KR101125818B1 - 포스포릴콜린기 함유 화합물 및 이 화합물로 이루어지는표면 개질제 - Google Patents

포스포릴콜린기 함유 화합물 및 이 화합물로 이루어지는표면 개질제 Download PDF

Info

Publication number
KR101125818B1
KR101125818B1 KR1020067003059A KR20067003059A KR101125818B1 KR 101125818 B1 KR101125818 B1 KR 101125818B1 KR 1020067003059 A KR1020067003059 A KR 1020067003059A KR 20067003059 A KR20067003059 A KR 20067003059A KR 101125818 B1 KR101125818 B1 KR 101125818B1
Authority
KR
South Korea
Prior art keywords
group
compound
formula
powder
phosphorylcholine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
KR1020067003059A
Other languages
English (en)
Korean (ko)
Other versions
KR20060121810A (ko
Inventor
요우스케 도우조
가즈유키 미야자와
다케토시 간다
히로시 구츠나
겐이치 사쿠마
마사요시 와다
유키미츠 스다
Original Assignee
가부시키가이샤 시세이도
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 가부시키가이샤 시세이도 filed Critical 가부시키가이샤 시세이도
Publication of KR20060121810A publication Critical patent/KR20060121810A/ko
Application granted granted Critical
Publication of KR101125818B1 publication Critical patent/KR101125818B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004Sorbent size or size distribution, e.g. particle size
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016Particle form
    • B01J20/28019Spherical, ellipsoidal or cylindrical
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28057Surface area, e.g. B.E.T specific surface area
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078Pore diameter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/289Phases chemically bonded to a substrate, e.g. to silica or to polymers bonded via a spacer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/3092Packing of a container, e.g. packing a cartridge or column
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204Inorganic carriers, supports or substrates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244Non-macromolecular compounds
    • B01J20/3246Non-macromolecular compounds having a well defined chemical structure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244Non-macromolecular compounds
    • B01J20/3246Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3257Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244Non-macromolecular compounds
    • B01J20/3246Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3257Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such
    • B01J20/3259Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such comprising at least two different types of heteroatoms selected from nitrogen, oxygen or sulfur with at least one silicon atom
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/56Labware specially adapted for transferring fluids
    • B01L3/569Glassware
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F19/00Metal compounds according to more than one of main groups C07F1/00 - C07F17/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/091Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54Sorbents specially adapted for analytical or investigative chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/58Use in a single column
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • B01L2300/161Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/163Biocompatibility

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Inorganic Chemistry (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Filtering Materials (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
KR1020067003059A 2003-12-02 2004-12-01 포스포릴콜린기 함유 화합물 및 이 화합물로 이루어지는표면 개질제 Expired - Lifetime KR101125818B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2003402725 2003-12-02
JPJP-P-2003-00402725 2003-12-02
JPJP-P-2004-00345739 2004-11-30
JP2004345739A JP4086305B2 (ja) 2003-12-02 2004-11-30 ホスホリルコリン基含有化合物及び該化合物からなる表面改質剤
PCT/JP2004/017835 WO2005054262A1 (ja) 2003-12-02 2004-12-01 ホスホリルコリン基含有化合物及び該化合物からなる表面改質剤

Publications (2)

Publication Number Publication Date
KR20060121810A KR20060121810A (ko) 2006-11-29
KR101125818B1 true KR101125818B1 (ko) 2012-03-27

Family

ID=34656198

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067003059A Expired - Lifetime KR101125818B1 (ko) 2003-12-02 2004-12-01 포스포릴콜린기 함유 화합물 및 이 화합물로 이루어지는표면 개질제

Country Status (6)

Country Link
US (2) US7906670B2 (https=)
EP (1) EP1690867B1 (https=)
JP (1) JP4086305B2 (https=)
KR (1) KR101125818B1 (https=)
TW (1) TW200524947A (https=)
WO (1) WO2005054262A1 (https=)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4086305B2 (ja) * 2003-12-02 2008-05-14 株式会社資生堂 ホスホリルコリン基含有化合物及び該化合物からなる表面改質剤
JP4591926B2 (ja) * 2004-05-21 2010-12-01 株式会社資生堂 素材の表面改質方法
JP3852942B2 (ja) * 2004-05-24 2006-12-06 株式会社資生堂 水中分散性化粧料用粉体
JP3715308B1 (ja) * 2004-05-24 2005-11-09 株式会社資生堂 眼用レンズ材料及びその製造方法
US7402243B2 (en) 2004-09-10 2008-07-22 Dionex Corporation Organosilanes and substrate bonded with same
DE602005022345D1 (de) * 2004-11-29 2010-08-26 Shiseido Co Ltd Eine phosphorylcholingruppe enthaltende verbindung, und verfahren zu ihrer herstellung
JP5013575B2 (ja) * 2005-10-28 2012-08-29 株式会社 資生堂 素材の表面処理方法
KR100966627B1 (ko) 2006-06-14 2010-06-29 주식회사 대웅제약 L-α-글리세로포스포릴 콜린의 제조방법
JP4809150B2 (ja) * 2006-07-25 2011-11-09 株式会社 資生堂 ガラス製品、分析装置及び分析方法
JP4993347B2 (ja) * 2006-12-13 2012-08-08 株式会社 資生堂 ホスホリルコリン基含有シラン化合物の製造方法
JP4191225B2 (ja) 2007-01-18 2008-12-03 株式会社資生堂 表面改質方法及び表面改質材料
JP5280664B2 (ja) * 2007-10-25 2013-09-04 株式会社 資生堂 表面改質方法及び表面改質材料
JP5173691B2 (ja) * 2008-09-17 2013-04-03 株式会社 資生堂 親水性相互作用クロマトグラフィー用充填剤
JP5248257B2 (ja) * 2008-10-01 2013-07-31 積水メディカル株式会社 イオン交換液体クロマトグラフィーを用いた蛋白質の分析方法、及び、ヘモグロビン類の分離、定量方法
EP2405267A1 (en) * 2009-03-02 2012-01-11 Shiseido Co., Ltd. Surface-modified base plate, biochip and process for producing the biochip
WO2010147122A1 (ja) 2009-06-15 2010-12-23 株式会社資生堂 細胞凝集塊形成用容器及び細胞凝集塊の形成方法
US8845546B2 (en) * 2010-02-18 2014-09-30 Devicor Medical Products, Inc. Biopsy device tissue sample holder with flow restriction device
JP5751578B2 (ja) * 2011-04-27 2015-07-22 国立研究開発法人産業技術総合研究所 ホスホリルコリン−シラン化合物表面修飾材料
JP5853855B2 (ja) * 2012-05-10 2016-02-09 日油株式会社 カルボキシル基含有ホスホリルコリン化合物及びその製造方法
WO2013176084A1 (ja) * 2012-05-22 2013-11-28 日産化学工業株式会社 シリルアルキルホスホラミダード化合物を含むシランカップリング剤
EP2812091B1 (en) * 2012-09-17 2021-03-10 W.R. Grace & CO. - CONN. Chromatography media and devices
EP2860183B1 (en) * 2013-03-25 2018-04-25 Sumitomo Riko Company Limited Reactive ionic liquid and ion-immobilized metal oxide particles produced using same, ion-immobilized elastomer, and transducer
JP6291820B2 (ja) * 2013-12-06 2018-03-14 日油株式会社 シリル基含有ホスホリルコリン化合物及びその製造方法、並びに、重縮合体及び表面改質剤
PL3137209T3 (pl) 2014-05-02 2023-01-02 W.R. Grace & Co. - Conn. Funkcjonalizowany materiał nośnikowy i sposoby wytwarzania oraz stosowania funkcjonalizowanego materiału nośnikowego
US9340562B1 (en) * 2014-10-29 2016-05-17 Thermo Electron Manufacturing Limited Chromatographic material and method for preparation thereof
JP6395183B2 (ja) * 2015-01-29 2018-09-26 京都府公立大学法人 陰イオン交換能を発現する両性イオン導入樹脂
JP6395184B2 (ja) * 2015-01-29 2018-09-26 京都府公立大学法人 陽イオン交換能を発現する両性イオン導入樹脂
JP2021121411A (ja) * 2018-04-16 2021-08-26 Agc株式会社 サイズ排除クロマトグラフィ担体、その製造方法、および微小物質の回収方法
CN110215740B (zh) * 2019-07-15 2021-05-04 大连医科大学 一种两性离子亲水前处理硅胶材料的制备方法
JP2022540707A (ja) * 2019-07-19 2022-09-16 アカテコール・インコーポレイテッド 分子的に十分に規定された生物付着防止ポリイオンコーティング
CN111250069B (zh) * 2020-01-20 2022-03-04 浙江月旭材料科技有限公司 硅胶色谱填料及其制备方法和应用
CN117836353A (zh) 2021-08-31 2024-04-05 日油株式会社 具有磷酰胆碱基和羟基的含聚二甲基硅氧烷单体
WO2023113031A1 (ja) * 2021-12-17 2023-06-22 Agc株式会社 フィルター、フィルターの製造方法、コーティング材、微小物質捕捉用器具、微小物質検出装置、微小物質捕捉方法及び化合物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000279512A (ja) * 1999-03-30 2000-10-10 Nof Corp 医療用材料および製造方法
JP2002098676A (ja) * 2000-09-22 2002-04-05 Kazuhiko Ishihara 分離材及び分離・回収方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8401534D0 (en) * 1984-01-20 1984-02-22 Royal Free Hosp School Med Biocompatible surfaces
DE4026029A1 (de) * 1989-09-07 1992-02-20 Sandoz Ag Waessrige aminopolysiloxanmikroemulsionen, deren herstellung und verwendung
WO2004048492A1 (ja) * 2002-11-25 2004-06-10 Shiseido Company, Ltd. 素材の表面改質方法
JP3655615B2 (ja) * 2003-02-28 2005-06-02 株式会社資生堂 クロマトグラフィー用充填剤
JP4245336B2 (ja) * 2002-11-25 2009-03-25 株式会社資生堂 ホスホリルコリン基を有するポリシロキサン及びその製造方法
JP4086305B2 (ja) * 2003-12-02 2008-05-14 株式会社資生堂 ホスホリルコリン基含有化合物及び該化合物からなる表面改質剤
JP3715308B1 (ja) 2004-05-24 2005-11-09 株式会社資生堂 眼用レンズ材料及びその製造方法
JP3852942B2 (ja) 2004-05-24 2006-12-06 株式会社資生堂 水中分散性化粧料用粉体

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000279512A (ja) * 1999-03-30 2000-10-10 Nof Corp 医療用材料および製造方法
JP2002098676A (ja) * 2000-09-22 2002-04-05 Kazuhiko Ishihara 分離材及び分離・回収方法

Also Published As

Publication number Publication date
EP1690867A4 (en) 2009-08-12
US7906670B2 (en) 2011-03-15
TWI364426B (https=) 2012-05-21
WO2005054262A1 (ja) 2005-06-16
JP4086305B2 (ja) 2008-05-14
US8426627B2 (en) 2013-04-23
EP1690867B1 (en) 2013-10-16
JP2005187456A (ja) 2005-07-14
EP1690867A1 (en) 2006-08-16
TW200524947A (en) 2005-08-01
US20080214855A1 (en) 2008-09-04
KR20060121810A (ko) 2006-11-29
US20110130583A1 (en) 2011-06-02

Similar Documents

Publication Publication Date Title
KR101125818B1 (ko) 포스포릴콜린기 함유 화합물 및 이 화합물로 이루어지는표면 개질제
US7560023B2 (en) Method of modifying surface of material
CN102124330B (zh) 亲水性相互作用色谱用填充剂
JP4440474B2 (ja) クロマトグラフィー分離法および選択吸着体
JP4869247B2 (ja) 混合様式アニオン交換型分離材料
JP2019516969A (ja) 荷電表面逆相クロマトグラフィ材料による両親媒性強塩基性部分で修飾されたグリカンの分析方法
Bäurer et al. Stable-bond polymeric reversed-phase/weak anion-exchange mixed-mode stationary phases obtained by simultaneous functionalization and crosslinking of a poly (3-mercaptopropyl) methylsiloxane-film on vinyl silica via thiol-ene double click reaction
JPS6345558A (ja) 逆相充▲てん▼材料
CN100549018C (zh) 含有磷酸胆碱基的化合物及包含该化合物的表面改性剂
Karakoç et al. Affinity adsorption of recombinant human interferon-α on a porous dye-affinity adsorbent
EP1973143A1 (en) Process for the sample preparation of biomolecules prior to ms
HK1155517B (en) Filler for hydrophilic interaction chromatography
HK1155517A (en) Filler for hydrophilic interaction chromatography
JP4182789B2 (ja) 生体試料由来の検査液に含まれる低分子量タンパク質の電気泳動法による分析方法及びその利用
JPH04213056A (ja) 物質分画法および分画装置

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20060214

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20091102

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20110621

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20120222

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20120305

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20120306

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
FPAY Annual fee payment

Payment date: 20150224

Year of fee payment: 4

PR1001 Payment of annual fee

Payment date: 20150224

Start annual number: 4

End annual number: 4

FPAY Annual fee payment

Payment date: 20160218

Year of fee payment: 5

PR1001 Payment of annual fee

Payment date: 20160218

Start annual number: 5

End annual number: 5

FPAY Annual fee payment

Payment date: 20170220

Year of fee payment: 6

PR1001 Payment of annual fee

Payment date: 20170220

Start annual number: 6

End annual number: 6

FPAY Annual fee payment

Payment date: 20180219

Year of fee payment: 7

PR1001 Payment of annual fee

Payment date: 20180219

Start annual number: 7

End annual number: 7

FPAY Annual fee payment

Payment date: 20190218

Year of fee payment: 8

PR1001 Payment of annual fee

Payment date: 20190218

Start annual number: 8

End annual number: 8

FPAY Annual fee payment

Payment date: 20200218

Year of fee payment: 9

PR1001 Payment of annual fee

Payment date: 20200218

Start annual number: 9

End annual number: 9

FPAY Annual fee payment

Payment date: 20210226

Year of fee payment: 10

PR1001 Payment of annual fee

Payment date: 20210226

Start annual number: 10

End annual number: 10

FPAY Annual fee payment

Payment date: 20220223

Year of fee payment: 11

PR1001 Payment of annual fee

Payment date: 20220223

Start annual number: 11

End annual number: 11

PR1001 Payment of annual fee

Payment date: 20240226

Start annual number: 13

End annual number: 13

PC1801 Expiration of term

Termination date: 20250601

Termination category: Expiration of duration