KR100844191B1 - 이식 대기중인 기관의 저장 및 관류를 위한 용액 - Google Patents

이식 대기중인 기관의 저장 및 관류를 위한 용액 Download PDF

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Publication number
KR100844191B1
KR100844191B1 KR1020037016372A KR20037016372A KR100844191B1 KR 100844191 B1 KR100844191 B1 KR 100844191B1 KR 1020037016372 A KR1020037016372 A KR 1020037016372A KR 20037016372 A KR20037016372 A KR 20037016372A KR 100844191 B1 KR100844191 B1 KR 100844191B1
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South Korea
Prior art keywords
carnitine
solution
acid
physiologically acceptable
alkanoyl
Prior art date
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Expired - Fee Related
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KR1020037016372A
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English (en)
Korean (ko)
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KR20040010712A (ko
Inventor
알두이노 알두이니
토마소 아우릴레
Original Assignee
시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이.
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Application filed by 시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이. filed Critical 시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이.
Publication of KR20040010712A publication Critical patent/KR20040010712A/ko
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Publication of KR100844191B1 publication Critical patent/KR100844191B1/ko
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020037016372A 2001-06-14 2002-06-13 이식 대기중인 기관의 저장 및 관류를 위한 용액 Expired - Fee Related KR100844191B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT2001RM000337A ITRM20010337A1 (it) 2001-06-14 2001-06-14 Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.
ITRM2001A000337 2001-06-14
PCT/IT2002/000391 WO2002102149A1 (en) 2001-06-14 2002-06-13 Solution for the storage and perfusion of organs awaiting transplantation

Publications (2)

Publication Number Publication Date
KR20040010712A KR20040010712A (ko) 2004-01-31
KR100844191B1 true KR100844191B1 (ko) 2008-07-04

Family

ID=11455594

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020037016372A Expired - Fee Related KR100844191B1 (ko) 2001-06-14 2002-06-13 이식 대기중인 기관의 저장 및 관류를 위한 용액

Country Status (15)

Country Link
US (3) US7422844B2 (OSRAM)
EP (1) EP1401270B1 (OSRAM)
JP (1) JP4268036B2 (OSRAM)
KR (1) KR100844191B1 (OSRAM)
AT (1) ATE336166T1 (OSRAM)
CA (1) CA2450623C (OSRAM)
CY (1) CY1106202T1 (OSRAM)
DE (1) DE60213990T2 (OSRAM)
DK (1) DK1401270T3 (OSRAM)
ES (1) ES2271290T3 (OSRAM)
IT (1) ITRM20010337A1 (OSRAM)
MX (1) MXPA03011461A (OSRAM)
PL (1) PL206312B1 (OSRAM)
PT (1) PT1401270E (OSRAM)
WO (1) WO2002102149A1 (OSRAM)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20010337A1 (it) * 2001-06-14 2002-12-16 Sigma Tau Ind Farmaceuti Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.
JP2005095152A (ja) * 2003-08-29 2005-04-14 Japan Tissue Engineering:Kk 培養組織の保存方法
WO2006026304A1 (en) * 2004-08-25 2006-03-09 Ivax Corporation Cardioprotective formulations and uses thereof
TWI388318B (zh) * 2005-03-10 2013-03-11 Sigma Tau Ind Farmaceuti 具有改良之生物相容性的含有肉毒鹼之腹膜透析溶液
JP2006347935A (ja) * 2005-06-15 2006-12-28 Masanori Ogata 炎症性サイトカインの産生が関与する疾患の予防及び／又は治療のための医薬
GB0612877D0 (en) * 2006-06-29 2006-08-09 Univ Edinburgh Organ preservation solution
CN105746492A (zh) * 2007-02-17 2016-07-13 哈佛学院董事会 用于进行组织保存的组合物以及方法
WO2009105164A2 (en) 2008-02-15 2009-08-27 President And Fellows Of Harvard College Blood substitute solution
WO2010147111A1 (ja) * 2009-06-15 2010-12-23 トヨタ自動車株式会社 無細胞タンパク質合成溶液、無細胞タンパク質合成キット及びタンパク質合成方法
RU2707532C1 (ru) * 2018-10-11 2019-11-27 Российская Федерация, от имени которой выступает ФОНД ПЕРСПЕКТИВНЫХ ИССЛЕДОВАНИЙ Способ повышения безопасности и эффективности хранения и транспортировки трансплантируемого органа под давлением консервирующей газовой смеси и устройство на его основе
CN109511650B (zh) * 2018-11-21 2021-06-15 嘉兴莱普晟医疗科技有限公司 一种可以扩大供肝来源的常温机械灌注液
IT201900007446A1 (it) * 2019-05-29 2020-11-29 Giuseppe Castellano Composizione comprendente citrato e carnitina in grado di attivare la produzione della proteina klotho
WO2021183653A1 (en) * 2020-03-10 2021-09-16 University Of Florida Research Foundation, Incorporated Compositions for extending viable preservation and shelf-life of organs and tissues

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000030637A1 (en) 1998-11-26 2000-06-02 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of fumarate salt of l-carnitine or its alkanoyl derivatives in ischaemia

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5498427A (en) 1990-11-20 1996-03-12 Pasteur Merieux Serums Et Vaccines Solutions for the perfusion, preservation and reperfusion of organs
IT1261695B (it) * 1993-06-02 1996-05-29 Sigma Tau Ind Farmaceuti Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono.
CA2207324A1 (en) * 1994-12-12 1996-06-20 Richard M. Raymond Organ transplant solutions and method for transplanting an organ
US5707971A (en) * 1995-06-07 1998-01-13 Life Resuscitation Technologies, Inc. Modulation of glycolytic ATP production
US5834178C1 (en) * 1997-07-09 2002-04-23 Univ Wayne State Flush-storage solution for donor organs
JP4638106B2 (ja) 1999-10-11 2011-02-23 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ 医薬的使用のための溶液中における浸透圧剤としての、ｌ−カルニチンおよびそのアルカノイル誘導体の使用
ITRM20010337A1 (it) 2001-06-14 2002-12-16 Sigma Tau Ind Farmaceuti Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000030637A1 (en) 1998-11-26 2000-06-02 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of fumarate salt of l-carnitine or its alkanoyl derivatives in ischaemia

Also Published As

Publication number Publication date
KR20040010712A (ko) 2004-01-31
DE60213990T2 (de) 2007-03-15
US20080199844A1 (en) 2008-08-21
DE60213990D1 (de) 2006-09-28
DK1401270T3 (da) 2006-12-27
ATE336166T1 (de) 2006-09-15
US20040156990A1 (en) 2004-08-12
CA2450623A1 (en) 2002-12-27
EP1401270A1 (en) 2004-03-31
US8007993B2 (en) 2011-08-30
PL367837A1 (en) 2005-03-07
US20080166695A1 (en) 2008-07-10
ES2271290T3 (es) 2007-04-16
EP1401270B1 (en) 2006-08-16
PT1401270E (pt) 2006-10-31
ITRM20010337A0 (it) 2001-06-14
US7989158B2 (en) 2011-08-02
MXPA03011461A (es) 2004-07-01
CA2450623C (en) 2011-05-10
ITRM20010337A1 (it) 2002-12-16
PL206312B1 (pl) 2010-07-30
CY1106202T1 (el) 2011-06-08
WO2002102149A1 (en) 2002-12-27
JP2004529205A (ja) 2004-09-24
JP4268036B2 (ja) 2009-05-27
US7422844B2 (en) 2008-09-09

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KR950015064B1 (ko) 기관 보존 및 저장에 적당한 조성물
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