KR101288258B1 - 다가불포화 지방산을 함유하는 미생물 오일의 제조방법 - Google Patents

다가불포화 지방산을 함유하는 미생물 오일의 제조방법 Download PDF

Info

Publication number
KR101288258B1
KR101288258B1 KR1020117007186A KR20117007186A KR101288258B1 KR 101288258 B1 KR101288258 B1 KR 101288258B1 KR 1020117007186 A KR1020117007186 A KR 1020117007186A KR 20117007186 A KR20117007186 A KR 20117007186A KR 101288258 B1 KR101288258 B1 KR 101288258B1
Authority
KR
South Korea
Prior art keywords
fermentation
oil
microbial oil
carbon source
ara
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
KR1020117007186A
Other languages
English (en)
Korean (ko)
Other versions
KR20110039504A (ko
Inventor
휴고 스트리크스트라
페트루스 조셉 마리아 브로켄
Original Assignee
디에스엠 아이피 어셋츠 비.브이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 디에스엠 아이피 어셋츠 비.브이. filed Critical 디에스엠 아이피 어셋츠 비.브이.
Publication of KR20110039504A publication Critical patent/KR20110039504A/ko
Application granted granted Critical
Publication of KR101288258B1 publication Critical patent/KR101288258B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings or cooking oils
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings or cooking oils
    • A23D9/02Other edible oils or fats, e.g. shortenings or cooking oils characterised by the production or working-up
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11BPRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00Production of fats or fatty oils from raw materials
    • C11B1/10Production of fats or fatty oils from raw materials by extracting
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/005Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor after treatment of microbial biomass not covered by C12N1/02 - C12N1/08
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6431Linoleic acids [18:2[n-6]]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432Eicosapentaenoic acids [EPA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434Docosahexenoic acids [DHA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6481Phosphoglycerides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Sustainable Development (AREA)
  • Animal Husbandry (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
KR1020117007186A 2002-06-19 2003-06-20 다가불포화 지방산을 함유하는 미생물 오일의 제조방법 Expired - Lifetime KR101288258B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP02254262.5 2002-06-19
EP02254262 2002-06-19
EP02258713 2002-12-18
EP02258713.3 2002-12-18
EP03251169.3 2003-02-26
EP03251169 2003-02-26
PCT/EP2003/006552 WO2004009827A2 (en) 2002-06-19 2003-06-20 Preparation of microbial oil containing polyunsaturated fatty acids

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020047020646A Division KR101208304B1 (ko) 2002-06-19 2003-06-20 다가불포화 지방산을 함유하는 미생물 오일의 제조방법

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020127028471A Division KR20120134152A (ko) 2002-06-19 2003-06-20 다가불포화 지방산을 함유하는 미생물 오일의 제조방법

Publications (2)

Publication Number Publication Date
KR20110039504A KR20110039504A (ko) 2011-04-18
KR101288258B1 true KR101288258B1 (ko) 2013-07-26

Family

ID=30773251

Family Applications (4)

Application Number Title Priority Date Filing Date
KR1020117007186A Expired - Lifetime KR101288258B1 (ko) 2002-06-19 2003-06-20 다가불포화 지방산을 함유하는 미생물 오일의 제조방법
KR1020147002810A Ceased KR20140023448A (ko) 2002-06-19 2003-06-20 다가불포화 지방산을 함유하는 미생물 오일의 제조방법
KR1020047020646A Expired - Lifetime KR101208304B1 (ko) 2002-06-19 2003-06-20 다가불포화 지방산을 함유하는 미생물 오일의 제조방법
KR1020127028471A Ceased KR20120134152A (ko) 2002-06-19 2003-06-20 다가불포화 지방산을 함유하는 미생물 오일의 제조방법

Family Applications After (3)

Application Number Title Priority Date Filing Date
KR1020147002810A Ceased KR20140023448A (ko) 2002-06-19 2003-06-20 다가불포화 지방산을 함유하는 미생물 오일의 제조방법
KR1020047020646A Expired - Lifetime KR101208304B1 (ko) 2002-06-19 2003-06-20 다가불포화 지방산을 함유하는 미생물 오일의 제조방법
KR1020127028471A Ceased KR20120134152A (ko) 2002-06-19 2003-06-20 다가불포화 지방산을 함유하는 미생물 오일의 제조방법

Country Status (14)

Country Link
US (3) US7470527B2 (https=)
EP (1) EP2333093B1 (https=)
JP (5) JP2005530519A (https=)
KR (4) KR101288258B1 (https=)
CN (3) CN100575497C (https=)
AU (1) AU2003281542A1 (https=)
BR (2) BRPI0311916B1 (https=)
CA (1) CA2489982C (https=)
DK (1) DK1513941T3 (https=)
EA (2) EA013051B1 (https=)
ES (2) ES2812475T3 (https=)
IL (1) IL165529A (https=)
MX (2) MX337781B (https=)
WO (1) WO2004009827A2 (https=)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA013051B1 (ru) * 2002-06-19 2010-02-26 ДСМ Ай Пи ЭССЕТС Б.В. Масло из микробных клеток, композиция, содержащая масло, и способ получения масла
MXPA06002028A (es) 2003-08-21 2006-05-17 Monsanto Technology Llc Desaturasas de acido graso de primula.
PL1756292T3 (pl) 2004-03-31 2015-03-31 Cargill Inc Sposób fermentacji cukrów zawierających oligomeryczne sacharydy
BRPI0509944A (pt) 2004-04-16 2007-09-25 Monsanto Technology Llc expressão de dessaturases de ácido graxo em milho
US7550286B2 (en) * 2004-11-04 2009-06-23 E. I. Du Pont De Nemours And Company Docosahexaenoic acid producing strains of Yarrowia lipolytica
WO2006052664A2 (en) 2004-11-04 2006-05-18 Monsanto Technology Llc Processes for preparation of oil compositions
BR122018075948B1 (pt) 2006-03-10 2023-05-16 Monsanto Technology Llc Métodos de produzir uma planta de soja com teor de ácidos graxos de semente alterados
KR20090007407A (ko) * 2006-04-11 2009-01-16 마텍 바이오싸이언스스 코포레이션 장쇄 다중불포화 지방산을 포함하는 식품 제품 및 그의 제조 방법
WO2008149542A1 (ja) * 2007-06-04 2008-12-11 National University Corporation Hokkaido University 微生物発酵によるdha含有リン脂質の製造方法
US20090064567A1 (en) 2007-09-12 2009-03-12 Martek Biosciences Corporation Biological oils and production and uses Thereof
EP2316278B1 (en) * 2008-08-29 2013-04-10 Pharvis R&D Korea Co., Ltd. Method for producing fermented edible plants or edible animal/plants, fermented edible plants or edible animal/plants produced by same, and foods containing same
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
US9480271B2 (en) 2009-09-15 2016-11-01 Monsanto Technology Llc Soybean seed and oil compositions and methods of making same
US9924733B2 (en) * 2010-01-19 2018-03-27 Dsm Ip Assets B.V. Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
CN107794230B (zh) * 2010-03-11 2021-10-12 帝斯曼知识产权资产管理有限公司 酵母菌株及其在脂类产生中的用途
WO2011133610A1 (en) * 2010-04-22 2011-10-27 E. I. Du Pont De Nemours And Company Method for obtaining polyunsaturated fatty acid-containing compositions from microbial biomass
JPWO2012002572A1 (ja) * 2010-06-30 2013-08-29 日本水産株式会社 有用物質の製造方法
WO2012109545A2 (en) * 2011-02-11 2012-08-16 E. I. Du Pont De Nemours And Company Method for obtaining a lipid-containing composition from microbial biomass
BR112013033455B1 (pt) 2011-06-27 2019-10-15 Dow Global Technologies Llc Fluido dielétrico e dispositivo
AU2012285806B2 (en) 2011-07-21 2017-09-14 Dsm Ip Assets B.V. Fatty acid compositions
CN103131529B (zh) * 2011-11-23 2016-02-24 丰益(上海)生物技术研发中心有限公司 一种提取微生物油脂的方法
MX358905B (es) 2011-12-30 2018-09-07 Dow Global Technologies Llc Fluido dielectrico con oligomero a base de farneseno.
BR112015012946B1 (pt) * 2012-12-10 2021-09-28 Cargill, Incorporated Processo de fermentação em lote para fermentar um hidrolisato de amido
CN105324471A (zh) * 2013-06-25 2016-02-10 国际壳牌研究有限公司 由微生物生物质生产脂肪酸酯的直接方法
EP2826384A1 (de) 2013-07-16 2015-01-21 Evonik Industries AG Verfahren zur Trocknung von Biomasse
PL3077489T3 (pl) * 2013-12-04 2021-11-08 Nippon Suisan Kaisha, Ltd. Olej drobnoustrojowy zawierający kwas dihomo-gamma-linolenowy i biomasa drobnoustrojowa zawierająca kwas dihomo-gamma-linolenowy
ES2900848T5 (en) 2014-10-02 2025-09-25 Evonik Operations Gmbh Method for preparing an animal feed
WO2016050552A1 (de) 2014-10-02 2016-04-07 Evonik Degussa Gmbh Verfahren zur herstellung einer pufas enthaltenden biomasse mit hoher zellstabilität
US10619175B2 (en) * 2014-10-02 2020-04-14 Evonik Operations Gmbh Process for producing a PUFA-containing feedstuff by extruding a PUFA-containing biomass
US11464244B2 (en) 2014-10-02 2022-10-11 Evonik Operations Gmbh Feedstuff of high abrasion resistance and good stability in water, containing PUFAs
MX390089B (es) * 2015-08-25 2025-03-20 Dsm Ip Assets Bv Composiciones de aceite refinado y métodos para su elaboración.
JP6998935B2 (ja) 2016-07-13 2022-01-18 エボニック オペレーションズ ゲーエムベーハー 溶解された脂質含有バイオマスから脂質を分離する方法
RU2744913C2 (ru) 2016-12-27 2021-03-17 Эвоник Оперейшенс ГмбХ Способ выделения липидов из липидсодержащей биомассы
WO2019030147A1 (en) * 2017-08-07 2019-02-14 Dsm Ip Assets B.V. PROCESS FOR PRODUCTION OF CONCENTRATED OILS OF POLYUNSATURATED FATTY ACIDS
EP3470502A1 (en) 2017-10-13 2019-04-17 Evonik Degussa GmbH Method of separating lipids from a lysed lipids containing biomass
EP3527664A1 (en) 2018-02-15 2019-08-21 Evonik Degussa GmbH Method of isolating lipids from a lipids containing biomass
WO2019191544A1 (en) * 2018-03-30 2019-10-03 Dsm Ip Assets B.V. Method of obtaining a microbial oil and a method of reducing emulsion by maintaining a low concentration of carbohydrate
EP3794097B1 (en) 2018-05-15 2024-10-23 Evonik Operations GmbH Method of isolating lipids from a lipids containing biomass with aid of hydrophobic silica
WO2019219396A1 (en) 2018-05-15 2019-11-21 Evonik Operations Gmbh Method of isolating lipids from a lysed lipids containing biomass by emulsion inversion
CN108902364A (zh) * 2018-08-04 2018-11-30 望江县振兴植物油厂(普通合伙) 一种儿童专用调和油及其制备方法
CA3116718A1 (en) * 2018-10-17 2020-04-23 Perfect Day, Inc. Recombinant components and compositions for use in food products
CN110747239B (zh) * 2019-11-26 2021-06-22 瞿瀚鹏 富含Sn-2位ARA的微生物油脂及其制备方法和应用
CN111575110A (zh) * 2020-05-27 2020-08-25 嘉必优生物技术(武汉)股份有限公司 一种含有多不饱和脂肪酸的微生物油脂的纯化方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0213388A (ja) * 1988-06-30 1990-01-17 Lion Corp 不飽和脂肪酸含有脂質の製造方法
US5658767A (en) * 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0716424B2 (ja) 1985-10-01 1995-03-01 ライオン株式会社 アラキドン酸含有脂質の製造方法
JPS6438007A (en) * 1987-04-28 1989-02-08 Lion Corp Skin external preparation
JP2723243B2 (ja) * 1988-02-25 1998-03-09 サントリー株式会社 高度不飽和脂肪酸添加動物飼料
JPH01228486A (ja) * 1988-03-09 1989-09-12 Suntory Ltd 奇数鎖高度不飽和脂肪酸及びこれを含有する脂質の製造方法
JPH02142486A (ja) 1988-11-25 1990-05-31 Lion Corp 不飽和脂肪酸含有脂質の製造方法
PH11992043811B1 (en) 1991-01-24 2002-08-22 Martek Corp Arachidonic acid and methods for the production and use thereof
JP3354582B2 (ja) * 1991-09-30 2002-12-09 サントリー株式会社 オメガ9系高度不飽和脂肪酸およびこれを含有する脂質の製造方法
US5583019A (en) * 1995-01-24 1996-12-10 Omegatech Inc. Method for production of arachidonic acid
CN1217029A (zh) * 1996-03-28 1999-05-19 吉斯特-布罗卡迪斯股份有限公司 从用巴氏法灭菌的生物量中制备含有微生物多不饱和脂肪酸的油的方法
US6746857B2 (en) * 1996-12-27 2004-06-08 Suntory Limited Media for culturing microorganisms and process for producing unsaturated fatty acids or lipids containing the same
JP2000069987A (ja) * 1998-08-28 2000-03-07 Suntory Ltd アラキドン酸含有脂質並びにジホモ−γ−リノレン酸含有脂質の製造方法
CN1074289C (zh) * 1999-04-14 2001-11-07 内蒙古美乐绿色食品开发公司 具有抑制肿瘤和免疫调节功能的口服液
EP1178103A1 (en) 2000-08-02 2002-02-06 Dsm N.V. Purifying crude pufa oils
DE50113264D1 (de) * 2001-03-08 2007-12-27 Enthone System zur elektrodialytischen Regeneration eines stromlosen Badelektrolyten
CN1362522A (zh) * 2001-12-26 2002-08-07 武汉烯王生物工程有限公司 用离子束生物工程诱变菌生产含花生四烯酸油脂的方法
EA013051B1 (ru) 2002-06-19 2010-02-26 ДСМ Ай Пи ЭССЕТС Б.В. Масло из микробных клеток, композиция, содержащая масло, и способ получения масла

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0213388A (ja) * 1988-06-30 1990-01-17 Lion Corp 不飽和脂肪酸含有脂質の製造方法
US5658767A (en) * 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof

Also Published As

Publication number Publication date
MXPA04012915A (es) 2005-03-31
US20140017742A1 (en) 2014-01-16
EA200500048A1 (ru) 2005-06-30
JP2009261397A (ja) 2009-11-12
DK1513941T3 (en) 2016-04-18
US7470527B2 (en) 2008-12-30
JP6226601B2 (ja) 2017-11-08
EA013051B1 (ru) 2010-02-26
KR20050021984A (ko) 2005-03-07
KR20110039504A (ko) 2011-04-18
KR20140023448A (ko) 2014-02-26
JP2011024582A (ja) 2011-02-10
IL165529A (en) 2010-05-31
EP2333093A1 (en) 2011-06-15
BR0311916A (pt) 2005-03-29
JP2016127837A (ja) 2016-07-14
WO2004009827A2 (en) 2004-01-29
AU2003281542A1 (en) 2004-02-09
CA2489982A1 (en) 2004-01-29
EP2333093B1 (en) 2020-06-10
KR20120134152A (ko) 2012-12-11
MX337781B (es) 2016-03-16
IL165529A0 (en) 2006-01-15
CA2489982C (en) 2019-09-10
ES2567569T3 (es) 2016-04-25
US20090053342A1 (en) 2009-02-26
KR101208304B1 (ko) 2012-12-05
JP2005530519A (ja) 2005-10-13
US10633678B2 (en) 2020-04-28
BRPI0311916B1 (pt) 2020-01-28
CN112280807A (zh) 2021-01-29
EA200901291A1 (ru) 2010-02-26
JP2014039540A (ja) 2014-03-06
CN1662654A (zh) 2005-08-31
AU2003281542A8 (en) 2004-02-09
CN101787379A (zh) 2010-07-28
US20050202148A1 (en) 2005-09-15
CN100575497C (zh) 2009-12-30
ES2812475T3 (es) 2021-03-17
WO2004009827A3 (en) 2004-04-15

Similar Documents

Publication Publication Date Title
KR101288258B1 (ko) 다가불포화 지방산을 함유하는 미생물 오일의 제조방법
EP1513941B1 (en) Preparation of microbial oil containing polyunsaturated fatty acids
DK2267142T3 (en) Process for the preparation of microbial fat or oil of reduced non-sealable content and the fat or oil
KR20140146156A (ko) 다가불포화 지방산을 함유하는 미생물 오일의 제조방법
HK1146736A (en) Preparation of microbial oil containing polyunsaturated fatty acids
HK1158697A (en) Preparation of microbial oil containing polyunsaturated fatty acids
HK1152549A (en) Preparation of microbial oil containing polyunsaturated fatty acids
EA039406B1 (ru) Способ пастеризации микробных клеток и масла из микробных клеток

Legal Events

Date Code Title Description
A107 Divisional application of patent
A201 Request for examination
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20110328

PA0201 Request for examination
PG1501 Laying open of application
E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20110604

Patent event code: PE09021S01D

AMND Amendment
E90F Notification of reason for final refusal
PE0902 Notice of grounds for rejection

Comment text: Final Notice of Reason for Refusal

Patent event date: 20120430

Patent event code: PE09021S02D

A107 Divisional application of patent
AMND Amendment
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20121030

E601 Decision to refuse application
E801 Decision on dismissal of amendment
PE0601 Decision on rejection of patent

Patent event date: 20121116

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20120430

Comment text: Final Notice of Reason for Refusal

Patent event code: PE06011S02I

Patent event date: 20110604

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

PE0801 Dismissal of amendment

Patent event code: PE08012E01D

Comment text: Decision on Dismissal of Amendment

Patent event date: 20121116

Patent event code: PE08011R01I

Comment text: Amendment to Specification, etc.

Patent event date: 20121030

Patent event code: PE08011R01I

Comment text: Amendment to Specification, etc.

Patent event date: 20111205

J201 Request for trial against refusal decision
PJ0201 Trial against decision of rejection

Patent event date: 20130219

Comment text: Request for Trial against Decision on Refusal

Patent event code: PJ02012R01D

Patent event date: 20121116

Comment text: Decision to Refuse Application

Patent event code: PJ02011S01I

Appeal kind category: Appeal against decision to decline refusal

Decision date: 20130415

Appeal identifier: 2013101001171

Request date: 20130219

AMND Amendment
PB0901 Examination by re-examination before a trial

Comment text: Amendment to Specification, etc.

Patent event date: 20130321

Patent event code: PB09011R02I

Comment text: Request for Trial against Decision on Refusal

Patent event date: 20130219

Patent event code: PB09011R01I

Comment text: Amendment to Specification, etc.

Patent event date: 20121030

Patent event code: PB09011R02I

Comment text: Amendment to Specification, etc.

Patent event date: 20111205

Patent event code: PB09011R02I

B701 Decision to grant
PB0701 Decision of registration after re-examination before a trial

Patent event date: 20130415

Comment text: Decision to Grant Registration

Patent event code: PB07012S01D

Patent event date: 20130329

Comment text: Transfer of Trial File for Re-examination before a Trial

Patent event code: PB07011S01I

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20130715

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20130715

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
FPAY Annual fee payment

Payment date: 20160616

Year of fee payment: 4

PR1001 Payment of annual fee

Payment date: 20160616

Start annual number: 4

End annual number: 4

FPAY Annual fee payment

Payment date: 20170616

Year of fee payment: 5

PR1001 Payment of annual fee

Payment date: 20170616

Start annual number: 5

End annual number: 5

FPAY Annual fee payment

Payment date: 20190617

Year of fee payment: 7

PR1001 Payment of annual fee

Payment date: 20190617

Start annual number: 7

End annual number: 7

PR1001 Payment of annual fee

Payment date: 20200618

Start annual number: 8

End annual number: 8

PC1801 Expiration of term

Termination date: 20231220

Termination category: Expiration of duration