KR101709141B1 - ＴＮＦ-α 합성의 조절자 및 ＰＤＥ4 억제제로서 3고리 화합물 - Google Patents
ＴＮＦ-α 합성의 조절자 및 ＰＤＥ4 억제제로서 3고리 화합물 Download PDFInfo
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- KR101709141B1 KR101709141B1 KR1020107017176A KR20107017176A KR101709141B1 KR 101709141 B1 KR101709141 B1 KR 101709141B1 KR 1020107017176 A KR1020107017176 A KR 1020107017176A KR 20107017176 A KR20107017176 A KR 20107017176A KR 101709141 B1 KR101709141 B1 KR 101709141B1
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- Prior art keywords
- methoxy
- quinoline
- pyrimido
- dione
- phenyl
- Prior art date
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| PCT/US2009/031819 WO2009094528A1 (en) | 2008-01-25 | 2009-01-23 | TRICYCLIC COMPOUNDS AS MODULATORS OF TNF-α SYNTHESIS AND AS PDE4 INHIBITORS |
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| KR20200058599A (ko) * | 2015-06-17 | 2020-05-27 | 화이자 인코포레이티드 | 삼환형 화합물 및 포스포다이에스터라제 억제제로서 이의 용도 |
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| HUE042374T2 (hu) | 2012-06-13 | 2019-06-28 | Incyte Holdings Corp | Szubsztituált triciklusos vegyületek mint FGFR inhibitorok |
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| US9266892B2 (en) | 2012-12-19 | 2016-02-23 | Incyte Holdings Corporation | Fused pyrazoles as FGFR inhibitors |
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| KR102469849B1 (ko) | 2013-04-19 | 2022-11-23 | 인사이트 홀딩스 코포레이션 | Fgfr 저해제로서 이환식 헤테로사이클 |
| US10851105B2 (en) | 2014-10-22 | 2020-12-01 | Incyte Corporation | Bicyclic heterocycles as FGFR4 inhibitors |
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| WO2017089347A1 (en) | 2015-11-25 | 2017-06-01 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and pharmaceutical compositions for the treatment of braf inhibitor resistant melanomas |
| MA47106A (fr) | 2016-12-21 | 2019-10-30 | Amgen Inc | Formulations d'anticorps anti-tnf alpha |
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| JP7720840B2 (ja) | 2019-12-04 | 2025-08-08 | インサイト・コーポレイション | Ｆｇｆｒ阻害剤としての三環式複素環 |
| KR20220131900A (ko) | 2019-12-04 | 2022-09-29 | 인사이트 코포레이션 | Fgfr 억제제의 유도체 |
| US12012409B2 (en) | 2020-01-15 | 2024-06-18 | Incyte Corporation | Bicyclic heterocycles as FGFR inhibitors |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20200058599A (ko) * | 2015-06-17 | 2020-05-27 | 화이자 인코포레이티드 | 삼환형 화합물 및 포스포다이에스터라제 억제제로서 이의 용도 |
| KR102426986B1 (ko) | 2015-06-17 | 2022-07-28 | 화이자 인코포레이티드 | 삼환형 화합물 및 포스포다이에스터라제 억제제로서 이의 용도 |
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