DK1051506T4 - Fremgangsmåder til ekstraktion og isolering af bakterielle kapselpolysaccharider til anvendelse som vacciner eller bundet til proteiner som konjugatvacciner - Google Patents

Fremgangsmåder til ekstraktion og isolering af bakterielle kapselpolysaccharider til anvendelse som vacciner eller bundet til proteiner som konjugatvacciner Download PDF

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Publication number
DK1051506T4
DK1051506T4 DK98966468.5T DK98966468T DK1051506T4 DK 1051506 T4 DK1051506 T4 DK 1051506T4 DK 98966468 T DK98966468 T DK 98966468T DK 1051506 T4 DK1051506 T4 DK 1051506T4
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Denmark
Prior art keywords
vaccines
extraction
polyaccharides
cps
projects
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DK98966468.5T
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Danish (da)
English (en)
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DK1051506T3 (da
Inventor
Francis Michon
Milan Blake
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Pfizer Ireland Pharmaceuticals
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Publication of DK1051506T3 publication Critical patent/DK1051506T3/da
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
DK98966468.5T 1997-12-23 1998-12-23 Fremgangsmåder til ekstraktion og isolering af bakterielle kapselpolysaccharider til anvendelse som vacciner eller bundet til proteiner som konjugatvacciner DK1051506T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6860897P 1997-12-23 1997-12-23
PCT/US1998/027375 WO1999032653A1 (en) 1997-12-23 1998-12-23 Procedures for the extraction and isolation of bacterial capsular polysaccharides for use as vaccines or linked to proteins as conjugates vaccines

Publications (2)

Publication Number Publication Date
DK1051506T3 DK1051506T3 (da) 2010-09-13
DK1051506T4 true DK1051506T4 (da) 2019-10-21

Family

ID=22083630

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98966468.5T DK1051506T4 (da) 1997-12-23 1998-12-23 Fremgangsmåder til ekstraktion og isolering af bakterielle kapselpolysaccharider til anvendelse som vacciner eller bundet til proteiner som konjugatvacciner

Country Status (14)

Country Link
US (1) US6248570B1 (https=)
EP (3) EP2226336B1 (https=)
JP (2) JP4435413B2 (https=)
KR (2) KR100757630B1 (https=)
AT (1) ATE468403T2 (https=)
AU (1) AU754256C (https=)
CA (1) CA2316975C (https=)
CZ (1) CZ302615B6 (https=)
DE (1) DE69841676D1 (https=)
DK (1) DK1051506T4 (https=)
ES (2) ES2346022T3 (https=)
HU (1) HUP0100623A3 (https=)
NO (1) NO331100B1 (https=)
WO (1) WO1999032653A1 (https=)

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US6693188B2 (en) 2001-08-08 2004-02-17 Cargill Incorporated N-acetyl-D-glucosamine and process for producing N-acetyl-D-glucosamine
US8222232B2 (en) * 2001-02-16 2012-07-17 Cargill, Incorporated Glucosamine and N-acetylglucosamine compositions and methods of making the same fungal biomass
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GB0502095D0 (en) * 2005-02-01 2005-03-09 Chiron Srl Conjugation of streptococcal capsular saccharides
GB0502096D0 (en) * 2005-02-01 2005-03-09 Chiron Srl Purification of streptococcal capsular polysaccharide
EP3311836A1 (en) 2005-04-08 2018-04-25 Wyeth LLC Multivalent pneumococcal polysaccharide-protein conjugate composition
AU2011253684B8 (en) * 2005-04-08 2013-07-11 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
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PL2004225T3 (pl) 2006-03-22 2012-09-28 Novartis Ag Schematy immunizacji koniugatami meningokokowymi
US10828361B2 (en) 2006-03-22 2020-11-10 Glaxosmithkline Biologicals Sa Regimens for immunisation with meningococcal conjugates
GB0605757D0 (en) * 2006-03-22 2006-05-03 Chiron Srl Separation of conjugated and unconjugated components
US8808707B1 (en) 2006-05-08 2014-08-19 Wyeth Llc Pneumococcal dosing regimen
EP1872791A1 (en) 2006-06-30 2008-01-02 Institut Pasteur Use of bacterial polysaccharides for biofilm inhibition
EP2409995A3 (en) 2007-02-28 2012-08-15 Lipoxen Technologies Limited Reduction of endotoxin in polysialic acids
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CN101663327B (zh) * 2007-03-23 2014-05-07 惠氏公司 产生肺炎链球菌(streptococcus pneumoniae)荚膜多糖的缩短的纯化方法
GB0818453D0 (en) 2008-10-08 2008-11-12 Novartis Ag Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
JP5339243B2 (ja) * 2008-04-24 2013-11-13 株式会社微生物化学研究所 ストレプトコッカス・スイス感染症予防用ワクチン
WO2011005587A1 (en) * 2009-06-24 2011-01-13 University Of Dubuque Vaccine compositions and methods of use to protect against infectious disease
BR112013024322B1 (pt) * 2011-03-22 2020-04-22 Serum Inst India Ltd processo para preparação de polissacarídeos
US9400250B2 (en) 2013-09-30 2016-07-26 Han Sheng Biotech Co., Ltd. Method for analyzing mushrooms
MY186874A (en) * 2014-02-25 2021-08-26 Msd Wellcome Trust Hilleman Laboratories Pvt Ltd A novel downstream process for purifying polysaccharides
EP2942396A1 (en) 2014-05-07 2015-11-11 Novartis AG Polysaccharides produced by CPSC mutants
EP3034516A1 (en) * 2014-12-19 2016-06-22 Novartis AG Purification of streptococcal capsular polysaccharide
MY182282A (en) * 2015-05-04 2021-01-18 Pfizer Group b streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof
BE1025162B9 (fr) * 2016-12-06 2019-01-07 Glaxosmithkline Biologicals Sa Procede de purification pour les polysaccharides capsulaires
US11739356B2 (en) * 2017-05-05 2023-08-29 Serum Institute Of India Private Limited Method for removal of impurities from bacterial capsular polysaccharide based preparations
JP7111799B2 (ja) * 2017-07-05 2022-08-02 インベントプライズ リミテッド ライアビリティ カンパニー 溶菌酵素、接線流濾過、及びマルチモードクロマトグラフィを用いたワクチン生産のための多糖精製
CN111093650B (zh) 2017-09-07 2024-03-01 默沙东有限责任公司 肺炎球菌多糖及其在免疫原性多糖-载体蛋白缀合物中的用途
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Also Published As

Publication number Publication date
DK1051506T3 (da) 2010-09-13
AU754256B2 (en) 2002-11-07
KR100641490B1 (ko) 2006-10-31
EP1051506B2 (en) 2019-08-21
AU754256C (en) 2004-05-20
KR100757630B1 (ko) 2007-09-10
CA2316975A1 (en) 1999-07-01
US6248570B1 (en) 2001-06-19
HK1147506A1 (en) 2011-08-12
JP2010011862A (ja) 2010-01-21
ES2346022T3 (es) 2010-10-07
JP4435413B2 (ja) 2010-03-17
WO1999032653A9 (en) 1999-10-28
KR20060086978A (ko) 2006-08-01
EP1051506B8 (en) 2010-09-01
KR20010033494A (ko) 2001-04-25
EP1051506A1 (en) 2000-11-15
HUP0100623A3 (en) 2003-11-28
CZ302615B6 (cs) 2011-08-03
NO331100B1 (no) 2011-10-03
EP2226336A1 (en) 2010-09-08
DE69841676D1 (de) 2010-07-01
ES2611464T3 (es) 2017-05-09
JP2001526902A (ja) 2001-12-25
EP2226336B1 (en) 2016-10-19
EP3118225A1 (en) 2017-01-18
WO1999032653A1 (en) 1999-07-01
JP5144613B2 (ja) 2013-02-13
NO20003226D0 (no) 2000-06-21
HUP0100623A2 (hu) 2001-06-28
CZ20002373A3 (cs) 2000-12-13
AU2307199A (en) 1999-07-12
CA2316975C (en) 2009-03-24
EP1051506B1 (en) 2010-05-19
ATE468403T2 (de) 2010-06-15

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