CN1933825A - N－(2－芳基－丙酰基)－磺酰胺在治疗脊髓损伤上的用途 - Google Patents

N－(2－芳基－丙酰基)－磺酰胺在治疗脊髓损伤上的用途 Download PDF

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Publication number
CN1933825A
CN1933825A CNA2005800095602A CN200580009560A CN1933825A CN 1933825 A CN1933825 A CN 1933825A CN A2005800095602 A CNA2005800095602 A CN A2005800095602A CN 200580009560 A CN200580009560 A CN 200580009560A CN 1933825 A CN1933825 A CN 1933825A
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CN
China
Prior art keywords
sci
general formula
compound
alkyl
phenyl
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Pending
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CNA2005800095602A
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English (en)
Chinese (zh)
Inventor
R·贝尔蒂尼
F·科洛塔
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Dompe SpA
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Dompe PhaRMa SpA
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Application filed by Dompe PhaRMa SpA filed Critical Dompe PhaRMa SpA
Publication of CN1933825A publication Critical patent/CN1933825A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CNA2005800095602A 2004-03-25 2005-03-17 N－(2－芳基－丙酰基)－磺酰胺在治疗脊髓损伤上的用途 Pending CN1933825A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04007177.1 2004-03-25
EP04007177A EP1579859B1 (en) 2004-03-25 2004-03-25 Use of N-(2-aryl-propionyl)-sulfonamides for the treatment of spinal cord injury

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN2012104176511A Division CN103054842A (zh) 2004-03-25 2005-03-17 N-(2-芳基-丙酰基)-磺酰胺在制备治疗脊髓损伤用的药物中的用途

Publications (1)

Publication Number Publication Date
CN1933825A true CN1933825A (zh) 2007-03-21

Family

ID=34854609

Family Applications (2)

Application Number Title Priority Date Filing Date
CNA2005800095602A Pending CN1933825A (zh) 2004-03-25 2005-03-17 N－(2－芳基－丙酰基)－磺酰胺在治疗脊髓损伤上的用途
CN2012104176511A Pending CN103054842A (zh) 2004-03-25 2005-03-17 N-(2-芳基-丙酰基)-磺酰胺在制备治疗脊髓损伤用的药物中的用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN2012104176511A Pending CN103054842A (zh) 2004-03-25 2005-03-17 N-(2-芳基-丙酰基)-磺酰胺在制备治疗脊髓损伤用的药物中的用途

Country Status (23)

Country Link
US (1) US20090030083A1 (enExample)
EP (1) EP1579859B1 (enExample)
JP (1) JP4988550B2 (enExample)
KR (2) KR101327150B1 (enExample)
CN (2) CN1933825A (enExample)
AT (1) ATE347883T1 (enExample)
AU (1) AU2005226901B2 (enExample)
BR (1) BRPI0509167A (enExample)
CA (1) CA2555162C (enExample)
CY (1) CY1107562T1 (enExample)
DE (1) DE602004003673T2 (enExample)
DK (1) DK1579859T3 (enExample)
ES (1) ES2279248T3 (enExample)
IL (1) IL177169A (enExample)
MX (1) MXPA06009085A (enExample)
NO (1) NO20064793L (enExample)
NZ (1) NZ548917A (enExample)
PL (1) PL1579859T3 (enExample)
PT (1) PT1579859E (enExample)
RU (1) RU2396075C2 (enExample)
SI (1) SI1579859T1 (enExample)
WO (1) WO2005092315A1 (enExample)
ZA (1) ZA200608517B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103159674A (zh) * 2013-04-03 2013-06-19 苏州安诺生物医药技术有限公司 2-苯烷酰胺类化合物及其制备方法、药物组合物和用途
CN103172547A (zh) * 2011-12-20 2013-06-26 天津市国际生物医药联合研究院 磺酰胺衍生物的制备及其应用

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010504996A (ja) * 2006-09-26 2010-02-18 ケース ウエスタン リザーブ ユニバーシティ サイトカインシグナリング
EP2308484A1 (en) 2009-10-06 2011-04-13 Dompé S.p.a. Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets
EP2308485A1 (en) 2009-10-06 2011-04-13 Dompé S.p.a. Sulfonamides for the prevention of diabetes
KR20220064039A (ko) 2020-11-11 2022-05-18 정성삼 척수 손상 예방 또는 치료용 조성물
KR102320780B1 (ko) 2021-01-29 2021-11-02 정성삼 척추 통증 완화 및 척추 유연성 개선을 위한 조성물 및 이의 제조방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1303249B1 (it) * 1998-10-23 2000-11-06 Dompe Spa Alcune n-(2-aril-propionil)-solfonammidi e preparazionifarmaceutiche che le contengono.
US6419944B2 (en) * 1999-02-24 2002-07-16 Edward L. Tobinick Cytokine antagonists for the treatment of localized disorders
IT1318466B1 (it) * 2000-04-14 2003-08-25 Dompe Spa Ammidi di acidi r-2-(amminoaril)-propionici, utili nella prevenzionedell'attivazione leucocitaria.
ITMI20010206A1 (it) * 2001-02-02 2002-08-02 Dompe Spa Uso della metansolfonammide di (r)-ibuprofene e dei suoi sali non tossici per la preparazione di medicamenti per il trattamento e la prevenz

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103172547A (zh) * 2011-12-20 2013-06-26 天津市国际生物医药联合研究院 磺酰胺衍生物的制备及其应用
CN103172547B (zh) * 2011-12-20 2016-10-12 天津市国际生物医药联合研究院 磺酰胺衍生物的制备及其应用
CN103159674A (zh) * 2013-04-03 2013-06-19 苏州安诺生物医药技术有限公司 2-苯烷酰胺类化合物及其制备方法、药物组合物和用途

Also Published As

Publication number Publication date
US20090030083A1 (en) 2009-01-29
SI1579859T1 (sl) 2007-04-30
WO2005092315A1 (en) 2005-10-06
KR20070018015A (ko) 2007-02-13
BRPI0509167A (pt) 2007-09-11
CA2555162C (en) 2012-11-27
CY1107562T1 (el) 2013-03-13
DE602004003673D1 (de) 2007-01-25
MXPA06009085A (es) 2007-04-02
PT1579859E (pt) 2007-03-30
IL177169A (en) 2010-12-30
KR101312235B1 (ko) 2013-09-26
AU2005226901A1 (en) 2005-10-06
ES2279248T3 (es) 2007-08-16
ZA200608517B (en) 2008-04-30
ATE347883T1 (de) 2007-01-15
CN103054842A (zh) 2013-04-24
KR101327150B1 (ko) 2013-11-06
EP1579859A1 (en) 2005-09-28
DK1579859T3 (da) 2007-04-10
RU2006137575A (ru) 2008-04-27
JP4988550B2 (ja) 2012-08-01
RU2396075C2 (ru) 2010-08-10
NZ548917A (en) 2010-06-25
NO20064793L (no) 2006-10-23
PL1579859T3 (pl) 2007-06-29
DE602004003673T2 (de) 2007-10-04
JP2007530478A (ja) 2007-11-01
EP1579859B1 (en) 2006-12-13
IL177169A0 (en) 2006-12-10
CA2555162A1 (en) 2005-10-06
KR20120104445A (ko) 2012-09-20
AU2005226901B2 (en) 2011-06-02

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