KR101709141B1 - ＴＮＦ-α 합성의 조절자 및 ＰＤＥ4 억제제로서 3고리 화합물 - Google Patents

ＴＮＦ-α 합성의 조절자 및 ＰＤＥ4 억제제로서 3고리 화합물 Download PDF

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KR101709141B1
KR101709141B1 KR1020107017176A KR20107017176A KR101709141B1 KR 101709141 B1 KR101709141 B1 KR 101709141B1 KR 1020107017176 A KR1020107017176 A KR 1020107017176A KR 20107017176 A KR20107017176 A KR 20107017176A KR 101709141 B1 KR101709141 B1 KR 101709141B1
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methoxy
quinoline
pyrimido
dione
phenyl
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KR20100103661A (ko
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아드난 엠 엠 므잘리
바푸 갓담
다르마 라오 폴리세티
매튜 코스투라
무스타파 규젤
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브이티브이 테라퓨틱스 엘엘씨
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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KR1020107017176A 2008-01-25 2009-01-23 ＴＮＦ-α 합성의 조절자 및 ＰＤＥ4 억제제로서 3고리 화합물 Active KR101709141B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2361708P 2008-01-25 2008-01-25
US61/023,617 2008-01-25
PCT/US2009/031819 WO2009094528A1 (en) 2008-01-25 2009-01-23 TRICYCLIC COMPOUNDS AS MODULATORS OF TNF-α SYNTHESIS AND AS PDE4 INHIBITORS

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KR20100103661A KR20100103661A (ko) 2010-09-27
KR101709141B1 true KR101709141B1 (ko) 2017-02-22

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US (10) US7964608B2 (enExample)
EP (1) EP2244574B1 (enExample)
JP (1) JP5406215B2 (enExample)
KR (1) KR101709141B1 (enExample)
CN (1) CN101925301B (enExample)
AU (1) AU2009206368B2 (enExample)
BR (1) BRPI0906809A2 (enExample)
CA (1) CA2711576C (enExample)
EA (1) EA018462B1 (enExample)
ES (1) ES2523169T3 (enExample)
IL (1) IL206854A (enExample)
MA (1) MA32035B1 (enExample)
MX (1) MX2010007768A (enExample)
NZ (1) NZ586695A (enExample)
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KR20200058599A (ko) * 2015-06-17 2020-05-27 화이자 인코포레이티드 삼환형 화합물 및 포스포다이에스터라제 억제제로서 이의 용도
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