KR101391545B1 - Toothpaste containing medicinal herbs and propolis - Google Patents

Toothpaste containing medicinal herbs and propolis Download PDF

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KR101391545B1
KR101391545B1 KR1020130107835A KR20130107835A KR101391545B1 KR 101391545 B1 KR101391545 B1 KR 101391545B1 KR 1020130107835 A KR1020130107835 A KR 1020130107835A KR 20130107835 A KR20130107835 A KR 20130107835A KR 101391545 B1 KR101391545 B1 KR 101391545B1
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propolis
weight
toothpaste
herbal
extract
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KR1020130107835A
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Korean (ko)
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어수옥
심재경
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주식회사 경방
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Priority to PCT/KR2014/008247 priority patent/WO2015034252A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Zoology (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to a herbal toothpaste containing a herbal extract and propolis, which has functions of minimizing the stimulation of the toothpaste by adding, to the toothpaste, a herbal extract extracted from cnidium, Korean angelica root, Angelica dahurica root, mint, perennial artemisia, licorice, and pine needles to whiten teeth, clean plague, and inhibit periodontal diseases, improving the efficacy and feeling of a herbal medicine, and preventing and treating cavities and periodontitis as well as maintaining the teeth and oral cavity hygienically by improving sterilizing power for killing bacteria and preventing inflammation in the oral cavity. According to the present invention, toothpaste containing a herbal extract and propolis is provided. The herbal extract including cnidium, Korean angelica root, Angelica dahurica root, mugwort, licorice and pine needles, and the propolis are added to the toothpaste. The toothpaste comprises: precipitated calcium carbonate and calcium hydrogen phosphate which are abrasives for cleaning the outer surface of teeth; aminocaproic acid and allantoin chloro hydroxyl aluminum which are medicines for preventing periodontal diseases and inflammation; sorbitol, glycerin and, and xylitol which are wetting agents for preventing coagulation; polyethylene glycol (PEG), carboxymethyl cellulose (CMC), and xanthan gum which are binders for binding powder and a liquid component; sodium lauryl sulfate which is a foaming agent for making the quick dispersion and penetration of medicinal components; sodium benzoate, green tea extract, sodium saccharin, menthol, peppermint oil, and Food Blue No.1 which are additives for inhibiting the growth of microorganisms and improving feeling; and purified water.

Description

한방추출물과 프로폴리스가 첨가된 치약 {Toothpaste containing medicinal herbs and propolis}Toothpaste containing < RTI ID = 0.0 > medicinal < / RTI > herbs and propolis &

본 발명은 치아 미백과 프라그 제거 및 치주질환을 억제하기 위한 통상적인 치약에 천궁, 당귀, 백지, 박하, 사철쑥, 감초, 솔잎으로부터 추출한 한약재추출물과 프로폴리스를 첨가하여 치약의 자극을 최소화함은 물론이고, 사용감을 개선하며 구강내의 항균 및 염증 예방을 위한 살균력을 향상시켜 치아 및 구강을 청결하게 유지할 수 있을 뿐만 아니라, 충치 및 치주염을 예방하며 치료하는 기능을 가지는 한방추출물과 프로폴리스가 첨가된 치약에 관한 것이다.
The present invention minimizes irritation of toothpaste by adding herbal medicine extracts and propolis extracted from Astragalus membranaceae, Angelica gigas, Bacillus thuringiensis, Bacillus thuringiensis, Peppermint, Lycopersicon esculentum, Licorice and Pine needle to a tooth paste for suppression of tooth whitening, plaque removal and periodontal disease And it is possible to improve the feeling of use and to improve the sterilizing power for preventing the antibacterial and inflammation in the oral cavity and to maintain the teeth and oral cavity clean as well as to prevent the tooth decay and periodontal disease, .

치약이 존재하기 이전시대에는 식물의 줄기나 잎 등으로 치아를 문질러서 양치를 하였으나 프라그의 제거 및 세정효과가 미흡하였다.Before the toothpaste was present, teeth were rubbed and rubbed with the stem or leaf of the plant, but the removal and washing effect of the prage was insufficient.

따라서 이를 개선하기 위하여 분말가루형태의 치분(齒紛:가루로 된 치약)이 등장하게 되었다.Therefore, in order to improve this, a dental powder powder (powdered toothpaste) appeared.

그러나 상기 치분의 경우 세정효과를 위한 연마제가 주성분으로, 프라그 제거 및 세정교화는 증가하였지만 연마력이 지나치게 높아서 치약에 첨가하여 사용할 경우 치아를 마모시키는 등의 부작용이 발생되어 이를 개선하기 위한 현재의 반고형 치약이 등장하게 되었다.However, in the case of the above-mentioned dentifrice, the abrasive for the cleaning effect is the main component, and the removal of the plaque and the cleansing are increased. However, since the abrasive force is too high, when the tooth is added to the toothpaste, side effects such as abrasion of the tooth occur, Toothpaste appeared.

이와 같은 현재의 치약은 연마제와 함께 반고형의 형태를 유지하기 위하여 습윤제가 포함되어 있기 때문에 연마제의 함량을 조절하여 연마도를 원하는 수준으로 조정할 수 있다.Since the present toothpaste contains a wetting agent to maintain a semi-solid shape together with the abrasive, the polishing degree can be adjusted to a desired level by controlling the content of the polishing agent.

이 밖에 현대 치약은 프라그제거와 치아 세정이라는 기본기능이외에도 충치, 치은염, 구취, 미백 등과 같은 다양한 구강질환의 치료와 예방을 위하여 여러 가지 약효제 및 한약재를 사용함으로써 구강위생 개선에 기여하고 있다.In addition to the basic functions of removing plaque and tooth cleaning, modern toothpaste contributes to improvement of oral hygiene by using various medicines and herbal medicines for the treatment and prevention of various oral diseases such as tooth decay, gingivitis, bad breath and whitening.

특히 동서양을 막론하고 효능이 확인된 식물의 추출물을 정유 및 분말 형태로 치약에 적용하여 구강질환의 치료 및 예방에 사용하고 있다. 또한 벌꿀 추출물인 프로폴리스의 강력한 항균 작용을 통해 구강 질환을 억제할 수 있다.Especially, the extracts of plant, which have been proved to be efficacious both in the east and the west, are applied to dentifrices in the form of essential oils and powders and used for the treatment and prevention of oral diseases. It can also inhibit oral diseases through the powerful antibacterial action of propolis, a honey extract.

알려진 주요 기능성 치약에 관한 기술들은 다음과 같다. 공개번호 특1996-0003712호에는 프로폴리스를 함유한 치약조성물에 관한 것으로 프로폴리스를 0.01 내지 5.0중량%, 바람직하게는 0.1 내지 1.0% 포함하는 치약조성물이 기재되어 있고, 공개번호 특1997-0009782호에는 프로폴리스가 함유된 치약조성물에 관한 것으로 일반치약조성물에 프로폴리스의 알코올성 추출물 및 수용성 추출물을 5~15중량% 포함한 것이며, 공개번호 특1998-0008209호는 치약조성물에 관한 것으로 자몽종자 추출물 0.005 내지 1.0중량% 및 녹차추출물 0.01 내지 5.0중량%를 함유하는 치약조성물이 기재되어 있으며, 공개번호 특2000-0012139호는 프로폴리스 추출물에 관한 것으로, 내부표준으로서 p-에틸 페놀을 사용하는 가스 크로마토그래피에 의해 측정된, p-에틸 페놀에 대한 상대 체류시간이 0.7∼0.8인 냄새성분의 함유량 및/또는 상기와 마찬가지로 하여 측정된 상대 체류시간이 1.2∼1.3인 다른 냄새성분의 함유량이 감소된 프로폴리스 추출물에 관한 기술이며, 공개번호 2006-0108917호는 잇몸사랑 한방 치약에 관한 것으로 치주질환 예방과 치료효과를 나타내는 치약 조성물에 있어서 일반적인 치약 조성물인 아미노카프론산, 아파타이트 화학요법 제제 성분에 감초엑기스, 알란토인, 프로폴리스, 키토산, 자이리톨을 중량 기준으로 1:5 내지 1:6 비율로 함유하는 치주질환 예방과 치료용 치약조성물이 기재되어 있으며, 공개번호 2010-0117328호는 천연 스피어민트 분말이 함유된 치약 및 그 치약의 제조방법에 관한 것으로 통상의 치약 조성물에 천연 스피어민트 분말과 프로폴리스가 혼합된 혼합체를 중량비로 0.5-5% 함유시킨 천연 스피어민트 분말이 함유된 치약이 기재되어 있으며, 공개번호 2011-0137451호는 기능성 치약 조성물에 관한 것으로 치약 용량 100ml을 전체중량으로 할 때, 연마제 중 중조(탄산수소나트륨) 또는 천연 흡착 연마제로 천연 섬유질을 활용한 연마제로서 옷수수속대 분말 15g과, 죽염 30g과, 살균용 오디 식초 12g과, 카올린클레이 3g과, 글리세린 30g과, 송진가루 3g과, 오디 추축액 5g과, 알란토인 또는 프로폴리스 2g을 자몽씨 추출물 5방울과, 레몬 2방울 및 페파민트 4방울에 혼합하여 혼합공정중 수분의 발생을 통해 전체 중량을 맞추는 것을 특징으로 하는 기능성 치약 조성물이 기재되어 있으며, 공개번호 2012-0053370호는 연 추출물을 함유하는 시린이 예방 치약 조성물 및 그 제조방법에 관한 것으로 인산삼칼슘 5~15중량%, 글리세린 1~2중량%, D-솔비톨액 18.9~ 70.65중량%, 폴리에칠렌 글리콜 1~5중량%, 이산화규소 7.0~15.0중량%, 자일리톨 0.01~1.0중량%, 프로폴리스 0.01~0.6 중량%, 스테비오사이드 0.01~2.0중량%, 자몽종자추출물 0.01~2.0중량%, 홍화씨유 0.1~1.0 중량%, 연 추출물5~9.5중량%, 버드나무추출물 0.1~5.0중량%, 코카마이도프로필베타인 0.10~3.0중량%, DL-멘톨 0.01~2.0 중량% 및 정제수 10~ 18 중량%로 조성된 연 추출물을 이용한 시린이 예방 치약 조성물이 기재되어 있다.
Some of the known functional toothpaste technologies are as follows. Open Publication No. 1996-0003712 discloses a dentifrice composition containing propolis, which comprises 0.01 to 5.0% by weight, preferably 0.1 to 1.0% by weight of propolis, and has been disclosed in Korean Patent Publication No. 1997-0009782 Discloses a dentifrice composition containing propolis, wherein the general dentifrice composition contains 5 to 15 wt% of an alcoholic extract and a water-soluble extract of propolis, and the disclosure number 1998-0008209 relates to a dentifrice composition, 1.0% by weight and green tea extract in an amount of 0.01 to 5.0% by weight, and Publication No. 2000-0012139 discloses a propolis extract, which is obtained by gas chromatography using p-ethylphenol as an internal standard , The content of the odor component having a relative residence time to p-ethylphenol of 0.7 to 0.8 and / The present invention relates to a propolis extract having a reduced content of other odor components having a measured relative residence time of 1.2 to 1.3. The release number 2006-0108917 relates to a gum-loving herbal toothpaste, a dentifrice composition Dentifrice composition for prevention and treatment of periodontal disease, which contains aminocaproic acid as a general dentifrice composition, licorice extract, allantoin, propolis, chitosan and xylitol in a ratio of 1: 5 to 1: 6 on the basis of apatite chemotherapeutic preparation component Discloses a dentifrice containing natural spearmint powder and a method for producing the dentifrice. The dentifrice composition comprises a mixture of natural spearmint powder and propolis mixed in a conventional dentifrice composition at a weight ratio of 0.5-5% The toothpaste containing the natural spearmint powder contained therein is disclosed, and the disclosure number 2011-0137451 (Hydrogencarbonate) or a natural adsorbent abrasive as natural abrasives, 15 g of the powder of the water treatment agent, 30 g of bamboo salt, 30 g of sterilization aid, 12 g of vinegar, 3 g of kaolin clay, 30 g of glycerin, 3 g of rosin powder, 5 g of rhizome extract and 2 g of allantoin or propolis were mixed with 5 drops of grapefruit seed extract, 2 drops of lemon and 4 drops of peppermint, And the total weight is adjusted through the generation of water. The present invention relates to a preventive dentifrice composition containing a kite extract and a preparation method thereof, 1 to 2% by weight of glycerin, 18 to 70.65% by weight of D-sorbitol, 1 to 5% by weight of polyethylene glycol, 7.0 to 15.0% by weight of silicon dioxide, 0.01 to 1.0% by weight of xylitol, 0.01 to 0.6% by weight of a polis, 0.01 to 2.0% by weight of stevioside, 0.01 to 2.0% by weight of grapefruit seed extract, 0.1 to 1.0% by weight of safflower seed oil, 5 to 9.5% A preventive dentifrice composition is disclosed which comprises a soft extract prepared from 0.10-3.0% by weight of mydopropyl betaine, 0.01-2.0% by weight of DL-menthol and 10-18% by weight of purified water.

그러나 종래의 치약은 치주질환 및 각종 구강질환의 치료를 목적으로 동백나무과 식물의 잎에서 추출한 추출물을 함유하거나 각종 식물잎이나 꽃잎등의 추출물이 사용되고 있으나 이 경우, 각종 구강질환의 치료 및 예방의 효과는 있지만 치약을 장기간 사용 시 치약의 색상이 변질되거나 향이 변화되면서 치약에 함유된 약효제의 효과가 감소되고 사용 시 불쾌감을 유발하는 등 치약의 상품성이 떨어지는 문제점이 있었다.However, conventional toothpastes contain extracts extracted from leaves of Camellia crassifolia and various plant leaves or petals for the purpose of treatment of periodontal diseases and various oral diseases, but in this case, effects of treatment and prevention of various oral diseases There is a problem in that the color of the toothpaste is changed or the fragrance is changed when the toothpaste is used for a long period of time, the effect of the pharmacological effect agent contained in the toothpaste is reduced, and the commerciality of the toothpaste is deteriorated.

또한 프라그제거나 치은염의 치료효과를 높이기 위한 향미제로서 차나무로부터 추출 정제한 차나무 오일이 사용되고 있으나 이 경우 차나무 오일의 사용량이 적당한 향미를 구현하는 함량수준에서 그 사용량이 제한될 수 밖에 없으므로 치약에 첨가하여 사용하는 것이 용이하지 못한 문제점도 있었다.In addition, tea tree oil extracted and purified from tea tree is used as a flavor agent to increase the therapeutic effect of pragee gingivitis and gingivitis. However, in this case, since the use amount of tea tree oil is limited at the content level that satisfactory flavor is used, So that it is not easy to use it.

따라서 본 발명은 상기와 같은 종래의 치약의 문제점을 해소할 수 있도록 치약의 변형을 최대한 억제하고, 자극이 적으면서도 효능 및 사용감을 개선시킨 한방추출물과 프로폴리스가 첨감된 치약을 제공함에 그 목적이 있다.
Accordingly, it is an object of the present invention to provide a toothpaste with a herbal extract and a propolis-impregnated toothpaste, which is capable of minimizing the deformation of toothpaste and minimizing the irritation and improving the efficacy and feeling of use, so as to solve the problems of the conventional toothpaste. have.

본 발명은 상기와 같은 문제점을 해소하기 위하여 발명된 것으로, 치아 겉표면을 세정하기 위한 연마제인 침강탄산칼슘과 인산수소칼슘; 치주질환을 예방하고 염증을 방지하기 위한 약효제인 아미노카프론산과 알란토인클로로히드록시알루미늄; 응고를 막기 위한 습윤제인 솔비톨과 글리세린과 자일리톨; 분말과 액체성분을 결합하기 위한 결합제인 폴리에틸렌클리콜(PEG)과 카르복시메틸셀룰로오스(CMC)와 산탄검; 약효성분의 분산 및 침투를 신속하게 하기 위한 기포제인 라우릴황산나트륨; 미생물의 생육을 억제하고 사용감을 좋게하기 위한 첨가제인 안식향산나트륨과 녹차추출물과 삭카린나트륨과 멘톨과 페퍼민트유와 식용색소인 청색1호; 정제수로 제조된 치약에 천공, 당귀, 백지, 박하, 사철쑥, 감초, 솔잎을 포함하는 한방추출물과 프로폴리스가 첨가된 것을 특징으로 하는 한방추출물과 플로폴리스가 첨가된 치약을 제공한다.
Disclosure of Invention Technical Problem [8] The present invention has been made to solve the above-mentioned problems, and its object is to provide a method for cleaning tooth surface, Aminocaproic acid and allantoin chlorohydroxyaluminum, a pharmacological agent for preventing periodontal disease and preventing inflammation; Sorbitol, glycerin and xylitol as wetting agents to prevent clotting; Polyethylene glycol (PEG), carboxymethyl cellulose (CMC) and xanthan gum, which are binders for binding powder and liquid components; Sodium lauryl sulfate as a foaming agent for accelerating the dispersion and penetration of the active ingredient; Sodium benzoate, green tea extract, sodium saccharin, menthol, peppermint oil, and food coloring blue No. 1, which are additives to suppress the growth of microorganisms and improve the feeling of use; The present invention provides an oriental herbal extract and a toothpaste to which a flossol is added, wherein the toothpaste is prepared by adding purified water, herbal extract, Angelica japonica, Angelica keiskei, Bacillus subtilis,

이와 같이 본 발명은 통상적인 치약에 한약재인 천궁, 당귀, 백지, 박하, 쑥, 감초, 솔잎이 포함된 한방추출물과 벌꿀에서 추출한 프로폴리스를 첨가함으로써 각각의 한약재 성분의 향균 활성에 의하여 구강 염증을 예방 및 완화시키는 효과가 있으며 장기 보관 시에도 한약재의 안정성 및 치약의 색상과 향의 변화를 억제할 수 있을 뿐만 아니라 살균력을 높여 치아 및 구강을 청결하게 유지할 수 있고 사용감이 우수하여 남녀노소 누구든지 부담없이 사용할 수 있는 등 여러 가지의 효과가 있다.
As described above, the present invention can be applied to oral toothpaste by adding the oriental herb extracts including oriental herb, Angelica gigas, white spot, peppermint, mugwort, licorice, pine needle, and propolis extracted from honey to the oral toothpaste by the antibacterial activity of each herbal medicine ingredient. Prevention and alleviating effects. Also, it can prevent the stability of herbal medicines and changes in the color and flavor of toothpastes. Also, it can maintain the teeth and oral cavity clean by increasing the sterilizing power. It can be used without any effect.

본 발명은 치아 미백과 프라그 제거 및 치주질환을 억제하기 위한 치약에 관한 것으로, 치아 겉표면을 세정하기 위한 연마제인 침강탄산칼슘과 인산수소칼슘과 치주질환을 예방하고 염증을 방지하기 위한 약효제인 아미노카프론산과 알란토인클로로히드록시알루미늄과 응고를 막기 위한 습윤제인 솔비톨과 글리세린과 자일리톨과 분말과 액체성분을 결합하기 위한 결합제인 폴리에틸린글리콜(PEG)과 카르복시메틸셀룰로오스(CMC)와 산탄검과 약효성분의 분산 및 침투를 신속하게 하기 위한 기포제인 라우릴황산나트륨과 미생물의 생육을 억제하고 사용감을 좋게하기 위한 첨가제인 안식향산나트륨과 녹차추출물과 삭카린나트륨과 멘톨과 페퍼민트유와 식용색소인 청색1호와 정제수로 구성된다.The present invention relates to toothpaste for inhibiting tooth whitening, plaque removal, and periodontal disease, and a method of manufacturing toothpaste comprising the steps of: precipitating calcium carbonate and calcium hydrogen phosphate which are abrasives for cleaning tooth surface, Capronic acid and allantoin Chlorohydroxyaluminum and sorbitol, glycerin, and xylitol, which are wetting agents to prevent coagulation, polyethyleneglycol (PEG), carboxymethylcellulose (CMC) and xanthan gum Sodium lauryl sulfate, a foaming agent to accelerate the dispersion and penetration of ingredients, and sodium benzoate, green tea extract, saccharin sodium, menthol, peppermint oil, and blue No. 1, a food coloring agent, And purified water.

즉, 상기 연마제는 치아의 건표면을 세정하는 작용을 하는 성분으로써 침강탄산칼슘과 인산수소칼슘으로 구성되어 있다.That is, the abrasive is a component that cleans the surface of the tooth of the tooth, and is composed of precipitated calcium carbonate and calcium hydrogen phosphate.

그리고 약효제는 구강 내 세균을 살균하며 프라그의 생성을 억제하고 생성된 프라그를 제거하는 작용을 하는 성분으로 아미노카프론산과 알란토인클로로히드록시알루미늄으로 구성된다.The medicinal agent is composed of aminocaproic acid and allantoin chlorohydroxy aluminum as a component which sterilizes the bacteria in the oral cavity and inhibits the formation of plaque and removes the generated plaque.

또한, 습윤제는 치약의 반고형 형태를 만들기 위한 필수성분으로 치약이 공기중에 노출될 때 건조 및 고체화되는 것을 방지하며 치약의 표면에 윤기를 주는 작용을 하는 성분으로 솔비톨과 글리세린과 자일리톨로 구성되어 있다.In addition, the wetting agent is an essential ingredient for making a semi-solid form of toothpaste, which prevents the toothpaste from drying and solidifying when exposed to air, and is a component that acts as a glaze on the surface of the toothpaste and is composed of sorbitol, glycerin and xylitol .

그리고 고체인 분말 성분과 액체 성분이 분리되지 않게 해주는 역할을 하므로 반고형의 치약에서는 필수적으로 사용되는 결합제는 폴리에틸린글리콜(PEG)과 카르복시메틸셀룰로오스(CMC)와 산탄검으로 구성된다.And because it serves to prevent separation of solid powder component and liquid component, binder which is essential in semi-solid toothpaste is composed of polyethyleneglycol (PEG), carboxymethyl cellulose (CMC) and xanthan gum.

이 밖에 약효 성분의 분산 및 침투를 신속하게 하고 계면장력을 감소시킴으로서 구강내 이물질을 쉽게 떨어지게 하는 작용을 하는 기포제는 음이온성계면활성제인 라우릴황산나트륨으로 구성되며, 치약의 사용감을 좋게하기 위한 첨가제는 안식향산나트륨과 녹차추출물과 삭카린나트륨과 멘톨과 페퍼민트유로 구성되어 있다.In addition, the foaming agent, which facilitates the dispersion and penetration of the active ingredients and reduces the interfacial tension, makes the drop in the oral cavity easily composed of sodium lauryl sulfate, an anionic surfactant, and an additive for improving the feeling of use of the toothpaste It is composed of sodium benzoate and green tea extract, sodium saccharin, menthol and peppermint oil.

상기와 같은 구성성분에 정제수가 함유된 치약에 한약재인 천공, 당귀, 백지, 박하, 사철쑥, 감초, 솔잎을 포함하는 한방추출물과 프로폴리스가 첨가된 것이 본 발명의 특징이다. 상기와 같은 각각의 한약재가 가지고 있는 효능 및 성분은 다음과 같다.It is a feature of the present invention that the herbal extracts containing the perianth, perianth gum, angelica, white paprika, peppermint, white mugwort, licorice, pine needles and propolis are added to the toothpaste containing purified water. The efficacy and ingredients of each herbal medicine as described above are as follows.

첫 번째로 천궁은 미나리과에 속한 다년생초본인 천궁 및 일천궁의 뿌리줄기로서 활혈거어약류에서 대표적인 약으로서 기와 혈의 원활한 순환을 도우며 몸 안으로 침입한 풍의 기운을 없애는 동시에 지통의 효과가 있으며 세정기능 및 향균기능을 가지고 있다.Firstly, it is the root stem of perennial herbaceous perennial herbaceous perennial herbaceous perennial herbaceous plant. It is a typical medicine in phytohemoglobin pharmacology. It helps smooth circulation of tile blood, eliminates the energy of the intrusion into the body, It has antibacterial function.

따라서 치약에 첨가하여 사용할 경우 치아의 겉표면에 생성되는 프라그의 예방과 생성된 프라그의 제거에 효과적이며 치통을 완화하는 효과도 있다.Therefore, when it is added to toothpaste, it is effective for prevention of plaque generated on the outer surface of tooth and removal of generated plaque, and also has an effect of alleviating toothache.

두 번째로 당귀는 미나리과에 속하는 다년생초본 당귀의 뿌리로서 보혈제의 대표적인 생약으로 혈을 보하고 흐름을 좋게하므로 빈혈이나 어혈로 인한 형행 장애에서 오는 동통증에 활용되고 있으며, 치약에 첨가하여 사용할 경우 풍으로 인한 치아의 통증을 치려하거나 구취를 없애는데 탁월한 효과가 있다.Secondly, it is the root of perennial herbaceous angelica belonging to the perennial herb that belongs to the periwinkle. It is used as a representative herbal medicine of the herb medicine and it is used for the bronchial pain due to anemia or hemorrhoids, It is an effective way to relieve toothache and to eliminate bad breath.

세 번째로 백지는 미나리과에 속하는 다년생초본인 구릿대의 뿌리로서 진통제의 대표적인 생약으로 각종 통증을 완화하는데 유용하다.Third, white paper is the root of the perennial herbaceous gourd belonging to the butterfly, and it is useful for alleviating various pain with typical herbal medicine of painkiller.

네 번재로 박하는 꿀풀과에 속한 다년생초본인 박하의 지상부전초로서 향기가 매우 좋고 강하며, 치약에 첨가하여 사용할 경우 구내의 악취제거에 탁월한 효과가 있으며 살균 및 방부의 효과도 있다.The mint is very good and strong, and when added to toothpaste, it has an excellent effect in removing odors in the premises and also has a sterilizing and preservative effect.

다섯 번째로 쑥은 국화과에 속한 사철쑥의 전초를 건조한 것으로 인진이라고도 하며 습열을 제고하고 황달을 치료하는데 사용되며 치약에 첨가하여 사용할 경우 구강병 원인균에 대한 우수한 향균효과를 얻을 수 있다.Fifth, mugwort is dried outpox of the black mugwort belonging to Asteraceae. It is also known as astaxanthin. It is used to treat moist jaundice and to treat jaundice. When added to toothpaste, excellent antimicrobial effect on oral pathogenic bacteria can be obtained.

여섯 번째로 감초는 콩과에 속한 다년생초본인 감초의 뿌리로서 모든 중독의 해독제로 사용되고 있으며, 한방뿐만 아니라 신약, 민간약으로도 아주 유용하게 쓰이고 있다.Sixth, licorice root is a perennial herbaceous licorice root belonging to bean curd. It is used as an antidote for all addicts. It is also very useful as a new medicine or a medicinal medicine as well as herbal medicine.

이 밖에 치약에 첨가하여 사용할 경우 감초에 포함되어 있는 리코리시딘과 리코리소플라반이라는 두가지 향균물질이 충치와 잇몸질환을 일으키는 주된 구강 박테리아를 죽이는 역할을 하므로 충치 및 잇몸질환을 치료하고 나아가 구강감염을 예방하는데 효과적이다.In addition, when added to toothpaste, two antimicrobial substances, lycorisidine and licorizole flavone, which are included in licorice, kill the main oral bacteria causing tooth decay and gum disease, so they treat tooth decay and gum disease, .

마지막으로 솔잎은 소나무의 잎에서 추출된 성분으로서 산소와 미네랄이 풍부하며 치약에 첨가하여 사용할 경우 솔잎에 함유되어 있는 피톤치드 성분이 향균작용을 하고 테르펜 성분이 산화작용을 억제하여 잇몸이 시리고 아플 때 통증을 완화하는 효과가 있으며 충치 및 치주질환으로 인한 입냄새의 제거에도 효과적이다.Finally, the pine leaves are extracted from the leaves of pine trees, and are rich in oxygen and minerals. When they are added to toothpaste, the phytoncide ingredient contained in the pine needles acts as an antibacterial agent, while the terpene ingredient inhibits oxidation, And it is also effective in removing the bad breath due to tooth decay and periodontal disease.

또한 '자연의 페니실린'이라 불리기도 하는 천연 항생물질인 프로폴리스(propolis)는 인체에 침입한 세균을 물리치기 위해 백혈구가 있듯이, 나무들이 생장점을 보호하거나 상처 부위의 오염을 방지하고 미생물을 차단하기 위해 스스로 분비하는 물질이다.Propolis, a natural antibiotic, also known as 'natural penicillin', protects the growth spots of the trees, prevents contamination of the wound area and blocks microbes, just as white blood cells are present to defeat bacteria that enter the body. It is a substance that secretes itself.

프로폴리스는 항균제, 항바이러스제, 소독약제, 항진균제, 항생물질의 원료로 쓰이는데, 인체에 유해한 성분이 아니므로 부작용이나 내성이 전혀 없어서 인체 내부나 외부의 상처, 궤양 치료에 효과적이며, 장기 복용하면 감기도 예방되고 피부도 좋아진다. 수많은 연구와 치료를 통해 프로폴리스의 면역조직 강화효능이 입증되었다. 특히 프로폴리스에 함유된 항산화제의 일종인 플라보노이드(flavonoids)는 인체의 면역체계와 직접적으로 관련되는 주요 성분으로 알려져 있다.Propolis is used as a raw material for antibacterial, antiviral, antiseptic, antifungal and antibiotic substances. It is not harmful to the human body and therefore has no side effects or resistance, so it is effective for the wound and ulcer treatment inside and outside of the human body. It is also prevented and the skin gets better. Numerous studies and treatments have proven the immune system-strengthening effect of propolis. Flavonoids, a type of antioxidant contained in propolis, are known to be a major component directly related to the immune system of the human body.

천연항생제로 불리는 프로폴리스는 피부 항산화효과, 항염증, 미백 등의 다양한 기능을 가지고 있다.Propolis, called natural antibiotic, has various functions such as skin antioxidant effect, anti inflammation, whitening.

여기서, 상기 프로 폴리스는 프로폴리스의 구성성분 중 가장 중요한 물질이 후라보노이드(Flavonoid)라고 할 수 있다. 1970년도에 구 소련의 과학아카데미에서 빌라누에바(U.H.Villanueva)박사는 프로폴리스속에 18종의 후라보노이드 성분이 들어 있음을 밝혀냈고, 그밖에 항생성분인 갈란지나 피오세모리나(Galangina Pinocemorina)가 들어있다고 발표함으로써 벌집 속이 무균상태를 유지할 수 있는 것은 바로 이 후라보노이드 성분 때문이라는 사실을 밝힌 바 있다.Herein, propolis is the most important constituent of propolis, and may be referred to as Flavonoid. In 1970, Dr. UHVillanueva from the former Soviet Academy of Sciences discovered 18 kinds of flavonoids in propolis, and announced that Galangina Pinocemorina, an antibiotic, It has been shown that this flavonoid component is responsible for maintaining the sterility of the genus.

후라보노이드는 식물계에 폭 넓게 분포되어 있으며 그 대부분은 배당체(glycoside)로 존재하고 있으나 프로폴리스에서 발견되는 후라보노이드의 특징은 대부분 가수분해되어 비당분성(aglycon)의 형태로 존재하고 있다.Flavonoids are widely distributed in the plant kingdom and most of them exist as glycosides. However, most of the flavonoids found in propolis are hydrolyzed and exist in the form of aglycon.

이 비당분성의 후라보이드는 우리 인체에 흡수되었을 때 나타나는 특징은 특정효소의 반응을 억제하는 작용(항산화작용), 세포막을 강화하는 작용으로 피부를 건강하고 아름답게 하는 미용작용, 결합조직의 강화작용(세포재생), 항 알레르기 작용과 알레르기를 일으키는 비만세포 내의 화학물질의 유리를 억제하는 작용, 체내의 식세포나 항체의 생성을 강화하여 신체조직의 면역력을 조절하여 항류마치스, 항에이즈 기능을 증강 하는 등 전반적인 생체의 면역기능을 촉진하여 감염에 대한 저항력을 높여준다. This non-sugar Flavoid is absorbed into the human body by the action of inhibiting the reaction of specific enzymes (antioxidant effect), the action of strengthening the cell membrane and the beauty and beauty of the skin, Cell regeneration), the action of inhibiting the release of chemical substances in mast cells that cause antiallergic action and allergy, the production of phagocytic cells and antibodies in the body to strengthen the anti-rheumatic and anti-AIDS function by controlling the immunity of the body tissues It promotes overall immune function in the body and increases resistance to infection.

본 발명의 한방추출물과 플로폴리스가 첨가된 치약 중 한방추출물과 프로폴리스의 함량은 0.2중량% 내지 1.0중량%가 바람직하며 더욱 바람직하게는 0.2중량% 내지 0.4중량%를 포함하는 것이다. 한방추출물과 프로폴리스의 함량이 0.2중량%보다 낮은 경우 본 발명에 의한 치약의 효능이 미흡하며, 1.0중량%를 초과하는 경우는 치약의 효능에 비하여 비용이 과다하게 증가하는 외에도 맛이나 냄새에 반감을 느끼게 되어 바람직하지 않은 것으로 실험되었다. The content of the herbal extract and the propolis in the dentifrice added with the herbal extract of the present invention and the propolis is preferably 0.2 to 1.0% by weight, more preferably 0.2 to 0.4% by weight. If the content of the herbal extract and the propolis is lower than 0.2 wt%, the effect of the toothpaste according to the present invention is insufficient. If the content exceeds 1.0 wt%, the cost of the toothpaste increases excessively, And it was experimentally proved to be undesirable.

그리고 한방추출물 및 프로폴리스 100중량%에 대한 각각 구성성분의 바람직한 함유량은 천궁 15~25중량%, 당귀 15~25중량%, 백지 15~25중량%, 박하 5~15중량%, 사철쑥 5~15중량%, 감초 2.5~7.5중량%, 솔잎 2.5~7.5중량% 프로폴리스 5~15중량%로 구성된다.
The preferred contents of the constituents in 100 weight% of oriental herb extract and propolis are 15 to 25 weight%, 15 to 25 weight% of Angelica japonica, 15 to 25 weight% of white paper, 5 to 15 weight% of mint, 5 to 15 weight% 2.5 to 7.5% by weight of licorice, 2.5 to 7.5% by weight of pine needle, and 5 to 15% by weight of propolis.

여기서, 하기 실시예1은 일반적인 치약구성물과 본 발명에 따라 추가적으로 첨가되는 한약재들의 함량비를 중심으로 치약의 제조방법을 나타낸 것이다.
Hereinafter, Example 1 shows a method of manufacturing a dentifrice based on the content ratio of the general dentifrice composition and the herbal medicaments additionally added according to the present invention.

1. 용제가 혼합된 습윤제에 결합제를 미리 분산하여 준비하고, 기타 성분들(약효제, 첨가제, 한방추출물)을 분산 혼합한 다음, 연마제를 투입하여 약 30분간 교반하였다.1. A binder was preliminarily dispersed in a wetting agent mixed with a solvent, and other components (medicinal agent, additive, herbal extract) were dispersed and mixed, and then the mixture was stirred for about 30 minutes.

2. 이어서, 기포제를 투입한 후 진공 상태에서 20분간 교반시켜 최종 제품을 수득하였다.2. Subsequently, after the foaming agent was added, the resultant was stirred in a vacuum for 20 minutes to obtain a final product.

이때, 상기 습윤제는 솔비톨 30g, 글리세린 5g, 자일리톨 10g으로 구성되고 상기 결합제는 PEG 0.5g, CMC 1g, 산탄검 0.3g으로 구성된다.At this time, the wetting agent was composed of 30 g of sorbitol, 5 g of glycerin, and 10 g of xylitol, and the binder consisted of 0.5 g of PEG, 1 g of CMC and 0.3 g of xanthan gum.

또한 기타 성분중 약효제는 아미노카프론산 0.1g, 알란토인클로로히드록시알루미늄 0.08g, 안식향산나트륨 0.01g으로 구성되고, Among the other components, the active agent is composed of 0.1 g of aminocaproic acid, 0.08 g of allantoin chlorohydroxy aluminum, and 0.01 g of sodium benzoate,

첨가제는 녹차추출물 11g, 삭카린나트륨 1g, 멘톨 7g, 페퍼민트유 8g, 청색1호(식용색소) 1.07g으로 구성되며, The additives consist of 11 g of green tea extract, 1 g of sodium saccharin, 7 g of menthol, 8 g of peppermint oil and 1.07 g of blue No. 1 (edible pigment)

정제수는 10g으로 구성된다.The purified water is composed of 10 g.

그리고 연마제는 침강탄산칼슘 14.55g, 인산수소칼슘 0.08g으로 구성되며 기포제는 라우릴황산나트륨 0.01g으로 구성된다.The abrasive is composed of 14.55 g of precipitated calcium carbonate and 0.08 g of calcium hydrogen phosphate, and the foaming agent is composed of 0.01 g of sodium lauryl sulfate.

이 밖에 본 발명의 특징에 따라 한방추출물과 프로폴리스가 첨가되는데, 상기 한방추출물에 포함되는 한약재는 천궁 0.06g, 당귀 0.06g, 백지 0.06g, 박하 0.03g, 사철쑥 0.03g, 감초 0.015g, 솔잎 0.015g 및 프로폴리스 0.030g 으로 구성되며 , 한방추출물 및 프로폴리스 100중량%에 대한 각각 구성성분의 함유량은 천궁 20중량%, 당귀 20중량%, 백지 20중량%, 박하 10중량%, 사철쑥 10중량%, 감초 5중량%, 솔잎 5중량% 프로폴리스 10중량%로 구성된다.In addition, the herb extract and propolis are added according to the features of the present invention. The herbal medicine contained in the herbal extract includes 0.06 g of Angelica gigantei, 0.06 g of Angelica giganta, 0.06 g of white gum, 0.03 g of peppermint, 0.015 g of propolis and 0.030 g of propolis. The content of each component in 100% by weight of oriental herbal extract and propolis was 20% by weight, 20% by weight of Angelica gigas Nakai, 20% by weight of white paper, 10% by weight of mint, 10% %, Licorice 5% by weight, pine needle 5% by weight propolis 10% by weight.

위와 같은 여러 가지의 효능을 가진 각각의 한약재로 구성된 한방추출물과 프로폴리스를 치약에 첨가함으로써 각각의 한약재와 프로폴리스가 서로 상승작용을 하여 치약의 자극을 최소화함은 물론이고, 한약재의 효능 및 사용감을 개선하며, 구강내의 항균 및 염증 예방을 위한 살균력을 향상시켜 치아 및 구강을 청결하게 유지할 수 있을 뿐만 아니라, 충치 및 치주염을 예방하며 치료하는 등의 여러 가지 효과를 얻을 수 있다.By adding herbal extracts and propolis composed of herbal medicines having various effects as described above to the toothpaste, the herbal medicines and the propolis are synergized with each other to minimize irritation of the toothpaste. It is possible to improve the sterilizing power for antibacterial and inflammation prevention in the oral cavity and to maintain the teeth and oral cavity clean, and to prevent and treat cavities and periodontitis.

이상에서 설명한 본 발명은 상술한 실시 예 및 첨부한 도면에 의해 한정되지 않으며, 본 발명의 기술적 사상을 벗어나지 않는 범위 내에서 치환, 변형 및 변환이 가능하다는 것을 본 발명이 속하는 기술 분야에서, 통상의 지식을 가진 자에게 있어서는 명백할 것이다.While the present invention has been described in connection with what is presently considered to be practical exemplary embodiments, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, It will be clear to those who have knowledge.

Claims (3)

치아 겉표면을 세정하기 위한 연마제인 침강탄산칼슘과 인산수소칼슘; 치주질환을 예방하고 염증을 방지하기 위한 약효제인 아미노카프론산과 알란토인클로로히드록시알루미늄; 응고를 막기 위한 습윤제인 솔비톨과 글리세린과 자일리톨; 분말과 액체성분을 결합하기 위한 결합제인 폴리에틸린글리콜(PEG)과 카르복시메틸셀룰로오스(CMC)와 산탄검; 약효성분의 분산 및 침투를 신속하게 하기 위한 기포제인 라우릴황산나트륨; 미생물의 생육을 억제하고 사용감을 좋게하기 위한 첨가제인 안식향산나트륨과 녹차추출물과 삭카린나트륨과 멘톨과 페퍼민트와 청색 1호; 정제수로 구성된 치약에 첨가되는 한방추출물 및 프로폴리스 100중량%에 대하여, 천궁 15~25중량%, 당귀 15~25중량%, 백지 15~25중량%, 박하 5~15중량%, 쑥 5~15중량%, 감초 2.5~7.5중량%, 솔잎 2.5~7.5중량%, 프로폴리스 5~15중량%가 첨가된 치약.
Precipitated calcium carbonate and calcium hydrogen phosphate as abrasives for cleaning tooth surface; Aminocaproic acid and allantoin chlorohydroxyaluminum, a pharmacological agent for preventing periodontal disease and preventing inflammation; Sorbitol, glycerin and xylitol as wetting agents to prevent clotting; Polyethyleneglycol (PEG), carboxymethylcellulose (CMC) and xanthan gum, which are binders for binding powder and liquid components; Sodium lauryl sulfate as a foaming agent for accelerating the dispersion and penetration of the active ingredient; Sodium benzoate, green tea extract, sodium saccharin, menthol, peppermint and blue No. 1, which are additives to suppress the growth of microorganisms and improve the feeling of use; 15 to 25% by weight of Angelica giganta, 15 to 25% by weight of Angelica giganta, 15 to 25% by weight of white paper, 5 to 15% by weight of mint, 5 to 15% by weight of mugwort, 2.5 to 7.5% by weight of licorice, 2.5 to 7.5% by weight of pine needle, and 5 to 15% by weight of propolis.
제 1항에 있어서,
한방추출물과 프로폴리스가 첨가된 치약 100중량%중 한방추출물과 프로폴리스의 함량이 0.2중량% 내지 1.0중량%인 것을 특징으로 하는 한방추출물과 프로폴리스가 첨가된 치약.
The method according to claim 1,
A herbal extract and a propolis-added toothpaste, characterized in that the herbal extract and the propolis content of the herbal extract and the propolis-added toothpaste are 0.2 wt% to 1.0 wt%.
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KR102458209B1 (en) 2022-04-19 2022-10-24 강삼용 Toothpaste containing crude drugs ingredients and method for producing the same
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KR102602562B1 (en) * 2023-02-15 2023-11-17 주식회사 아해바 Toothpaste

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