KR100613950B1 - 복합요법에서 케모킨 수용체 길항물질과 사이클로스포린 - Google Patents

복합요법에서 케모킨 수용체 길항물질과 사이클로스포린 Download PDF

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KR100613950B1
KR100613950B1 KR1020017003199A KR20017003199A KR100613950B1 KR 100613950 B1 KR100613950 B1 KR 100613950B1 KR 1020017003199 A KR1020017003199 A KR 1020017003199A KR 20017003199 A KR20017003199 A KR 20017003199A KR 100613950 B1 KR100613950 B1 KR 100613950B1
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South Korea
Prior art keywords
rantes
met
cells
rejection
cyclosporin
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KR1020017003199A
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English (en)
Korean (ko)
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KR20010075060A (ko
Inventor
헤르만-조세프 그로네
피터제이. 넬손
아만다 프라우드푸트
티모시엔.씨. 웰스
Original Assignee
어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이.
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Publication of KR20010075060A publication Critical patent/KR20010075060A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
KR1020017003199A 1998-09-18 1999-09-16 복합요법에서 케모킨 수용체 길항물질과 사이클로스포린 Expired - Fee Related KR100613950B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98117697.7 1998-09-18
EP98117697A EP1000626A1 (en) 1998-09-18 1998-09-18 Chemokine receptor antagonist and cyclosporin in combined therapy

Publications (2)

Publication Number Publication Date
KR20010075060A KR20010075060A (ko) 2001-08-09
KR100613950B1 true KR100613950B1 (ko) 2006-08-18

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KR1020017003199A Expired - Fee Related KR100613950B1 (ko) 1998-09-18 1999-09-16 복합요법에서 케모킨 수용체 길항물질과 사이클로스포린

Country Status (23)

Country Link
US (1) US6902728B1 (enExample)
EP (2) EP1000626A1 (enExample)
JP (1) JP2003519082A (enExample)
KR (1) KR100613950B1 (enExample)
CN (1) CN1177613C (enExample)
AR (1) AR021810A1 (enExample)
AT (1) ATE227582T1 (enExample)
AU (1) AU766595B2 (enExample)
BR (1) BR9913846A (enExample)
CA (1) CA2344370A1 (enExample)
DE (1) DE69903964T2 (enExample)
DK (1) DK1113811T3 (enExample)
EA (1) EA003181B1 (enExample)
EE (1) EE04705B1 (enExample)
ES (1) ES2186411T3 (enExample)
HK (1) HK1041225B (enExample)
IL (2) IL141899A0 (enExample)
NO (1) NO20011371D0 (enExample)
PT (1) PT1113811E (enExample)
SI (1) SI1113811T1 (enExample)
UA (1) UA60379C2 (enExample)
WO (1) WO2000016796A1 (enExample)
ZA (1) ZA200101909B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7259136B2 (en) 1999-04-30 2007-08-21 Amylin Pharmaceuticals, Inc. Compositions and methods for treating peripheral vascular disease
US6740636B2 (en) 2000-07-31 2004-05-25 Schering Aktiengesellschaft Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection
LT5132B (lt) 2000-07-31 2004-05-25 Schering Aktiengesellschaft Nepeptidiniai ccr1 receptorių antagonistai derinyje su ciklosporinu a širdies transplanto atmetimui gydyti
MX2010001307A (es) 2007-08-02 2010-07-30 Novimmune Sa Anticuerpos anti-proteína regulada con la activación, expresada y secretada por los linfocitos t normales y metodos de uso de los mismos.
JP6733968B2 (ja) * 2015-08-31 2020-08-05 日立化成株式会社 腎移植後合併症を評価するための分子法
JP6624704B2 (ja) 2015-08-31 2019-12-25 日立化成株式会社 尿路上皮疾患の評価のための分子法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2207036A1 (en) * 1994-12-08 1996-06-13 Glaxo Group Limited Rantes peptide and fragments and compositions comprising it for treatment of inflammation
AU712606B2 (en) * 1995-08-09 1999-11-11 Schering Corporation Combined use of interleukin-10 and cyclosporin for immunosuppression therapy
EP0927167A1 (en) * 1996-08-14 1999-07-07 Warner-Lambert Company 2-phenyl benzimidazole derivatives as mcp-1 antagonists
WO1998006751A1 (en) * 1996-08-16 1998-02-19 Research Corporation Technologies, Inc. Mcp-3, rantes and mip-1alpha receptor antagonists

Also Published As

Publication number Publication date
EA003181B1 (ru) 2003-02-27
DE69903964T2 (de) 2003-03-27
SI1113811T1 (en) 2003-04-30
CA2344370A1 (en) 2000-03-30
CN1177613C (zh) 2004-12-01
EP1000626A1 (en) 2000-05-17
ZA200101909B (en) 2001-09-11
IL141899A0 (en) 2002-03-10
WO2000016796A1 (en) 2000-03-30
JP2003519082A (ja) 2003-06-17
ES2186411T3 (es) 2003-05-01
HK1041225A1 (en) 2002-07-05
NO20011371L (no) 2001-03-16
UA60379C2 (uk) 2003-10-15
IL141899A (en) 2007-12-03
AU6191499A (en) 2000-04-10
US6902728B1 (en) 2005-06-07
EP1113811B1 (en) 2002-11-13
HK1041225B (zh) 2005-04-22
KR20010075060A (ko) 2001-08-09
AR021810A1 (es) 2002-08-07
PT1113811E (pt) 2003-03-31
EE04705B1 (et) 2006-10-16
EA200100366A1 (ru) 2001-08-27
EP1113811A1 (en) 2001-07-11
EE200100159A (et) 2002-08-15
BR9913846A (pt) 2001-06-05
ATE227582T1 (de) 2002-11-15
DK1113811T3 (da) 2003-03-10
CN1319021A (zh) 2001-10-24
AU766595B2 (en) 2003-10-16
DE69903964D1 (en) 2002-12-19
NO20011371D0 (no) 2001-03-16

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