CU20140028A7 - Compuesto de benzotiazolona - Google Patents

Compuesto de benzotiazolona

Info

Publication number
CU20140028A7
CU20140028A7 CU2014000028A CU20140028A CU20140028A7 CU 20140028 A7 CU20140028 A7 CU 20140028A7 CU 2014000028 A CU2014000028 A CU 2014000028A CU 20140028 A CU20140028 A CU 20140028A CU 20140028 A7 CU20140028 A7 CU 20140028A7
Authority
CU
Cuba
Prior art keywords
benzotiazolona
composite
compound
present
provides
Prior art date
Application number
CU2014000028A
Other languages
English (en)
Other versions
CU24303B1 (es
Inventor
Jun Cao
Bernhard Erb
Robin Alec Fairhurst
Arnaud Grandeury
Shinji Hatakeyama
Magadalena Koziczak-Holbro
Xinzhong Lai
Philipp Lustenberger
Bernd Riebesehl
Nicola Tufilli
Thomas Ullrich
Xiang Wu
Jianguang Zhou
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47010668&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CU20140028(A7) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CU20140028A7 publication Critical patent/CU20140028A7/es
Publication of CU24303B1 publication Critical patent/CU24303B1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/08—Acetic acid
    • C07C53/10—Salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromonomer-Based Addition Polymer (AREA)

Abstract

La presente invención proporciona un compuesto de la fórmula( I) en forma libre o en forma de una sal farmacéuticamente aceptable, Un método para fabricar el compuesto de la invención, y sus usos terapéuticos. La presente invención proporciona además una combinación de agentes farmacológicamente activos y composiciones farmacéuticas.
CUP2014000028A 2011-09-06 2012-09-05 Compuesto de benzotiazolona CU24303B1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2011079379 2011-09-06
PCT/IB2012/054580 WO2013035047A1 (en) 2011-09-06 2012-09-05 Benzothiazolone compound

Publications (2)

Publication Number Publication Date
CU20140028A7 true CU20140028A7 (es) 2014-05-27
CU24303B1 CU24303B1 (es) 2018-01-10

Family

ID=47010668

Family Applications (1)

Application Number Title Priority Date Filing Date
CUP2014000028A CU24303B1 (es) 2011-09-06 2012-09-05 Compuesto de benzotiazolona

Country Status (39)

Country Link
US (6) US8933108B2 (es)
EP (1) EP2753609B1 (es)
JP (2) JP6130835B2 (es)
KR (2) KR101628585B1 (es)
CN (2) CN103781771B (es)
AP (1) AP3830A (es)
AR (1) AR087787A1 (es)
AU (1) AU2013200422C1 (es)
BR (1) BR112014004732A2 (es)
CA (1) CA2845766A1 (es)
CL (1) CL2014000493A1 (es)
CO (1) CO6900147A2 (es)
CR (1) CR20140114A (es)
CU (1) CU24303B1 (es)
CY (1) CY1118585T1 (es)
DK (1) DK2753609T3 (es)
EA (1) EA022909B1 (es)
ES (1) ES2615052T3 (es)
GT (1) GT201400042A (es)
HR (1) HRP20170075T1 (es)
HU (1) HUE030530T2 (es)
IL (1) IL231235A (es)
JO (1) JO3192B1 (es)
LT (1) LT2753609T (es)
MX (1) MX345405B (es)
MY (1) MY163301A (es)
PE (1) PE20141993A1 (es)
PH (1) PH12014500399A1 (es)
PL (1) PL2753609T3 (es)
PT (1) PT2753609T (es)
RS (1) RS55468B1 (es)
SG (1) SG2014013114A (es)
SI (1) SI2753609T1 (es)
TN (1) TN2014000060A1 (es)
TW (1) TWI555738B (es)
UA (1) UA114295C2 (es)
UY (1) UY34312A (es)
WO (1) WO2013035047A1 (es)
ZA (2) ZA201401112B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA117092C2 (uk) 2011-09-06 2018-06-25 Байєр Інтеллектуал Проперті Гмбх Амінозаміщені імідазопіридазини
JO3192B1 (ar) 2011-09-06 2018-03-08 Novartis Ag مركب بنزوثيازولون
EA029946B1 (ru) * 2012-08-30 2018-06-29 Новартис Аг СОЛИ СОЕДИНЕНИЯ БЕНЗОТИАЗОЛОНА В КАЧЕСТВЕ АГОНИСТОВ β-2-АДРЕНОРЕЦЕПТОРОВ
US9783543B2 (en) 2012-11-19 2017-10-10 Bayer Pharma Aktiengesellschaft Aminoimidazopyridazines
EP2961391B1 (en) * 2013-02-28 2017-05-17 Novartis AG Formulation comprising benzothiazolone compound
US10967119B1 (en) 2019-04-01 2021-04-06 Azizi Bilal Wearable medication injecting device

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JO3192B1 (ar) 2011-09-06 2018-03-08 Novartis Ag مركب بنزوثيازولون
EA029946B1 (ru) * 2012-08-30 2018-06-29 Новартис Аг СОЛИ СОЕДИНЕНИЯ БЕНЗОТИАЗОЛОНА В КАЧЕСТВЕ АГОНИСТОВ β-2-АДРЕНОРЕЦЕПТОРОВ
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Also Published As

Publication number Publication date
US20150336914A1 (en) 2015-11-26
AP3830A (en) 2016-09-30
CN106187942A (zh) 2016-12-07
AU2013200422C1 (en) 2015-01-15
CU24303B1 (es) 2018-01-10
MX345405B (es) 2017-01-30
PL2753609T3 (pl) 2017-05-31
TN2014000060A1 (en) 2015-07-01
RS55468B1 (sr) 2017-04-28
TW201317221A (zh) 2013-05-01
UA114295C2 (uk) 2017-05-25
NZ621089A (en) 2015-07-31
PT2753609T (pt) 2017-02-08
ZA201500790B (en) 2017-04-26
KR101628585B1 (ko) 2016-06-08
CL2014000493A1 (es) 2014-10-03
IL231235A (en) 2017-09-28
EP2753609A1 (en) 2014-07-16
GT201400042A (es) 2015-02-19
CN103781771B (zh) 2016-08-24
HRP20170075T1 (hr) 2017-03-24
US20150094346A1 (en) 2015-04-02
WO2013035047A1 (en) 2013-03-14
US20180140582A1 (en) 2018-05-24
JP6340103B2 (ja) 2018-06-06
JP2017132781A (ja) 2017-08-03
CY1118585T1 (el) 2017-07-12
JO3192B1 (ar) 2018-03-08
US20160279107A1 (en) 2016-09-29
US9913828B2 (en) 2018-03-13
CN103781771A (zh) 2014-05-07
KR20140057382A (ko) 2014-05-12
KR20160038079A (ko) 2016-04-06
US20130245080A1 (en) 2013-09-19
JP6130835B2 (ja) 2017-05-17
UY34312A (es) 2013-04-30
CO6900147A2 (es) 2014-03-20
PE20141993A1 (es) 2014-12-17
MY163301A (en) 2017-09-15
ZA201401112B (en) 2016-01-27
SG2014013114A (en) 2014-07-30
BR112014004732A2 (pt) 2017-03-28
EP2753609B1 (en) 2016-11-09
CA2845766A1 (en) 2013-03-14
US8933108B2 (en) 2015-01-13
PH12014500399A1 (en) 2021-06-02
EA022909B1 (ru) 2016-03-31
CN106187942B (zh) 2020-06-26
IL231235A0 (en) 2014-04-30
AR087787A1 (es) 2014-04-16
AU2013200422B2 (en) 2014-08-07
CR20140114A (es) 2014-05-06
AP2014007462A0 (en) 2014-02-28
AU2013200422A1 (en) 2013-03-21
EA201490573A1 (ru) 2014-06-30
MX2014002688A (es) 2014-04-14
SI2753609T1 (sl) 2017-03-31
JP2014525472A (ja) 2014-09-29
DK2753609T3 (en) 2017-02-06
ES2615052T3 (es) 2017-06-05
US10251868B2 (en) 2019-04-09
KR101800140B1 (ko) 2017-11-21
HUE030530T2 (en) 2017-05-29
US20160075670A1 (en) 2016-03-17
TWI555738B (zh) 2016-11-01
LT2753609T (lt) 2017-01-10

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