KR100757630B1 - 신규한 추출 및 단리 방법으로 수득되는 세균성 캡슐형 다당류 - Google Patents

신규한 추출 및 단리 방법으로 수득되는 세균성 캡슐형 다당류 Download PDF

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KR100757630B1
KR100757630B1 KR1020067013976A KR20067013976A KR100757630B1 KR 100757630 B1 KR100757630 B1 KR 100757630B1 KR 1020067013976 A KR1020067013976 A KR 1020067013976A KR 20067013976 A KR20067013976 A KR 20067013976A KR 100757630 B1 KR100757630 B1 KR 100757630B1
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cps
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polysaccharides
polysaccharide
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KR20060086978A (ko
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프랜시스 미숑
밀란 블레이크
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박스터 헬쓰케어 에스.에이.
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
KR1020067013976A 1997-12-23 1998-12-23 신규한 추출 및 단리 방법으로 수득되는 세균성 캡슐형 다당류 Expired - Fee Related KR100757630B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6860897P 1997-12-23 1997-12-23
US60/068,608 1997-12-23
PCT/US1998/027375 WO1999032653A1 (en) 1997-12-23 1998-12-23 Procedures for the extraction and isolation of bacterial capsular polysaccharides for use as vaccines or linked to proteins as conjugates vaccines

Related Parent Applications (1)

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KR1020007006995A Division KR100641490B1 (ko) 1997-12-23 1998-12-23 백신용도이거나 결합백신으로서 단백질에 결합되는 세균성 캡슐형 다당류의 추출 및 단리방법

Publications (2)

Publication Number Publication Date
KR20060086978A KR20060086978A (ko) 2006-08-01
KR100757630B1 true KR100757630B1 (ko) 2007-09-10

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ID=22083630

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020067013976A Expired - Fee Related KR100757630B1 (ko) 1997-12-23 1998-12-23 신규한 추출 및 단리 방법으로 수득되는 세균성 캡슐형 다당류
KR1020007006995A Expired - Lifetime KR100641490B1 (ko) 1997-12-23 1998-12-23 백신용도이거나 결합백신으로서 단백질에 결합되는 세균성 캡슐형 다당류의 추출 및 단리방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020007006995A Expired - Lifetime KR100641490B1 (ko) 1997-12-23 1998-12-23 백신용도이거나 결합백신으로서 단백질에 결합되는 세균성 캡슐형 다당류의 추출 및 단리방법

Country Status (14)

Country Link
US (1) US6248570B1 (https=)
EP (3) EP2226336B1 (https=)
JP (2) JP4435413B2 (https=)
KR (2) KR100757630B1 (https=)
AT (1) ATE468403T2 (https=)
AU (1) AU754256C (https=)
CA (1) CA2316975C (https=)
CZ (1) CZ302615B6 (https=)
DE (1) DE69841676D1 (https=)
DK (1) DK1051506T4 (https=)
ES (2) ES2346022T3 (https=)
HU (1) HUP0100623A3 (https=)
NO (1) NO331100B1 (https=)
WO (1) WO1999032653A1 (https=)

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US7816514B2 (en) 2001-02-16 2010-10-19 Cargill, Incorporated Glucosamine and method of making glucosamine from microbial biomass
US20020115639A1 (en) * 2001-02-16 2002-08-22 Weiyu Fan Glucosamine and method of making glucosamine from microbial blomass
US7923437B2 (en) * 2001-02-16 2011-04-12 Cargill, Incorporated Water soluble β-glucan, glucosamine, and N-acetylglucosamine compositions and methods for making the same
US6693188B2 (en) 2001-08-08 2004-02-17 Cargill Incorporated N-acetyl-D-glucosamine and process for producing N-acetyl-D-glucosamine
US8222232B2 (en) * 2001-02-16 2012-07-17 Cargill, Incorporated Glucosamine and N-acetylglucosamine compositions and methods of making the same fungal biomass
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
ES2616180T3 (es) * 2002-03-26 2017-06-09 Glaxosmithkline Biologicals Sa Sacáridos modificados con estabilidad mejorada en agua para su uso como medicamento
WO2004011027A1 (en) * 2002-07-30 2004-02-05 Baxter International Inc. Chimeric multivalent polysaccharide conjugate vaccines
US20060058263A1 (en) * 2002-11-01 2006-03-16 Rogers Brent D Heat pasturized liquids containing glucosamine
US20060003965A1 (en) * 2002-11-01 2006-01-05 Fosdick Lawrence D N-acetyl-d-glucosamine (nag) supplemented food products and beverages
EP2172213B1 (en) 2003-01-30 2013-04-03 Novartis AG Injectable vaccines against multiple meningococcal serogroups
CA2530364C (en) * 2003-06-23 2014-03-18 Baxter International Inc. Vaccines against group y neisseria meningitidis and meningococcal combinations thereof
GB0406013D0 (en) * 2004-03-17 2004-04-21 Chiron Srl Analysis of saccharide vaccines without interference
US8652334B2 (en) 2004-08-12 2014-02-18 Lipoxen Technologies Limited Fractionation of charged polysaccharide
GB0502095D0 (en) * 2005-02-01 2005-03-09 Chiron Srl Conjugation of streptococcal capsular saccharides
GB0502096D0 (en) * 2005-02-01 2005-03-09 Chiron Srl Purification of streptococcal capsular polysaccharide
EP3311836A1 (en) 2005-04-08 2018-04-25 Wyeth LLC Multivalent pneumococcal polysaccharide-protein conjugate composition
AU2011253684B8 (en) * 2005-04-08 2013-07-11 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
CA2620416A1 (en) * 2005-08-24 2007-03-01 Novartis Vaccines And Diagnostics S.R.L. Zwitterionization of capsular saccharides
GB0522303D0 (en) 2005-11-01 2005-12-07 Chiron Srl Culture method
EP1976857A4 (en) * 2006-01-13 2011-08-03 Baxter Int PROCESS FOR CLEANING POLYSACCHARIDES
PL2004225T3 (pl) 2006-03-22 2012-09-28 Novartis Ag Schematy immunizacji koniugatami meningokokowymi
US10828361B2 (en) 2006-03-22 2020-11-10 Glaxosmithkline Biologicals Sa Regimens for immunisation with meningococcal conjugates
GB0605757D0 (en) * 2006-03-22 2006-05-03 Chiron Srl Separation of conjugated and unconjugated components
US8808707B1 (en) 2006-05-08 2014-08-19 Wyeth Llc Pneumococcal dosing regimen
EP1872791A1 (en) 2006-06-30 2008-01-02 Institut Pasteur Use of bacterial polysaccharides for biofilm inhibition
EP2409995A3 (en) 2007-02-28 2012-08-15 Lipoxen Technologies Limited Reduction of endotoxin in polysialic acids
SI2114421T1 (en) 2007-03-05 2018-04-30 Om Pharma A bacterial extract for respiratory disorders and a process for its preparation
CN101663327B (zh) * 2007-03-23 2014-05-07 惠氏公司 产生肺炎链球菌(streptococcus pneumoniae)荚膜多糖的缩短的纯化方法
GB0818453D0 (en) 2008-10-08 2008-11-12 Novartis Ag Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
JP5339243B2 (ja) * 2008-04-24 2013-11-13 株式会社微生物化学研究所 ストレプトコッカス・スイス感染症予防用ワクチン
WO2011005587A1 (en) * 2009-06-24 2011-01-13 University Of Dubuque Vaccine compositions and methods of use to protect against infectious disease
BR112013024322B1 (pt) * 2011-03-22 2020-04-22 Serum Inst India Ltd processo para preparação de polissacarídeos
US9400250B2 (en) 2013-09-30 2016-07-26 Han Sheng Biotech Co., Ltd. Method for analyzing mushrooms
MY186874A (en) * 2014-02-25 2021-08-26 Msd Wellcome Trust Hilleman Laboratories Pvt Ltd A novel downstream process for purifying polysaccharides
EP2942396A1 (en) 2014-05-07 2015-11-11 Novartis AG Polysaccharides produced by CPSC mutants
EP3034516A1 (en) * 2014-12-19 2016-06-22 Novartis AG Purification of streptococcal capsular polysaccharide
MY182282A (en) * 2015-05-04 2021-01-18 Pfizer Group b streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof
BE1025162B9 (fr) * 2016-12-06 2019-01-07 Glaxosmithkline Biologicals Sa Procede de purification pour les polysaccharides capsulaires
US11739356B2 (en) * 2017-05-05 2023-08-29 Serum Institute Of India Private Limited Method for removal of impurities from bacterial capsular polysaccharide based preparations
JP7111799B2 (ja) * 2017-07-05 2022-08-02 インベントプライズ リミテッド ライアビリティ カンパニー 溶菌酵素、接線流濾過、及びマルチモードクロマトグラフィを用いたワクチン生産のための多糖精製
CN111093650B (zh) 2017-09-07 2024-03-01 默沙东有限责任公司 肺炎球菌多糖及其在免疫原性多糖-载体蛋白缀合物中的用途
FR3078977B1 (fr) 2018-03-16 2023-03-17 Biomerieux Sa Procede d'extraction d'acides nucleiques
WO2022084852A1 (en) * 2020-10-22 2022-04-28 Pfizer Inc. Methods for purifying bacterial polysaccharides
CN117512031B (zh) * 2023-10-16 2024-06-25 江苏金迪克生物技术股份有限公司 一种肺炎球菌荚膜多糖的纯化方法

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US4413057A (en) 1980-04-14 1983-11-01 Merck & Co., Inc. Group B streptococcal capsular polysaccharides
EP0238739A1 (en) 1986-03-27 1987-09-30 Swiss Serum and Vaccine Institute Berne Klebsiella capsular polysaccharide vaccine
US5190746A (en) 1989-05-10 1993-03-02 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Plaque inhibiting oligosaccharide

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EP0238739A1 (en) 1986-03-27 1987-09-30 Swiss Serum and Vaccine Institute Berne Klebsiella capsular polysaccharide vaccine
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Also Published As

Publication number Publication date
DK1051506T3 (da) 2010-09-13
AU754256B2 (en) 2002-11-07
KR100641490B1 (ko) 2006-10-31
EP1051506B2 (en) 2019-08-21
AU754256C (en) 2004-05-20
CA2316975A1 (en) 1999-07-01
US6248570B1 (en) 2001-06-19
HK1147506A1 (en) 2011-08-12
JP2010011862A (ja) 2010-01-21
ES2346022T3 (es) 2010-10-07
JP4435413B2 (ja) 2010-03-17
WO1999032653A9 (en) 1999-10-28
KR20060086978A (ko) 2006-08-01
EP1051506B8 (en) 2010-09-01
KR20010033494A (ko) 2001-04-25
EP1051506A1 (en) 2000-11-15
HUP0100623A3 (en) 2003-11-28
CZ302615B6 (cs) 2011-08-03
NO331100B1 (no) 2011-10-03
EP2226336A1 (en) 2010-09-08
DE69841676D1 (de) 2010-07-01
ES2611464T3 (es) 2017-05-09
JP2001526902A (ja) 2001-12-25
EP2226336B1 (en) 2016-10-19
EP3118225A1 (en) 2017-01-18
DK1051506T4 (da) 2019-10-21
WO1999032653A1 (en) 1999-07-01
JP5144613B2 (ja) 2013-02-13
NO20003226D0 (no) 2000-06-21
HUP0100623A2 (hu) 2001-06-28
CZ20002373A3 (cs) 2000-12-13
AU2307199A (en) 1999-07-12
CA2316975C (en) 2009-03-24
EP1051506B1 (en) 2010-05-19
ATE468403T2 (de) 2010-06-15

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