KR101558829B1 - 글루카곤 유사 펩타이드 1 （ｇｌｐ-1） 약제학적 제제 - Google Patents

글루카곤 유사 펩타이드 1 （ｇｌｐ-1） 약제학적 제제 Download PDF

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KR101558829B1
KR101558829B1 KR1020147011316A KR20147011316A KR101558829B1 KR 101558829 B1 KR101558829 B1 KR 101558829B1 KR 1020147011316 A KR1020147011316 A KR 1020147011316A KR 20147011316 A KR20147011316 A KR 20147011316A KR 101558829 B1 KR101558829 B1 KR 101558829B1
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South Korea
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glp
fdkp
diketopiperazine
particles
concentration
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KR1020147011316A
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English (en)
Korean (ko)
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KR20140072138A (ko
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스테파니 그리네
데이비드 브란트
코하바 겔베르
마크 킹
웨이맨 웬델 치트햄
케이트 오베르그
안드레아 레온-베이
마크 제이. 호킨슨
메리 패리스
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맨카인드 코포레이션
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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  • Gastroenterology & Hepatology (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
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KR1020147011316A 2006-04-14 2007-04-16 글루카곤 유사 펩타이드 1 （ｇｌｐ-1） 약제학적 제제 KR101558829B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74488206P 2006-04-14 2006-04-14
US60/744,882 2006-04-14
PCT/US2007/066728 WO2007121411A2 (en) 2006-04-14 2007-04-16 Glucagon-like peptide 1(glp-1) pharmaceutical formulations

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KR1020087027774A Division KR101438839B1 (ko) 2006-04-14 2007-04-16 글루카곤 유사 펩타이드 1 （ｇｌｐ-1） 약제학적 제제

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KR1020157008571A Division KR20150042304A (ko) 2006-04-14 2007-04-16 글루카곤 유사 펩타이드 1 （ｇｌｐ-1） 약제학적 제제

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KR20140072138A KR20140072138A (ko) 2014-06-12
KR101558829B1 true KR101558829B1 (ko) 2015-10-08

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KR1020157008571A KR20150042304A (ko) 2006-04-14 2007-04-16 글루카곤 유사 펩타이드 1 （ｇｌｐ-1） 약제학적 제제
KR1020147011316A KR101558829B1 (ko) 2006-04-14 2007-04-16 글루카곤 유사 펩타이드 1 （ｇｌｐ-1） 약제학적 제제
KR1020087027774A KR101438839B1 (ko) 2006-04-14 2007-04-16 글루카곤 유사 펩타이드 1 （ｇｌｐ-1） 약제학적 제제

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Country Link
EP (1) EP2010155A2 (ja)
JP (3) JP5415938B2 (ja)
KR (3) KR20150042304A (ja)
CN (2) CN101453988A (ja)
AU (1) AU2007238000B2 (ja)
BR (1) BRPI0709964A2 (ja)
CA (1) CA2646400A1 (ja)
HK (1) HK1206241A1 (ja)
MX (1) MX2008013216A (ja)
RU (3) RU2542500C2 (ja)
WO (1) WO2007121411A2 (ja)

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