KR100880828B1 - 펩타이드 정제 - Google Patents

펩타이드 정제 Download PDF

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Publication number
KR100880828B1
KR100880828B1 KR1020047010363A KR20047010363A KR100880828B1 KR 100880828 B1 KR100880828 B1 KR 100880828B1 KR 1020047010363 A KR1020047010363 A KR 1020047010363A KR 20047010363 A KR20047010363 A KR 20047010363A KR 100880828 B1 KR100880828 B1 KR 100880828B1
Authority
KR
South Korea
Prior art keywords
solvent mixture
nona
solvent
precipitated
decapeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020047010363A
Other languages
English (en)
Korean (ko)
Other versions
KR20040090966A (ko
Inventor
라스무센욘에이취.
라스무센팔레에이취.
Original Assignee
폴리펩타이드 라보라토리즈 에이/에스
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 폴리펩타이드 라보라토리즈 에이/에스 filed Critical 폴리펩타이드 라보라토리즈 에이/에스
Publication of KR20040090966A publication Critical patent/KR20040090966A/ko
Application granted granted Critical
Publication of KR100880828B1 publication Critical patent/KR100880828B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020047010363A 2001-12-29 2002-12-23 펩타이드 정제 Expired - Fee Related KR100880828B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0104462-7 2001-12-29
SE0104462A SE0104462D0 (sv) 2001-12-29 2001-12-29 Peptide purifcation (Peptidrening)
PCT/IB2002/005581 WO2003055900A1 (en) 2001-12-29 2002-12-23 Peptide purification

Publications (2)

Publication Number Publication Date
KR20040090966A KR20040090966A (ko) 2004-10-27
KR100880828B1 true KR100880828B1 (ko) 2009-01-30

Family

ID=20286556

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020047010363A Expired - Fee Related KR100880828B1 (ko) 2001-12-29 2002-12-23 펩타이드 정제

Country Status (18)

Country Link
US (1) US7057014B2 (enExample)
EP (1) EP1468009B1 (enExample)
JP (1) JP4378173B2 (enExample)
KR (1) KR100880828B1 (enExample)
CN (1) CN1272341C (enExample)
AT (1) ATE449784T1 (enExample)
AU (1) AU2002347550B2 (enExample)
CA (1) CA2471717C (enExample)
DE (1) DE60234535D1 (enExample)
DK (1) DK1468009T3 (enExample)
ES (1) ES2350880T3 (enExample)
IL (2) IL162789A0 (enExample)
NO (1) NO329024B1 (enExample)
NZ (1) NZ534151A (enExample)
RU (1) RU2303040C2 (enExample)
SE (1) SE0104462D0 (enExample)
WO (1) WO2003055900A1 (enExample)
ZA (1) ZA200405135B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1359722A1 (en) * 2002-03-27 2003-11-05 BRITISH TELECOMMUNICATIONS public limited company Data streaming system and method
EP1845973B1 (en) 2005-01-21 2015-08-12 Astex Therapeutics Limited Pharmaceutical compounds
JP5528806B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
JP5528807B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
US9051349B2 (en) 2007-11-21 2015-06-09 Alba Therapeutics Corporation Larazotide acetate compositions
EP2062909A1 (en) * 2007-11-21 2009-05-27 SOLVAY (Société Anonyme) Peptide production and purification process
CN102027005A (zh) * 2008-05-15 2011-04-20 诺沃-诺迪斯克有限公司 通过固相合成制备的肽的纯化
CN102482326A (zh) * 2009-04-10 2012-05-30 科登制药科罗拉多公司 分离治疗用肽的方法
AU2013360335B2 (en) 2012-12-13 2017-12-07 Immunomedics, Inc. Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
ES2819573T3 (es) 2012-12-13 2021-04-16 Immunomedics Inc Método para producir inmunoconjugados de anticuerpo-SN-38 con un enlazador CL2A
US9931417B2 (en) 2012-12-13 2018-04-03 Immunomedics, Inc. Antibody-SN-38 immunoconjugates with a CL2A linker
EP3024460B1 (en) * 2013-07-23 2020-07-22 Immunomedics, Inc. Method for producing antibody-sn-38 immunoconjugates with a cl2a linker
WO2017189279A1 (en) 2016-04-27 2017-11-02 Immunomedics, Inc. Efficacy of anti-trop-2-sn-38 antibody drug conjugates for therapy of tumors relapsed/refractory to checkpoint inhibitors
EP3600283A4 (en) 2017-03-27 2020-12-16 Immunomedics, Inc. TREATMENT OF TROP-2 EXPRESSIVE TRIPLE NEGATIVE BREAST CANCER WITH SACITUZUMAB GOVITECAN AND A RAD51 INHIBITOR
US10799597B2 (en) 2017-04-03 2020-10-13 Immunomedics, Inc. Subcutaneous administration of antibody-drug conjugates for cancer therapy
CN113952944B (zh) * 2021-12-23 2022-03-29 浙江湃肽生物有限公司深圳分公司 一种纯化九肽-1的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000018423A1 (en) 1998-09-30 2000-04-06 Laboratoire Theramex Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of lh-rh analogues

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8317697D0 (en) * 1983-06-29 1983-08-03 Shell Int Research Dissolution of peptides in non-aqueous and mixed non-aqueous/aqueous solvents
DE4001238A1 (de) * 1990-01-18 1991-07-25 Basf Ag Verfahren zur anreicherung bzw. reinigung von biomolekuelen
DE19544212A1 (de) * 1995-11-28 1997-06-05 Asta Medica Ag Neue LH-RH-Antagonisten mit verbesserter Wirkung
DE19813849A1 (de) * 1998-03-27 1999-09-30 Degussa Verfahren zur einstufigen Umsalzung und Aufreinigung von Oligopeptiden
DE19911771B4 (de) * 1999-03-17 2006-03-30 Zentaris Gmbh LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000018423A1 (en) 1998-09-30 2000-04-06 Laboratoire Theramex Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of lh-rh analogues

Also Published As

Publication number Publication date
DE60234535D1 (de) 2010-01-07
IL162789A0 (en) 2005-11-20
ATE449784T1 (de) 2009-12-15
JP4378173B2 (ja) 2009-12-02
US20060014694A1 (en) 2006-01-19
RU2303040C2 (ru) 2007-07-20
JP2005515217A (ja) 2005-05-26
CA2471717A1 (en) 2003-07-10
DK1468009T3 (da) 2010-04-06
RU2004119965A (ru) 2006-01-10
CN1625561A (zh) 2005-06-08
AU2002347550A1 (en) 2003-07-15
NO20043046L (no) 2004-08-30
EP1468009A1 (en) 2004-10-20
SE0104462D0 (sv) 2001-12-29
CA2471717C (en) 2013-06-18
CN1272341C (zh) 2006-08-30
ES2350880T3 (es) 2011-01-27
EP1468009B1 (en) 2009-11-25
AU2002347550B2 (en) 2008-01-03
IL162789A (en) 2010-04-29
ZA200405135B (en) 2005-08-31
HK1076112A1 (en) 2006-01-06
US7057014B2 (en) 2006-06-06
WO2003055900A1 (en) 2003-07-10
KR20040090966A (ko) 2004-10-27
NO329024B1 (no) 2010-08-02
NZ534151A (en) 2007-05-31

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