AU2002347550B2 - Peptide purification - Google Patents

Peptide purification Download PDF

Info

Publication number
AU2002347550B2
AU2002347550B2 AU2002347550A AU2002347550A AU2002347550B2 AU 2002347550 B2 AU2002347550 B2 AU 2002347550B2 AU 2002347550 A AU2002347550 A AU 2002347550A AU 2002347550 A AU2002347550 A AU 2002347550A AU 2002347550 B2 AU2002347550 B2 AU 2002347550B2
Authority
AU
Australia
Prior art keywords
sub
solvent mixture
solvent
precipitation
nona
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002347550A
Other languages
English (en)
Other versions
AU2002347550A1 (en
Inventor
Jon H. Rasmussen
Palle H Rasmussen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Polypeptide Laboratories AS
Original Assignee
Polypeptide Laboratories AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polypeptide Laboratories AS filed Critical Polypeptide Laboratories AS
Publication of AU2002347550A1 publication Critical patent/AU2002347550A1/en
Application granted granted Critical
Publication of AU2002347550B2 publication Critical patent/AU2002347550B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2002347550A 2001-12-29 2002-12-23 Peptide purification Ceased AU2002347550B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0104462A SE0104462D0 (sv) 2001-12-29 2001-12-29 Peptide purifcation (Peptidrening)
SE0104462-7 2001-12-29
PCT/IB2002/005581 WO2003055900A1 (en) 2001-12-29 2002-12-23 Peptide purification

Publications (2)

Publication Number Publication Date
AU2002347550A1 AU2002347550A1 (en) 2003-07-15
AU2002347550B2 true AU2002347550B2 (en) 2008-01-03

Family

ID=20286556

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002347550A Ceased AU2002347550B2 (en) 2001-12-29 2002-12-23 Peptide purification

Country Status (18)

Country Link
US (1) US7057014B2 (enExample)
EP (1) EP1468009B1 (enExample)
JP (1) JP4378173B2 (enExample)
KR (1) KR100880828B1 (enExample)
CN (1) CN1272341C (enExample)
AT (1) ATE449784T1 (enExample)
AU (1) AU2002347550B2 (enExample)
CA (1) CA2471717C (enExample)
DE (1) DE60234535D1 (enExample)
DK (1) DK1468009T3 (enExample)
ES (1) ES2350880T3 (enExample)
IL (2) IL162789A0 (enExample)
NO (1) NO329024B1 (enExample)
NZ (1) NZ534151A (enExample)
RU (1) RU2303040C2 (enExample)
SE (1) SE0104462D0 (enExample)
WO (1) WO2003055900A1 (enExample)
ZA (1) ZA200405135B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1359722A1 (en) * 2002-03-27 2003-11-05 BRITISH TELECOMMUNICATIONS public limited company Data streaming system and method
WO2006077428A1 (en) 2005-01-21 2006-07-27 Astex Therapeutics Limited Pharmaceutical compounds
JP5528807B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
EP2062909A1 (en) * 2007-11-21 2009-05-27 SOLVAY (Société Anonyme) Peptide production and purification process
US9051349B2 (en) 2007-11-21 2015-06-09 Alba Therapeutics Corporation Larazotide acetate compositions
US20120149868A1 (en) * 2008-05-15 2012-06-14 Novo Nordisk A/S Purification of peptides prepared by solid phase synthesis
CN102482326A (zh) * 2009-04-10 2012-05-30 科登制药科罗拉多公司 分离治疗用肽的方法
JP6366111B2 (ja) 2012-12-13 2018-08-01 イミューノメディクス、インコーポレイテッドＩｍｍｕｎｏｍｅｄｉｃｓ， Ｉｎｃ． 有効性の改善および毒性の減少のための、抗体およびｓｎ−３８からなるイムノコンジュゲートの投薬
WO2015012904A2 (en) 2012-12-13 2015-01-29 Immunomedics, Inc. Antibody-sn-38 immunoconjugates with a cl2a linker
US9931417B2 (en) 2012-12-13 2018-04-03 Immunomedics, Inc. Antibody-SN-38 immunoconjugates with a CL2A linker
EP3024460B1 (en) * 2013-07-23 2020-07-22 Immunomedics, Inc. Method for producing antibody-sn-38 immunoconjugates with a cl2a linker
CA3016917A1 (en) 2016-04-27 2017-11-02 Immunomedics, Inc. Efficacy of anti-trop-2-sn-38 antibody drug conjugates for therapy of tumors relapsed/refractory to checkpoint inhibitors
JP2020512314A (ja) 2017-03-27 2020-04-23 イミューノメディクス、インコーポレイテッドＩｍｍｕｎｏｍｅｄｉｃｓ， Ｉｎｃ． サシツズマブゴビテカンとＲＡＤ５１阻害剤を用いたＴｒｏｐ−２発現トリプルネガティブ乳癌の治療
CN110352201A (zh) 2017-04-03 2019-10-18 免疫医疗公司 用于癌症疗法的抗体药物缀合物的皮下施用
CN113952944B (zh) * 2021-12-23 2022-03-29 浙江湃肽生物有限公司深圳分公司 一种纯化九肽-1的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8317697D0 (en) * 1983-06-29 1983-08-03 Shell Int Research Dissolution of peptides in non-aqueous and mixed non-aqueous/aqueous solvents
DE4001238A1 (de) * 1990-01-18 1991-07-25 Basf Ag Verfahren zur anreicherung bzw. reinigung von biomolekuelen
DE19544212A1 (de) * 1995-11-28 1997-06-05 Asta Medica Ag Neue LH-RH-Antagonisten mit verbesserter Wirkung
DE19813849A1 (de) * 1998-03-27 1999-09-30 Degussa Verfahren zur einstufigen Umsalzung und Aufreinigung von Oligopeptiden
EP0998940A1 (en) 1998-09-30 2000-05-10 Laboratoire Theramex Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of LH-RH analogues
DE19911771B4 (de) * 1999-03-17 2006-03-30 Zentaris Gmbh LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung

Also Published As

Publication number Publication date
SE0104462D0 (sv) 2001-12-29
EP1468009B1 (en) 2009-11-25
DK1468009T3 (da) 2010-04-06
RU2004119965A (ru) 2006-01-10
CA2471717A1 (en) 2003-07-10
CN1625561A (zh) 2005-06-08
DE60234535D1 (de) 2010-01-07
AU2002347550A1 (en) 2003-07-15
US20060014694A1 (en) 2006-01-19
IL162789A (en) 2010-04-29
JP2005515217A (ja) 2005-05-26
KR100880828B1 (ko) 2009-01-30
KR20040090966A (ko) 2004-10-27
JP4378173B2 (ja) 2009-12-02
CA2471717C (en) 2013-06-18
US7057014B2 (en) 2006-06-06
CN1272341C (zh) 2006-08-30
NO329024B1 (no) 2010-08-02
WO2003055900A1 (en) 2003-07-10
NZ534151A (en) 2007-05-31
ATE449784T1 (de) 2009-12-15
HK1076112A1 (en) 2006-01-06
ES2350880T3 (es) 2011-01-27
IL162789A0 (en) 2005-11-20
ZA200405135B (en) 2005-08-31
EP1468009A1 (en) 2004-10-20
RU2303040C2 (ru) 2007-07-20
NO20043046L (no) 2004-08-30

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired