KR101384748B1 - 락타미드 화합물의 제조 방법, 신규한 락타미드 화합물 및 락타미드 화합물을 함유하는 제제 - Google Patents
락타미드 화합물의 제조 방법, 신규한 락타미드 화합물 및 락타미드 화합물을 함유하는 제제 Download PDFInfo
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- KR101384748B1 KR101384748B1 KR1020087021903A KR20087021903A KR101384748B1 KR 101384748 B1 KR101384748 B1 KR 101384748B1 KR 1020087021903 A KR1020087021903 A KR 1020087021903A KR 20087021903 A KR20087021903 A KR 20087021903A KR 101384748 B1 KR101384748 B1 KR 101384748B1
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- Prior art keywords
- lactamide
- compounds
- alkyl
- formulation
- independently selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000009472 formulation Methods 0.000 title claims abstract description 40
- 239000000203 mixture Substances 0.000 title claims abstract description 40
- SXQFCVDSOLSHOQ-UHFFFAOYSA-N lactamide Chemical class CC(O)C(N)=O SXQFCVDSOLSHOQ-UHFFFAOYSA-N 0.000 title abstract description 16
- 238000000034 method Methods 0.000 title description 10
- 230000008569 process Effects 0.000 title description 4
- 150000001875 compounds Chemical class 0.000 claims abstract description 43
- 231100000419 toxicity Toxicity 0.000 claims abstract description 11
- 230000001988 toxicity Effects 0.000 claims abstract description 11
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical group [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 21
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims description 21
- 239000004094 surface-active agent Substances 0.000 claims description 6
- 241000124008 Mammalia Species 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 claims 1
- -1 lactamide compound Chemical class 0.000 abstract description 42
- 125000000217 alkyl group Chemical group 0.000 abstract description 35
- 239000002904 solvent Substances 0.000 abstract description 28
- 239000001257 hydrogen Substances 0.000 abstract description 19
- 229910052739 hydrogen Inorganic materials 0.000 abstract description 19
- 125000001424 substituent group Chemical group 0.000 abstract description 15
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 abstract description 13
- 125000002757 morpholinyl group Chemical group 0.000 abstract description 13
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract description 12
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract description 12
- 229910052757 nitrogen Inorganic materials 0.000 abstract description 10
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract description 10
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract description 8
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract description 8
- 238000004519 manufacturing process Methods 0.000 abstract description 7
- 125000003386 piperidinyl group Chemical group 0.000 abstract description 6
- 125000000719 pyrrolidinyl group Chemical group 0.000 abstract description 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract description 5
- 125000003725 azepanyl group Chemical group 0.000 abstract description 3
- 239000003905 agrochemical Substances 0.000 abstract description 2
- 239000000243 solution Substances 0.000 description 20
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 17
- 241000196324 Embryophyta Species 0.000 description 16
- 230000006378 damage Effects 0.000 description 16
- 241000238578 Daphnia Species 0.000 description 10
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 9
- 238000006243 chemical reaction Methods 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 6
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 description 5
- 150000001412 amines Chemical class 0.000 description 5
- 230000007613 environmental effect Effects 0.000 description 5
- 238000002474 experimental method Methods 0.000 description 5
- 150000002431 hydrogen Chemical class 0.000 description 5
- 239000004615 ingredient Substances 0.000 description 5
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 5
- 239000000575 pesticide Substances 0.000 description 5
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 4
- 206010040880 Skin irritation Diseases 0.000 description 4
- 231100000053 low toxicity Toxicity 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 231100000475 skin irritation Toxicity 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 240000006122 Chenopodium album Species 0.000 description 3
- 235000009344 Chenopodium album Nutrition 0.000 description 3
- 229920001213 Polysorbate 20 Polymers 0.000 description 3
- 206010059516 Skin toxicity Diseases 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 3
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
- LZCLXQDLBQLTDK-BYPYZUCNSA-N ethyl (2S)-lactate Chemical compound CCOC(=O)[C@H](C)O LZCLXQDLBQLTDK-BYPYZUCNSA-N 0.000 description 3
- 230000007794 irritation Effects 0.000 description 3
- 125000001972 isopentyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])* 0.000 description 3
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 125000001280 n-hexyl group Chemical group C(CCCCC)* 0.000 description 3
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 3
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 3
- 239000002453 shampoo Substances 0.000 description 3
- 230000036556 skin irritation Effects 0.000 description 3
- 231100000438 skin toxicity Toxicity 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 235000010823 Digitaria sanguinalis Nutrition 0.000 description 2
- 244000152970 Digitaria sanguinalis Species 0.000 description 2
- 239000004141 Sodium laurylsulphate Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000006227 byproduct Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- LZCLXQDLBQLTDK-UHFFFAOYSA-N ethyl 2-hydroxypropanoate Chemical compound CCOC(=O)C(C)O LZCLXQDLBQLTDK-UHFFFAOYSA-N 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 238000004128 high performance liquid chromatography Methods 0.000 description 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 2
- 230000004899 motility Effects 0.000 description 2
- 239000003090 pesticide formulation Substances 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000000829 suppository Substances 0.000 description 2
- 150000003512 tertiary amines Chemical class 0.000 description 2
- 239000012855 volatile organic compound Substances 0.000 description 2
- 239000001993 wax Substances 0.000 description 2
- IEORSVTYLWZQJQ-UHFFFAOYSA-N 2-(2-nonylphenoxy)ethanol Chemical compound CCCCCCCCCC1=CC=CC=C1OCCO IEORSVTYLWZQJQ-UHFFFAOYSA-N 0.000 description 1
- QOXOZONBQWIKDA-UHFFFAOYSA-N 3-hydroxypropyl Chemical group [CH2]CCO QOXOZONBQWIKDA-UHFFFAOYSA-N 0.000 description 1
- 241000251468 Actinopterygii Species 0.000 description 1
- 241000743985 Alopecurus Species 0.000 description 1
- 241000271566 Aves Species 0.000 description 1
- LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 description 1
- 241000238571 Cladocera Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 238000005033 Fourier transform infrared spectroscopy Methods 0.000 description 1
- 102000004867 Hydro-Lyases Human genes 0.000 description 1
- 108090001042 Hydro-Lyases Proteins 0.000 description 1
- RZCHTMXTKQHYDT-UHFFFAOYSA-N N-Lactoyl ethanolamine Chemical compound CC(O)C(=O)NCCO RZCHTMXTKQHYDT-UHFFFAOYSA-N 0.000 description 1
- 206010058667 Oral toxicity Diseases 0.000 description 1
- 230000000895 acaricidal effect Effects 0.000 description 1
- 239000000642 acaricide Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 125000003342 alkenyl group Chemical group 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000004061 bleaching Methods 0.000 description 1
- OOCMUZJPDXYRFD-UHFFFAOYSA-L calcium;2-dodecylbenzenesulfonate Chemical compound [Ca+2].CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O OOCMUZJPDXYRFD-UHFFFAOYSA-L 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 125000000753 cycloalkyl group Chemical group 0.000 description 1
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 description 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 238000009713 electroplating Methods 0.000 description 1
- 231100000584 environmental toxicity Toxicity 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 229940116333 ethyl lactate Drugs 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000007684 eye toxicity Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 238000002290 gas chromatography-mass spectrometry Methods 0.000 description 1
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- 239000007924 injection Substances 0.000 description 1
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- 239000000976 ink Substances 0.000 description 1
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- 229940028435 intralipid Drugs 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 125000005468 isobutylenyl group Chemical group 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- PWHWWMHNXSWQLD-UHFFFAOYSA-N n-ethyl-2-hydroxypropanamide Chemical compound CCNC(=O)C(C)O PWHWWMHNXSWQLD-UHFFFAOYSA-N 0.000 description 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 239000005645 nematicide Substances 0.000 description 1
- 229920000847 nonoxynol Polymers 0.000 description 1
- 231100000327 ocular toxicity Toxicity 0.000 description 1
- 239000003605 opacifier Substances 0.000 description 1
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- 239000003973 paint Substances 0.000 description 1
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- 231100000208 phytotoxic Toxicity 0.000 description 1
- 230000000885 phytotoxic effect Effects 0.000 description 1
- 239000005648 plant growth regulator Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 150000003141 primary amines Chemical class 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000002884 skin cream Substances 0.000 description 1
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- 239000000344 soap Substances 0.000 description 1
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- 230000003381 solubilizing effect Effects 0.000 description 1
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- 238000007920 subcutaneous administration Methods 0.000 description 1
- 150000003871 sulfonates Chemical class 0.000 description 1
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- 239000000516 sunscreening agent Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 229940034610 toothpaste Drugs 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
- 125000005208 trialkylammonium group Chemical group 0.000 description 1
- 239000002966 varnish Substances 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C233/05—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/32—Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/16—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Agronomy & Crop Science (AREA)
- Environmental Sciences (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
- Pest Control & Pesticides (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Detergent Compositions (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0605780.6A GB0605780D0 (en) | 2006-03-22 | 2006-03-22 | Formulations |
| GB0605780.6 | 2006-03-22 | ||
| PCT/GB2007/000986 WO2007107745A2 (en) | 2006-03-22 | 2007-03-21 | Process for producing lactamide compounds, new lactamide compounds and formulations containing lactamide compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20080102384A KR20080102384A (ko) | 2008-11-25 |
| KR101384748B1 true KR101384748B1 (ko) | 2014-04-14 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020087021903A Active KR101384748B1 (ko) | 2006-03-22 | 2007-03-21 | 락타미드 화합물의 제조 방법, 신규한 락타미드 화합물 및 락타미드 화합물을 함유하는 제제 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8420859B2 (https=) |
| EP (1) | EP2001288B1 (https=) |
| JP (1) | JP2009534302A (https=) |
| KR (1) | KR101384748B1 (https=) |
| CN (2) | CN104782624A (https=) |
| AR (1) | AR059925A1 (https=) |
| AU (1) | AU2007228629B2 (https=) |
| BR (1) | BRPI0708097A2 (https=) |
| CA (1) | CA2637630C (https=) |
| DK (1) | DK2001288T3 (https=) |
| EA (2) | EA017866B1 (https=) |
| ES (1) | ES2545102T3 (https=) |
| GB (1) | GB0605780D0 (https=) |
| HU (1) | HUE025333T2 (https=) |
| IL (1) | IL193060A0 (https=) |
| MX (1) | MX2008011771A (https=) |
| NO (1) | NO20083435L (https=) |
| NZ (1) | NZ569751A (https=) |
| PL (1) | PL2001288T3 (https=) |
| PT (1) | PT2001288E (https=) |
| TW (1) | TW200800016A (https=) |
| UA (1) | UA95105C2 (https=) |
| UY (1) | UY30233A1 (https=) |
| WO (1) | WO2007107745A2 (https=) |
| ZA (1) | ZA200806323B (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1961301A1 (en) * | 2007-02-22 | 2008-08-27 | Cognis IP Management GmbH | Biocide compositions comprising a dialkylamide of a hydroxycarboxylic acid |
| DE202007018968U1 (de) | 2007-02-22 | 2009-12-31 | Cognis Ip Management Gmbh | Agrochemische Zusammensetzungen mit Milchsäureverbindungen (II) |
| DE202007018967U1 (de) | 2007-02-22 | 2009-12-31 | Cognis Ip Management Gmbh | Agrochemische Zusammensetzungen mit Milchsäureverbindungen (III) |
| DE202007018969U1 (de) | 2007-02-22 | 2009-12-31 | Cognis Ip Management Gmbh | Agrochemische Zusammensetzungen mit Milchsäureverbindungen (I) |
| GB0716592D0 (en) * | 2007-08-24 | 2007-10-03 | Syngenta Ltd | Improvements in or relating to organic compounds |
| GB0716593D0 (en) * | 2007-08-24 | 2007-10-03 | Syngenta Ltd | Improvements in or relating to organic compounds |
| JP5581324B2 (ja) * | 2008-10-01 | 2014-08-27 | ピュラック バイオケム ビー． ブイ． | Ｎ，ｎ−ジアルキルラクタミドを製造する方法 |
| WO2010108814A1 (de) | 2009-03-26 | 2010-09-30 | Basf Se | Verfahren zur herstellung von n,n`-milchsäuredialkylamid unter druck |
| WO2010108817A1 (de) | 2009-03-26 | 2010-09-30 | Basf Se | Verfahren zur herstellung von n,n`-milchsäuredialkylamid über ionische flüssigkeiten |
| BR112012003255B1 (pt) * | 2009-08-11 | 2018-10-23 | Novartis Ag | processo de abertura de anel de lactonas e lactamas |
| FR2951447B1 (fr) | 2009-10-19 | 2012-10-19 | Rhodia Operations | Composes de type ether-amide et utilisattions |
| EP2387886B1 (en) | 2010-05-18 | 2016-01-06 | Cognis IP Management GmbH | Biocide compositions comprising isoamyl lactate |
| GB201012585D0 (en) * | 2010-07-27 | 2010-09-08 | Syngenta Ltd | Cleaning methods |
| GB2482299A (en) * | 2010-07-27 | 2012-02-01 | Syngenta Ltd | Use of a dialkylamide to reduce the phytotoxicity of an agrochemical |
| EP2430919B1 (en) | 2010-09-20 | 2013-06-05 | Cognis IP Management GmbH | Biocide compositions comprising amides based on 2-furoic acid and its derivatives |
| KR20120054387A (ko) * | 2010-11-19 | 2012-05-30 | 삼성정밀화학 주식회사 | 디알킬락타미드류의 제조방법 |
| EP2832735A1 (de) * | 2013-07-30 | 2015-02-04 | Sika Technology AG | Hydroxymethylcarboxamido-substituiertes Silanol für härtbare, silanterminierte Polymere. |
| PL3104699T3 (pl) * | 2014-02-14 | 2019-03-29 | BASF Agro B.V. | Koncentrat do sporządzania emulsji wodnej zawierający pestycyd, mleczan alkilu i laktamid |
| CN106170205B (zh) * | 2014-02-14 | 2020-01-17 | 巴斯夫农业公司 | 包含农药、脂肪酰胺和乳酰胺的可乳化浓缩物 |
| JP2017533892A (ja) * | 2014-10-03 | 2017-11-16 | ピュラック バイオケム ビー． ブイ． | Ｎ，ｎ−ジアルキルラクトアミドの製造法 |
| US10906012B2 (en) * | 2015-09-17 | 2021-02-02 | Basf Se | Process for making membranes |
| WO2018162554A1 (en) * | 2017-03-09 | 2018-09-13 | Basf Se | Biodegradable solvent |
| US12606569B2 (en) | 2017-06-16 | 2026-04-21 | Biotelliga Holdings Limited | Alkaloid-containing compositions and uses thereof |
| US20220369630A1 (en) * | 2021-05-06 | 2022-11-24 | Stoller Enterprises, Inc. | Stable S-(+)-Abscisic Acid Nonaqueous Liquid Solutions |
| WO2025104168A1 (en) * | 2023-11-15 | 2025-05-22 | Syngenta Crop Protection Ag | Pesticidal compositions |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4143159A (en) * | 1976-07-12 | 1979-03-06 | Henkel Kommanditgesellschaft Auf Aktien | Skin-care agents containing hydroxyalkyl carboxamides and process |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2990331A (en) * | 1956-11-23 | 1961-06-27 | Pfizer & Co C | Stable solutions of salts of tetracyclines for parenteral administration |
| DE3418167A1 (de) * | 1984-05-16 | 1985-11-21 | Bayer Ag, 5090 Leverkusen | Verwendung von amiden zur verbesserung der kulturpflanzen-vertraeglichkeit von herbizid wirksamen heteroaryloxyacetamiden |
| DE3618004A1 (de) * | 1986-05-28 | 1987-12-03 | Bayer Ag | Verwendung von amiden zur verbesserung der kulturpflanzen-vertraeglichkeit von herbizid wirksamen sulfonyliso(thio)-harnstoff-derivaten |
| DE4112873A1 (de) * | 1991-04-19 | 1992-10-22 | Richard H Dr Sehring | Fungicides pflanzenschutzmittel mit wirkung im zierpflanzen und obstbau sowie gegen echten mehltau an getreide, gurken, reben und hopfen |
| EP0719845B1 (en) * | 1994-12-27 | 1999-09-22 | Seiko Epson Corporation | Water-base ink composition and process for producing the same |
| WO2006124899A2 (en) * | 2005-05-13 | 2006-11-23 | Cargill, Incorporated | Production of derivatives of lactide, production of lactides, and use of lactide in foods and to produce polymers |
-
2006
- 2006-03-22 GB GBGB0605780.6A patent/GB0605780D0/en not_active Ceased
-
2007
- 2007-03-09 TW TW096108244A patent/TW200800016A/zh unknown
- 2007-03-16 AR ARP070101087A patent/AR059925A1/es active IP Right Grant
- 2007-03-21 US US12/293,894 patent/US8420859B2/en active Active
- 2007-03-21 EA EA201000413A patent/EA017866B1/ru not_active IP Right Cessation
- 2007-03-21 NZ NZ569751A patent/NZ569751A/en unknown
- 2007-03-21 HU HUE07732078A patent/HUE025333T2/en unknown
- 2007-03-21 KR KR1020087021903A patent/KR101384748B1/ko active Active
- 2007-03-21 WO PCT/GB2007/000986 patent/WO2007107745A2/en not_active Ceased
- 2007-03-21 CA CA2637630A patent/CA2637630C/en active Active
- 2007-03-21 EP EP07732078.6A patent/EP2001288B1/en active Active
- 2007-03-21 EA EA200870362A patent/EA016582B1/ru not_active IP Right Cessation
- 2007-03-21 AU AU2007228629A patent/AU2007228629B2/en active Active
- 2007-03-21 CN CN201510035557.3A patent/CN104782624A/zh active Pending
- 2007-03-21 JP JP2009500917A patent/JP2009534302A/ja active Pending
- 2007-03-21 PT PT77320786T patent/PT2001288E/pt unknown
- 2007-03-21 CN CNA2007800097819A patent/CN101404879A/zh active Pending
- 2007-03-21 DK DK07732078.6T patent/DK2001288T3/en active
- 2007-03-21 ES ES07732078.6T patent/ES2545102T3/es active Active
- 2007-03-21 MX MX2008011771A patent/MX2008011771A/es not_active Application Discontinuation
- 2007-03-21 PL PL07732078T patent/PL2001288T3/pl unknown
- 2007-03-21 BR BRPI0708097-2A patent/BRPI0708097A2/pt not_active Application Discontinuation
- 2007-03-21 UA UAA200812396A patent/UA95105C2/ru unknown
- 2007-03-22 UY UY30233A patent/UY30233A1/es unknown
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2008
- 2008-07-21 ZA ZA200806323A patent/ZA200806323B/xx unknown
- 2008-07-24 IL IL193060A patent/IL193060A0/en unknown
- 2008-08-05 NO NO20083435A patent/NO20083435L/no not_active Application Discontinuation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4143159A (en) * | 1976-07-12 | 1979-03-06 | Henkel Kommanditgesellschaft Auf Aktien | Skin-care agents containing hydroxyalkyl carboxamides and process |
Non-Patent Citations (2)
| Title |
|---|
| 논문 SOFW-Journal (2002) * |
| 논문 SOFW-Journal (2002)* |
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