KR101628585B1 - 벤조티아졸론 화합물 - Google Patents

벤조티아졸론 화합물 Download PDF

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Publication number
KR101628585B1
KR101628585B1 KR1020147008777A KR20147008777A KR101628585B1 KR 101628585 B1 KR101628585 B1 KR 101628585B1 KR 1020147008777 A KR1020147008777 A KR 1020147008777A KR 20147008777 A KR20147008777 A KR 20147008777A KR 101628585 B1 KR101628585 B1 KR 101628585B1
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KR
South Korea
Prior art keywords
compound
hydroxybenzo
formula
butoxyphenyl
ylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1020147008777A
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English (en)
Korean (ko)
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KR20140057382A (ko
Inventor
준 카오
베른하르트 에르브
로빈 알렉 페어허스트
아르노 그항듀히
신지 하다키야마
막달레나 코지크자크-홀브로
신종 라이
필리프 루스텐베르거
베른트 리베젤
니콜라 투필리
토마스 울리치
시앙 우
지안구앙 주
Original Assignee
노파르티스 아게
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47010668&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR101628585(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
Publication of KR20140057382A publication Critical patent/KR20140057382A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/428Thiazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/08Acetic acid
    • C07C53/10Salts thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Cosmetics (AREA)
KR1020147008777A 2011-09-06 2012-09-05 벤조티아졸론 화합물 Expired - Fee Related KR101628585B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2011079379 2011-09-06
CNPCT/CN2011/079379 2011-09-06
PCT/IB2012/054580 WO2013035047A1 (en) 2011-09-06 2012-09-05 Benzothiazolone compound

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020167007782A Division KR101800140B1 (ko) 2011-09-06 2012-09-05 벤조티아졸론 화합물

Publications (2)

Publication Number Publication Date
KR20140057382A KR20140057382A (ko) 2014-05-12
KR101628585B1 true KR101628585B1 (ko) 2016-06-08

Family

ID=47010668

Family Applications (2)

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KR1020147008777A Expired - Fee Related KR101628585B1 (ko) 2011-09-06 2012-09-05 벤조티아졸론 화합물
KR1020167007782A Expired - Fee Related KR101800140B1 (ko) 2011-09-06 2012-09-05 벤조티아졸론 화합물

Family Applications After (1)

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US (6) US8933108B2 (enExample)
EP (1) EP2753609B1 (enExample)
JP (2) JP6130835B2 (enExample)
KR (2) KR101628585B1 (enExample)
CN (2) CN103781771B (enExample)
AP (1) AP3830A (enExample)
AR (1) AR087787A1 (enExample)
AU (1) AU2013200422C1 (enExample)
BR (1) BR112014004732A2 (enExample)
CA (1) CA2845766A1 (enExample)
CL (1) CL2014000493A1 (enExample)
CO (1) CO6900147A2 (enExample)
CR (1) CR20140114A (enExample)
CU (1) CU24303B1 (enExample)
CY (1) CY1118585T1 (enExample)
DK (1) DK2753609T3 (enExample)
EA (1) EA022909B1 (enExample)
ES (1) ES2615052T3 (enExample)
GT (1) GT201400042A (enExample)
HR (1) HRP20170075T1 (enExample)
HU (1) HUE030530T2 (enExample)
IL (1) IL231235A (enExample)
JO (1) JO3192B1 (enExample)
LT (1) LT2753609T (enExample)
MX (1) MX345405B (enExample)
MY (1) MY163301A (enExample)
PE (1) PE20141993A1 (enExample)
PH (1) PH12014500399A1 (enExample)
PL (1) PL2753609T3 (enExample)
PT (1) PT2753609T (enExample)
RS (1) RS55468B1 (enExample)
SG (1) SG2014013114A (enExample)
SI (1) SI2753609T1 (enExample)
TN (1) TN2014000060A1 (enExample)
TW (1) TWI555738B (enExample)
UA (1) UA114295C2 (enExample)
UY (1) UY34312A (enExample)
WO (1) WO2013035047A1 (enExample)
ZA (2) ZA201401112B (enExample)

Families Citing this family (6)

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JO3192B1 (ar) 2011-09-06 2018-03-08 Novartis Ag مركب بنزوثيازولون
UA117092C2 (uk) 2011-09-06 2018-06-25 Байєр Інтеллектуал Проперті Гмбх Амінозаміщені імідазопіридазини
EP3243817A1 (en) * 2012-08-30 2017-11-15 Novartis AG Salts of benzothiazolone compound as beta-2-adrenoceptor agonist
CN104797585B (zh) 2012-11-19 2017-08-15 拜耳医药股份公司 氨基咪唑并哒嗪
CN104968337A (zh) * 2013-02-28 2015-10-07 诺华股份有限公司 含有苯并噻唑酮化合物的制剂
US10967119B1 (en) 2019-04-01 2021-04-06 Azizi Bilal Wearable medication injecting device

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CN104968337A (zh) 2013-02-28 2015-10-07 诺华股份有限公司 含有苯并噻唑酮化合物的制剂

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PH12014500399A1 (en) 2021-06-02
AU2013200422B2 (en) 2014-08-07
CY1118585T1 (el) 2017-07-12
MY163301A (en) 2017-09-15
EA022909B1 (ru) 2016-03-31
US8933108B2 (en) 2015-01-13
CN106187942A (zh) 2016-12-07
HUE030530T2 (en) 2017-05-29
CR20140114A (es) 2014-05-06
LT2753609T (lt) 2017-01-10
CN103781771B (zh) 2016-08-24
GT201400042A (es) 2015-02-19
EP2753609A1 (en) 2014-07-16
KR20160038079A (ko) 2016-04-06
RS55468B1 (sr) 2017-04-28
US20150094346A1 (en) 2015-04-02
PT2753609T (pt) 2017-02-08
DK2753609T3 (en) 2017-02-06
WO2013035047A1 (en) 2013-03-14
BR112014004732A2 (pt) 2017-03-28
UY34312A (es) 2013-04-30
AU2013200422A1 (en) 2013-03-21
ES2615052T3 (es) 2017-06-05
SG2014013114A (en) 2014-07-30
ZA201401112B (en) 2016-01-27
AR087787A1 (es) 2014-04-16
MX2014002688A (es) 2014-04-14
US10251868B2 (en) 2019-04-09
CN106187942B (zh) 2020-06-26
CA2845766A1 (en) 2013-03-14
JP6340103B2 (ja) 2018-06-06
ZA201500790B (en) 2017-04-26
AP3830A (en) 2016-09-30
EP2753609B1 (en) 2016-11-09
CN103781771A (zh) 2014-05-07
IL231235A0 (en) 2014-04-30
US20180140582A1 (en) 2018-05-24
UA114295C2 (uk) 2017-05-25
TN2014000060A1 (en) 2015-07-01
PE20141993A1 (es) 2014-12-17
CU24303B1 (es) 2018-01-10
CU20140028A7 (es) 2014-05-27
US20160075670A1 (en) 2016-03-17
AP2014007462A0 (en) 2014-02-28
SI2753609T1 (sl) 2017-03-31
AU2013200422C1 (en) 2015-01-15
KR20140057382A (ko) 2014-05-12
CO6900147A2 (es) 2014-03-20
JO3192B1 (ar) 2018-03-08
US20150336914A1 (en) 2015-11-26
JP2017132781A (ja) 2017-08-03
JP6130835B2 (ja) 2017-05-17
TWI555738B (zh) 2016-11-01
CL2014000493A1 (es) 2014-10-03
US20160279107A1 (en) 2016-09-29
HRP20170075T1 (hr) 2017-03-24
EA201490573A1 (ru) 2014-06-30
TW201317221A (zh) 2013-05-01
US20130245080A1 (en) 2013-09-19
KR101800140B1 (ko) 2017-11-21
MX345405B (es) 2017-01-30
PL2753609T3 (pl) 2017-05-31
US9913828B2 (en) 2018-03-13
NZ621089A (en) 2015-07-31
JP2014525472A (ja) 2014-09-29
IL231235A (en) 2017-09-28

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