KR101312235B1 - 척수 손상 치료를 위한ｎ-(2-아릴-프로피오닐)-술폰아마이드의 용도 - Google Patents

척수 손상 치료를 위한ｎ-(2-아릴-프로피오닐)-술폰아마이드의 용도 Download PDF

Info

Publication number
KR101312235B1
KR101312235B1 KR1020067018031A KR20067018031A KR101312235B1 KR 101312235 B1 KR101312235 B1 KR 101312235B1 KR 1020067018031 A KR1020067018031 A KR 1020067018031A KR 20067018031 A KR20067018031 A KR 20067018031A KR 101312235 B1 KR101312235 B1 KR 101312235B1
Authority
KR
South Korea
Prior art keywords
sci
formula
treatment
aryl
propionyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020067018031A
Other languages
English (en)
Korean (ko)
Other versions
KR20070018015A (ko
Inventor
리카르도 베르티니
프란세스코 콜로타
Original Assignee
돔페 파르마 에스.피.에이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 돔페 파르마 에스.피.에이. filed Critical 돔페 파르마 에스.피.에이.
Publication of KR20070018015A publication Critical patent/KR20070018015A/ko
Application granted granted Critical
Publication of KR101312235B1 publication Critical patent/KR101312235B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020067018031A 2004-03-25 2005-03-17 척수 손상 치료를 위한ｎ-(2-아릴-프로피오닐)-술폰아마이드의 용도 Expired - Fee Related KR101312235B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04007177.1 2004-03-25
EP04007177A EP1579859B1 (en) 2004-03-25 2004-03-25 Use of N-(2-aryl-propionyl)-sulfonamides for the treatment of spinal cord injury
PCT/EP2005/002822 WO2005092315A1 (en) 2004-03-25 2005-03-17 Use of n-(2-aryl-propionyl)-sulfonamides for the treatment of spinal cord injury

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020127023407A Division KR101327150B1 (ko) 2004-03-25 2005-03-17 척수 손상 치료를 위한 ｎ-(2-아릴-프로피오닐)-술폰아마이드의 용도

Publications (2)

Publication Number Publication Date
KR20070018015A KR20070018015A (ko) 2007-02-13
KR101312235B1 true KR101312235B1 (ko) 2013-09-26

Family

ID=34854609

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020127023407A Expired - Fee Related KR101327150B1 (ko) 2004-03-25 2005-03-17 척수 손상 치료를 위한 ｎ-(2-아릴-프로피오닐)-술폰아마이드의 용도
KR1020067018031A Expired - Fee Related KR101312235B1 (ko) 2004-03-25 2005-03-17 척수 손상 치료를 위한ｎ-(2-아릴-프로피오닐)-술폰아마이드의 용도

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1020127023407A Expired - Fee Related KR101327150B1 (ko) 2004-03-25 2005-03-17 척수 손상 치료를 위한 ｎ-(2-아릴-프로피오닐)-술폰아마이드의 용도

Country Status (23)

Country Link
US (1) US20090030083A1 (enExample)
EP (1) EP1579859B1 (enExample)
JP (1) JP4988550B2 (enExample)
KR (2) KR101327150B1 (enExample)
CN (2) CN1933825A (enExample)
AT (1) ATE347883T1 (enExample)
AU (1) AU2005226901B2 (enExample)
BR (1) BRPI0509167A (enExample)
CA (1) CA2555162C (enExample)
CY (1) CY1107562T1 (enExample)
DE (1) DE602004003673T2 (enExample)
DK (1) DK1579859T3 (enExample)
ES (1) ES2279248T3 (enExample)
IL (1) IL177169A (enExample)
MX (1) MXPA06009085A (enExample)
NO (1) NO20064793L (enExample)
NZ (1) NZ548917A (enExample)
PL (1) PL1579859T3 (enExample)
PT (1) PT1579859E (enExample)
RU (1) RU2396075C2 (enExample)
SI (1) SI1579859T1 (enExample)
WO (1) WO2005092315A1 (enExample)
ZA (1) ZA200608517B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010504996A (ja) * 2006-09-26 2010-02-18 ケース ウエスタン リザーブ ユニバーシティ サイトカインシグナリング
EP2308484A1 (en) 2009-10-06 2011-04-13 Dompé S.p.a. Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets
EP2308485A1 (en) 2009-10-06 2011-04-13 Dompé S.p.a. Sulfonamides for the prevention of diabetes
CN103172547B (zh) * 2011-12-20 2016-10-12 天津市国际生物医药联合研究院 磺酰胺衍生物的制备及其应用
CN103159674A (zh) * 2013-04-03 2013-06-19 苏州安诺生物医药技术有限公司 2-苯烷酰胺类化合物及其制备方法、药物组合物和用途
KR20220064039A (ko) 2020-11-11 2022-05-18 정성삼 척수 손상 예방 또는 치료용 조성물
KR102320780B1 (ko) 2021-01-29 2021-11-02 정성삼 척추 통증 완화 및 척추 유연성 개선을 위한 조성물 및 이의 제조방법

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010086435A (ko) * 1998-10-23 2001-09-12 돔페' 써지오 Ｎ-(2-아릴-프로피오닐)-설폰아미드 및 이를 함유하는제약학적 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6419944B2 (en) * 1999-02-24 2002-07-16 Edward L. Tobinick Cytokine antagonists for the treatment of localized disorders
IT1318466B1 (it) * 2000-04-14 2003-08-25 Dompe Spa Ammidi di acidi r-2-(amminoaril)-propionici, utili nella prevenzionedell'attivazione leucocitaria.
ITMI20010206A1 (it) * 2001-02-02 2002-08-02 Dompe Spa Uso della metansolfonammide di (r)-ibuprofene e dei suoi sali non tossici per la preparazione di medicamenti per il trattamento e la prevenz

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010086435A (ko) * 1998-10-23 2001-09-12 돔페' 써지오 Ｎ-(2-아릴-프로피오닐)-설폰아미드 및 이를 함유하는제약학적 조성물

Also Published As

Publication number Publication date
US20090030083A1 (en) 2009-01-29
SI1579859T1 (sl) 2007-04-30
WO2005092315A1 (en) 2005-10-06
KR20070018015A (ko) 2007-02-13
BRPI0509167A (pt) 2007-09-11
CA2555162C (en) 2012-11-27
CY1107562T1 (el) 2013-03-13
DE602004003673D1 (de) 2007-01-25
MXPA06009085A (es) 2007-04-02
PT1579859E (pt) 2007-03-30
IL177169A (en) 2010-12-30
AU2005226901A1 (en) 2005-10-06
ES2279248T3 (es) 2007-08-16
ZA200608517B (en) 2008-04-30
ATE347883T1 (de) 2007-01-15
CN103054842A (zh) 2013-04-24
KR101327150B1 (ko) 2013-11-06
EP1579859A1 (en) 2005-09-28
DK1579859T3 (da) 2007-04-10
RU2006137575A (ru) 2008-04-27
JP4988550B2 (ja) 2012-08-01
RU2396075C2 (ru) 2010-08-10
NZ548917A (en) 2010-06-25
NO20064793L (no) 2006-10-23
PL1579859T3 (pl) 2007-06-29
DE602004003673T2 (de) 2007-10-04
JP2007530478A (ja) 2007-11-01
EP1579859B1 (en) 2006-12-13
CN1933825A (zh) 2007-03-21
IL177169A0 (en) 2006-12-10
CA2555162A1 (en) 2005-10-06
KR20120104445A (ko) 2012-09-20
AU2005226901B2 (en) 2011-06-02

Similar Documents

Publication Publication Date Title
JPH11503452A (ja) 痛みの治療のための組成物と方法
JP2004508404A (ja) 鎮痛手法
JP2003535034A (ja) ジペプチジルペプチダーゼｉｖ阻害剤並びにジペプチジルペプチダーゼｉｖ阻害剤の製造及び使用法
JP6708869B2 (ja) 神経系疾患治療剤
JP2003176240A (ja) ニコチン性アセチルコリン受容体作用薬により関節の潤滑を高める方法
JP2001513814A (ja) 小児科手術におけるレボブピバカインの使用
KR101312235B1 (ko) 척수 손상 치료를 위한ｎ-(2-아릴-프로피오닐)-술폰아마이드의 용도
JP2004523559A (ja) 過敏性腸症候群および機能性胃腸症の治療方法
WO1989010744A1 (en) Neurologically active compounds
Weigand et al. Action and toxicity of vitamin B6 hydrochloride
EP1806136B1 (en) Medicinal composition for prevention of transition to operative treatment for prostatic hypertrophy
HK1184385A (en) Use of n-(2-aryl-propionyl)-sulfonamides for the preparation of a medicament for the treatment of spinal cord injury
HK1101358A (en) Use of n-(2-aryl-propionyl)-sulfonamides for the treatment of spinal cord injury
EP4635520A1 (en) Composition for injection into joint cavity of dogs or cats comprising sodium polynucleotide
US20040204443A1 (en) Method for inducing pain relief using imidazo[1,2-a]pyridine derivatives
JP2003504396A (ja) マクロライド化合物の新規用途
Baine The Effects of Sex on Spinal Cord Injury Recovery Following Noxious Input
JP2003522792A (ja) 薬剤調製用化合物の用途
Sorbera RDP-58
JP2005053890A (ja) アディポネクチン濃度低下及び／又はｃ反応性蛋白濃度上昇及び／又はｉｌ−１８濃度上昇に起因する疾患の予防及び／又は治療剤。
MXPA01000561A (en) Therapeutic agents for allergic diseases

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E601 Decision to refuse application
PE0601 Decision on rejection of patent

St.27 status event code: N-2-6-B10-B15-exm-PE0601

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

J201 Request for trial against refusal decision
PJ0201 Trial against decision of rejection

St.27 status event code: A-3-3-V10-V11-apl-PJ0201

A107 Divisional application of patent
PA0104 Divisional application for international application

St.27 status event code: A-0-1-A10-A18-div-PA0104

St.27 status event code: A-0-1-A10-A16-div-PA0104

PJ1301 Trial decision

St.27 status event code: A-3-3-V10-V15-crt-PJ1301

Decision date: 20130613

Appeal event data comment text: Appeal Kind Category : Appeal against decision to decline refusal, Appeal Ground Text : 2006 7018031

Appeal request date: 20120809

Appellate body name: Patent Examination Board

Decision authority category: Office appeal board

Decision identifier: 2012101007235

PS0901 Examination by remand of revocation

St.27 status event code: A-6-3-E10-E12-rex-PS0901

S901 Examination by remand of revocation
GRNO Decision to grant (after opposition)
PS0701 Decision of registration after remand of revocation

St.27 status event code: A-3-4-F10-F13-rex-PS0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20160918

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20160918