KR101444486B1 - 인돌 화합물 - Google Patents

인돌 화합물 Download PDF

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Publication number
KR101444486B1
KR101444486B1 KR1020097010151A KR20097010151A KR101444486B1 KR 101444486 B1 KR101444486 B1 KR 101444486B1 KR 1020097010151 A KR1020097010151 A KR 1020097010151A KR 20097010151 A KR20097010151 A KR 20097010151A KR 101444486 B1 KR101444486 B1 KR 101444486B1
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KR
South Korea
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group
substituted
alkyl
compound
optionally substituted
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Expired - Fee Related
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KR1020097010151A
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English (en)
Korean (ko)
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KR20090068292A (ko
Inventor
츠네오 야스마
오사무 우지카와
마사히로 이토
가즈코 아오키
Original Assignee
다케다 야쿠힌 고교 가부시키가이샤
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Publication of KR20090068292A publication Critical patent/KR20090068292A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
KR1020097010151A 2006-10-19 2007-10-18 인돌 화합물 Expired - Fee Related KR101444486B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2006285551 2006-10-19
JPJP-P-2006-285551 2006-10-19
PCT/JP2007/070772 WO2008050821A1 (en) 2006-10-19 2007-10-18 Indole compound

Publications (2)

Publication Number Publication Date
KR20090068292A KR20090068292A (ko) 2009-06-25
KR101444486B1 true KR101444486B1 (ko) 2014-09-24

Family

ID=39010108

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097010151A Expired - Fee Related KR101444486B1 (ko) 2006-10-19 2007-10-18 인돌 화합물

Country Status (26)

Country Link
US (4) US7652133B2 (https=)
EP (2) EP2508524A3 (https=)
JP (1) JP5260507B2 (https=)
KR (1) KR101444486B1 (https=)
CN (1) CN101573357B (https=)
AU (1) AU2007310064B2 (https=)
BR (1) BRPI0717722A2 (https=)
CA (1) CA2666973C (https=)
CL (1) CL2008001017A1 (https=)
CR (1) CR10748A (https=)
EC (1) ECSP099330A (https=)
GE (1) GEP20115241B (https=)
IL (1) IL198154A (https=)
MA (1) MA30890B1 (https=)
ME (1) ME00681B (https=)
MX (1) MX2009003972A (https=)
MY (1) MY158052A (https=)
NO (1) NO20091948L (https=)
NZ (1) NZ576570A (https=)
PE (1) PE20090884A1 (https=)
RU (1) RU2454415C9 (https=)
TN (1) TN2009000129A1 (https=)
TW (1) TWI460176B (https=)
UA (1) UA97257C2 (https=)
WO (1) WO2008050821A1 (https=)
ZA (1) ZA200902585B (https=)

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WO2005049019A1 (en) 2003-11-24 2005-06-02 Novo Nordisk A/S N-heteroaryl indole carboxamides and analogues thereof, for use as glucokinase activators in the treatment of diabetes

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