EA200870362A1 - Способ получения производных лактамида, новые производные лактамида и препараты, содержащие производные лактамида - Google Patents

Способ получения производных лактамида, новые производные лактамида и препараты, содержащие производные лактамида

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Publication number
EA200870362A1
EA200870362A1 EA200870362A EA200870362A EA200870362A1 EA 200870362 A1 EA200870362 A1 EA 200870362A1 EA 200870362 A EA200870362 A EA 200870362A EA 200870362 A EA200870362 A EA 200870362A EA 200870362 A1 EA200870362 A1 EA 200870362A1
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EA
Eurasian Patent Office
Prior art keywords
lactamide
derivatives
6alkyl
producing
preparations
Prior art date
Application number
EA200870362A
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English (en)
Other versions
EA016582B1 (ru
Inventor
Гордон Эластэйр Белл
Ян Дэвид Тоуви
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Синджента Лимитед
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36383990&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200870362(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Синджента Лимитед filed Critical Синджента Лимитед
Publication of EA200870362A1 publication Critical patent/EA200870362A1/ru
Publication of EA016582B1 publication Critical patent/EA016582B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C233/05—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/32—Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/16—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/75—Anti-irritant

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pest Control & Pesticides (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Изобретение относится к применению производных лактамида формулы (I), где Rи R, каждый независимо, представляют собой водород; или Cалкил, Cалкенил или Сциклоалкил, каждый из которых необязательно имеет до трех заместителей, независимо выбранных из фенила, гидрокси, Cалкокси, морфолинила и NRR, где Rи R, каждый независимо, представляют собой Cалкил; или фенил, необязательно имеющий до трех заместителей, независимо выбранных из Cалкила; или Rи Rвместе с атомом азота, к которому они присоединены, образуют морфолинильное, пирролидинильное, пиперидинильное или азепанильное кольцо, каждое из которых необязательно имеет до трех заместителей, независимо выбранных из Cалкила; в препаратах для снижения токсичности, обусловленной другими компонентами препарата; к применению конкретных производных лактамида в качестве растворителей, в особенности в препаратах, конкретно в агрохимических препаратах и в экологичных препаратах; к новым производным лактамида и к способам получения производных лактамида.
EA200870362A 2006-03-22 2007-03-21 Производные лактамида, способ их получения и применение EA016582B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0605780.6A GB0605780D0 (en) 2006-03-22 2006-03-22 Formulations
PCT/GB2007/000986 WO2007107745A2 (en) 2006-03-22 2007-03-21 Process for producing lactamide compounds, new lactamide compounds and formulations containing lactamide compounds

Publications (2)

Publication Number Publication Date
EA200870362A1 true EA200870362A1 (ru) 2009-02-27
EA016582B1 EA016582B1 (ru) 2012-06-29

Family

ID=36383990

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201000413A EA017866B1 (ru) 2006-03-22 2007-03-21 Применение производных лактамида в составе препаратов для снижения токсичности
EA200870362A EA016582B1 (ru) 2006-03-22 2007-03-21 Производные лактамида, способ их получения и применение

Family Applications Before (1)

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EA201000413A EA017866B1 (ru) 2006-03-22 2007-03-21 Применение производных лактамида в составе препаратов для снижения токсичности

Country Status (25)

Country Link
US (1) US8420859B2 (ru)
EP (1) EP2001288B1 (ru)
JP (1) JP2009534302A (ru)
KR (1) KR101384748B1 (ru)
CN (2) CN101404879A (ru)
AR (1) AR059925A1 (ru)
AU (1) AU2007228629B2 (ru)
BR (1) BRPI0708097A2 (ru)
CA (1) CA2637630C (ru)
DK (1) DK2001288T3 (ru)
EA (2) EA017866B1 (ru)
ES (1) ES2545102T3 (ru)
GB (1) GB0605780D0 (ru)
HU (1) HUE025333T2 (ru)
IL (1) IL193060A0 (ru)
MX (1) MX2008011771A (ru)
NO (1) NO20083435L (ru)
NZ (1) NZ569751A (ru)
PL (1) PL2001288T3 (ru)
PT (1) PT2001288E (ru)
TW (1) TW200800016A (ru)
UA (1) UA95105C2 (ru)
UY (1) UY30233A1 (ru)
WO (1) WO2007107745A2 (ru)
ZA (1) ZA200806323B (ru)

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RU2550691C2 (ru) * 2009-08-11 2015-05-10 Новартис Аг Раскрытие циклов лактонов и лактамов

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GB0716593D0 (en) * 2007-08-24 2007-10-03 Syngenta Ltd Improvements in or relating to organic compounds
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WO2010108817A1 (de) 2009-03-26 2010-09-30 Basf Se Verfahren zur herstellung von n,n`-milchsäuredialkylamid über ionische flüssigkeiten
WO2010108814A1 (de) 2009-03-26 2010-09-30 Basf Se Verfahren zur herstellung von n,n`-milchsäuredialkylamid unter druck
FR2951447B1 (fr) 2009-10-19 2012-10-19 Rhodia Operations Composes de type ether-amide et utilisattions
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KR102626465B1 (ko) * 2015-09-17 2024-01-17 바스프 에스이 락타미드 기재 용매를 사용하는 멤브레인의 제조 방법
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WO2018229717A1 (en) * 2017-06-16 2018-12-20 Biotelliga Holdings Limited Alkaloid-containing compositions and uses thereof
US20220369630A1 (en) * 2021-05-06 2022-11-24 Stoller Enterprises, Inc. Stable S-(+)-Abscisic Acid Nonaqueous Liquid Solutions

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Also Published As

Publication number Publication date
ES2545102T3 (es) 2015-09-08
KR20080102384A (ko) 2008-11-25
US20090227453A1 (en) 2009-09-10
TW200800016A (en) 2008-01-01
AR059925A1 (es) 2008-05-07
KR101384748B1 (ko) 2014-04-14
NO20083435L (no) 2008-10-10
ZA200806323B (en) 2009-05-27
CA2637630A1 (en) 2007-09-27
US8420859B2 (en) 2013-04-16
JP2009534302A (ja) 2009-09-24
CN104782624A (zh) 2015-07-22
EP2001288B1 (en) 2015-06-24
AU2007228629B2 (en) 2013-05-16
WO2007107745A2 (en) 2007-09-27
GB0605780D0 (en) 2006-05-03
CN101404879A (zh) 2009-04-08
UA95105C2 (ru) 2011-07-11
PT2001288E (pt) 2015-10-02
EA017866B1 (ru) 2013-03-29
PL2001288T3 (pl) 2015-11-30
MX2008011771A (es) 2008-09-25
UY30233A1 (es) 2007-10-31
EA016582B1 (ru) 2012-06-29
IL193060A0 (en) 2009-08-03
NZ569751A (en) 2011-07-29
EA201000413A1 (ru) 2010-06-30
DK2001288T3 (en) 2015-08-24
WO2007107745A3 (en) 2008-07-10
BRPI0708097A2 (pt) 2011-05-17
HUE025333T2 (en) 2016-02-29
EP2001288A2 (en) 2008-12-17
CA2637630C (en) 2014-02-18
AU2007228629A1 (en) 2007-09-27

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