KR100786654B1 - 신규 제제 - Google Patents

신규 제제 Download PDF

Info

Publication number
KR100786654B1
KR100786654B1 KR1020007000205A KR20007000205A KR100786654B1 KR 100786654 B1 KR100786654 B1 KR 100786654B1 KR 1020007000205 A KR1020007000205 A KR 1020007000205A KR 20007000205 A KR20007000205 A KR 20007000205A KR 100786654 B1 KR100786654 B1 KR 100786654B1
Authority
KR
South Korea
Prior art keywords
pharmaceutical composition
composition according
formula
glass forming
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
KR1020007000205A
Other languages
English (en)
Korean (ko)
Other versions
KR20010021647A (ko
Inventor
조안 브로드헤드
Original Assignee
아스트라제네카 유케이 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20407718&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR100786654(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 아스트라제네카 유케이 리미티드 filed Critical 아스트라제네카 유케이 리미티드
Publication of KR20010021647A publication Critical patent/KR20010021647A/ko
Application granted granted Critical
Publication of KR100786654B1 publication Critical patent/KR100786654B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020007000205A 1997-07-11 1998-06-29 신규 제제 Expired - Lifetime KR100786654B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9702680-1 1997-07-11
SE9702680A SE9702680D0 (sv) 1997-07-11 1997-07-11 New formulation
PCT/SE1998/001287 WO1999002542A1 (en) 1997-07-11 1998-06-29 New formulation

Publications (2)

Publication Number Publication Date
KR20010021647A KR20010021647A (ko) 2001-03-15
KR100786654B1 true KR100786654B1 (ko) 2007-12-21

Family

ID=20407718

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007000205A Expired - Lifetime KR100786654B1 (ko) 1997-07-11 1998-06-29 신규 제제

Country Status (35)

Country Link
US (1) US6130208A (https=)
EP (1) EP1000079B1 (https=)
JP (1) JP4950380B2 (https=)
KR (1) KR100786654B1 (https=)
CN (2) CN1864696A (https=)
AR (1) AR013157A1 (https=)
AT (1) ATE340801T1 (https=)
AU (1) AU8362598A (https=)
BR (1) BR9810703A (https=)
CA (1) CA2295628C (https=)
CY (1) CY1105805T1 (https=)
CZ (1) CZ298110B6 (https=)
DE (1) DE69836023T2 (https=)
DK (1) DK1000079T3 (https=)
EE (1) EE04119B1 (https=)
ES (1) ES2273425T3 (https=)
HU (1) HU226489B1 (https=)
ID (1) ID24716A (https=)
IL (2) IL133868A0 (https=)
IS (1) IS2439B (https=)
MY (1) MY116421A (https=)
NO (1) NO329918B1 (https=)
NZ (1) NZ502073A (https=)
PL (1) PL192768B1 (https=)
PT (1) PT1000079E (https=)
RU (1) RU2216330C2 (https=)
SA (1) SA98190328B1 (https=)
SE (1) SE9702680D0 (https=)
SI (1) SI1000079T1 (https=)
SK (1) SK285766B6 (https=)
TR (1) TR200000006T2 (https=)
TW (1) TW585764B (https=)
UA (1) UA65576C2 (https=)
WO (1) WO1999002542A1 (https=)
ZA (1) ZA985669B (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7879567B2 (en) * 2004-10-05 2011-02-01 Asahi Kasei Pharma Corporation Method for stabilizing coenzyme and composition therefor
WO2009140092A1 (en) 2008-05-13 2009-11-19 The Medicines Company Maintenance of platelet inhibition during antiplatelet therapy
US20130303477A1 (en) 2008-05-13 2013-11-14 The Medicines Company Maintenance of Platelet Inhibition During Antiplatelet Therapy
US20120141468A1 (en) * 2008-05-13 2012-06-07 Lisa Ruderman Chen Maintenance of platelet inhibition during antiplatelet therapy
US8759316B2 (en) 2008-05-13 2014-06-24 The Medicines Company Maintenance of platelet inhibition during antiplatelet therapy
US9427448B2 (en) 2009-11-11 2016-08-30 The Medicines Company Methods of treating, reducing the incidence of, and/or preventing ischemic events
ES2470329T3 (es) 2009-08-28 2014-06-23 Daiichi Sankyo Company, Limited Derivado del ácido 3-(biariloxi) priopi�nico
PT2498731T (pt) 2009-11-11 2020-02-21 Chiesi Farm Spa Métodos de tratamento ou prevenção de uma trombose de endoprótese
US10376532B2 (en) 2009-11-11 2019-08-13 Chiesi Farmaceutici, S.P.A. Methods of treating, reducing the incidence of, and/or preventing ischemic events
RU2606845C2 (ru) * 2010-12-10 2017-01-10 СИГМАФАРМ ЛЭБОРЭТОРИЗ, ЭлЭлСи Высокостабильные композиции перорально активных аналогов нуклеотидов или перорально активных пролекарств аналогов нуклеотидов
AU2012214396B2 (en) 2011-02-09 2017-04-27 Chiesi Farmaceutici S.P.A. Methods for treating pulmonary hypertension
DK2744424T3 (en) 2011-08-17 2018-01-22 Samuel Shiber Adaptively rotating catheter to open clogged vessels in the body
BR112015022070B1 (pt) 2013-03-09 2022-01-18 Chiesi Farmaceutici S.P.A. Uso de cangrelor
CN103772461A (zh) * 2014-01-06 2014-05-07 南京正科制药有限公司 一种坎格雷洛晶型ⅰ
EP3244900A4 (en) 2015-01-14 2018-05-30 Chiesi Farmaceutici S.p.A. Pharmaceutical formulations comprising high purity cangrelor and methods for preparing and using the same
US11260071B2 (en) 2017-06-23 2022-03-01 Chiesi Farmaceutici S.P.A. Method of preventing of systemic-to-pulmonary-artery shunt thrombosis
TWI857957B (zh) 2018-06-19 2024-10-11 德商Ｕｃｂ製藥有限公司 吡啶基及吡基-（氮）吲哚磺醯胺

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5874696A (ja) * 1981-10-30 1983-05-06 株式会社　ヤトロン アデノシン三リン酸の安定化方法
WO1994018216A1 (en) * 1993-02-10 1994-08-18 Astra Pharmaceuticals Limited N-alkyl-2-substituted atp analogues

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5637967B2 (https=) * 1973-05-17 1981-09-03
JPS5874966A (ja) * 1981-10-28 1983-05-06 Mikuni Jukogyo Kk 高圧往復動機の軸封装置
AU659645B2 (en) * 1991-06-26 1995-05-25 Inhale Therapeutic Systems Storage of materials
AU3095092A (en) * 1991-12-09 1993-07-19 Asahi Kasei Kogyo Kabushiki Kaisha Stabilized parathyroid hormone composition
ZA949715B (en) * 1993-12-14 1996-06-06 Lilly Co Eli Aqueous solution inclusion complexes of benzothiophene compounds with water soluble cyclodextrins and pharmaceutical formulations and methods thereof
DE4405426A1 (de) * 1994-02-21 1995-08-24 Boehringer Mannheim Gmbh Pharmazeutisches Präparat enthaltend Plasminogenaktivator (t-PA) oder dessen Derivate
CA2223921A1 (en) * 1995-06-07 1996-12-19 Francis C. Szoka, Jr. Stabilization of polynucleotide complexes
FR2740686B1 (fr) * 1995-11-03 1998-01-16 Sanofi Sa Formulation pharmaceutique lyophilisee stable
ID21635A (id) * 1996-12-20 1999-07-08 Astra Pharma Prod Komposisi farmasi untuk pengeringan beku

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5874696A (ja) * 1981-10-30 1983-05-06 株式会社　ヤトロン アデノシン三リン酸の安定化方法
WO1994018216A1 (en) * 1993-02-10 1994-08-18 Astra Pharmaceuticals Limited N-alkyl-2-substituted atp analogues

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
일본공개특허공보 소58-74696호

Also Published As

Publication number Publication date
AR013157A1 (es) 2000-12-13
SI1000079T1 (sl) 2007-08-31
CN1864696A (zh) 2006-11-22
PL192768B1 (pl) 2006-12-29
WO1999002542A1 (en) 1999-01-21
CY1105805T1 (el) 2011-02-02
IL133868A (en) 2010-05-17
MY116421A (en) 2004-01-31
EP1000079B1 (en) 2006-09-27
US6130208A (en) 2000-10-10
DE69836023D1 (de) 2006-11-09
BR9810703A (pt) 2000-08-08
DK1000079T3 (da) 2006-11-20
IS2439B (is) 2008-11-15
CA2295628A1 (en) 1999-01-21
SE9702680D0 (sv) 1997-07-11
NZ502073A (en) 2001-09-28
KR20010021647A (ko) 2001-03-15
PL337970A1 (en) 2000-09-11
ID24716A (id) 2000-08-03
ZA985669B (en) 1999-01-11
EE04119B1 (et) 2003-08-15
SA98190328B1 (ar) 2006-08-15
UA65576C2 (uk) 2004-04-15
SK183699A3 (en) 2000-07-11
HK1026429A1 (en) 2000-12-15
SK285766B6 (sk) 2007-07-06
ATE340801T1 (de) 2006-10-15
NO20000123D0 (no) 2000-01-10
IS5331A (is) 1999-12-30
TW585764B (en) 2004-05-01
JP4950380B2 (ja) 2012-06-13
PT1000079E (pt) 2006-12-29
CZ200083A3 (cs) 2000-06-14
EP1000079A1 (en) 2000-05-17
DE69836023T2 (de) 2007-04-12
ES2273425T3 (es) 2007-05-01
HUP0002622A3 (en) 2002-04-29
RU2216330C2 (ru) 2003-11-20
AU8362598A (en) 1999-02-08
HU226489B1 (en) 2009-03-02
EE200000022A (et) 2000-10-16
CA2295628C (en) 2008-07-29
NO20000123L (no) 2000-03-03
JP2001509512A (ja) 2001-07-24
NO329918B1 (no) 2011-01-24
TR200000006T2 (tr) 2000-07-21
HUP0002622A2 (hu) 2001-05-28
IL133868A0 (en) 2001-04-30
CZ298110B6 (cs) 2007-06-27
CN1263533A (zh) 2000-08-16

Similar Documents

Publication Publication Date Title
KR100786654B1 (ko) 신규 제제
EP1007094B1 (en) Pharmaceutical compositions comprising a nucleotide analogue suitable for freeze drying
AU2003257524B2 (en) New formulation
HK1026429B (en) New formulation
MXPA00000100A (en) New formulation
HK1026366B (en) Pharmaceutical compositions comprising a nucleotide analogue suitable for freeze drying
MXPA99005664A (en) Pharmaceutical compositions for freeze drying

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E601 Decision to refuse application
PE0601 Decision on rejection of patent

St.27 status event code: N-2-6-B10-B15-exm-PE0601

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

N231 Notification of change of applicant
PN2301 Change of applicant

St.27 status event code: A-3-3-R10-R13-asn-PN2301

St.27 status event code: A-3-3-R10-R11-asn-PN2301

R18-X000 Changes to party contact information recorded

St.27 status event code: A-3-3-R10-R18-oth-X000

J201 Request for trial against refusal decision
PJ0201 Trial against decision of rejection

St.27 status event code: A-3-3-V10-V11-apl-PJ0201

J301 Trial decision

Free format text: TRIAL NUMBER: 2006101000180; TRIAL DECISION FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 20060111

Effective date: 20070918

PJ1301 Trial decision

St.27 status event code: A-3-3-V10-V15-crt-PJ1301

Decision date: 20070918

Appeal event data comment text: Appeal Kind Category : Appeal against decision to decline refusal, Appeal Ground Text : 2000 7000205

Appeal request date: 20060111

Appellate body name: Patent Examination Board

Decision authority category: Office appeal board

Decision identifier: 2006101000180

PS0901 Examination by remand of revocation

St.27 status event code: A-6-3-E10-E12-rex-PS0901

S901 Examination by remand of revocation
GRNO Decision to grant (after opposition)
PS0701 Decision of registration after remand of revocation

St.27 status event code: A-3-4-F10-F13-rex-PS0701

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

FPAY Annual fee payment

Payment date: 20121122

Year of fee payment: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

FPAY Annual fee payment

Payment date: 20131119

Year of fee payment: 7

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 7

FPAY Annual fee payment

Payment date: 20141124

Year of fee payment: 8

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 8

FPAY Annual fee payment

Payment date: 20151118

Year of fee payment: 9

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 9

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

FPAY Annual fee payment

Payment date: 20161123

Year of fee payment: 10

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 10

P22-X000 Classification modified

St.27 status event code: A-4-4-P10-P22-nap-X000

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 11

EXPY Expiration of term
PC1801 Expiration of term

St.27 status event code: N-4-6-H10-H14-oth-PC1801

Not in force date: 20180630

Ip right cessation event data comment text: Termination Category : EXPIRATION_OF_DURATION