 변이체
WO2020047088A1 (en) * 2018-08-31 2020-03-05 Genomatica, Inc. Production of non-native monounsaturated fatty acids in bacteria
EP3844179A4 (en) 2018-08-31 2022-08-31 Genomatica, Inc. XYLR MUTANT FOR IMPROVED XYLOSE UTILIZATION OR IMPROVED CO-UTILIZATION OF GLUCOSE AND XYLOSE
WO2023178193A1 (en) 2022-03-16 2023-09-21 Genomatica, Inc. Acyl-acp thioesterase variants and uses thereof

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Publication number Publication date
ES2675224T3 (es) 2018-07-09
MX346830B (es) 2017-04-03
ES2600354T3 (es) 2017-02-08
KR20200020998A (ko) 2020-02-26
KR20170066694A (ko) 2017-06-14
JP2017042170A (ja) 2017-03-02
CN110387352A (zh) 2019-10-29
CA2898317C (en) 2022-03-01
JP6523393B2 (ja) 2019-05-29
KR20210072147A (ko) 2021-06-16
AU2014207522B2 (en) 2016-12-15
EP3103867B1 (en) 2018-05-16
CA3143642A1 (en) 2014-07-24
MX356997B (es) 2018-06-22
WO2014113571A2 (en) 2014-07-24
US20200010813A1 (en) 2020-01-09
JP2017209118A (ja) 2017-11-30
US20160348080A1 (en) 2016-12-01
US20240117324A1 (en) 2024-04-11
CN105051189A (zh) 2015-11-11
KR20150105471A (ko) 2015-09-16
CN105051189B (zh) 2019-08-06
JP2016503663A (ja) 2016-02-08
US12173329B2 (en) 2024-12-24
US20150361454A1 (en) 2015-12-17
AU2017200596B2 (en) 2019-01-24
KR102082247B1 (ko) 2020-02-28
JP6063585B2 (ja) 2017-01-18
EP3385375B1 (en) 2021-06-16
US9873865B2 (en) 2018-01-23
AU2017200596A1 (en) 2017-02-23
EP3103867A1 (en) 2016-12-14
JP2019141083A (ja) 2019-08-29
EP2946009B1 (en) 2016-07-27
JP6926143B2 (ja) 2021-08-25
US9683219B2 (en) 2017-06-20
JP2021006067A (ja) 2021-01-21
MX2015009138A (es) 2015-11-06
AU2014207522A1 (en) 2015-05-07
JP6211162B2 (ja) 2017-10-11
MY167434A (en) 2018-08-28
EP2946009A2 (en) 2015-11-25
CN109897834A (zh) 2019-06-18
CO7461134A2 (es) 2015-11-30
AU2019202790A1 (en) 2019-05-16
US10208294B2 (en) 2019-02-19
WO2014113571A3 (en) 2014-11-13
CA2898317A1 (en) 2014-07-24
JP7094343B2 (ja) 2022-07-01
EP3385375A1 (en) 2018-10-10
US20220090028A1 (en) 2022-03-24
US20170342388A1 (en) 2017-11-30
US11130944B2 (en) 2021-09-28
BR112015017005A2 (pt) 2017-08-15
KR102265148B1 (ko) 2021-06-15

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