KR101327719B1 - 외래 항원에 대한 숙주 내성을 파괴하기 위한 키메라 항원 - Google Patents

외래 항원에 대한 숙주 내성을 파괴하기 위한 키메라 항원 Download PDF

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KR101327719B1
KR101327719B1 KR1020067002648A KR20067002648A KR101327719B1 KR 101327719 B1 KR101327719 B1 KR 101327719B1 KR 1020067002648 A KR1020067002648 A KR 1020067002648A KR 20067002648 A KR20067002648 A KR 20067002648A KR 101327719 B1 KR101327719 B1 KR 101327719B1
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KR20060089719A (ko
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라잔 조지
로른 타이렐
안토인 누자임
다쿤 왕
알란 마
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팔라딘 랩스 아이엔씨
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/385—Haptens or antigens, bound to carriers
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/19—Dendritic cells
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    • C07K16/082—Hepadnaviridae (F), e.g. hepatitis B virus
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    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
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    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6056—Antibodies
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
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    • C12N2730/10011—Hepadnaviridae
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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KR1020067002648A 2003-08-08 2004-08-06 외래 항원에 대한 숙주 내성을 파괴하기 위한 키메라 항원 Expired - Fee Related KR101327719B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49344903P 2003-08-08 2003-08-08
US60/493,449 2003-08-08
PCT/CA2004/001469 WO2005014838A1 (en) 2003-08-08 2004-08-06 Chimeric antigens for breaking host tolerance to foreign antigens

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KR1020127022397A Division KR20120102167A (ko) 2003-08-08 2004-08-06 외래 항원에 대한 숙주 내성을 파괴하기 위한 키메라 항원

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KR20060089719A KR20060089719A (ko) 2006-08-09
KR101327719B1 true KR101327719B1 (ko) 2013-11-12

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KR1020067002648A Expired - Fee Related KR101327719B1 (ko) 2003-08-08 2004-08-06 외래 항원에 대한 숙주 내성을 파괴하기 위한 키메라 항원
KR1020127022397A Ceased KR20120102167A (ko) 2003-08-08 2004-08-06 외래 항원에 대한 숙주 내성을 파괴하기 위한 키메라 항원

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US (1) US8007805B2 (enExample)
EP (2) EP2213742B1 (enExample)
JP (1) JP5200201B2 (enExample)
KR (2) KR101327719B1 (enExample)
CN (1) CN1845995B (enExample)
AU (1) AU2004263561A1 (enExample)
BR (1) BRPI0413314A (enExample)
CA (1) CA2534911C (enExample)
EA (1) EA013070B1 (enExample)
IL (1) IL173302A0 (enExample)
MX (1) MXPA06001449A (enExample)
NO (1) NO20061071L (enExample)
NZ (1) NZ545048A (enExample)
TW (1) TWI364294B (enExample)
WO (1) WO2005014838A1 (enExample)
ZA (1) ZA200600804B (enExample)

Cited By (2)

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WO2021007070A2 (en) 2019-07-09 2021-01-14 Akshaya Bio Inc. Chimeric antigens for treating viral infection
WO2026129723A1 (zh) 2024-12-20 2026-06-25 凯米生物医药(成都)有限公司 经糖基修饰的融合蛋白、核酸分子、表达载体、宿主细胞及应用

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GB0605735D0 (en) * 2006-03-22 2006-05-03 Immunobiology Ltd Composition and method for mediating an immune response
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AU2008226974B2 (en) * 2007-03-09 2013-08-15 Merck Sharp & Dohme Llc Papillomavirus vaccine compositions
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US20090305611A1 (en) * 2008-06-06 2009-12-10 Flow International Corporation Device and method for improving accuracy of a high-pressure fluid jet apparatus
CN101899419B (zh) 2009-05-25 2013-06-05 中国科学院上海生命科学研究院 昆虫杆状病毒表达系统及用其表达e2蛋白的方法
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US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
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US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
US9238679B2 (en) * 2011-02-11 2016-01-19 The Trustees Of The University Of Pennslyvania Nucleic acid molecule encoding hepatitis B virus core protein and surface antigen protein and vaccine comprising the same
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WO2012123755A1 (en) 2011-03-17 2012-09-20 The University Of Birmingham Re-directed immunotherapy
GB201203442D0 (en) 2012-02-28 2012-04-11 Univ Birmingham Immunotherapeutic molecules and uses
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KR101596364B1 (ko) * 2014-06-12 2016-02-23 중앙대학교 산학협력단 면역원성 복합 단백질을 생산하는 형질전환 식물체의 제조방법 및 이로부터 수득된 면역원성 복합 단백질
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