KR100919927B1 - 멜록시캄의 신규한 결정형 그리고 그들의 제조 및상호전환 방법 - Google Patents

멜록시캄의 신규한 결정형 그리고 그들의 제조 및상호전환 방법 Download PDF

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KR100919927B1
KR100919927B1 KR1020047008796A KR20047008796A KR100919927B1 KR 100919927 B1 KR100919927 B1 KR 100919927B1 KR 1020047008796 A KR1020047008796 A KR 1020047008796A KR 20047008796 A KR20047008796 A KR 20047008796A KR 100919927 B1 KR100919927 B1 KR 100919927B1
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South Korea
Prior art keywords
meloxycam
water
temperature
meloxycham
precipitate
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Expired - Fee Related
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English (en)
Korean (ko)
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KR20040082380A (ko
Inventor
라우 코피
마르티 바르트라 산-마르티
몬트세라트 클로사 칼보
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에스티브 퀴미카 에스.에이.
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Publication of KR20040082380A publication Critical patent/KR20040082380A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
KR1020047008796A 2001-12-11 2002-11-19 멜록시캄의 신규한 결정형 그리고 그들의 제조 및상호전환 방법 Expired - Fee Related KR100919927B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200102743A ES2223209B1 (es) 2001-12-11 2001-12-11 Nuevas formas cristalinas del meloxicam y procedimientos para su preparacion e interconversion.
ESP0102743 2001-12-11
PCT/ES2002/000539 WO2003057692A1 (es) 2001-12-11 2002-11-19 Nuevas formas cristalinas del meloxicam y procedimientos para su preparacion e interconversion

Publications (2)

Publication Number Publication Date
KR20040082380A KR20040082380A (ko) 2004-09-24
KR100919927B1 true KR100919927B1 (ko) 2009-10-07

Family

ID=8499703

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KR1020047008796A Expired - Fee Related KR100919927B1 (ko) 2001-12-11 2002-11-19 멜록시캄의 신규한 결정형 그리고 그들의 제조 및상호전환 방법

Country Status (18)

Country Link
US (1) US6967248B2 (enExample)
EP (1) EP1462451B1 (enExample)
JP (1) JP2005516030A (enExample)
KR (1) KR100919927B1 (enExample)
AT (1) ATE318813T1 (enExample)
AU (1) AU2002350753B2 (enExample)
CA (1) CA2470164A1 (enExample)
DE (1) DE60209537T2 (enExample)
DK (1) DK1462451T3 (enExample)
ES (2) ES2223209B1 (enExample)
HU (1) HUP0402536A3 (enExample)
MX (1) MXPA04005338A (enExample)
NO (1) NO326746B1 (enExample)
NZ (1) NZ533521A (enExample)
PL (1) PL370435A1 (enExample)
PT (1) PT1462451E (enExample)
WO (1) WO2003057692A1 (enExample)
ZA (1) ZA200404475B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
DE10161077A1 (de) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
DE102004021281A1 (de) * 2004-04-29 2005-11-24 Boehringer Ingelheim Vetmedica Gmbh Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin
DE102004030409A1 (de) * 2004-06-23 2006-01-26 Boehringer Ingelheim Vetmedica Gmbh Neue Verwendung von Meloxicam in der Veterinärmedizin
ITMI20041918A1 (it) 2004-10-11 2005-01-11 A M S A Anonima Materie Sintetiche Affini Spa Processo di purificazione di meloxicam
HU227359B1 (en) * 2004-12-18 2011-04-28 Egis Gyogyszergyar Nyilvanosan Mikodi Ruszvunytarsasag Process for producing meloxicam and meloxicam potassium salt of high purity
FR2889847B1 (fr) 2005-08-18 2007-10-05 Sanofi Aventis Sa Derives de 5-pyridazinyl-1-azabicyclo[3.2.1]octave, leur preparation en therapeutique.
SG166115A1 (en) * 2005-09-30 2010-11-29 Boehringer Ingelheim Vetmed Pharmaceutical preparation containing meloxicam
GB2443891B (en) * 2006-11-20 2009-04-08 Norbrook Lab Ltd Process for the purification of meloxicam
EP2244712B1 (en) * 2008-01-22 2015-08-05 Thar Pharmaceuticals Inc. In vivo studies of crystalline forms of meloxicam
EP2488145B1 (en) * 2009-10-12 2024-04-24 Boehringer Ingelheim Vetmedica GmbH Containers for compositions comprising meloxicam
SG183846A1 (en) 2010-03-03 2012-10-30 Boehringer Ingelheim Vetmed Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
CN103772378B (zh) * 2014-01-26 2016-02-24 悦康药业集团有限公司 一种美洛昔康化合物及其片剂
US20210322316A1 (en) * 2016-11-18 2021-10-21 Pacira Pharmaceuticals, Inc. Zinc meloxicam complex microparticles and anesthetic formulations and processes for making the same
EP3541815A4 (en) * 2016-11-18 2020-07-15 Pacira Pharmaceuticals, Inc. ZINC MELXICAM COMPLEX MICROPARTICLE MULTIVESICULAR LIPOSOME FORMULATIONS AND METHODS OF MAKING THE SAME
US20220184095A1 (en) 2019-04-22 2022-06-16 Mylan Specialty L.P. Meloxicam co-crystal compositions
AU2021375409A1 (en) 2020-11-06 2023-06-29 Mylan Laboratories Ltd Pharmaceutical composition comprising meloxicam
CN116421567B (zh) * 2023-04-27 2025-02-07 浙江萃泽医药科技有限公司 一种稳定冻干制剂及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2756113A1 (de) * 1977-12-16 1979-06-21 Thomae Gmbh Dr K Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US6355666B1 (en) * 2000-06-23 2002-03-12 Medinox, Inc. Protected forms of pharmacologically active agents and uses therefor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
논문 Eur.J.Pharm.Sci.(1996)*

Also Published As

Publication number Publication date
NZ533521A (en) 2005-07-29
DK1462451T3 (da) 2006-06-12
ES2223209B1 (es) 2005-10-01
JP2005516030A (ja) 2005-06-02
PL370435A1 (en) 2005-05-30
EP1462451B1 (en) 2006-03-01
PT1462451E (pt) 2006-07-31
EP1462451A1 (en) 2004-09-29
NO326746B1 (no) 2009-02-09
DE60209537D1 (de) 2006-04-27
WO2003057692A1 (es) 2003-07-17
CA2470164A1 (en) 2003-07-17
US6967248B2 (en) 2005-11-22
US20030109701A1 (en) 2003-06-12
MXPA04005338A (es) 2005-03-31
ATE318813T1 (de) 2006-03-15
DE60209537T2 (de) 2006-11-16
HUP0402536A2 (hu) 2005-04-28
ZA200404475B (en) 2005-06-07
NO20042936L (no) 2004-09-13
KR20040082380A (ko) 2004-09-24
AU2002350753B2 (en) 2008-05-08
AU2002350753A1 (en) 2003-07-24
ES2223209A1 (es) 2005-02-16
HUP0402536A3 (en) 2011-03-28
ES2259725T3 (es) 2006-10-16

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