KR101238461B1 - 항바이러스성 뉴클레오시드 - Google Patents

항바이러스성 뉴클레오시드 Download PDF

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Publication number
KR101238461B1
KR101238461B1 KR1020087016625A KR20087016625A KR101238461B1 KR 101238461 B1 KR101238461 B1 KR 101238461B1 KR 1020087016625 A KR1020087016625 A KR 1020087016625A KR 20087016625 A KR20087016625 A KR 20087016625A KR 101238461 B1 KR101238461 B1 KR 101238461B1
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South Korea
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hcv
compound
acid
nucleoside
unbranched
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Korean (ko)
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KR20080079671A (ko
Inventor
전병권
제레미 클라크
케샵 사르마
페이유안 왕
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길리어드 파마셋 엘엘씨
에프. 호프만-라 로슈 아게
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Application filed by 길리어드 파마셋 엘엘씨, 에프. 호프만-라 로슈 아게 filed Critical 길리어드 파마셋 엘엘씨
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12—Triazine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
KR1020087016625A 2005-12-09 2006-11-29 항바이러스성 뉴클레오시드 Expired - Fee Related KR101238461B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74931905P 2005-12-09 2005-12-09
US60/749,319 2005-12-09
PCT/EP2006/069060 WO2007065829A1 (en) 2005-12-09 2006-11-29 Antiviral nucleosides

Publications (2)

Publication Number Publication Date
KR20080079671A KR20080079671A (ko) 2008-09-01
KR101238461B1 true KR101238461B1 (ko) 2013-03-05

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KR1020087016625A Expired - Fee Related KR101238461B1 (ko) 2005-12-09 2006-11-29 항바이러스성 뉴클레오시드

Country Status (25)

Country Link
US (1) US7754699B2 (https=)
EP (1) EP1957510A1 (https=)
JP (2) JP4979710B2 (https=)
KR (1) KR101238461B1 (https=)
CN (1) CN101336247B (https=)
AR (1) AR056850A1 (https=)
AU (1) AU2006324098C1 (https=)
BR (1) BRPI0619563A2 (https=)
CA (1) CA2632626C (https=)
CR (1) CR10136A (https=)
EC (1) ECSP088518A (https=)
GT (1) GT200800095A (https=)
HN (1) HN2006041184A (https=)
IL (1) IL192002A0 (https=)
MA (1) MA30057B1 (https=)
MY (1) MY150667A (https=)
NO (1) NO20082934L (https=)
NZ (1) NZ568909A (https=)
PE (1) PE20071131A1 (https=)
RU (1) RU2422454C2 (https=)
TW (1) TWI394759B (https=)
UA (1) UA91255C2 (https=)
UY (1) UY30004A1 (https=)
WO (1) WO2007065829A1 (https=)
ZA (1) ZA200804958B (https=)

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MY150667A (en) 2014-02-28
AU2006324098B2 (en) 2011-02-24
GT200800095A (es) 2009-10-08
CR10136A (es) 2008-11-18
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CA2632626A1 (en) 2007-06-14
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CA2632626E (en) 2007-06-14
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AR056850A1 (es) 2007-10-24
AU2006324098A1 (en) 2007-06-14
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UA91255C2 (uk) 2010-07-12
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CA2632626C (en) 2011-10-11
MA30057B1 (fr) 2008-12-01
US7754699B2 (en) 2010-07-13
ZA200804958B (en) 2009-05-27
UY30004A1 (es) 2007-06-29
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RU2008127750A (ru) 2010-01-20
US20070197463A1 (en) 2007-08-23
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