KR100613950B1 - 복합요법에서 케모킨 수용체 길항물질과 사이클로스포린 - Google Patents
복합요법에서 케모킨 수용체 길항물질과 사이클로스포린 Download PDFInfo
- Publication number
- KR100613950B1 KR100613950B1 KR1020017003199A KR20017003199A KR100613950B1 KR 100613950 B1 KR100613950 B1 KR 100613950B1 KR 1020017003199 A KR1020017003199 A KR 1020017003199A KR 20017003199 A KR20017003199 A KR 20017003199A KR 100613950 B1 KR100613950 B1 KR 100613950B1
- Authority
- KR
- South Korea
- Prior art keywords
- rantes
- met
- cells
- rejection
- cyclosporin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98117697.7 | 1998-09-18 | ||
| EP98117697A EP1000626A1 (en) | 1998-09-18 | 1998-09-18 | Chemokine receptor antagonist and cyclosporin in combined therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20010075060A KR20010075060A (ko) | 2001-08-09 |
| KR100613950B1 true KR100613950B1 (ko) | 2006-08-18 |
Family
ID=8232654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020017003199A Expired - Fee Related KR100613950B1 (ko) | 1998-09-18 | 1999-09-16 | 복합요법에서 케모킨 수용체 길항물질과 사이클로스포린 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6902728B1 (enExample) |
| EP (2) | EP1000626A1 (enExample) |
| JP (1) | JP2003519082A (enExample) |
| KR (1) | KR100613950B1 (enExample) |
| CN (1) | CN1177613C (enExample) |
| AR (1) | AR021810A1 (enExample) |
| AT (1) | ATE227582T1 (enExample) |
| AU (1) | AU766595B2 (enExample) |
| BR (1) | BR9913846A (enExample) |
| CA (1) | CA2344370A1 (enExample) |
| DE (1) | DE69903964T2 (enExample) |
| DK (1) | DK1113811T3 (enExample) |
| EA (1) | EA003181B1 (enExample) |
| EE (1) | EE04705B1 (enExample) |
| ES (1) | ES2186411T3 (enExample) |
| HK (1) | HK1041225B (enExample) |
| IL (2) | IL141899A0 (enExample) |
| NO (1) | NO20011371D0 (enExample) |
| PT (1) | PT1113811E (enExample) |
| SI (1) | SI1113811T1 (enExample) |
| UA (1) | UA60379C2 (enExample) |
| WO (1) | WO2000016796A1 (enExample) |
| ZA (1) | ZA200101909B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7259136B2 (en) | 1999-04-30 | 2007-08-21 | Amylin Pharmaceuticals, Inc. | Compositions and methods for treating peripheral vascular disease |
| US6740636B2 (en) | 2000-07-31 | 2004-05-25 | Schering Aktiengesellschaft | Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection |
| LT5132B (lt) | 2000-07-31 | 2004-05-25 | Schering Aktiengesellschaft | Nepeptidiniai ccr1 receptorių antagonistai derinyje su ciklosporinu a širdies transplanto atmetimui gydyti |
| MX2010001307A (es) | 2007-08-02 | 2010-07-30 | Novimmune Sa | Anticuerpos anti-proteína regulada con la activación, expresada y secretada por los linfocitos t normales y metodos de uso de los mismos. |
| JP6733968B2 (ja) * | 2015-08-31 | 2020-08-05 | 日立化成株式会社 | 腎移植後合併症を評価するための分子法 |
| JP6624704B2 (ja) | 2015-08-31 | 2019-12-25 | 日立化成株式会社 | 尿路上皮疾患の評価のための分子法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2207036A1 (en) * | 1994-12-08 | 1996-06-13 | Glaxo Group Limited | Rantes peptide and fragments and compositions comprising it for treatment of inflammation |
| AU712606B2 (en) * | 1995-08-09 | 1999-11-11 | Schering Corporation | Combined use of interleukin-10 and cyclosporin for immunosuppression therapy |
| EP0927167A1 (en) * | 1996-08-14 | 1999-07-07 | Warner-Lambert Company | 2-phenyl benzimidazole derivatives as mcp-1 antagonists |
| WO1998006751A1 (en) * | 1996-08-16 | 1998-02-19 | Research Corporation Technologies, Inc. | Mcp-3, rantes and mip-1alpha receptor antagonists |
-
1998
- 1998-09-18 EP EP98117697A patent/EP1000626A1/en not_active Withdrawn
-
1999
- 1999-09-16 CN CNB998111252A patent/CN1177613C/zh not_active Expired - Fee Related
- 1999-09-16 AT AT99948760T patent/ATE227582T1/de active
- 1999-09-16 SI SI9930157T patent/SI1113811T1/xx unknown
- 1999-09-16 DK DK99948760T patent/DK1113811T3/da active
- 1999-09-16 AR ARP990104655A patent/AR021810A1/es unknown
- 1999-09-16 ZA ZA200101909A patent/ZA200101909B/xx unknown
- 1999-09-16 ES ES99948760T patent/ES2186411T3/es not_active Expired - Lifetime
- 1999-09-16 DE DE69903964T patent/DE69903964T2/de not_active Expired - Lifetime
- 1999-09-16 EE EEP200100159A patent/EE04705B1/xx not_active IP Right Cessation
- 1999-09-16 EA EA200100366A patent/EA003181B1/ru not_active IP Right Cessation
- 1999-09-16 KR KR1020017003199A patent/KR100613950B1/ko not_active Expired - Fee Related
- 1999-09-16 PT PT99948760T patent/PT1113811E/pt unknown
- 1999-09-16 HK HK02103034.0A patent/HK1041225B/zh not_active IP Right Cessation
- 1999-09-16 EP EP99948760A patent/EP1113811B1/en not_active Expired - Lifetime
- 1999-09-16 IL IL141899??A patent/IL141899A0/xx active IP Right Grant
- 1999-09-16 BR BR9913846-8A patent/BR9913846A/pt not_active Application Discontinuation
- 1999-09-16 US US09/787,335 patent/US6902728B1/en not_active Expired - Fee Related
- 1999-09-16 AU AU61914/99A patent/AU766595B2/en not_active Ceased
- 1999-09-16 JP JP2000573757A patent/JP2003519082A/ja not_active Withdrawn
- 1999-09-16 UA UA2001042570A patent/UA60379C2/uk unknown
- 1999-09-16 CA CA002344370A patent/CA2344370A1/en not_active Abandoned
- 1999-09-16 WO PCT/EP1999/006844 patent/WO2000016796A1/en not_active Ceased
-
2001
- 2001-03-08 IL IL141899A patent/IL141899A/en not_active IP Right Cessation
- 2001-03-16 NO NO20011371A patent/NO20011371D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EA003181B1 (ru) | 2003-02-27 |
| DE69903964T2 (de) | 2003-03-27 |
| SI1113811T1 (en) | 2003-04-30 |
| CA2344370A1 (en) | 2000-03-30 |
| CN1177613C (zh) | 2004-12-01 |
| EP1000626A1 (en) | 2000-05-17 |
| ZA200101909B (en) | 2001-09-11 |
| IL141899A0 (en) | 2002-03-10 |
| WO2000016796A1 (en) | 2000-03-30 |
| JP2003519082A (ja) | 2003-06-17 |
| ES2186411T3 (es) | 2003-05-01 |
| HK1041225A1 (en) | 2002-07-05 |
| NO20011371L (no) | 2001-03-16 |
| UA60379C2 (uk) | 2003-10-15 |
| IL141899A (en) | 2007-12-03 |
| AU6191499A (en) | 2000-04-10 |
| US6902728B1 (en) | 2005-06-07 |
| EP1113811B1 (en) | 2002-11-13 |
| HK1041225B (zh) | 2005-04-22 |
| KR20010075060A (ko) | 2001-08-09 |
| AR021810A1 (es) | 2002-08-07 |
| PT1113811E (pt) | 2003-03-31 |
| EE04705B1 (et) | 2006-10-16 |
| EA200100366A1 (ru) | 2001-08-27 |
| EP1113811A1 (en) | 2001-07-11 |
| EE200100159A (et) | 2002-08-15 |
| BR9913846A (pt) | 2001-06-05 |
| ATE227582T1 (de) | 2002-11-15 |
| DK1113811T3 (da) | 2003-03-10 |
| CN1319021A (zh) | 2001-10-24 |
| AU766595B2 (en) | 2003-10-16 |
| DE69903964D1 (en) | 2002-12-19 |
| NO20011371D0 (no) | 2001-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| PN2301 | Change of applicant |
St.27 status event code: A-3-3-R10-R13-asn-PN2301 St.27 status event code: A-3-3-R10-R11-asn-PN2301 |
|
| A201 | Request for examination | ||
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
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| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
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| E13-X000 | Pre-grant limitation requested |
St.27 status event code: A-2-3-E10-E13-lim-X000 |
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| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
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| R17-X000 | Change to representative recorded |
St.27 status event code: A-3-3-R10-R17-oth-X000 |
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| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
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| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U12-oth-PR1002 Fee payment year number: 1 |
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| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
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| PG1601 | Publication of registration |
St.27 status event code: A-4-4-Q10-Q13-nap-PG1601 |
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| PN2301 | Change of applicant |
St.27 status event code: A-5-5-R10-R11-asn-PN2301 |
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| PN2301 | Change of applicant |
St.27 status event code: A-5-5-R10-R14-asn-PN2301 |
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| LAPS | Lapse due to unpaid annual fee | ||
| PC1903 | Unpaid annual fee |
St.27 status event code: A-4-4-U10-U13-oth-PC1903 Not in force date: 20090811 Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE |
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| PC1903 | Unpaid annual fee |
St.27 status event code: N-4-6-H10-H13-oth-PC1903 Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE Not in force date: 20090811 |