KR101508397B1 - 염증성 장 질환의 검출 방법 - Google Patents

염증성 장 질환의 검출 방법 Download PDF

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KR101508397B1
KR101508397B1 KR1020097019627A KR20097019627A KR101508397B1 KR 101508397 B1 KR101508397 B1 KR 101508397B1 KR 1020097019627 A KR1020097019627 A KR 1020097019627A KR 20097019627 A KR20097019627 A KR 20097019627A KR 101508397 B1 KR101508397 B1 KR 101508397B1
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cells
antibody
polypeptide
tissue
expression
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KR20090117898A (ko
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라우리 디흘
케네스 플라나간
리안 모
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제넨테크, 인크.
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2561/00—Nucleic acid detection characterised by assay method
    • C12Q2561/113—Real time assay
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
KR1020097019627A 2007-02-22 2008-02-22 염증성 장 질환의 검출 방법 Expired - Fee Related KR101508397B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US89119607P 2007-02-22 2007-02-22
US60/891,196 2007-02-22
US98775207P 2007-11-13 2007-11-13
US60/987,752 2007-11-13
US2417008P 2008-01-28 2008-01-28
US61/024,170 2008-01-28
PCT/US2008/054805 WO2008103962A2 (en) 2007-02-22 2008-02-22 Methods for detecting inflammatory bowel disease

Publications (2)

Publication Number Publication Date
KR20090117898A KR20090117898A (ko) 2009-11-13
KR101508397B1 true KR101508397B1 (ko) 2015-04-08

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US (3) US7875431B2 (enExample)
EP (2) EP2436781B1 (enExample)
JP (1) JP5761915B2 (enExample)
KR (1) KR101508397B1 (enExample)
CN (1) CN101663407B (enExample)
AT (1) ATE541059T1 (enExample)
AU (1) AU2008218199B2 (enExample)
BR (1) BRPI0807635A2 (enExample)
CA (1) CA2676790A1 (enExample)
DK (2) DK2140021T3 (enExample)
ES (2) ES2379413T3 (enExample)
IL (1) IL200130A (enExample)
MX (1) MX2009008736A (enExample)
NZ (1) NZ578980A (enExample)
PL (1) PL2140021T3 (enExample)
RU (1) RU2502806C2 (enExample)
SI (1) SI2140021T1 (enExample)
WO (1) WO2008103962A2 (enExample)
ZA (1) ZA200905258B (enExample)

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NZ578980A (en) * 2007-02-22 2012-03-30 Genentech Inc Methods for detecting inflammatory bowel disease
CN102465173A (zh) * 2010-11-08 2012-05-23 中国农业科学院植物保护研究所 青枯菌2号小种的特异性pcr检测方法
WO2012103337A2 (en) * 2011-01-26 2012-08-02 The Brigham And Women's Hospital, Inc. Assays and methods to sequence microbes directly from immune complexes
BR112013024453A2 (pt) 2011-03-24 2016-09-06 Opko Pharmaceuticals Llc seleção de biomarcadores em fluido biológico complexo usando bibliotecas com base em contas ou em partículas e kits diagnósticos
JP2012231786A (ja) * 2011-04-18 2012-11-29 Kyushu Univ 標的遺伝子の発現変化による食品機能成分及び医薬品感受性評価方法
US10001492B2 (en) * 2011-05-05 2018-06-19 Diagnodus Limited Method for diagnosing inflammatory bowel disease
WO2015067913A1 (en) 2013-11-07 2015-05-14 Diagnodus Limited Biomarkers
EP3345627B1 (en) 2011-06-03 2021-01-06 Ophidion Inc. Compositions and methods for transport across the blood brain barrier
RU2556573C1 (ru) * 2014-06-25 2015-07-10 Государственное бюджетное образовательное учреждение дополнительного профессионального образования "Российская медицинская академия последипломного образования" Министерства здравоохранения Российской Федерации (ГБОУ ДПО РМАПО Минздрава России) Способ дифференциальной диагностики хронических воспалительных заболеваний кишечника у детей
US11434303B2 (en) * 2017-06-28 2022-09-06 Bluefin Biomedicine, Inc. Anti-LY6H antibodies and antibody drug conjugates
WO2020160337A1 (en) * 2019-01-30 2020-08-06 The Broad Institute, Inc. Systems for evolved adeno-associated viruses (aavs) for targeted delivery
RU2698709C1 (ru) * 2019-03-25 2019-08-29 Федеральное бюджетное учреждение науки "Московский научно-исследовательский институт эпидемиологии и микробиологии им. Г.Н. Габричевского" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека Способ дифференциальной диагностики воспалительных заболеваний кишечника у детей
CN111876483B (zh) * 2020-05-29 2022-12-20 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） Lypd1在肝细胞癌诊断、治疗、预后和预测复发中的应用
AU2022233979A1 (en) * 2021-03-12 2023-10-26 Janssen Biotech, Inc. Methods for predicting treatment response in ulcerative colitis
CN113429453B (zh) * 2021-08-05 2023-04-07 江西农业大学 Ctv三肽及其应用
WO2025122587A2 (en) * 2023-12-04 2025-06-12 Normunity, Inc. Anti-ly6k antibodies and methods of use

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