JP4435413B2 - ワクチンとしてまたは結合体ワクチンとしてタンパク質に連結して使用するための細菌莢膜多糖の抽出および単離法 - Google Patents

ワクチンとしてまたは結合体ワクチンとしてタンパク質に連結して使用するための細菌莢膜多糖の抽出および単離法 Download PDF

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JP4435413B2
JP4435413B2 JP2000525570A JP2000525570A JP4435413B2 JP 4435413 B2 JP4435413 B2 JP 4435413B2 JP 2000525570 A JP2000525570 A JP 2000525570A JP 2000525570 A JP2000525570 A JP 2000525570A JP 4435413 B2 JP4435413 B2 JP 4435413B2
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capsular polysaccharide
polysaccharide
group
cps
derived
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ミチョン，フランシス
ブレイク，ミラン
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Baxter Healthcare SA
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
JP2000525570A 1997-12-23 1998-12-23 ワクチンとしてまたは結合体ワクチンとしてタンパク質に連結して使用するための細菌莢膜多糖の抽出および単離法 Expired - Lifetime JP4435413B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6860897P 1997-12-23 1997-12-23
US60/068,608 1997-12-23
PCT/US1998/027375 WO1999032653A1 (en) 1997-12-23 1998-12-23 Procedures for the extraction and isolation of bacterial capsular polysaccharides for use as vaccines or linked to proteins as conjugates vaccines

Related Child Applications (1)

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JP2009206304A Division JP5144613B2 (ja) 1997-12-23 2009-09-07 ワクチンとしてまたは結合体ワクチンとしてタンパク質に連結して使用するための細菌莢膜多糖の抽出および単離法

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JP4435413B2 true JP4435413B2 (ja) 2010-03-17

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JP2000525570A Expired - Lifetime JP4435413B2 (ja) 1997-12-23 1998-12-23 ワクチンとしてまたは結合体ワクチンとしてタンパク質に連結して使用するための細菌莢膜多糖の抽出および単離法
JP2009206304A Expired - Lifetime JP5144613B2 (ja) 1997-12-23 2009-09-07 ワクチンとしてまたは結合体ワクチンとしてタンパク質に連結して使用するための細菌莢膜多糖の抽出および単離法

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JP2009206304A Expired - Lifetime JP5144613B2 (ja) 1997-12-23 2009-09-07 ワクチンとしてまたは結合体ワクチンとしてタンパク質に連結して使用するための細菌莢膜多糖の抽出および単離法

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US (1) US6248570B1 (https=)
EP (3) EP2226336B1 (https=)
JP (2) JP4435413B2 (https=)
KR (2) KR100757630B1 (https=)
AT (1) ATE468403T2 (https=)
AU (1) AU754256C (https=)
CA (1) CA2316975C (https=)
CZ (1) CZ302615B6 (https=)
DE (1) DE69841676D1 (https=)
DK (1) DK1051506T4 (https=)
ES (2) ES2346022T3 (https=)
HU (1) HUP0100623A3 (https=)
NO (1) NO331100B1 (https=)
WO (1) WO1999032653A1 (https=)

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US6693188B2 (en) 2001-08-08 2004-02-17 Cargill Incorporated N-acetyl-D-glucosamine and process for producing N-acetyl-D-glucosamine
US8222232B2 (en) * 2001-02-16 2012-07-17 Cargill, Incorporated Glucosamine and N-acetylglucosamine compositions and methods of making the same fungal biomass
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GB0502095D0 (en) * 2005-02-01 2005-03-09 Chiron Srl Conjugation of streptococcal capsular saccharides
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EP3311836A1 (en) 2005-04-08 2018-04-25 Wyeth LLC Multivalent pneumococcal polysaccharide-protein conjugate composition
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US10828361B2 (en) 2006-03-22 2020-11-10 Glaxosmithkline Biologicals Sa Regimens for immunisation with meningococcal conjugates
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US8808707B1 (en) 2006-05-08 2014-08-19 Wyeth Llc Pneumococcal dosing regimen
EP1872791A1 (en) 2006-06-30 2008-01-02 Institut Pasteur Use of bacterial polysaccharides for biofilm inhibition
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CN101663327B (zh) * 2007-03-23 2014-05-07 惠氏公司 产生肺炎链球菌(streptococcus pneumoniae)荚膜多糖的缩短的纯化方法
GB0818453D0 (en) 2008-10-08 2008-11-12 Novartis Ag Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
JP5339243B2 (ja) * 2008-04-24 2013-11-13 株式会社微生物化学研究所 ストレプトコッカス・スイス感染症予防用ワクチン
WO2011005587A1 (en) * 2009-06-24 2011-01-13 University Of Dubuque Vaccine compositions and methods of use to protect against infectious disease
BR112013024322B1 (pt) * 2011-03-22 2020-04-22 Serum Inst India Ltd processo para preparação de polissacarídeos
US9400250B2 (en) 2013-09-30 2016-07-26 Han Sheng Biotech Co., Ltd. Method for analyzing mushrooms
MY186874A (en) * 2014-02-25 2021-08-26 Msd Wellcome Trust Hilleman Laboratories Pvt Ltd A novel downstream process for purifying polysaccharides
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MY182282A (en) * 2015-05-04 2021-01-18 Pfizer Group b streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof
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US11739356B2 (en) * 2017-05-05 2023-08-29 Serum Institute Of India Private Limited Method for removal of impurities from bacterial capsular polysaccharide based preparations
JP7111799B2 (ja) * 2017-07-05 2022-08-02 インベントプライズ リミテッド ライアビリティ カンパニー 溶菌酵素、接線流濾過、及びマルチモードクロマトグラフィを用いたワクチン生産のための多糖精製
CN111093650B (zh) 2017-09-07 2024-03-01 默沙东有限责任公司 肺炎球菌多糖及其在免疫原性多糖-载体蛋白缀合物中的用途
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DK1051506T3 (da) 2010-09-13
AU754256B2 (en) 2002-11-07
KR100641490B1 (ko) 2006-10-31
EP1051506B2 (en) 2019-08-21
AU754256C (en) 2004-05-20
KR100757630B1 (ko) 2007-09-10
CA2316975A1 (en) 1999-07-01
US6248570B1 (en) 2001-06-19
HK1147506A1 (en) 2011-08-12
JP2010011862A (ja) 2010-01-21
ES2346022T3 (es) 2010-10-07
WO1999032653A9 (en) 1999-10-28
KR20060086978A (ko) 2006-08-01
EP1051506B8 (en) 2010-09-01
KR20010033494A (ko) 2001-04-25
EP1051506A1 (en) 2000-11-15
HUP0100623A3 (en) 2003-11-28
CZ302615B6 (cs) 2011-08-03
NO331100B1 (no) 2011-10-03
EP2226336A1 (en) 2010-09-08
DE69841676D1 (de) 2010-07-01
ES2611464T3 (es) 2017-05-09
JP2001526902A (ja) 2001-12-25
EP2226336B1 (en) 2016-10-19
EP3118225A1 (en) 2017-01-18
DK1051506T4 (da) 2019-10-21
WO1999032653A1 (en) 1999-07-01
JP5144613B2 (ja) 2013-02-13
NO20003226D0 (no) 2000-06-21
HUP0100623A2 (hu) 2001-06-28
CZ20002373A3 (cs) 2000-12-13
AU2307199A (en) 1999-07-12
CA2316975C (en) 2009-03-24
EP1051506B1 (en) 2010-05-19
ATE468403T2 (de) 2010-06-15

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