KR20070065955A - Toothpaste containing functional ingredients in microcapsules - Google Patents
Toothpaste containing functional ingredients in microcapsules Download PDFInfo
- Publication number
- KR20070065955A KR20070065955A KR1020050115214A KR20050115214A KR20070065955A KR 20070065955 A KR20070065955 A KR 20070065955A KR 1020050115214 A KR1020050115214 A KR 1020050115214A KR 20050115214 A KR20050115214 A KR 20050115214A KR 20070065955 A KR20070065955 A KR 20070065955A
- Authority
- KR
- South Korea
- Prior art keywords
- olive oil
- toothpaste
- microcapsules
- composition
- oliuropine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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Images
Classifications
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- A—HUMAN NECESSITIES
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/92—Oral administration
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
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- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
본 발명은 마이크로캡슐 내에 기능성 원료를 함유한 치약에 관한 것으로 연마제, 발포제, 습윤제, 점결제, 감미제, 향미제 및 보존제 등으로 이루어지는 겔 치약의 기본 조성물에 있어서, 상기 조성물에 올리브유 또는 올리유러핀을 내포한 마이크로캡슐이 함께 함유되어 이루어지며, 칫솔질 때 녹으면서 파괴되어 올리브유 또는 올리유러핀이 구강에 접촉되는 것을 특징으로 한다.The present invention relates to a toothpaste containing a functional raw material in a microcapsule. In the basic composition of a gel toothpaste comprising an abrasive, a foaming agent, a humectant, a caking additive, a sweetening agent, a flavoring agent and a preservative, the composition includes olive oil or oliuropine. The encapsulated microcapsules are contained together, and are broken down while being melted when brushed, so that the olive oil or oliuropin is in contact with the oral cavity.
본 발명은 치약 조성물에 함유된 마이크로캡슐(천연 올리브유 또는 올리유러핀을 내포한 젤라틴)이 녹으면서 파괴를 통해 방출되는 천연 올리브유 또는 올리유러핀의 항생성분이 구강에 접촉함으로써 바이러스 세균, 곰팡이균 및 기생균을 억제하며 또 살균 효능을 통해 각종 피부염과 궤양을 치료하고 피부를 좋게 만들어주는 효과를 얻게 된다. 또한, 올리브유 또는 올리유러핀은 인체에 전혀 해가 없으면서도 몸속의 유해한 콜레스테롤의 생성을 억제하는 불포화지방산의 함량이 식물성 기름 가운데 가장 높고 노화방지 및 성인병예방, 소화와 배변의 효과가 있음으로써 기존의 치약 조성물의 성분에 비해 더욱 강력한 구강 청결을 유지할 수 있다.The present invention provides a microbial capsule (natural olive oil or gelatin containing oliuropine) dissolved in the toothpaste composition, and the antibiotics of natural olive oil or oliuropin released through destruction contact with the oral cavity. It inhibits parasites and sterilizes the effects of treating various dermatitis and ulcers and improving skin. In addition, olive oil or oliuropine has the highest content of unsaturated fatty acids that inhibit the production of harmful cholesterol in the body without any harm to the human body, and has the effects of anti-aging and prevention of adult diseases, digestion and defecation. Stronger oral cleanliness can be maintained compared to the components of the toothpaste composition.
Description
도 1은 본 발명에 따른 마이크로캡슐이 함유된 불투명 치약을 나타낸 사진.1 is a photograph showing an opaque toothpaste containing microcapsules according to the present invention.
도 2는 본 발명에 따른 마이크로캡슐이 함유된 반투명 치약을 나타낸 사진이다.Figure 2 is a photograph showing a semi-transparent toothpaste containing a microcapsules according to the present invention.
본 발명은 치주·잇몸질환의 예방 및 치료에 효과가 우수한 치약에 관한 것으로 좀더 구체적으로는 마이크로캡슐(젤라틴) 안에 천연 올리브유 또는 올리유러핀을 함유함으로써 칫솔질할 때 마이크로캡슐의 파괴에 의해 올리브유 또는 올리유러핀이 치아와 직접 접촉되어 잇몸의 피부염과 궤양을 치료할 수 있도록 한 마이크로캡슐 내에 기능성 원료를 함유한 치약에 관한 것이다.The present invention relates to a toothpaste having an excellent effect on the prevention and treatment of periodontal and gum disease. More specifically, the microcapsule (gelatin) contains natural olive oil or oleuropine, and when brushed with olive oil or oli by destroying the microcapsules The present invention relates to a toothpaste containing a functional ingredient in a microcapsule in which europins are in direct contact with teeth to treat dermatitis and ulcers of the gums.
일반적으로 치약은 치아를 청결하게 하고 치석을 제거할 목적으로 칫솔에 묻혀 사용하는 약물성 복합물질로서 분말, 크림, 액상 등으로 만들어진다.In general, toothpaste is a drug compound used in a toothbrush for the purpose of cleaning teeth and removing tartar and is made of powder, cream, liquid, and the like.
상기 치약은 소독작용, 치석 용해작용, 냄새 감퇴작용 및 충치나 치조농루 등의 예방 또는 치료에 도움이 되도록 만들게 되고, 주성분의 기제(基劑)로서 탄산 칼슘, 인산칼슘, 황산칼슘, 탄산마그네슘 및 염화마그네슘 등이 사용된다. 상기 기제는 치아의 기계적 청소에 도움이 되는 것인데, 치아 표면의 손상을 방지하기 위하여 그 입자의 크기, 경도, 모양을 적절하게 조정하게 되며, 그 입자의 크기는 대략 1∼20μm으로서 균일한 형태를 이루면서 굳기는 모스 굳기 3도 정도로 요구된다.The toothpaste is made to help disinfection, calculus dissolution, odor decay and to prevent or treat tooth decay or alveolar rash, and as the base of the main ingredient, calcium carbonate, calcium phosphate, calcium sulfate, magnesium carbonate and Magnesium chloride and the like are used. The base is helpful for the mechanical cleaning of the teeth, and in order to prevent damage to the surface of the teeth, the size, hardness, and shape of the particles are appropriately adjusted. Hardening is required at about 3 degrees moss hardening.
근래에는 상기와 같은 종래의 치약 기제에 청정제, 향료, 색소, 살균소독제, 치석용해제, 중화제 등의 기능성 소재를 조금씩 혼입하여 충치예방, 잇몸질환예방 및 치태제거 효과를 얻는 다양한 기능성 제품을 출시하고 있다. 이들은 기초제에 미량 혼합된 상태로 제조되므로 사용할 때 기능성을 요구하는 소재의 효과를 제대로 얻기 어렵고 일부는 기초제의 안정성을 변화시킬 수 있으므로 적정량을 첨가할 수 없었다.Recently, various functional products such as detergents, flavorings, pigments, disinfectants, tartar dissolving agents, neutralizers, etc. are mixed little by little with the conventional toothpaste bases, and various functional products are obtained to prevent tooth decay, prevent gum disease, and remove plaque. . Since they are prepared in a very small amount mixed with the base agent, it is difficult to properly obtain the effect of the material that requires functionality when used, and some of them may change the stability of the base agent, and thus an appropriate amount cannot be added.
본 발명은 상술한 문제점을 해결하기 위한 것으로서, 본 발명의 목적은 치주·잇몸질환의 예방 및 치료에 효과가 우수한 기능성 원료를 담은 마이크로캡슐을 치약 조성물에 첨가함으로써 혼합되지 않고 성분이 안정적으로 유지되면서 칫솔질 때 마이크로캡슐이 녹으면서 파괴와 함께 방출된 올리브유 또는 올리유러핀이 직접 구강에 접촉되어 치료 및 윗몸 보호가 효과적으로 향상될 수 있도록 한 마이크로캡슐 내에 기능성 원료를 함유한 치약을 제공하는 데 있다.The present invention is to solve the above problems, an object of the present invention is to maintain the components stably without mixing by adding a microcapsule containing a functional raw material excellent in the prevention and treatment of periodontal and gum disease to the toothpaste composition The present invention provides a toothpaste containing a functional ingredient in a microcapsule so that olive oil or oliuropin released with destruction as the microcapsules are melted when brushed is directly contacted to the oral cavity so that treatment and upper body protection can be effectively improved.
또한, 본 발명은 기능성 원료인 올리브유 또는 올리유러핀을 담은 마이크로캡슐이 가시적으로 표출되도록 함으로써 미적 효과를 제공함은 물론 마이크로캡슐 의 파괴를 통하여 희석됨을 확인하면서 양치시간을 인지할 수 있도록 한 마이크로캡슐에 기능성 원료를 함유한 치약을 제공하는 데 있다. In addition, the present invention provides aesthetic effects by visually expressing the microcapsules containing the olive oil or oliuropin as a functional raw material in the microcapsules that can recognize the brushing time while confirming the dilution through the destruction of the microcapsules To provide a toothpaste containing a functional raw material.
상기 목적을 달성하기 위하여 본 발명은 연마제, 발포제, 습윤제, 점결제, 감미제, 향미제, 보존제 및 기타 약효성분으로 이루어지는 기본 조성물에 올리브유 또는 올리유러핀을 내포한 마이크로캡슐을 내포시키되 구분되어 식별되도록 한 것을 특징으로 하는 마이크로캡슐 내에 기능성 원료를 함유한 치약을 제공한다.In order to achieve the above object, the present invention includes a microcapsule containing olive oil or oliuropine in a basic composition consisting of an abrasive, a foaming agent, a wetting agent, a binder, a sweetener, a flavoring agent, a preservative, and other active ingredients, so as to be distinguished and identified. It provides a toothpaste containing a functional raw material in a microcapsule characterized in that one.
본 발명의 치약은 기본 조성물에 치주·잇몸질환의 예방 및 치료에 효과가 우수한 기능성을 지니는 올리브유 또는 올리유러핀을 내포한 젤라틴 성분의 마이크로캡슐을 0.05~1 중량%, 바람직하게는 0.2~0.5 중량%의 양을 포함한다.Toothpaste of the present invention is 0.05 to 1% by weight, preferably 0.2 to 0.5% by weight of the microcapsules of the gelatin component containing olive oil or oliuropine having excellent functionality in the prevention and treatment of periodontal and gum disease in the basic composition Contains the amount of%.
상기 마이크로캡슐은 1~5㎛ 범위의 크기로 단백질인 젤라틴으로 형성되며, 상기 올리브유 또는 올리유러핀 물질을 둘러싼 분체(粉體) 모양으로서 칫솔질 전에는 그 방출을 제어하고 사용시 녹으면서 파괴되어 올리브유 또는 올리유러핀을 방출하는 것이 주된 목적이다. The microcapsules are formed of gelatin, which is a protein with a size in the range of 1 to 5 μm. The microcapsules are shaped like powders surrounding the olive oil or oleuropine material. The main purpose is to release the europins.
상기 올리브유는 압착법(壓搾法), 추출법(抽出法)으로 채유하며, 올리브유는 구약성서에도 기록이 있을 만큼 오래전부터 이용되었던 식용유 또는 화장이나 치료용으로서 용도가 다양하다. 그 주성분은 지방산으로서 불포화산인 올레산(oleic acid)이며, 포화지방산으로는 팔미트산이 주성분이다. 그 색상은 담황색이며 냄새가 없고 담백한 맛이 난다. 공업용으로는 비누, 섬유윤활용, 머릿기름, 포마드용, 의약용으로는 도찰제(塗擦劑), 관장제, 연고, 주사용 용제로 널리 이용된다. 식용 유로는 샐러드유나 기름절임용에 주로 쓰이고, 요리에는 마요네즈, 샐러드용 드레싱, 튀김용, 볶음용으로 널리 이용된다. 식용유 중에서 최고급품으로 세계적으로 귀중하게 사용되는데, 특히 그리스, 에스파냐, 이탈리아에서 요리에 가장 널리 사용되고 있다. 특히 피부염과 궤양을 치료하고 피부를 좋게 만드는 항생제 효과를 지닌 것으로 확인되고 있다.The olive oil is oiled by a compression method (법 法), extraction (抽出 法), olive oil has a variety of uses as a cooking oil or cosmetics or therapeutics that have been used for a long time, even in the Old Testament. The main component is oleic acid which is an unsaturated acid as a fatty acid, and palmitic acid is a main component as saturated fatty acid. Its color is pale yellow and has no smell and tastes light. It is widely used as a coating agent, enema, ointment, and injection solvent for industrial purposes such as soap, fiber lubrication, hair oil, pomade, and medicine. Edible euro is mainly used for salad oil or pickled oil, and is widely used for cooking mayonnaise, salad dressing, frying and roasting. It is one of the highest quality oils in the world. It is most widely used in cooking in Greece, Spain and Italy. In particular, it has been shown to have an antibiotic effect that treats dermatitis and ulcers and improves skin.
상기 올리유러핀은 오직 올리브잎에서만 존재하는 특수 펜놀린 성분으로서 1970년 미국의 Upjhon co(업존사) 연구실에서 인류 최초로 올리브 잎에서 나오는 페놀린 성분을 분리하는데 성공을 하였고, 이를 명하여 올리유러핀이라 명칭 하였다. 이는 다시 10개의 세분 성분으로 나누어지며 그중에 엘렌올릭산( Elenolic acid ) 이라는 성분이 강력한 항생물로서 바이러스 세균, 곰팡이균 및 기생균을 억제하며, 또 살균함으로 세계에서 가장 안전하고 부작용이 없는 항생물질로 인정받게 되었다. 올리유러핀은 이러한 균들에 의하여 발생하는 각종 암과 백혈병 간염B,C형 독감, 감기 헤르페스 에이스 등을 억제하며 감염 상태를 완화함을 수많은 동물 시험과 실전 사용에서 입증이 되었다. 또한, 엘렌올릭산 다른 9가지 성분과 연합하여 당뇨 고혈압 심장질환 등에 좋은 반응을 보여 주며 인체의 면역성을 증강시켜 발병과 합병증 예방에 좋은 것으로 입증되고 있다.The oleuropein is a special phenolinol component that exists only in olive leaves and succeeded in separating the phenolic component from the olive leaf in humans in the Upjhon co (Upzone Co.) laboratory in the United States in 1970. It was named. It is divided into 10 subdivided components, among which Elenolic acid is a powerful antibiotic that inhibits viral bacteria, fungi and parasites, and sterilizes it to be the safest and most free antibiotic in the world. I got it. Oligoeurin has been demonstrated in numerous animal studies and practical use to suppress various cancers caused by these bacteria, leukemia hepatitis B, C influenza, cold herpes ace, and alleviate infection. In addition, it is proven to be good for preventing the onset and complications by showing good response to diabetic hypertension, heart disease, etc. in association with nine other ingredients of elenolic acid.
본 발명에 사용되는 기본 조성물은 연마제로서 치아에 부착된 치석 따위를 제거하며 치아에 본래의 광택을 주는 작용을 하는 주성분인 이산화규소를 사용하게 되며, 계면활성제로는 계면장력을 저하시켜 칫솔질의 청소효과를 높이고 배합되어 있는 약효제의 분산, 침투성을 도와서 그 효과를 높이는 역할을 하는 라우릴항산나 트륨을 첨가하게 되고, 세균이나 곰팡이와 같은 미생물들을 죽이는 능력을 지니고 있는 항균제로서 구강 내의 세균들을 제거하여 구강질환이나 구취를 예방 또는 억제할 수 있는 트리클로산을 사용할 수 있다. 습윤제로서 치약에 습기와 크림 상을 주기 위하여 치약이 공기 중에 접촉하여 고체화하는 것을 방지하는 역할을 하는 글리세린, 디소르비톨액, 프리필렌글리콜을 사용한다. 점도를 조절하기 위한 것으로 치약의 고체성분과 액체성분의 분리를 방지해준다 치약의 안정성을 증진시키는 성분이지만 구강 내에서의 치약의 분산성, 발포성 등에도 영향을 끼치며 수용성 고분자로 물과 알코올에 용해,분산 또는 팽창하여 고점도의 분산액을 만드는 산탄검을 사용한다. 상기 산탄검을 용해, 분산시키기 위한 에탄올이 포함된다. 구강 내 세균들의 부식성 산에 의해 치아 법랑질이 녹는 것을 방지하고 칼슘공급 촉진작용으로 치아를 튼튼하게 하는 일불소인산나트륨, 즉 불소이온은이 사용된다.The basic composition used in the present invention is to remove the tartar attached to the tooth as an abrasive and to use silicon dioxide which is a main component that gives an original gloss to the teeth, and as a surfactant, cleaning the brushing by lowering the interfacial tension It adds lauryl acid or sodium which increases the effect and helps to disperse and penetrate the compounded compound and enhances the effect, and removes bacteria in the oral cavity as an antibacterial agent that has the ability to kill microorganisms such as bacteria and fungi. Triclosan can be used to prevent or suppress oral disease or bad breath. As a humectant, glycerin, dissorbitol liquid, and pre- propylene glycol are used to prevent toothpaste from solidifying by contact with air in order to give the toothpaste moisture and creamy phase. It is to control the viscosity and prevents separation of solid and liquid components of toothpaste. It enhances the stability of toothpaste, but also affects the dispersibility and foamability of toothpaste in the oral cavity. Xanthan gum is used to disperse or swell to produce a high viscosity dispersion. Ethanol for dissolving and dispersing the xanthan gum is included. Sodium monofluorophosphate, or fluoride ion silver, is used to prevent tooth enamel from melting by corrosive acids of oral bacteria and to strengthen teeth by promoting calcium supply.
또한, 감미제로는 녹차추출물, 키토산, 프로폴리스추출물, 자일리톨, 삭카린나트륨 등을 사용한다. 녹차추출물은 휘발성 황 화합물을 제거하여 구취를 예방 및 억제할 수 있고, 키토산과 프로폴리스는 염증과 치주질환을 예방하는 효능을 지니고 있으며 잇몸 수렴작용, 잇몸재생 및 자극성 음식에 대한 민감성을 완화시켜 주어 잇몸이 붓고 치아가 시린 치은염 및 치주염 등의 치주질환발생을 억제하는 역할을 하게 된다. 향미제로서 자일리톨은 설탕과 비슷한 단맛을 내며, 뛰어난 청량감을 주면서 치아 표면의 세균막인 프라그 형성을 감소시키고 충치 예방을 가능하게 한다. 상시 삭카린나트륨은 진공속에서 승화하는 백색결정으로 약간 쓴맛이 나지만, 수크로오스의 500~700배의 감미를 가지며 냄새는 거의 없으며 에탄올에는 녹으 나 물에는 잘 녹지 않으므로 쓴맛이 적고 물에 잘 녹는 나트륨염을 감미료로 사용하게 된다.In addition, as a sweetener, green tea extract, chitosan, propolis extract, xylitol, saccharin sodium and the like are used. Green tea extract can prevent and suppress bad breath by removing volatile sulfur compounds, and chitosan and propolis have the effect of preventing inflammation and periodontal disease, and relieve gum astringent, gum regeneration and irritant food sensitivity. Swelling gums and teeth attenuate periodontal disease such as gingivitis and periodontitis. As a flavoring agent, xylitol has a sugar-like sweetness that gives it a refreshing coolness, reducing plaque formation, which is a bacterial film on the surface of teeth, and preventing tooth decay. Sodium saccharin is a white crystal that sublimates in vacuum, but has a slightly bitter taste, but it has a sweetness of 500-700 times that of sucrose, almost no smell, it is soluble in ethanol but insoluble in water, so it is less bitter and soluble in water. Will be used as a sweetener.
또한, 마그네슘을 함유하는 광물의 변질에 의하여 생성되고 매우 연질이며 촉감이 매끄러워 비누와 같은 지방감을 주는 탈크를 사용하게 된다.In addition, talc is produced by the alteration of minerals containing magnesium and is very soft and smooth to the touch, resulting in the use of talc which gives a fat like soap.
또한, 사용감을 좋게 하고 맛을 상쾌하게 하기 위하여 착향제로서 멘톨과 페파민트유를 사용하게 된다. 상기 멘톨은 박화뇌라고도 하는데 독특한 상쾌감이 있는 냄새의 무색의 침상결정으로 물에는 거의 녹지않으나 에탄올, 에테르, 클로로포름에는 잘 녹는 성질을 지니며 많은 양을 사용하면 혀를 찌르는 듯한 느낌이 있으므로 소량을 사용하여 청량감을 얻는 것이 바람직하다.In addition, menthol and peppermint oil are used as flavoring agents to improve the feeling of use and to refresh the taste. The menthol is also called thinning brain. It is a colorless acicular crystal with a unique smell. It is almost insoluble in water, but soluble in ethanol, ether, and chloroform. The menthol is used in small amounts because it feels like sticking the tongue. It is desirable to obtain a refreshing feeling.
이하, 본 발명을 하기 실시예를 통하여 더욱 구체적으로 설명한다. 그러나 이는 본 발명의 이해를 돕기 위한 것일 뿐 하기 실시예에 한정되지는 않는다.Hereinafter, the present invention will be described in more detail with reference to the following examples. However, this is only to help the understanding of the present invention and is not limited to the following examples.
(실시예) (Example)
1. 조성물(중량%)1. Composition (% by weight)
일불소인산나트륨: 0.19Sodium monofluorophosphate: 0.19
이산화규소: 15.00Silicon Dioxide: 15.00
트리클로산: 0.01Triclosan: 0.01
에탄올: 2.50Ethanol: 2.50
디소르비톨액: 45.00Dissorbitol solution: 45.00
프로필렌글리콜: 5.10Propylene Glycol: 5.10
농글리세린: 5.10Concentrated glycerin: 5.10
폴리에칠렌글리콜4000: 5.10Polyethylene glycol 4000: 5.10
산탄검: 0.50Xanthan Gum: 0.50
라우릴황산나트륨: 0.10Sodium Lauryl Sulfate: 0.10
안식향산나트륨: 0.20Sodium benzoate: 0.20
삭카린나트륨: 0.20Zaccarin Sodium: 0.20
자일리톨: 0.01Xylitol: 0.01
프로폴리스추출물: 0.01Propolis Extract: 0.01
키토산: 0.01Chitosan: 0.01
녹차추출물: 0.01Green Tea Extract: 0.01
DL-멘톨: 0.50DL-menthol: 0.50
탈크: 0.01Talc: 0.01
마이크로캡슐(올리브유 또는 올리유러핀함유 젤라틴): 0.50Microcapsules (Olive Oil or Oligoeurin-containing Gelatin): 0.50
페파민트유: 0.03Peppermint oil: 0.03
정제수: 20Purified Water: 20
기타 부가 성분: 미량Other Additional Ingredients: Trace
2. 제조공정2. Manufacturing Process
상기 조성물 중 정제수(4~12 중량%)에 습윤제(폴리에칠렌글리콜4000) 및 감미제(삭카린나트륨)을 대략 40~60℃에서 20~40분 교반하여 혼합시키는 소량분체 용해 단계를 갖는다.A small powder dissolution step of mixing the humectant (polyethylene glycol 4000) and the sweetener (saccharin sodium) at approximately 40-60 ° C. for 20-40 minutes in purified water (4-12 wt%) is mixed.
차기 단계로서 정제수(8~16 중량%)에 습윤제(디소르비톨액 및 글리세린,프로 필렌글리콜)와 부형제(탈크)를 추가하면서 대략 40~60℃에서 20~40분 교반하면서 혼합하는 습윤제 혼합단계를 갖는다.As a next step, a wetting agent mixing step of mixing while stirring for 20 to 40 minutes at 40 to 60 ° C. while adding a wetting agent (dissorbitol solution, glycerin, propylene glycol) and an excipient (talc) to purified water (8 to 16 wt%) Have
차기 단계로서 주제(일불소인산나트륨, 이산화규소, 트리클로산)와 점도조절제(산탄검)을 추가하면서 30~40℃에서 약 50~70분간 혼합하는 주 분체 혼합단계를 갖는다.As a next step, it has a main powder mixing step of mixing at a temperature of 30 to 40 ° C. for about 50 to 70 minutes while adding a main material (sodium monofluorophosphate, silicon dioxide, triclosan) and a viscosity modifier (xanthan gum).
차기 단계로서 계면활성제(라우릴황산나트륨)를 추가 투입하여 상온, 진공상태에서 20~40분간 분체를 분산 및 혼합하는 단계를 갖는다.As a next step, a surfactant (sodium lauryl sulfate) is further added to disperse and mix the powder at room temperature and vacuum for 20 to 40 minutes.
이어서, 착향제(멘톨, 페파민트유) 및 감미제(삭카린나트륨, 녹차추출물, 자일리톨, 프로폴리스추출물, 키토산)를 추가 투입한 후 부형제(올리브유 또는 올리유러핀을 내포한 젤라틴) 마이크로캡슐을 넣어 상온에서 5~20분간 진공상태 단계를 거치고 크림상태의 반제품을 완성하게 된다.Subsequently, a flavoring agent (menthol, peppermint oil) and a sweetening agent (saccharin sodium, green tea extract, xylitol, propolis extract, chitosan) are additionally added, and then an excipient (olive oil or gelatin containing oleuropine) is added to room temperature. After 5-20 minutes in a vacuum, the semi-finished product is finished.
상기 과정 중 습윤제를 혼합하는 단계, 주 분체를 혼합하는 단계 및 착향제를 첨가하는 단계에서 투입되는 각종 첨가물은 사전에 별도의 교반 용기에서 미리 혼합된 상태로 대기하고 있다가 투입하여 혼합시킴으로써 제조공정 시간을 단축함으로써 생산성을 향상시킬 수 있다.In the above process, the various additives added in the step of mixing the humectant, mixing the main powder, and adding the flavoring agent are pre-mixed in a separate stirring vessel in advance, and then mixed by adding them. By shortening the time, productivity can be improved.
상기 각 단계를 통하여 만들어진 제품은 통상의 튜브형 용기 등에 채워 완제품으로 판매하여 소비자가 사용하게 된다. Products made through each of the above steps is filled in a conventional tubular container and sold as a finished product is used by the consumer.
상기 마이크로캡슐(올리브유 또는 올리유러핀을 내포한 젤라틴)은 기본 조성물의 크림상태의 치약 내에 골고루 혼합시키는 것이 바람직하며, 상기 착향제 첨가 다음 단계에 투입하여 첨부된 도 1 및 도 2에서와 같이 백색의 불투명 또는 반투명 의 치약 조성물로부터 시각적 효과를 부여하게 되고, 이들의 입자크기를 1~5μm 범위의 것을 사용하면서 약 0.05~1 중량%, 바람직하게는 0.2~0.5 중량%의 양을 포함하도록 형성하여 상기 올리브유 또는 올리유러핀 물질을 둘러싼 젤라틴 분체(粉體)가 칫솔질 전에는 그 방출을 제어하고 있다가 사용시 녹으면서 파괴되어 치아, 잇몸 등 구강에 올리브유 또는 올리유러핀이 직접 접촉되면서 피부염과 궤양 치료 등이 가능하다.The microcapsules (olive oil or gelatin containing oleuropine) are preferably mixed evenly in the toothpaste of the cream composition of the basic composition, and added to the next step of adding the flavoring agent as shown in FIGS. 1 and 2. To give a visual effect from the opaque or translucent toothpaste composition of the, and to form a particle size of about 0.05 to 1% by weight, preferably 0.2 to 0.5% by using a particle size of 1 ~ 5μm range The gelatin powder surrounding the olive oil or oleuropine material is controlled to be discharged before brushing and is destroyed by melting during use, so that olive oil or oleuropein comes into direct contact with the oral cavity such as teeth, gums, dermatitis and ulcer treatment, etc. This is possible.
또한, 상기 마이크로캡슐은 투명한 젤라틴이지만 내포되는 올리브유 또는 올리유러핀의 고유의 색인 담황색이 가시적으로 표출되므로 미적 효과를 제공함은 물론 마이크로캡슐의 파괴를 통하여 희석되어 식별되지 않으면 양치시간 및 양호한 치솔질 상태임을 인지할 수 있다.In addition, the microcapsules are transparent gelatin, but since the inherent index pale yellow of olive oil or oliuropine contained is visually expressed, it provides aesthetic effect, and dilutes through destruction of the microcapsules, and when it is not identified, the brushing time and a good brushing state It can be recognized.
상기에서와 같은 본 발명은 치약 조성물에 함유된 마이크로캡슐(천연 올리브유 또는 올리유러핀을 내포한 젤라틴)이 녹으면서 파괴를 통해 방출되는 천연 올리브유 또는 올리유러핀의 항생성분이 구강에 직접 접촉함으로써 바이러스 세균, 곰팡이균 및 기생균을 억제하며 또 살균 효능을 통해 각종 피부염과 궤양을 치료하고 피부를 좋게 만들어주는 효과를 얻게 된다.As described above, the present invention is a microcapsules (natural olive oil or gelatin containing oleuropein) contained in the toothpaste composition, while the antibiotics of natural olive oil or oleuropeine released through the destruction by direct contact with the oral virus It inhibits bacteria, fungi and parasites, and through sterilization effect, it can treat various dermatitis and ulcers and make skin better.
또한, 올리브유 또는 올리유러핀은 인체에 전혀 해가 없으면서도 몸속의 유해한 콜레스테롤의 생성을 억제하는 불포화지방산의 함량이 식물성 기름 가운데 가장 높고 노화방지 및 성인병예방, 소화와 배변의 효과가 있음으로써 기존의 치약 조성물의 성분에 비해 더욱 강력한 구강 청결을 유지할 수 있다.In addition, olive oil or oliuropine has the highest content of unsaturated fatty acids that inhibit the production of harmful cholesterol in the body without any harm to the human body, and has the effects of anti-aging and prevention of adult diseases, digestion and defecation. Stronger oral cleanliness can be maintained compared to the components of the toothpaste composition.
본 발명의 치약은 각종 잇몸질환 효과를 제공하게 되면서, 치아를 희고 튼튼하게 하며, 구강 청결유지, 구강 내를 상쾌하게 한다. 또한, 충치예방, 구취제거, 심미효과를 높일 수 있음은 물론 치은염, 치주염(치조농루)의 예방, 치주질환예방, 잇몸질환예방, 치태제거(안티프라그)의 효과도 얻을 수 있다.Toothpaste of the present invention, while providing a variety of gum disease effects, whitening and strong teeth, maintaining oral cleanliness, refreshing the oral cavity. In addition, it is possible to prevent tooth decay, bad breath removal, aesthetic effect, as well as to prevent gingivitis, periodontitis (periodontal), periodontal disease prevention, gum disease prevention, removal of plaque (antifrag).
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KR1020050115214A KR20070065955A (en) | 2005-11-30 | 2005-11-30 | Toothpaste containing functional ingredients in microcapsules |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010070183A1 (en) * | 2008-12-18 | 2010-06-24 | Sanidad Y Residencias 21, S.A.U. | Pharmaceutical composition comprising oleuropein for utilisation in angiogenesis and vasculogenesis induction |
WO2011141611A1 (en) | 2010-05-14 | 2011-11-17 | Sanidad Y Residencias 21, S.A., | Oleuropein compositions for healing wounds and ulcers in elderly people and/or diabetics |
CN114652669A (en) * | 2022-04-22 | 2022-06-24 | 江苏雪豹日化有限公司 | Toothpaste with effects of clearing away fire and resisting allergy and preparation method thereof |
US20220226232A1 (en) * | 2021-01-21 | 2022-07-21 | Servidence Inc. | Dental formulation comprising xylitol and propolis |
-
2005
- 2005-11-30 KR KR1020050115214A patent/KR20070065955A/en not_active Ceased
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010070183A1 (en) * | 2008-12-18 | 2010-06-24 | Sanidad Y Residencias 21, S.A.U. | Pharmaceutical composition comprising oleuropein for utilisation in angiogenesis and vasculogenesis induction |
WO2011141611A1 (en) | 2010-05-14 | 2011-11-17 | Sanidad Y Residencias 21, S.A., | Oleuropein compositions for healing wounds and ulcers in elderly people and/or diabetics |
US20220226232A1 (en) * | 2021-01-21 | 2022-07-21 | Servidence Inc. | Dental formulation comprising xylitol and propolis |
CN114652669A (en) * | 2022-04-22 | 2022-06-24 | 江苏雪豹日化有限公司 | Toothpaste with effects of clearing away fire and resisting allergy and preparation method thereof |
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